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Journal Articles

Targeting MET and FGFR in Relapsed or Refractory Acute Myeloid Leukemia: Preclinical, Clinical, and Correlative Studies

Jacqueline S Garcia, MD, Helen I. Gandler, Geoffrey Fell, MS, Ashlee J. Fiore, Donna S Neuberg, ScD, Adrienne Anderson, Kelsey O'Day, Marlise Luskin, MDMS, Martha Wadleigh, MD, Eric S. Winer, MD, Ilene Galinsky, Daniel J. DeAngelo, MD, David A. Frank, MD PhD, Richard M. Stone, MD

Blood (2019) 134 (Supplement_1): 2549.

https://doi.org/10.1182/blood-2019-126224

Published: 2019

Journal Articles

The MP0250-CP201 Mirror Study: A Phase 2 Study Update of MP0250 Plus Bortezomib and Dexamethasone in Relapse/Refractory Multiple Myeloma (RRMM) Patients Previously Exposed to Proteasome Inhibitors and Immunomodulatory Drugs

Norbert Grząśko, MD PhD, Stefan Knop, Hartmut Goldschmidt, MD, Marc S Raab, MD PhD, Jan Dürig, Sara Bringhen, Mattia D'Agostino, MD, Barbara Gamberi, Elena Rivolti, MD, Angelo Vacca, MD PhD, Roberto Ria, MD, Artur Jurczyszyn, MD, Jorge Castellano Acosta, MD, Doris Lang, Guy Lemaillet, PhD, Bansod Sudhir, MD, Monika Szarejko, MD

Blood (2019) 134 (Supplement_1): 1899.

https://doi.org/10.1182/blood-2019-129827

Published: 2019

Journal Articles

Meta-Analysis Illustrates Role of Interferon-γ Signaling in Multiple Myeloma Pathogenesis

Jihad Aljabban, MMSc, BA, Nabeal Aljabban, BS, Mohamad Mukhtar, BS, Saad Syed, BS, Ross Wanner, BS, Francesca Cottini, MD, Tiffany Hughes, BS, PhD, Kareem Saleh, BS, Evan C Catton, Taylor Gonzalez, Maryam Panahiazar, PhD, Dexter Hadley, MD PhD, Don M. Benson, Jr., MD PhD

Blood (2018) 132 (Supplement 1): 4510.

https://doi.org/10.1182/blood-2018-99-112265

Published: 2018

Journal Articles

Plasma Fms-Related Tyrosine Kinase 3 Ligand (Flt3L) Levels at Diagnosis Correlate with Treatment Response in Chronic Myeloid Leukemia

Bhagwan Yadav, PhD, Mette Ilander, PhD, Anna Kreutzman, PhD, Henrik Hjorth-Hansen, MD, Satu Mustjoki, MDPhD

Blood (2017) 130 (Supplement 1): 1602.

https://doi.org/10.1182/blood.V130.Suppl_1.1602.1602

Published: 2017

Journal Articles

A Single-Cell Approach to Unraveling Abnormal Megakaryocyte Differentiation and Function in Myelofibrosis

Bethan Psaila, MD PhD, Elisabeth F Heuston, PhD, Dragana Milojkovic, MBBS, PhD, Jens Lichtenberg, Stacie M Anderson, Ronald Hoffman, MD, Irene Roberts, MD, Adam J Mead, MD PhD, David M. Bodine, PhD, NISC Comparative Sequencing Program, Nikolaos Barkas, PhD

Blood (2017) 130 (Supplement 1): 490.

https://doi.org/10.1182/blood.V130.Suppl_1.490.490

Published: 2017

Journal Articles

Prognostic Value of the Parameters of Myeloma Bone Disease Signaling in Patients with Newly Diagnosed Multiple Myeloma Treated with Proteasome Inhibitors

Jiri Minarik, MD PhD, Zuzana Hermanova, Jan Hrbek, Pavla Petrova, Patrik Flodr, Petra Krhovska, Tomas Pika, Jaroslav Bacovsky, Miroslav Herman, Vlastimil Scudla

Blood (2016) 128 (22): 5603.

https://doi.org/10.1182/blood.V128.22.5603.5603

Published: 2016

Journal Articles

Composite Biomarker Panel in Prediction of Severity and Diagnosis of Acute GvHD with T- Depleted Allogeneic Stem Cell Transplants- Single Centre Pilot Study

San San Min, MBBS, MSc, FRCPath, Varun Mehra, MBBS, MRCP(UK), FRCPath, Jennifer Clay, Gemma Cross, Abdel Douiri, PhD, Tracy Dew, Victoria T Potter, Tanya Basu, MRCP, MBBS, PhDMA, Roy Sherwood, BSc, MSc, DPhil, Royce Vincent, MBBS, MSc, MD FRCPath, M. Mansour Ceesay, MRCP, FRCPath, MDRes), Antonio Pagliuca, MBBS MA FRCP FRCPath

Blood (2016) 128 (22): 2234.

https://doi.org/10.1182/blood.V128.22.2234.2234

Published: 2016

Journal Articles

Transforming Growth Factor- β1 Signaling in Vascular Endothelial Cells Inhibits Hematopoietic Stem Cell Regeneration

Derek Zachman, MS, Devorah C Goldman, PhD, Chandan Guha, MD PhD, Beth Wilmot, William H. Fleming, MD PhD

Blood (2016) 128 (22): 1493.

https://doi.org/10.1182/blood.V128.22.1493.1493

Published: 2016

Journal Articles

Assessment of the Parameters of Myeloma Bone Disease Signaling to the Extent of Skeletal Involvement, Bone Mineral Turnover and Activity of Multiple Myeloma

Jiri Minarik, Zuzana Hermanova, Pavla Petrova, Jana Zapletalova, Jan Hrbek, Petra Pusciznova, Jaroslav Bacovsky, Tomas Pika, Miroslav Herman, Vlastimil Scudla

Blood (2015) 126 (23): 1754.

https://doi.org/10.1182/blood.V126.23.1754.1754

Published: 2015

Journal Articles

Methylation of HAI-2/SPINT2 in Bone Marrow Mesenchymal Stromal Cells of MDS and AML Patients Affects Hematopoietic Stem Cell Survival and Adhesion

Fernanda Marconi Roversi, PhD, Nathalia Moreno Cury, MSc, Matheus Rodrigues Lopes, MSc, Fernando Vieira Pericole, MD, Marisa Claudia Alvarez Prax, PhD, Karla Priscila Ferro, PhD, Patricia Favaro, PhD, José Andres Yunes, PhD, Sara T. Olalla Saad, MD, PhD

Blood (2015) 126 (23): 2847.

https://doi.org/10.1182/blood.V126.23.2847.2847

Published: 2015

Journal Articles

The Contribution of Bone Marrow Stromal Cells to Leukemia Evolution: Differential Support of Leukemia Cell Growth at Diagnosis and Remission

Shlomit Yehudai-Reshef, PhD, Shira Attias, Tal Gabay, Rawan Sabah, Yael Morgenstern, MD PhD, Tsila Zuckerman, MD

Blood (2015) 126 (23): 5419.

https://doi.org/10.1182/blood.V126.23.5419.5419

Published: 2015

Journal Articles

Evidence for Induction of a Tumor-Metastasis-Receptive Microenvironment in Bone Marrow and Other Organs As an Unwanted and Underestimated Side Effect of Chemotherapy/Radiotherapy

Pranesh Gunjal, MS, Gabriela Schneider, PhD, Sham Kakar, PhD, Magdalena Kucia, PhD, Mariusz Z Ratajczak, MD PhD

Blood (2014) 124 (21): 2925.

https://doi.org/10.1182/blood.V124.21.2925.2925

Published: 2014

Journal Articles

Role of Hepatocyte Growth Factor in Endothelial-Dependent Hematopoietic Stem Cell Regeneration

Derek K Zachman, Devorah C Goldman, PhD, Kimberly L Hamlin, Chandan Guha, MD PhD, William H. Fleming, MD PhD

Blood (2014) 124 (21): 4369.

https://doi.org/10.1182/blood.V124.21.4369.4369

Published: 2014

Journal Articles

Bone Marrow-Derived Mesenchymal Stem Cells Overexpressing Akt1 Protect Against ConA-Induced Liver Injury in Mice

Lukun Zhou, MD, Shuang Liu, PhD, Chuanyi M. Lu, MD, Jianfeng Yao, MD, Yuyan Shen, MD, Xin Yang, MD, Sizhou Feng, MD, Mingzhe Han, MD

Blood (2014) 124 (21): 5805.

https://doi.org/10.1182/blood.V124.21.5805.5805

Published: 2014

Journal Articles

Early Apoptotic Cells (ApoCell) As Prophylaxis of Graft-Versus-Host Disease in Myeloablative HLA-Matched Allogeneic Bone Marrow Transplantation Is Safe and Effective: 1 Year Follow-up

Dror Mevorach, Zuckerman Tzila, Arnon Nagler, MD, Jacob M. Rowe, MD, Reuven Or

Blood (2014) 124 (21): 5866.

https://doi.org/10.1182/blood.V124.21.5866.5866

Published: 2014

Journal Articles

Prognostic Value Of Plasma Biomarkers Compared To Urinary Proteome Patterns

Christin Human, Sylvia Borchers, PhD, Michael Stadler, MD, Helmut Diedrich, Jürgen Krauter, MD, PhD, Christine Falk, Arnold Ganser, Eva M Weissinger, MD

Blood (2013) 122 (21): 4593.

https://doi.org/10.1182/blood.V122.21.4593.4593

Published: 2013

Journal Articles

JAK Inhibition Reduces CD25 high CD27 + FOXp3 + T Regulatory Cells and Causes a Silencing Of T Effector Cells In Patients With Myeloproliferative Neoplasms Whilst Promoting a TH17 Phenotype

Clodagh Keohane, MD, Shahram Y Kordasti, MD, PhD, Thomas Seidl, Pilar Perez Abellan, Nicholas Shaun B. Thomas, PhD, Ghulam J Mufti, FRCP, FRCPath, Claire N Harrison, DM, FRCP, FRCPath, Donal McLornan, MD, PhD

Blood (2013) 122 (21): 4092.

https://doi.org/10.1182/blood.V122.21.4092.4092

Published: 2013

Journal Articles

Bone Marrow Microenvironment Induces Stem Cell-Like Phenotype In Acute Myeloid Leukemia

Venkata L Battula, Ph.D., Juliana M Benito, PhD, Anitha Somanchi, Seshagiri Duvvuri, Lauren Hodgson, Ye Chen, PhD, Wencai Ma, Ph.D., Richard E. Davis, M.D., Ian K. McNiece, PhD, Elizabeth J Shpall, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD

Blood (2013) 122 (21): 2457.

https://doi.org/10.1182/blood.V122.21.2457.2457

Published: 2013

Journal Articles

Downregulation Of SPINT2 Expression In Stromal Cells From Myelodysplastic Syndrome Patients Increases HGF and SDF-1 Secretion and Promotes Cell-Cell Adhesion By Alteration In Integrin Expression

Fernanda Marconi Roversi, PhD, Matheus Rodrigues Lopes, MSc, João Agostinho Machado-Neto, MSc, Ana Leda Longhini, PhD, Adriana da Silva Santos Duarte, PhD, Bruna Palodetto, MSc, Flavia Adolfo Corrocher, MSc, Paula de Melo Campos, MD, Mariana Ozello Baratti, PhD, Fernando V Pericole, MD, Patricia Favaro, PhD, Fabiola Traina, M.D., Ph.D., Sara Teresinha Saad, MD, PhD

Blood (2013) 122 (21): 2763.

https://doi.org/10.1182/blood.V122.21.2763.2763

Published: 2013

Journal Articles

Phase II Study Of The c-MET Inhibitor ARQ 197 (Tivantinib) In Patients With Relapsed Or Relapsed/Refractory Multiple Myeloma (RRMM)

Robert Z. Orlowski, M.D., Ph.D, Shadia Zaman, Ph.D., Sheeba K. Thomas, M.D., Raymond Alexanian, M.D., Jatin J. Shah, M.D., Donna M. Weber, M.D., Michael Wang, MD, Ashley N. Holloway, R.N., Veerabhadran Baladandayuthapani, Ph.D., Heather Yan Lin, Ph.D., Min Fu, Christine M. Stellrecht, Ph.D., Claudia Morales de Partovi, B.S., Varsha Gandhi, PhD

Blood (2013) 122 (21): 1953.

https://doi.org/10.1182/blood.V122.21.1953.1953

Published: 2013

NARROW

Targeting MET and FGFR in Relapsed or Refractory Acute Myeloid Leukemia: Preclinical, Clinical, and Correlative Studies

The MP0250-CP201 Mirror Study: A Phase 2 Study Update of MP0250 Plus Bortezomib and Dexamethasone in Relapse/Refractory Multiple Myeloma (RRMM) Patients Previously Exposed to Proteasome Inhibitors and Immunomodulatory Drugs

Meta-Analysis Illustrates Role of Interferon-γ Signaling in Multiple Myeloma Pathogenesis

Plasma Fms-Related Tyrosine Kinase 3 Ligand (Flt3L) Levels at Diagnosis Correlate with Treatment Response in Chronic Myeloid Leukemia

A Single-Cell Approach to Unraveling Abnormal Megakaryocyte Differentiation and Function in Myelofibrosis

Prognostic Value of the Parameters of Myeloma Bone Disease Signaling in Patients with Newly Diagnosed Multiple Myeloma Treated with Proteasome Inhibitors

Composite Biomarker Panel in Prediction of Severity and Diagnosis of Acute GvHD with T- Depleted Allogeneic Stem Cell Transplants- Single Centre Pilot Study

Transforming Growth Factor- β1 Signaling in Vascular Endothelial Cells Inhibits Hematopoietic Stem Cell Regeneration

Assessment of the Parameters of Myeloma Bone Disease Signaling to the Extent of Skeletal Involvement, Bone Mineral Turnover and Activity of Multiple Myeloma

Methylation of HAI-2/SPINT2 in Bone Marrow Mesenchymal Stromal Cells of MDS and AML Patients Affects Hematopoietic Stem Cell Survival and Adhesion

The Contribution of Bone Marrow Stromal Cells to Leukemia Evolution: Differential Support of Leukemia Cell Growth at Diagnosis and Remission

Evidence for Induction of a Tumor-Metastasis-Receptive Microenvironment in Bone Marrow and Other Organs As an Unwanted and Underestimated Side Effect of Chemotherapy/Radiotherapy

Role of Hepatocyte Growth Factor in Endothelial-Dependent Hematopoietic Stem Cell Regeneration

Bone Marrow-Derived Mesenchymal Stem Cells Overexpressing Akt1 Protect Against ConA-Induced Liver Injury in Mice

Early Apoptotic Cells (ApoCell) As Prophylaxis of Graft-Versus-Host Disease in Myeloablative HLA-Matched Allogeneic Bone Marrow Transplantation Is Safe and Effective: 1 Year Follow-up

Prognostic Value Of Plasma Biomarkers Compared To Urinary Proteome Patterns

JAK Inhibition Reduces CD25 high CD27 + FOXp3 + T Regulatory Cells and Causes a Silencing Of T Effector Cells In Patients With Myeloproliferative Neoplasms Whilst Promoting a TH17 Phenotype

Bone Marrow Microenvironment Induces Stem Cell-Like Phenotype In Acute Myeloid Leukemia

Downregulation Of SPINT2 Expression In Stromal Cells From Myelodysplastic Syndrome Patients Increases HGF and SDF-1 Secretion and Promotes Cell-Cell Adhesion By Alteration In Integrin Expression

Phase II Study Of The c-MET Inhibitor ARQ 197 (Tivantinib) In Patients With Relapsed Or Relapsed/Refractory Multiple Myeloma (RRMM)

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American Society of Hematology

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