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Journal Articles

Results of a Flow Cytometry Assay Measuring Oxidative Stress Relief As a Predictor of Immunomodulatory Drugs (IMIDs) Sensitivity in Myeloma

Luke Mountjoy, DO, Sinto Chirackal, PhD, Tania Jain, MD, Marlene Girardo, MS, Jeremy Larsen, MD, Rafael Fonseca, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4443.
https://doi.org/10.1182/blood-2018-99-113710
Published: 2018
Journal Articles

Lenalidomide Inhibits Thioredoxin Reductase (TrxR) in Multiple Myeloma (MM) Cells but Direct Inhibition of Trxr and Thioredoxin (Trx) Can Bypass Requirement of Cereblon (CRBN)

Sinto Sebastian Chirackal, PhD, Esteban Braggio, PhD, Yuan Xiao Zhu, PhD, Chang-Xin Shi, PhD, Scott Van Wier, Gregory Ahmann, Veronica Gonzalez-Calle, MD, Marta Chesi, PhD, Leif Bergsagel, MD, Keith Stewart, M.B., Ch.B., Rafael Fonseca, MD
Journal: Blood
Blood (2016) 128 (22): 4482.
https://doi.org/10.1182/blood.V128.22.4482.4482
Published: 2016
Journal Articles

Pharmacological Inhibitors of LSD1 Promote Differentiation of Myeloid Leukemia Cells through a Mechanism Independent of Histone Demethylation

James T Lynch, PhD, Gary J Spencer, PhD, William J Harris, PhD, Alba Maiques-Díaz, PhD, Filippo Ciceri, PhD, Xu Huang, PhD, Tim C P Somervaille, PhD FRCP, FRCPath
Journal: Blood
Blood (2014) 124 (21): 267.
https://doi.org/10.1182/blood.V124.21.267.267
Published: 2014