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Journal Articles

Analysis of Molecular-Cellular Responses to Proteasome Inhibitors in Multiple Myeloma Patients; A Translational Approach of Proteasome Inhibitors In Vivo Effects from the Drosophila Experimental Model to Humans

Eleni-Dimitra Papanagnou, Tina Bagratuni, Efstathios Kastritis, Issidora Papassideri, Evangelos Terpos, MD, Meletios A. Dimopoulos, Ioannis P. Trougakos

Blood (2015) 126 (23): 3250.

https://doi.org/10.1182/blood.V126.23.3250.3250

Published: 2015

Journal Articles

Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila

Zachary J. Reitman, Sergey A. Sinenko, Eric P. Spana, Hai Yan

Blood (2015) 125 (2): 336–345.

https://doi.org/10.1182/blood-2014-05-577940

Published: 2015

Includes: Supplemental data

Journal Articles

Translating Findings of Proteasome Inhibitors Effects from the in Vivo Drosophila Experimental Model to Humans: The Paradigm of the Molecular-Cellular Responses to Bortezomib and Carfilzomib

Ioannis P. Trougakos, Eleni-Dimitra Papanagnou, Tina Bagratuni, Efstathios Kastritis, MD, Issidora S. Papassideri, Evangelos Terpos, Meletios A. Dimopoulos

Blood (2014) 124 (21): 4814.

https://doi.org/10.1182/blood.V124.21.4814.4814

Published: 2014

Journal Articles

Molecular Analyses Of The Effects Induced By Orally Administered Bortezomib In Drosophila Flies: A Novel In Vivo Experimental Platform To Screen For The Tissue- and Age-Dependent Effects Of Proteasome Inhibitors

Eleni N. Tsakiri, Evangelos Terpos, Gerasimos P. Sykiotis, Issidora S. Papassideri, Vassilis G. Gorgoulis, Dirk Bohmann, Meletios A. Dimopoulos, MD, Ioannis P. Trougakos

Blood (2013) 122 (21): 2910.

https://doi.org/10.1182/blood.V122.21.2910.2910

Published: 2013

Journal Articles

The Novel Proteasome Inhibitors Carfilzomib and Oprozomib Induce Milder Degenerative Effects Compared To Bortezomib When Administered Via Oral Feeding In An In Vivo Drosophila Experimental Model: A Biological Platform To Evaluate Safety/Efficacy Of Proteasome Inhibitors

Evangelos Terpos, Eleni N. Tsakiri, Efstathios Kastritis, Tina Bagratuni, Vassilis G. Gorgoulis, Ioannis P. Trougakos, Meletios A. Dimopoulos, MD

Blood (2013) 122 (21): 1930.

https://doi.org/10.1182/blood.V122.21.1930.1930

Published: 2013

Journal Articles

L3MBTL1: A Polycomb Protein At the Node of Crosstalk Between the BMP4 and Hippo Signaling Pathways in Erythropoiesis.

Fabiana Perna, MD, Ly P. Vu, Maria Themeli, MD, PhD, Ruben Hoya-Arias, PhD, Fan Liu, MD, PhD, Lan Wang, PhD, Nadia Gurvich, PhD, Todd Hricik, BS, Eirini P. Papapetrou, MD, PhD, Malcolm A.S. AS Moore, Ross L. Levine, Michel Sadelain, MD, PhD, Stephen Nimer, MD

Blood (2012) 120 (21): 2296.

https://doi.org/10.1182/blood.V120.21.2296.2296

Published: 2012

Journal Articles

Innovative Phase I/II Statistical Design in Combination Chemotherapy That Combines Toxicity and Efficacy Parameters to Increase Study Efficiency: Bendamustine and Idarubicin in De Novo Adult AML

Jack M. Lionberger, MD, PhD, Kathleen Shannon Dorcy, RN, MN, Ph.C, Carol Dean, RN, Nathan Holm, BS, Bart Lee Scott, MD, J. Kyle Wathen, PhD, Elihu H. Estey, MD, John M. Pagel, MD, PhD

Blood (2011) 118 (21): 1552.

https://doi.org/10.1182/blood.V118.21.1552.1552

Published: 2011

Journal Articles

Functional and Physical Interaction Between the Mismatch Repair and the FA-BRCA Pathways.

Stacy A Williams, James B Wilson, PhD, Allison P Clark, Alyssa N Mitson-Salazar, Allen E Bale, PhD, Nigel J Jones, PhD, Gary M Kupfer, M.D.

Blood (2010) 116 (21): 3370.

https://doi.org/10.1182/blood.V116.21.3370.3370

Published: 2010

Journal Articles

The Number of Very Small Embryonic Like Stem Cells (VSELs) Decreases During Aging In An IGF-1-Dependent Manner - a Novel Link Between Aging, Caloric Restriction, and the Size of the Stem Cell Pool

Dong-Myung Shin, Ph.D., Wu Wan, BS, Rui Liu, MB, BS, Janina Ratajczak, MD, PhD, Andrzej Bartke, Ph.D., Magdalena Kucia, PhD, Mariusz Z Ratajczak, MD, PhD, DSc

Blood (2010) 116 (21): 4796.

https://doi.org/10.1182/blood.V116.21.4796.4796

Published: 2010

Journal Articles

Genome-Wide Screening for Dominant Modifiers in Drosophila Identified New Cluster of Genes Involved in BCR-ABL Signalling and CML Progression.

Francesca Messa, PhD, Monica Pradotto, PhD, Francesca Arruga, PhD, Roberto Bernardoni, PhD, Enrico Bracco, PhD, Chiara Maffè, PhD, Emanuela Messa, MD, Sonia Carturan, PhD, Elisabetta Signorino, PhD, Elisabetta Greco, MD, Antonia Rotolo, MD, Ilaria Iacobucci, PhD, Giovanni Martinelli, MD, Giuseppe Saglio, MD, Daniela Cilloni, MD, PhD

Blood (2009) 114 (22): 2186.

https://doi.org/10.1182/blood.V114.22.2186.2186

Published: 2009

Journal Articles

Imatinib Induced Re-Activation of FoxO3 Transcription Factor in CML Is Responsible for the Induction of a Quiescent Status of CD34 Leukaemic Progenitor Cells.

Daniela Cilloni, MD, PhD, Cristina Panuzzo, PhD, Francesca Messa, PhD, Francesca Arruga, PhD, Enrico Bracco, PhD, Roberto Bernardoni, PhD, Sonia Carturan, PhD, Marisa Pautasso, MD, Emanuela Messa, MD, Alessandro Morotti, MD, Monica Pradotto, PhD, Ilaria Iacobucci, Thea Kalebic, MD, Giovanni Martinelli, MD, Giuseppe Saglio, MD

Blood (2008) 112 (11): 1090.

https://doi.org/10.1182/blood.V112.11.1090.1090

Published: 2008

Journal Articles

Identification of Genes Sustaining Bcr-Abl Oncogenic Signalling and CML Progression through a Genetic Tool Based on Human Bcr-Abl Transgenic Drosophila Melanogaster.

Daniela Cilloni, Francesca Messa, PhD, Roberto Bernardoni, PhD, Francesca Arruga, PhD, Monica Pradotto, PhD, Enrico Bracco, PhD, Cristina Panuzzo, PhD, Chiara Maffè, PhD, Emanuela Messa, MD, Ilaria Iacobucci, Thea Kalebic, MD, Giovanni Martinelli, MD, Michele Baccarani, MD, Giuseppe Saglio, MD

Blood (2008) 112 (11): 1091.

https://doi.org/10.1182/blood.V112.11.1091.1091

Published: 2008

Journal Articles

Molecular Dissection of Nup98-HoxA9 Oncogenic Activity Using Drosophila

Marc Therrien, PhD, Gino Laberge, PhD, Surapong Koonpaew, PhD, Gawa Bidla, PhD, Guy Sauvageau, MD, PhD

Blood (2008) 112 (11): 3785.

https://doi.org/10.1182/blood.V112.11.3785.3785

Published: 2008

Journal Articles

Development of a Genetic Tool Based on BCR-ABL Transgenic Drosophila Melanogaster for Identification of Genes Involved in CML Progression and Drug Testing.

Daniela Cilloni, MD, PhD, Francesca Messa, PhD, Francesca Arruga, PhD, Enrico Bracco, PhD, Paolo Nicoli, MD, Emanuela Messa, MD, Stefano Ulisciani, MD, Ilaria Iacobucci, PhD, Giovanni Martinelli, MD, Thea Kalebic, MD, Michele Baccarani, MD, Fabian Feiguin, MD, PhD, Giuseppe Saglio, MD

Blood (2007) 110 (11): 468.

https://doi.org/10.1182/blood.V110.11.468.468

Published: 2007

Journal Articles

Both the Activity and Stability of the Transcriptional Repressor PLZF Are Modified by the Class III Histone Deacetylase SIRT1.

Melanie-Jane McConnell, PhD, Emma Langley, PhD, Yolanda Martinez-Martinez, MS, Tony Kouzarides, PhD, Jonathan D. Licht, MD

Blood (2004) 104 (11): 360.

https://doi.org/10.1182/blood.V104.11.360.360

Published: 2004

NARROW

Analysis of Molecular-Cellular Responses to Proteasome Inhibitors in Multiple Myeloma Patients; A Translational Approach of Proteasome Inhibitors In Vivo Effects from the Drosophila Experimental Model to Humans

Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila

Translating Findings of Proteasome Inhibitors Effects from the in Vivo Drosophila Experimental Model to Humans: The Paradigm of the Molecular-Cellular Responses to Bortezomib and Carfilzomib

Molecular Analyses Of The Effects Induced By Orally Administered Bortezomib In Drosophila Flies: A Novel In Vivo Experimental Platform To Screen For The Tissue- and Age-Dependent Effects Of Proteasome Inhibitors

The Novel Proteasome Inhibitors Carfilzomib and Oprozomib Induce Milder Degenerative Effects Compared To Bortezomib When Administered Via Oral Feeding In An In Vivo Drosophila Experimental Model: A Biological Platform To Evaluate Safety/Efficacy Of Proteasome Inhibitors

L3MBTL1: A Polycomb Protein At the Node of Crosstalk Between the BMP4 and Hippo Signaling Pathways in Erythropoiesis.

Innovative Phase I/II Statistical Design in Combination Chemotherapy That Combines Toxicity and Efficacy Parameters to Increase Study Efficiency: Bendamustine and Idarubicin in De Novo Adult AML

Functional and Physical Interaction Between the Mismatch Repair and the FA-BRCA Pathways.

The Number of Very Small Embryonic Like Stem Cells (VSELs) Decreases During Aging In An IGF-1-Dependent Manner - a Novel Link Between Aging, Caloric Restriction, and the Size of the Stem Cell Pool

Genome-Wide Screening for Dominant Modifiers in Drosophila Identified New Cluster of Genes Involved in BCR-ABL Signalling and CML Progression.

Imatinib Induced Re-Activation of FoxO3 Transcription Factor in CML Is Responsible for the Induction of a Quiescent Status of CD34 Leukaemic Progenitor Cells.

Identification of Genes Sustaining Bcr-Abl Oncogenic Signalling and CML Progression through a Genetic Tool Based on Human Bcr-Abl Transgenic Drosophila Melanogaster.

Molecular Dissection of Nup98-HoxA9 Oncogenic Activity Using Drosophila

Development of a Genetic Tool Based on BCR-ABL Transgenic Drosophila Melanogaster for Identification of Genes Involved in CML Progression and Drug Testing.

Both the Activity and Stability of the Transcriptional Repressor PLZF Are Modified by the Class III Histone Deacetylase SIRT1.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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