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Journal Articles

Single Injection of Cord Blood Regulatory T Cells Can Delay the Manifestations of Systemic Lupus Erythematosus

Mi-Ae Lyu, PhD, Joseph D. Khoury, MD, Mitsutaka Nishimoto, MD PhD, Ke Zeng, MD PhD, Meixian Huang, Swaminathan P. Iyer, MD, Simrit Parmar, MBBS

Blood (2019) 134 (Supplement_1): 1938.

https://doi.org/10.1182/blood-2019-131436

Published: 2019

Journal Articles

Cord Blood Regulatory T Cells Prevent Mutiple Myeloma Progression By Suppressing Inflammation

Mitsutaka Nishimoto, MD PhD, Ke Zeng, MD PhD, Meixian Huang, Mi-Ae Lyu, PhD, Nina D. Shah, MD, Swaminathan P. Iyer, MD, Robert Z. Orlowski, MD, PhD, Simrit Parmar, MBBS

Blood (2019) 134 (Supplement_1): 3095.

https://doi.org/10.1182/blood-2019-128418

Published: 2019

Journal Articles

Rara Is a Druggable Super-Enhancer Regulated Dependency in Pediatric AML

Alfred S. Daramola, MS, Monika Perez, BS, Oscar S. Sias-Garcia, MS, Maci S. Terrell, BS, Helen Y Wei, BS, Nikitha Cherayil, BS, Alexandra McLean Stevens, MD PhD, Charles Y Lin, PhD, Joanna S. Yi, MD

Blood (2019) 134 (Supplement_1): 281.

https://doi.org/10.1182/blood-2019-125425

Published: 2019

Journal Articles

Mesothelin Targeting Bites for Pediatric AML: In Vivo Efficacy and Specificity

Anilkumar Gopalakrishnapillai, PhD, Colin Correnti, PhD, Anne Kisielewski, BS, Allison Kaeding, MD, Soheil Meshinchi, MD PhD, E. Anders Kolb, MD, Sonali Barwe, PhD MSc

Blood (2019) 134 (Supplement_1): 3925.

https://doi.org/10.1182/blood-2019-130941

Published: 2019

Journal Articles

Efficacy of Targeted Therapy in Novel Pre-Clinical in Vitro and In Vivo Models of Richter Transformation-Diffuse Large B-Cell Lymphoma (RT-DLBCL)

Vrajesh Karkhanis, PhD, Warren Fiskus, BSc,PhD, Christopher Peter Mill, PhD BA, Abhishek Maiti, MBBS, Bernardo H Lara, James V Maher, Isean Bhalla, Nancy Shao, Michael R Green, PhD, Joseph D. Khoury, MD, Kapil N. Bhalla, MD

Blood (2019) 134 (Supplement_1): 3961.

https://doi.org/10.1182/blood-2019-132041

Published: 2019

Journal Articles

Enhancing the Effect of CLL-1 CAR T Cells with Interleukin-15 for Treatment of Acute Myeloid Leukemia

Pinar Ataca Atilla, MD, Haruko Tashiro, MD PhD, Mary Kathryn McKenna, PhD, Madhuwanti Srinivasan, Brian Wesley Simons, Alexandra McLean Stevens, MD PhD, Michele Redell, MD PhD, Maksim Mamonkin, PhD, Malcolm K. Brenner, MD PhD, Erden Atilla, MD

Blood (2019) 134 (Supplement_1): 3912.

https://doi.org/10.1182/blood-2019-127953

Published: 2019

Journal Articles

Geranylgeranyl Diphosphate Synthase Inhibitor and Proteasome Inhibitor Combination Therapy in Multiple Myeloma

Staci L. Haney, PhD, Michelle L. Varney, MS, Lynette M. Smith, PhD, Sarah A. Holstein, MD PhD

Blood (2019) 134 (Supplement_1): 4417.

https://doi.org/10.1182/blood-2019-129244

Published: 2019

Journal Articles

T Cells Educated By DC/AML Fusions in the Context of 4-1BB Costimulation As a Potent Strategy for Adoptive Cellular Therapy

Jessica Liegel, MD, Dina Stroopinsky, PhD, Haider Ghiasuddin, Adam Morin, Marzia Capelletti, PhD MMSc, Shira Orr, PhD, Maryam Rahimian, MD, Lina Bisharat, Shufen Meng, MD, Myrna Nahas, MD, Matthew Weinstock, MD, Donald Kufe, MD, Jacalyn Rosenblatt, MD, David E. Avigan, MD

Blood (2019) 134 (Supplement_1): 2673.

https://doi.org/10.1182/blood-2019-131491

Published: 2019

Journal Articles

Panobinostat (LBH589) in Combination with the β-Catenin Inhibitor Tegavivint (BC2059) Exerts Significant Anti-Myeloma Activity Both in Vitro and In Vivo

Ioanna Savvidou, MD, Tiffany Khong, BSc, PhD, Sophie Whish, Tara Sepehrizadeh, Sridurga Mithraprabhu, PhD MSc, Michael DeVeer, BSc, PhD, Andrew Spencer, DM

Blood (2019) 134 (Supplement_1): 5540.

https://doi.org/10.1182/blood-2019-126468

Published: 2019

Journal Articles

A Novel Monoclonal Antibody Combination Plus DC/AML Fusion Vaccine Eradicates AML in an Immunocompetent Murine Model

Dina Stroopinsky, PhD, Jessica Liegel, MD, Kathleen M. Mahoney, MD PhD, Jacalyn Rosenblatt, MD, Benjamin L. Ebert, MD PhD, Richard M. Stone, MD, Maryam Rahimian, MD, Myrna Nahas, MD, Shira Orr, PhD, Marzia Capelletti, PhD MMSc, Matthew Weinstock, MD, Salvia Jain, MD, Lina Bisharat, MA, Haider Ghiasuddin, BA, Adam Morin, BA, Donald Kufe, MD, Gordon J Freeman, PhD, David E. Avigan, MD

Blood (2018) 132 (Supplement 1): 1446.

https://doi.org/10.1182/blood-2018-99-120259

Published: 2018

Journal Articles

Par-4 Overexpression Impedes Leukemogenesis in the Eµ-TCL1 Leukemia Model

Joseph Thomas Greene, BS, Rahul Ramaswamy, Mary K McKenna, BS, Rajeswaran Mani, DVM,PhD, Frank Frissora, MS, Ronni Wasmuth, BS, Minh Tran, BS, Xiaokui Mo, PhD MAS, Carlo M. Croce, MD, Vivek Rangnekar, PhD, John C. Byrd, MD, Subbarao Bondada, PhD, Natarajan Muthusamy, DVM,PhD

Blood (2017) 130 (Supplement 1): 1223.

https://doi.org/10.1182/blood.V130.Suppl_1.1223.1223

Published: 2017

Journal Articles

Novel Bispecific Antibody Targeting CD45 and 90 Y-DOTA Is Effective Therapy for Acute Myeloid Leukemia in Preclinical Murine Models

Johnnie J. Orozco, MD PhD, Aimee Kenoyer, BS, Yukang Lin, PhD, Darrell R. Fisher, PhD, Donald K. Hamlin, BS, D. Scott Wilbur, PhD, Alexandra Hernandez, BS, Rosario Guel, Margaret E. Nartea, Shyril O'Steen, PhD, Mark D Hylarides, PhD, Brian G Till, MD, Damian J. Green, MD, Ajay K. Gopal, MD, Kelly D Orcutt, PhD, Karl Dane Wittrup, PhD, Brenda M. Sandmaier, MD, John M. Pagel, MD PhD, Oliver W. Press, MD PhD

Blood (2017) 130 (Supplement 1): 1355.

https://doi.org/10.1182/blood.V130.Suppl_1.1355.1355

Published: 2017

Journal Articles

Pharmacologic Inhibition of PI3Kδ Prolongs Survival of Mutant Shp2 E76K -Expressing Mice

Lisa Deng, Elizabeth L Virts, PhD, Rebecca J Chan, MD PhD

Blood (2017) 130 (Supplement 1): 1240.

https://doi.org/10.1182/blood.V130.Suppl_1.1240.1240

Published: 2017

Journal Articles

Iron Overload Decreases Engraftment of Mice Receiving Allogeneic or Syngeneic Bone Marrow Transplant

Amy Tang, MD, Francesca La Carpia, PhD, Boguslaw S. Wojczyk, PhD, Abdelhadi Rebaa, PhD, Stuart P. Weisberg, MD PhD, Steven Spitalnik, MD, Eldad A. Hod, MD

Blood (2017) 130 (Supplement 1): 4442.

https://doi.org/10.1182/blood.V130.Suppl_1.4442.4442

Published: 2017

Journal Articles

Ruxolitinib Rescues Mice from Lethal Interferon Beta Toxicity and TLS

Kah-Whye Peng, PhD, Linh Pham, Lianwen Zhang, PhD, Rebecca Nace, Nathan Jenks, Michael Steele, Alysha Newsom, Ronald Marler, DVM, PhD, Martha Q Lacy, MD, Stephen J. Russell, MD PhD

Blood (2017) 130 (Supplement 1): 1807.

https://doi.org/10.1182/blood.V130.Suppl_1.1807.1807

Published: 2017

Journal Articles

Hyper-Activation of the Adenosinergic Axis in the Eμ-TCL1 Chronic Lymphocytic Leukemia Mouse Model Offers Therapeutic Opportunities

Tiziana Vaisitti, PhD, Sara Serra, PhD, Cinzia Bologna, PhD, Nicoletta Vitale, PhD, Stefania Gobessi, PhD BS, Dimitar G Efremov, MD PhD, Silvia Deaglio, MD

Blood (2017) 130 (Supplement 1): 1721.

https://doi.org/10.1182/blood.V130.Suppl_1.1721.1721

Published: 2017

Journal Articles

The Novel BET Inhibitor PLX51107 Has In Vitro and In Vivo Activity Against Acute Myeloid Leukemia

Nicole R. Grieselhuber, MD PhD, Shaneice R. Mitchell, BS, Shelley Orwick, BS, Bonnie K. Harrington, DVM, Virginia M. Goettl, DVM, PhD, Alison R. Walker, MD MPH, Bhavana Bhatnagar, DO, Alice S. Mims, MD MSCR, Rebecca B. Klisovic, MD, Sumithra Vasu, MBBS, William Blum, MD, James S. Blachly, MD, David M. Lucas, PhD, Ramiro Garzon, MD, Rosa Lapalombella, PhD, John C. Byrd, MD

Blood (2016) 128 (22): 3941.

https://doi.org/10.1182/blood.V128.22.3941.3941

Published: 2016

Journal Articles

A Novel Bispecific CD38 Antibody Eradicates Multiple Myeloma in a Mouse Model Following Yttrium-90-DOTA Capture

Blood (2015) 126 (23): 118.

https://doi.org/10.1182/blood.V126.23.118.118

Published: 2015

Journal Articles

Integrative Analysis of the Mutational Landscape of Mouse and Human AML Identifies Functionally Relevant Leukemia Disease Alleles

Megan A. Hatlen, PhD, Kanika Arora, MS, Vladimir Vacic, PhD, Ewa A. Grabowska, BS, Willey Liao, BS, Bridget Riley-Gillis, PhD, Dayna M. Oschwald, BS, Lan Wang, PhD, Jacob E. Joergens, Alan H. Shih, MD PhD, Franck Rapaport, PhD, Shengqing Gu, PhD, Francesca Voza, BS, Takashi Asai, MD PhD, Benjamin Neel, MD PhD, Michael G. Kharas, PhD, Mithat Gonen, PhD, Ross L. Levine, MD, Stephen D. Nimer, MD

Blood (2015) 126 (23): 1247.

https://doi.org/10.1182/blood.V126.23.1247.1247

Published: 2015

Journal Articles

SIRPαFc, a CD47-Blocking Cancer Immunotherapeutic, Sensitizes Malignant B Cells to Macrophage-Mediated Destruction

Natasja Nielsen Viller, Saman Maleki Vareki, Karen Dodge, Hui Chen, Vivian Lee, Vien Chai, Xinli Pang, Mark Wong, Suzanne Trudel, MD, Rene Figueredo, Macarena Pampillo, James Koropatnick, Penka S. Petrova, Robert A. Uger

Blood (2015) 126 (23): 2191.

https://doi.org/10.1182/blood.V126.23.2191.2191

Published: 2015

NARROW

Single Injection of Cord Blood Regulatory T Cells Can Delay the Manifestations of Systemic Lupus Erythematosus

Cord Blood Regulatory T Cells Prevent Mutiple Myeloma Progression By Suppressing Inflammation

Rara Is a Druggable Super-Enhancer Regulated Dependency in Pediatric AML

Mesothelin Targeting Bites for Pediatric AML: In Vivo Efficacy and Specificity

Efficacy of Targeted Therapy in Novel Pre-Clinical in Vitro and In Vivo Models of Richter Transformation-Diffuse Large B-Cell Lymphoma (RT-DLBCL)

Enhancing the Effect of CLL-1 CAR T Cells with Interleukin-15 for Treatment of Acute Myeloid Leukemia

Geranylgeranyl Diphosphate Synthase Inhibitor and Proteasome Inhibitor Combination Therapy in Multiple Myeloma

T Cells Educated By DC/AML Fusions in the Context of 4-1BB Costimulation As a Potent Strategy for Adoptive Cellular Therapy

Panobinostat (LBH589) in Combination with the β-Catenin Inhibitor Tegavivint (BC2059) Exerts Significant Anti-Myeloma Activity Both in Vitro and In Vivo

A Novel Monoclonal Antibody Combination Plus DC/AML Fusion Vaccine Eradicates AML in an Immunocompetent Murine Model

Par-4 Overexpression Impedes Leukemogenesis in the Eµ-TCL1 Leukemia Model

Novel Bispecific Antibody Targeting CD45 and 90 Y-DOTA Is Effective Therapy for Acute Myeloid Leukemia in Preclinical Murine Models

Pharmacologic Inhibition of PI3Kδ Prolongs Survival of Mutant Shp2 E76K -Expressing Mice

Iron Overload Decreases Engraftment of Mice Receiving Allogeneic or Syngeneic Bone Marrow Transplant

Ruxolitinib Rescues Mice from Lethal Interferon Beta Toxicity and TLS

Hyper-Activation of the Adenosinergic Axis in the Eμ-TCL1 Chronic Lymphocytic Leukemia Mouse Model Offers Therapeutic Opportunities

The Novel BET Inhibitor PLX51107 Has In Vitro and In Vivo Activity Against Acute Myeloid Leukemia

A Novel Bispecific CD38 Antibody Eradicates Multiple Myeloma in a Mouse Model Following Yttrium-90-DOTA Capture

Integrative Analysis of the Mutational Landscape of Mouse and Human AML Identifies Functionally Relevant Leukemia Disease Alleles

SIRPαFc, a CD47-Blocking Cancer Immunotherapeutic, Sensitizes Malignant B Cells to Macrophage-Mediated Destruction

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American Society of Hematology

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