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Journal Articles

Therapeutic Base Editing of Human Hematopoietic Stem Cells

Jing Zeng, MD, Yuxuan Wu, PhD, Chunyan Ren, PhD, Jasmine Bonanno, Anne H. Shen, Devlin Shea, Jason M Gehrke, PhD, John P Manis, MD, J. Keith Gehrke, Daniel E. Bauer, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 612.
https://doi.org/10.1182/blood-2019-129173
Published: 2019
Journal Articles

CUL1: Novel Therapeutic Target in Myeloid Neoplasms Harboring -7/Del(7q)

Vera Adema, PhD, Cassandra M Kerr, MS, Sunisa Kongkiatkamon, Jibran Durrani, Hassan Awada, MD, Stephan Hutter, PhD, Kevin Fung, Francesca Gould, Christina A. Snider, BA, Anjali S. Advani, MD, Hetty E. Carraway, MD MBA, Kevin R Kelly, MD PhD, Steffan T. Nawrocki, PhD, Yogenthiran Saunthararajah, MD, Jennifer S. Carew, PhD, Manja Meggendorfer, PhD, James G Phillips, PhD, Mikkael A. Sekeres, MD MS, Michael R. Savona, MD, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1281.
https://doi.org/10.1182/blood-2019-129196
Published: 2019
Journal Articles

Identification of the Genetic Variant Responsible for Variable Platelet CD36 Expression By Massively Parallel Reporter Assay

Namrata Madan, PhD, Andrew Ghazi, Xianguo Kong, MD, Edward Chen, PhD, Chad Shaw, PhD, Leonard C. Edelstein, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 520.
https://doi.org/10.1182/blood-2018-99-118607
Published: 2018
Journal Articles

Systemic Inflammation Induces Release of Cell-Free DNA from Hematopoietic and Parenchymal Cells in Mice and Human

Anna Kroeze, MD, Anne Jan van der Meer, MD, Arie J Hoogendijk, PhD, Aicha Ait Soussan, C. Ellen van der Schoot, MD PhD, Walter A Wuillemin, MD PhD, Carlijn Voermans, PhD, Tom van der Poll, MD PhD, Sacha S Zeerleder, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1107.
https://doi.org/10.1182/blood-2018-99-114468
Published: 2018
Journal Articles

Transcriptomic Analysis Reveals Erythroferrone Modulates BMP6 Signaling Pathways Involved in Iron Homeostasis and Metabolism

Reema Jasuja, PhD, Anagha Sawant, Debra D Pittman, MS, Jie Quan
Journal: Blood
Blood (2018) 132 (Supplement 1): 1049.
https://doi.org/10.1182/blood-2018-99-118724
Published: 2018
Journal Articles

CBFA2T3 Enhances Transcriptional Activity of RUNX1: Implication in Leukemia

Hélène Jakobczyk, Lydie Debaize, Anne-Gaëlle Rio, Jérémie Gaudichon, Aurélien Serandour, PhD, Stéphane Avner, PhD, Olivier Delalande, PhD, Gilles Salbert, PhD, Marie-Dominique Galibert, PharmD/PhD, Virginie Gandemer, MDPhD, Marie-Berengere Troadec, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3804.
https://doi.org/10.1182/blood.V130.Suppl_1.3804.3804
Published: 2017
Journal Articles

Expression of SATB2 in Acute Myeloid Leukemia and Its Prognostic Significance

Lihua Xu, Jingmei Ye, Xiaodan Luo, Huo Tan
Journal: Blood
Blood (2017) 130 (Supplement 1): 4986.
https://doi.org/10.1182/blood.V130.Suppl_1.4986.4986
Published: 2017
Journal Articles

Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging

Shweta Singh, Satyendra Singh, Stephen Gadomski, Lei Sun, Serguei Kozlov, Alex Pfaennenstein, Lino Tessarollo, Kimberly Klarmann, Jonathan Keller, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4943.
https://doi.org/10.1182/blood.V130.Suppl_1.4943.4943
Published: 2017
Journal Articles

Mediators of Disseminated Intravascular Coagulation: Molecular Mechanisms

Patricia C. Liaw, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): SCI-2.
https://doi.org/10.1182/blood.V130.Suppl_1.SCI-2.SCI-2
Published: 2017
Journal Articles

Identification of CHD4 As a Potential Therapeutic Target of Acute Myeloid Leukemia

Yaser Heshmati, Gözde Turköz, Aditya Harisankar, Sten Linnarsson, Marios Dimitriou, Indranil Sinha, Sören Lehmann, Hong Qian, PhD, Julian Walfridsson
Journal: Blood
Blood (2016) 128 (22): 1648.
https://doi.org/10.1182/blood.V128.22.1648.1648
Published: 2016
Journal Articles

Fine-Tuning Erythropoiesis By Competition Between Krüppel-like Factors for Promoters and Enhancers

Melissa Ilsley, BSc, Kevin R. Gillinder, PhD, Graham Magor, MB BS (Hons), Merlin Crossley, DPhil, Andrew C Perkins, PhD
Journal: Blood
Blood (2016) 128 (22): 1036.
https://doi.org/10.1182/blood.V128.22.1036.1036
Published: 2016
Journal Articles

The Impact of Maintenance Lenalidomide on the Mutational Status of the Myeloma Clone at Relapse in the NCRI Myeloma XI Trial for Newly Diagnosed Multiple Myeloma Patients (NDMM)

John R Jones, MD, Niels Weinhold, PhD, Shweta S. Chavan, PhD, Charlotte Pawlyn, MB BChir, Lorenzo Melchor, PhD, David A Cairns, MSc, PhD, Dil B Begum, Charlotte Smith, Sidra Ellis, Amy Price, Amy L Sherborne, Brian A Walker, PhD, Christopher P Wardell, PhD, Gordon Cook, MD PhD, Matthew W Jenner, MD, Nigel H Russell, MD, Mark T Drayson, MD PhD, Roger G Owen, MD PhD, Faith E Davies, MD, Martin F Kaiser, MD, Graham H Jackson, MD PhD, Walter M Gregory, PhD, Mel Greaves, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4412.
https://doi.org/10.1182/blood.V128.22.4412.4412
Published: 2016
Journal Articles

Genetic Variations in Calicheamicin Pathway Genes Are Predictors of Gemtuzumab Ozogamicin Response in AML Patients: Results from COG-AAML0531 Study

Jatinder K Lamba, PhD, Lata Chauhan, PhD, Richard Aplenc, MD PhD, Maggie Skrypek, MD, Jessica Pollard, MD, Todd A. Alonzo, PhD, Y-C Wang, Irwin D. Bernstein, MD, Alan S. Gamis, MD MPH, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1260.
https://doi.org/10.1182/blood.V126.23.1260.1260
Published: 2015
Journal Articles

Comprehensive Quantitative Proteomic Profiling of the Pharmacodynamic Changes Induced By MLN4924 in Acute Myeloid Leukemia Cells Reveals Rational Targets for Combination Therapy

Valeria Visconte, PhD, Steffan T. Nawrocki, PhD, Kevin R. Kelly, MD PhD, Yingchun Han, MD, Anthony Possemato, Sean Beausoleil, Aziz Nazha, MD, Jaroslaw P. Maciejewski, MD PhD, Hetty E. Carraway, MD MBA, Anjali S. Advani, MD, Mikkael A. Sekeres, MD MS, Jennifer S. Carew, PhD
Journal: Blood
Blood (2015) 126 (23): 1271.
https://doi.org/10.1182/blood.V126.23.1271.1271
Published: 2015
Journal Articles

In silico Tissue-Based Expression Analysis of YY1 and Cancer Stem Cell (CSC) Transcription Factors in Hematological Malignancies: Unraveling New Therapeutic Targets

Samantha Kaufhold, Hermes Garban, MD PhD, Benjamin Bonavida, PhD
Journal: Blood
Blood (2015) 126 (23): 4814.
https://doi.org/10.1182/blood.V126.23.4814.4814
Published: 2015
Journal Articles

Identification and Mechanistic Characterization of CMPD1 As a Selective Sensitizer of Histone Deacetylase Inhibitors in Myeloid Malignancies

James M Bogenberger, PhD, Nanna Hansen, M.S., Devora Delman, B.S., Ruben A. Mesa, Raoul Tibes, MD
Journal: Blood
Blood (2015) 126 (23): 3689.
https://doi.org/10.1182/blood.V126.23.3689.3689
Published: 2015
Journal Articles

hnRNP K Overexpression Synergizes with Mutant NPM1 to Drive Acute Myeloid Leukemia Progression

Miguel Gallardo, PhD, Hun Ju Lee, MD, Xiaorui Zhang, Laura R. Pageon, Asha Multani, Markus Reschke, PhD, John G Clohessy, Alfonso Quintás-Cardama, MD, Michael Andreeff, MD PhD, Steven M. Kornblau, MD, Pier Paolo Pandolfi, MD PhD, Sean M. Post, PhD
Journal: Blood
Blood (2014) 124 (21): 2382.
https://doi.org/10.1182/blood.V124.21.2382.2382
Published: 2014
Journal Articles

Mechanistic Insights into Forced Chromatin Looping Mediated Activation of Fetal Globin Gene Expression

Caroline Bartman, Gerd A. Blobel, MD PhD, Jeremy Grevet, Chris C.S. Hsiung, B.A., Jeremy W. Rupon, MD PhD, Arjun Raj, PhD
Journal: Blood
Blood (2014) 124 (21): 331.
https://doi.org/10.1182/blood.V124.21.331.331
Published: 2014
Journal Articles

hnRNP K : A Tumor Suppressor or Oncogene?

Miguel Gallardo, PhD, Hun Ju Lee, MD, Carlos E. Bueso-Ramos, MD PhD, Xiaorui Zhang, Laura R. Pageon, Asha Multani, Inmaculada Rapado, Alfonso Quintás-Cardama, MD, Steven M. Kornblau, MD, Joaquin Martinez-Lopez, Sean M. Post, PhD
Journal: Blood
Blood (2014) 124 (21): 259.
https://doi.org/10.1182/blood.V124.21.259.259
Published: 2014
Journal Articles

Distinct Patterns of Genomic Alterations in Adult T-Cell Leukemia-Lymphoma Endemic in the Western World

Agustin Pimentel, MD, Andrea O'Hara, PhD, Rosangela de Lima, PhD, Suying Xu, post-doctorate, fellow, PhD, Ngoc Toomey, Carlos Brites, Yao-Shan Fan, Juan Carlos Ramos, MD
Journal: Blood
Blood (2014) 124 (21): 1698.
https://doi.org/10.1182/blood.V124.21.1698.1698
Published: 2014