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Journal Articles

Alterations of Gut Microbiome Accelerate Multiple Myeloma Progression By Increasing the Relative Abundances of Nitrogen Recycling Bacteria

Xingxing Jian, PhD, Yinghong Zhu, Jian Ouyang, Qian Lei, Jiliang Xia, PhD, Jingyu Zhang, Jiaojiao Guo, Jinuo Wang, MD, Jingchao Lin, Mingming Su, Yongjun Guan, Guancheng Li, PhD, Minghua Wu, PhD, Jian Li, MD, Juanjuan Xiang, PhD, Lu Xie, PhD, Lugui Qiu, MD PhD, Wei Jia, PhD, Wen Zhou, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 688.
https://doi.org/10.1182/blood-2019-125051
Published: 2019
Journal Articles

Glutamine Depletion By Addicted Myeloma Cells Inhibits Osteoblastic Differentiation of Bone Marrow Mesenchymal Stromal Cells Limiting Asparagine Availability: A Possible New Mechanism for Myeloma Bone Disease

Martina Chiu, PhD, Denise Toscani, PhD, Emanuela Vicario, PhD, Roberta Andreoli, PhD, Giuseppe Taurino, MS, Valentina Marchica, MS, Paola Storti, PhD, Massimiliano Bianchi, PhD, Ovidio Bussolati, MD PhD, Nicola Giuliani
Journal: Blood
Blood (2019) 134 (Supplement_1): 4339.
https://doi.org/10.1182/blood-2019-128034
Published: 2019
Journal Articles

Myeloma-Induced Alterations of Glutamine Metabolism Impair Bone Microenvironment Niche in Multiple Myeloma Patients

Denise Toscani, PhD, Martina Chiu, PhD, Giuseppe Taurino, MS, Emanuela Vicario, MS, Valentina Marchica, MS, Fabrizio Accardi, MD, Anna Benedetta Dalla Palma, MD, Paola Storti, PhD, Gaetano Donofrio, PhD, Franco Aversa, MD, Ovidio Bussolati, MD PhD, Nicola Giuliani, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4481.
https://doi.org/10.1182/blood-2018-99-111337
Published: 2018
Journal Articles

Resistance to Nutrient Deprivation Via Metabolic Re-Programming As Mechanism of 'Metastasis' Promotion in Multiple Myeloma

Ioanna Savvidou, MD, Sahan Chandrasekara, MD, Maoshan Chenn, PhD, Tiffany Khong, BSc, PhD, Andrew Spencer, MBBS, FRACP, FRCPA, DM
Journal: Blood
Blood (2018) 132 (Supplement 1): 3218.
https://doi.org/10.1182/blood-2018-99-112802
Published: 2018
Journal Articles

Ammonium Production and Glutamine-Addiction of Myeloma Cells: New Attractive Targets in Multiple Myeloma

Fabrizio Accardi, MD, Martina Chiu, Marina Bolzoni, Paola Storti, PhD, Katia Todoerti, PhD, Luca Agnelli, Massimiliano Ferrari, MD, Gabriele Missale, MD, Franco Aversa, MD, Ovidio Bussolati, MD PhD, Nicola Giuliani, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2067.
https://doi.org/10.1182/blood.V124.21.2067.2067
Published: 2014
Journal Articles

Antitumor Activity Of The Glutaminase Inhibitor CB-839 In Hematological Malignances

Francesco Parlati, PhD, Shoshana Bromley-Dulfano, BS, Susan Demo, PhD, Julie Janes, MS, Matt Gross, BS, Evan Lewis, PhD, Andy MacKinnon, PhD, Mirna Rodriguez, BS, Jinfu Yang, PhD, Frances Zhao, MS, Mark Bennett, PhD
Journal: Blood
Blood (2013) 122 (21): 4226.
https://doi.org/10.1182/blood.V122.21.4226.4226
Published: 2013