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Journal Articles

The Proteasomal Inhibitor Clioquinol Induces Apoptosis in Leukemia and Myeloma Cells by Inhibiting Histone Deacetylase Activity.

Biyin Cao, MD, PhD, Mingyun Shen, Mr., Depei Wu, Jianhong Du, MD, Jingyu Zhu, Suning Chen, Aining Sun, Xiaowen Tang, MD, PhD, Zhuan Xu, Yan Kong, MD. PhD, Xinliang Mao, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2449.
https://doi.org/10.1182/blood.V120.21.2449.2449
Published: 2012
Journal Articles

Clioquinol Arrests Cell Cycle at G1 Phase and Triggers Intrinsic Apoptosis In Myeloma and Leukemia Cells by Inhibiting Histone Deacetylases

Biyin Cao, Tingjun Hou, PhD, Suning Chen, Depei Wu, Aining Sun, Huiying Qiu, Wenjie Wang, Aaron Schimmer, MD, PhD, Xinliang Mao, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1836.
https://doi.org/10.1182/blood.V116.21.1836.1836
Published: 2010
Journal Articles

The Oral Off-Patent Antimicrobial Clioquinol Inhibits the Proteasome and Induces Cell Death in AML and Myeloma Cells through a Copper-Dependent Mechanism.

Xinliang Mao, PhD, Xiaoming Li, PhD, Rose Hurren, Bsc, Amudha Venugopal, PhD, Suzanne Trudel, MD, A. Keith Stewart, MD, Aaron D. Schimmer, MD, PHD
Journal: Blood
Blood (2007) 110 (11): 1595.
https://doi.org/10.1182/blood.V110.11.1595.1595
Published: 2007