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Journal Articles

The Distinctive Metabolic Environment of the Bone Marrow Niche Drives Leukemia Chemoresistance

Nick van Gastel, PhD, Jessica B. Spinelli, PhD, Azeem Sharda, MS, Amir Schajnovitz, PhD, Ninib Baryawno, PhD, Catherine S Rhee, PhD, Toshihiko Oki, MD PhD, Eliane Grace, Heather J. Soled, Charles Vidoudez, PhD, Sunia A. Trauger, PhD, Marcia C. Haigis, PhD, David T. Scadden, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3725.
https://doi.org/10.1182/blood-2019-124789
Published: 2019
Journal Articles

Metabolic Profiling Identifies De Novo Nucleotide Synthesis As a Potential Metabolic Vulnerability for Targeted Therapy Against Mantle Cell Lymphoma

Yixin Yao, PhD, Yang Liu, PhD, Hui Guo, PhD, Makhdum Ahmed, MD PhD MPH, Shabnam Bhuiyan, MSc, Krystle Nomie, PhD, Liang Zhang, MD PhD, Michael Wang, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2945.
https://doi.org/10.1182/blood-2018-99-112192
Published: 2018
Journal Articles

Untargeted Metabolomics Identifies Glutamine Metabolism As a Driver of Chemoresistance in Acute Myeloid Leukemia

Nick van Gastel, PhD, Amir Schajnovitz, PhD, Charles Vidoudez, PhD, Toshihiko Oki, MD PhD, Azeem Sharda, MS, Sunia A. Trauger, PhD, David T. Scadden, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2523.
https://doi.org/10.1182/blood.V130.Suppl_1.2523.2523
Published: 2017