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Journal Articles

Linking the KIR phenotype with STAT3 and TET2 mutations to identify chronic lymphoproliferative disorders of NK cells

Cédric Pastoret, Fabienne Desmots, Gaëlle Drillet, Simon Le Gallou, Marie-Laure Boulland, Alexia Thannberger, Anne-Violaine Doncker, Véronique Salaun, Gandhi Laurent Damaj, Richard Veyrat-Masson, Olivier Tournilhac, Aline Moignet, Céline Pangault, Mikaël Roussel, Thierry Fest, Thierry Lamy

Blood (2021) 137 (23): 3237–3250.

https://doi.org/10.1182/blood.2020006721

Published: 2021

Includes: Supplemental data

Journal Articles

Tracing the roots of CLPD-NK by TET2 and STAT3

Marco Herling, Till Braun

Blood (2021) 137 (23): 3156–3158.

https://doi.org/10.1182/blood.2020010542

Published: 2021

Journal Articles

STAT3 Mutations and Anemia with Pure Red Cell Aplasia Are the Distinctive Features of T Cell Receptor Gamma Delta Type Large Granular Lymphocyte Leukemia

Taku Yamane, Toru Kawakami, MD, Nodoka Sekiguchi, MD PhD, Jun Kobayashi, Toshimitsu Ueki, MD, Hikaru Kobayashi, MD PhD, Sayaka Nishina, Kaoko Sakai, MD, Hitoshi Sakai, MD, Kazuo Oshimi, MD, Yumiko Higuchi, PhD, Hideyuki Nakazawa, MD PhD, Fumihiro Ishida, MD PhD

Blood (2019) 134 (Supplement_1): 1500.

https://doi.org/10.1182/blood-2019-123614

Published: 2019

Journal Articles

Coexistence of B-Cell Dyscrasia with Large Granular Lymphocytic Leukemia

Hassan Awada, Jibran Durrani, Ashwin Kishtagari, MBBS, Valeria Visconte, PhD, Reda Z. Mahfouz, MD PhD

Blood (2019) 134 (Supplement_1): 3750.

https://doi.org/10.1182/blood-2019-132220

Published: 2019

Journal Articles

Whole Exome Sequencing Analysis in Chronic Lymphoproliferative Disorder of NK Cells (CLPD-NK) Patients Fails to Detect Significant Viral Load

Edoardo Giussani, Vanessa Rebecca Gasparini, Alessandro Coppe, Antonella Teramo, Andrea Binatti, Cristina Vicenzetto, Giulia Calabretto, Gregorio Barilà, Francesco Piazza, Gianpietro Semenzato, Stefania Bortoluzzi, PhD, Renato Zambello

Blood (2019) 134 (Supplement_1): 5214.

https://doi.org/10.1182/blood-2019-127907

Published: 2019

Journal Articles

Overexpression and Targeted Activation of the Protein Phosphatases SHP-1 Abrogates Survival Pathways in Large Granular Lymphocyte Leukemia (LGLL)

Mario Angelo Pagano, Elena Tibaldi, Giulia Calabretto, Antonella Teramo, Luca Dell'Amico, Gabriella Donà, Gregorio Barilà, Cristina Vicenzetto, Vanessa Rebecca Gasparini, Valentina Trimarco, Monica Facco, Francesco Piazza, Gianpietro Semenzato, Anna Maria Brunati, Renato Zambello

Blood (2019) 134 (Supplement_1): 2798.

https://doi.org/10.1182/blood-2019-129883

Published: 2019

Journal Articles

Literature Review of All Cases of Aggressive T-Cell Large Granular Lymphocytic Leukemia Cases and Report of an Additional Case

Vanessa Brunet, MD, Michel Pavic, MD, Sofia Marouan, Isabelle Fleury, MD MSc, FRCP, Jean-Francois Castilloux, MD

Blood (2018) 132 (Supplement 1): 5421.

https://doi.org/10.1182/blood-2018-99-111726

Published: 2018

Journal Articles

Multicentric MFI30 Study: Standardization of CD30 Expression By Flow Cytometry in Non-Hodgkin Lymphoma

Agathe Pruvot Debliquis, pharmD, Lucile Baseggio, MD, Marie-Christine Jacob, Sabrina Bouyer, Franck Genevieve, MD PhD, Julien Guy, MD, Caroline Mayeur-Rousse, MD, Nicolas Chapuis, PharmD, PhD, Hind Bennani, Thomas Matthes, MD, Bernard Drenou

Blood (2018) 132 (Supplement 1): 2869.

https://doi.org/10.1182/blood-2018-99-115990

Published: 2018

Journal Articles

Subset-Specific Recurrence of Mutations and Identification of Functional Modules Provides New Clues about the Pathogenesis of Large Granular Lymphocyte Leukemia

Alessandro Coppe, BSc, PhD, Emma I Andersson, MSc, Andrea Binatti, BSc, Vanessa R Gasparini, Sabrina Bortoluzzi, Michael J. Clemente, M.S., Marco Herling, MD PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP, Satu Mustjoki, MD PhD, Stefania Bortoluzzi, BSc, PhD

Blood (2016) 128 (22): 4117.

https://doi.org/10.1182/blood.V128.22.4117.4117

Published: 2016

Journal Articles

Acid Ceramidase Inhibition Impairs Tumor Progression in a Rat Model of LGL Leukemia

Su-Fern Tan, PhD, Xin Liu, MD PhD, Kathleen Broeg, B.S., Todd E. Fox, PhD, David J. Feith, PhD, Thomas P. Loughran, Jr., MD

Blood (2015) 126 (23): 1246.

https://doi.org/10.1182/blood.V126.23.1246.1246

Published: 2015

Journal Articles

FTY720 (Fingolimod) Targets the Sphingolipid Pathway and Induces Autophagy-Related Apoptosis in Human Natural Killer Large Granular Lymphocyte Leukemia

Francis Roland LeBlanc, B.S., Hong-Gang Wang, MD PhD, David J. Feith, PhD, Thomas P. Loughran, Jr., MD

Blood (2015) 126 (23): 1288.

https://doi.org/10.1182/blood.V126.23.1288.1288

Published: 2015

Journal Articles

Phenotypic Heterogeneity of Chronic Lymphoproliferative Disorder of NK Cells

Barila' Gregorio, MD, Antonella Teramo, PhD, Giulia Calabretto, BS, Chiara Ercolin, BS, Albana Lico, MD, Antonio Branca, MD, Tamara Berno, MD, Anna Cabrelle, BS, Elisa Boscaro, BS, Monica Facco, MS, Livio Trentin, MD, Francesco Piazza, MD, Gianpietro Semenzato, Renato Zambello

Blood (2015) 126 (23): 3876.

https://doi.org/10.1182/blood.V126.23.3876.3876

Published: 2015

Journal Articles

STAT5b Gene Mutations and Their Association with a Unique Immunophenotype of CD4+CD56+TCRαβ Type LGL Leukemia

Takahiro Tanahashi, Kazuyuki Matsuda, PhD, Nodoka Sekiguchi, MD PhD, Sayaka Nishina, MD, Noriko Senoo, MD, Kaoko Sakai, Hitoshi Sakai, MD, Toshiro Ito, MD PhD, Takeki Mitsui, MD, PhD, Yok Lam Kwong, MD, Fumihiro Ishida, MD PhD

Blood (2014) 124 (21): 1652.

https://doi.org/10.1182/blood.V124.21.1652.1652

Published: 2014

Journal Articles

Association Of Large Granular Lymphocytic Leukemia (LGL) With B-Cell Lymphoproliferative Disorders

Alan P. Z. Skarbnik, MD, Craig A. Portell, MD, Jaroslaw P. Maciejewski, MD, PhD, FACP, Ramon V. Tiu, MD, Brad Pohlman, MD, Manuel G. Afable, II, Anjali S. Advani, MD, Robert M Dean, MD, Brian T. Hill, MD, PhD, Leonard J. Horwitz, MD, Deepa Jagadeesh, MD, MPH, Alan E. Lichtin, Christy Samaras, DO, Mikkael A. Sekeres, MD, MS, Michael Millenson, MD, Mitchell R Smith, MD, PhD

Blood (2013) 122 (21): 1387.

https://doi.org/10.1182/blood.V122.21.1387.1387

Published: 2013

Journal Articles

LGL Disorders: From An Inflammatory-Mediated To a Self-Maintaining Proliferation

Antonella Teramo, PhD, Cristina Gattazzo, PhD, Francesca Passeri, BS, Gregorio Barilà, MD, Enrica Bovo, MD, Chiara Nardin, Alberto Campagnaro, Anna Cabrelle, PhD, Veronica Martini, PhD, Elisa Boscaro, PhD, Antonio Branca, MD, Monica Facco, PhD, Livio Trentin, MD, Gianpietro Semenzato, MD, Renato Zambello, MD

Blood (2013) 122 (21): 4889.

https://doi.org/10.1182/blood.V122.21.4889.4889

Published: 2013

Journal Articles

STAT3 Mutations in Large Granular Lymphocytic Leukemia

Annette Fasan, PhD, Wolfgang Kern, MD, Claudia Haferlach, MD, Torsten Haferlach, MD, Susanne Schnittger, PhD

Blood (2012) 120 (21): 1606.

https://doi.org/10.1182/blood.V120.21.1606.1606

Published: 2012

Journal Articles

Targeting Sphingosine Kinase 1 in NK-LGL Leukemia

Francis LeBlanc, Xin Liu, MD, PhD, Todd Fox, PhD, Mithun Shah, MD, PhD, Andrew Rogers, Lindsay Ryland, PhD, Mark Kester, PhD, Jong Yun, PhD, Thomas P. Loughran, Jr., MD

Blood (2012) 120 (21): 1313.

https://doi.org/10.1182/blood.V120.21.1313.1313

Published: 2012

Journal Articles

Discovery of STAT5b Mutations and Small Subclones of STAT3 Mutations in Large Granular Lymphocytic (LGL) Leukemia

Blood (2012) 120 (21): 871.

https://doi.org/10.1182/blood.V120.21.871.871

Published: 2012

Journal Articles

STAT3 Gene Mutations and the Association with Pure Red Cell Aplasia in Large Granular Lymphocyte Leukemia.

Nodoka Sekiguchi, MD, Kazuyuki Matsuda, PhD, Kayoko Momose, MD, Hideki Makishima, MD, PhD, Toshiro Ito, MD, Fumihiro Ishida, MD

Blood (2012) 120 (21): 2668.

https://doi.org/10.1182/blood.V120.21.2668.2668

Published: 2012

Journal Articles

Therapeutic Efficacy of FTY720 In a Rat Model of LGL Leukemia

Xin Liu, Aijun Liao, Hong-Gang Wang, Dhimant Desai, Shantu Amin, Thomas P. Loughran, Jr., MD

Blood (2010) 116 (21): 776.

https://doi.org/10.1182/blood.V116.21.776.776

Published: 2010

NARROW

Linking the KIR phenotype with STAT3 and TET2 mutations to identify chronic lymphoproliferative disorders of NK cells

Tracing the roots of CLPD-NK by TET2 and STAT3

STAT3 Mutations and Anemia with Pure Red Cell Aplasia Are the Distinctive Features of T Cell Receptor Gamma Delta Type Large Granular Lymphocyte Leukemia

Coexistence of B-Cell Dyscrasia with Large Granular Lymphocytic Leukemia

Whole Exome Sequencing Analysis in Chronic Lymphoproliferative Disorder of NK Cells (CLPD-NK) Patients Fails to Detect Significant Viral Load

Overexpression and Targeted Activation of the Protein Phosphatases SHP-1 Abrogates Survival Pathways in Large Granular Lymphocyte Leukemia (LGLL)

Literature Review of All Cases of Aggressive T-Cell Large Granular Lymphocytic Leukemia Cases and Report of an Additional Case

Multicentric MFI30 Study: Standardization of CD30 Expression By Flow Cytometry in Non-Hodgkin Lymphoma

Subset-Specific Recurrence of Mutations and Identification of Functional Modules Provides New Clues about the Pathogenesis of Large Granular Lymphocyte Leukemia

Acid Ceramidase Inhibition Impairs Tumor Progression in a Rat Model of LGL Leukemia

FTY720 (Fingolimod) Targets the Sphingolipid Pathway and Induces Autophagy-Related Apoptosis in Human Natural Killer Large Granular Lymphocyte Leukemia

Phenotypic Heterogeneity of Chronic Lymphoproliferative Disorder of NK Cells

STAT5b Gene Mutations and Their Association with a Unique Immunophenotype of CD4+CD56+TCRαβ Type LGL Leukemia

Association Of Large Granular Lymphocytic Leukemia (LGL) With B-Cell Lymphoproliferative Disorders

LGL Disorders: From An Inflammatory-Mediated To a Self-Maintaining Proliferation

STAT3 Mutations in Large Granular Lymphocytic Leukemia

Targeting Sphingosine Kinase 1 in NK-LGL Leukemia

Discovery of STAT5b Mutations and Small Subclones of STAT3 Mutations in Large Granular Lymphocytic (LGL) Leukemia

STAT3 Gene Mutations and the Association with Pure Red Cell Aplasia in Large Granular Lymphocyte Leukemia.

Therapeutic Efficacy of FTY720 In a Rat Model of LGL Leukemia

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American Society of Hematology

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American Society of Hematology

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