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Journal Articles

Identification of Optimized Peptide Nucleic Acid (PNA) Designs for Nuclease-Free Gene Editing in Sickle Cell Disease Hematopoietic Stem and Progenitor Cells (HSPCs)

Allen Ebens, PhD, Andrew Curd, B.Sc., Derek Sim, PhD, Elias Quijano, B.Sc., Florence Tam, M.Sc., James Coull, PhD,, Lily Huang, M.Sc., Mark Hayes, PhD, Marshall Fordyce, MD, Robert Pearson, B.Sc., Susan Whoriskey, PhD, Tumul Srivastava, PhD, Xiaojun Li, MD, Zhen Zhang, PhD

Blood (2019) 134 (Supplement_1): 4645.

https://doi.org/10.1182/blood-2019-127538

Published: 2019

Journal Articles

The PRIME Trial: PARP Inhibition in IDH Mutant Effectiveness Trial. a Phase II Study of Olaparib in Isocitrate Dehydrogenase (IDH) Mutant Relapsed/Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome

Namrata S Chandhok, MD, Wei Wei, MD PhD, Ranjit Bindra, MD PhD, Stephanie Halene, MD, Yu Shyr, Jing Li, PhD, Michael Berens, PhD, Chris Karlovich, PhD, S. Percy Ivy, MD, Thomas Prebet, MD PhD

Blood (2019) 134 (Supplement_1): 3909.

https://doi.org/10.1182/blood-2019-129168

Published: 2019

Journal Articles

TGF-B Inhibition Rescues Hematopoietic Defects in Fanconi Anemia

Joel S Greenberger, MD

Blood (2018) 132 (Supplement 1): SCI-29.

https://doi.org/10.1182/blood-2018-99-109479

Published: 2018

Journal Articles

Increased Longevity of Continuous Bone Marrow Cultures and Radioresistance of Bone Marrow Stromal Cells from SOD1 93A ALS (Amyotrophic Lateral Sclerosis) Mice

Andrew Henderson, Renee Fisher, Michael Epperly, PhD, Donna Shields, Lora Rigatti, Christopher Donnelly, Simon Watkins, Joel S. Greenberger, MD

Blood (2018) 132 (Supplement 1): 5679.

https://doi.org/10.1182/blood-2018-99-113580

Published: 2018

Journal Articles

3D-Tissue Engineered Bone Marrow (3DTEBM) Culture Predicts Clinical Efficacy of Drugs Better Than Regular Culture Systems in Multiple Myeloma

Amanda Jeske, BS, Abdel Kareem Azab, PhD

Blood (2017) 130 (Supplement 1): 3147.

https://doi.org/10.1182/blood.V130.Suppl_1.3147.3147

Published: 2017

Journal Articles

Radiation Resistance of C57Bl/6 Mouse Bone Marrow Stromal Cell Lines Induced By Apoptosis Inhibitor JP4-039 or Necroptosis Inhibitor Necrostatin-1, but Not By Simultaneous Administration of Both Mitigators

Zhiyang Wei, Michael Epperly, PhD, Donna Shields, Wen Hou, Darcy Franicola, Xichen Zhang, Renee Fisher, Hulya Bayir, Peter Wipf, Joel S. Greenberger, MD

Blood (2017) 130 (Supplement 1): 4945.

https://doi.org/10.1182/blood.V130.Suppl_1.4945.4945

Published: 2017

Journal Articles

Role of Bone Marrow Aspirate and Biopsy in the Diagnosis of HIV Patients Presenting with Low Blood Counts

Sandra Rajme, MD, Cesar Vargas-Serafin, MD, Roberta Demichelis, MD, Christianne Bourlon, MD

Blood (2017) 130 (Supplement 1): 1016.

https://doi.org/10.1182/blood.V130.Suppl_1.1016.1016

Published: 2017

Journal Articles

Radiation Resistance of Double Knockout (DKO) Smad3-/- Fancd2-/- (129/Sv) Mouse Bone Marrow Stromal Cell Lines

Kevin Keppel, Michael W. Epperly, PhD, Donna Shields, Wen Hou, Darcy Franicola, Zhang Xichen, Renee Fisher, Joel S. Greenberger, MD

Blood (2016) 128 (22): 3901.

https://doi.org/10.1182/blood.V128.22.3901.3901

Published: 2016

Journal Articles

Experience of Conventional Cytogenetics in Elderly Cytopenic Indian Patients Suspected with Myelodysplastic Syndromes

Bani Bandana Ganguly, PhD, Mandal Shouvik, MD, Nitin N Kadam, MD, Debasis Banerjee, MD, Sharmila Chandra, MD, Tuphan Kanti Dolai, MD, Mohan Agarwal, MDMNAMS

Blood (2016) 128 (22): 5488.

https://doi.org/10.1182/blood.V128.22.5488.5488

Published: 2016

Journal Articles

P27 Deficiency Results in Enhancing Hematopoiesis By Increasing IL22 Production from Bone Marrow Mesenchymal Stem Cells

Rui-Nan Lu, MD, PhD, Qian Wang, MS, Jianyong Li, MD PhD, Dengshun Miao, PhD

Blood (2016) 128 (22): 2665.

https://doi.org/10.1182/blood.V128.22.2665.2665

Published: 2016

Journal Articles

Critical Roles of Α-Type Lamins in Neutrophil Differentiation Revealed By Analyses of Lmna Trancriptional Regulation and Myeloid Models with Aberrant Lamin Α Expression

Margery G.H. Pelletier, BS, MSc, Krishnakumar Malu, MS, Klaudia Szymczak, MS, Anna M Barbeau, Gianna N Prata, BS, Kevin S O'Fallon, PhD, Peter Gaines, PhD

Blood (2016) 128 (22): 407.

https://doi.org/10.1182/blood.V128.22.407.407

Published: 2016

Journal Articles

EphB4/ephrinB2 ephrinB1 Interaction Mediated Chronic Myelogenous Leukemia Mesenchymal Stromal Cells Osteogenic Differentiation in Vitro and In Vivo

Li Lin, MD, Xu Na, PhD, Jiang Zhiwu, Lu Qisi, Zhou Xuan, Lu Ziyuan, Huang Jixian, MD, Li Yuling, He Bolin, Pan Chengyun, Li Peng, Liu Xiaoli, MD

Blood (2016) 128 (22): 1901.

https://doi.org/10.1182/blood.V128.22.1901.1901

Published: 2016

Journal Articles

Systematic Drug Repositioning By Integrating Transcriptome and Historical Clinical Data, Identification of Digoxin As a Novel Drug Reposition Candidate for High-Risk Myelodysplastic Syndromes

Huojun Cao, Zheng Yin, PhD, Shenyi Chen, Timothy Liu, Jiyong Liu, Yaping Hu, Hong Zhao, Lawrence Rice, MD, Swaminathan Padmanabhan Iyer, MD, Stephen Wong

Blood (2015) 126 (23): 4118.

https://doi.org/10.1182/blood.V126.23.4118.4118

Published: 2015

Journal Articles

Diffron C, a Novel Oligonucleotide Based Gene-Silencing Agent, Induces Terminal Differentiation in Primary Murine Cells

Christine Victoria Ichim, PhD, Dzana Dervovic, PhD, David Raymond Koos, PhD, Richard A. Wells, MD DPhil

Blood (2015) 126 (23): 4122.

https://doi.org/10.1182/blood.V126.23.4122.4122

Published: 2015

Journal Articles

Transformed Phenotype of Bone Marrow Stromal Cell Lines Derived from K14E7 Fancd2 -/- mice

Aranee Sivanathan, Xichen Zhang, Darcy Franicola, Shaonan Cao, Donna Shields, Michael W Epperly, PhD, Joel S. Greenberger, MD

Blood (2015) 126 (23): 4795.

https://doi.org/10.1182/blood.V126.23.4795.4795

Published: 2015

Journal Articles

Radiosensitivity of Fancd2 -/- mouse Bone Marrow Stromal Cells Is Altered By Abrogation of TGF-β Signaling

Katherine Chen, Darcy Franicola, Donna Shields, Michael W. Epperly, PhD, Xichen Zhang, Joel S. Greenberger, MD

Blood (2015) 126 (23): 4796.

https://doi.org/10.1182/blood.V126.23.4796.4796

Published: 2015

Journal Articles

Production of TGF-β Is Decreased in the Bone Marrow of Double Knockout (DKO) SMAD3 -/- Fancd2 -/- Mice

Virginia Falvello, Michael W. Epperly, PhD, Tracy Dixon, Darcy Franicola, Xichen Zhang, Joel S. Greenberger, MD

Blood (2015) 126 (23): 4798.

https://doi.org/10.1182/blood.V126.23.4798.4798

Published: 2015

Journal Articles

DNA Cross-Linking Agent Sensitivity of Fanconi Anemia (FA) Cells Is Preserved in Double Knockout (DKO) SMAD3 -/- Fancd2 -/- Mouse Cell Lines

Zean Chen, Darcy Franicola, Donna Shields, Michael W. Epperly, PhD, Xichen Zhang, Joel S. Greenberger, MD

Blood (2015) 126 (23): 4799.

https://doi.org/10.1182/blood.V126.23.4799.4799

Published: 2015

Journal Articles

3D Tissue-Engineered Bone Marrow Cultures Induce Drug Resistance, De-Differentiation and Cytokine Expression Changes in Multiple Myeloma

Pilar De La Puente, PhD, Barbara Muz, PhDMSc, Feda Azab, B.Pharm, Justin King, Ravi Vij, MD, Abdel Kareem Azab, BPharm, PhD

Blood (2014) 124 (21): 2069.

https://doi.org/10.1182/blood.V124.21.2069.2069

Published: 2014

Journal Articles

Conditional Knockout of LRP1 in Murine Megakaryocytes and Its Affects on Platelet Factor 4 Biology in Megakaryocytes

Michele P Lambert, MD, Liqing Xiao, Mortimer Poncz, MD

Blood (2014) 124 (21): 4150.

https://doi.org/10.1182/blood.V124.21.4150.4150

Published: 2014

NARROW

Identification of Optimized Peptide Nucleic Acid (PNA) Designs for Nuclease-Free Gene Editing in Sickle Cell Disease Hematopoietic Stem and Progenitor Cells (HSPCs)

The PRIME Trial: PARP Inhibition in IDH Mutant Effectiveness Trial. a Phase II Study of Olaparib in Isocitrate Dehydrogenase (IDH) Mutant Relapsed/Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome

TGF-B Inhibition Rescues Hematopoietic Defects in Fanconi Anemia

Increased Longevity of Continuous Bone Marrow Cultures and Radioresistance of Bone Marrow Stromal Cells from SOD1 93A ALS (Amyotrophic Lateral Sclerosis) Mice

3D-Tissue Engineered Bone Marrow (3DTEBM) Culture Predicts Clinical Efficacy of Drugs Better Than Regular Culture Systems in Multiple Myeloma

Radiation Resistance of C57Bl/6 Mouse Bone Marrow Stromal Cell Lines Induced By Apoptosis Inhibitor JP4-039 or Necroptosis Inhibitor Necrostatin-1, but Not By Simultaneous Administration of Both Mitigators

Role of Bone Marrow Aspirate and Biopsy in the Diagnosis of HIV Patients Presenting with Low Blood Counts

Radiation Resistance of Double Knockout (DKO) Smad3-/- Fancd2-/- (129/Sv) Mouse Bone Marrow Stromal Cell Lines

Experience of Conventional Cytogenetics in Elderly Cytopenic Indian Patients Suspected with Myelodysplastic Syndromes

P27 Deficiency Results in Enhancing Hematopoiesis By Increasing IL22 Production from Bone Marrow Mesenchymal Stem Cells

Critical Roles of Α-Type Lamins in Neutrophil Differentiation Revealed By Analyses of Lmna Trancriptional Regulation and Myeloid Models with Aberrant Lamin Α Expression

EphB4/ephrinB2 ephrinB1 Interaction Mediated Chronic Myelogenous Leukemia Mesenchymal Stromal Cells Osteogenic Differentiation in Vitro and In Vivo

Systematic Drug Repositioning By Integrating Transcriptome and Historical Clinical Data, Identification of Digoxin As a Novel Drug Reposition Candidate for High-Risk Myelodysplastic Syndromes

Diffron C, a Novel Oligonucleotide Based Gene-Silencing Agent, Induces Terminal Differentiation in Primary Murine Cells

Transformed Phenotype of Bone Marrow Stromal Cell Lines Derived from K14E7 Fancd2 -/- mice

Radiosensitivity of Fancd2 -/- mouse Bone Marrow Stromal Cells Is Altered By Abrogation of TGF-β Signaling

Production of TGF-β Is Decreased in the Bone Marrow of Double Knockout (DKO) SMAD3 -/- Fancd2 -/- Mice

DNA Cross-Linking Agent Sensitivity of Fanconi Anemia (FA) Cells Is Preserved in Double Knockout (DKO) SMAD3 -/- Fancd2 -/- Mouse Cell Lines

3D Tissue-Engineered Bone Marrow Cultures Induce Drug Resistance, De-Differentiation and Cytokine Expression Changes in Multiple Myeloma

Conditional Knockout of LRP1 in Murine Megakaryocytes and Its Affects on Platelet Factor 4 Biology in Megakaryocytes

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American Society of Hematology

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American Society of Hematology

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