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Journal Articles

FVIII Protein Is Not Detectable in Human PBMCs or Livers from Dogs with an Intron-22 Inversion Mutation: Implications for FVIII Immunogenicity and Tolerance

Devi Gunasekera, MBBS, Pooja Vir, PhD, Ahmad Faisal Karim, PhD, Margaret V. Ragni, MD MPH, Elizabeth P. Merricks, PhD, Timothy C. Nichols, MD, Kathleen P. Pratt, PhD

Blood (2019) 134 (Supplement_1): 630.

https://doi.org/10.1182/blood-2019-124880

Published: 2019

Journal Articles

VCAM1 Confers Innate Immune Tolerance on Hematopoietic and Leukemic Stem Cells

Sandra Pinho, PhD, Qiaozhi Wei, PhD, Maria Maryanovich, PhD, Halley Pierce, PhD, Fumio Nakahara, MD PhD, Jianing Xu, PhD, Daniel K. Borger, MS, Dachuan Zhang, PhD, Amit Verma, MBBS, Paul S. Frenette, MD

Blood (2019) 134 (Supplement_1): 524.

https://doi.org/10.1182/blood-2019-123431

Published: 2019

Journal Articles

Immune Tolerance Induction (ITI) in Paediatric and Adult Patients with Haemophilia a (HA) and High-Titre (HT) Factor VIII (FVIII) Inhibitor - Real Life Data

Magdalena Katarzyna Letowska, Krystyna Zawilska, MD PhD, Anna Klukowska, MD PhD, Krzysztof Chojnowski, MD PhD, Joanna Zdziarska, MD PhD, Ewa Stefanska-Windyga, MD PhD, Jerzy Windyga

Blood (2019) 134 (Supplement_1): 4942.

https://doi.org/10.1182/blood-2019-122422

Published: 2019

Journal Articles

Immune Tolerance Induction (ITI) with a Plasma-Derived Factor VIII for Patients with Hemophilia a and Inhibitors: A Retrospective Study

Miguel A. Escobar, MD, Linda Shaffer, Mark Holguin, MD, Timothy McCavit, MD, Sandeep K. Rajan, MD, Novinyo Amega, MD

Blood (2019) 134 (Supplement_1): 4923.

https://doi.org/10.1182/blood-2019-122949

Published: 2019

Journal Articles

An IDO1 -Related 3-Gene Signature Predicts Overall Survival in Intermediate-Risk Acute Myeloid Leukemia

Simone Ragaini, MD, Sarah Wagner, BSc MSc, Giovanni Marconi, Sarah Parisi, MD PhD, Chiara Sartor, MD, Jacopo Nanni, MD, Gianluca Cristiano, Annalisa Talami, MD, Matteo Olivi, MD, Darina Ocadlikova, PhD, Marilena Ciciarello, PhD, Giulia Corradi, PhD, Emanuela Ottaviani, Cristina Papayannidis, Stefania Paolini, MD PhD, Jayakumar Vadakekolathu, PhD, Michele Cavo, Sergio Rutella, MD PhD FRCPath, Antonio Curti, MD PhD

Blood (2019) 134 (Supplement_1): 5193.

https://doi.org/10.1182/blood-2019-128348

Published: 2019

Journal Articles

Low Levels of Plasmacytoid Dendritic Cells at the Time of Engraftment Are a Valuable Severe aGVHD Indicator in Children Undergoing Allogeneic Stem Cell Transplantation

Bohan Li, Xinran Chu, Lijun Meng, PhD, Peifang Xiao, MD, Jie Li, MD, Jun Lu, MD, Yi Zhang, MD PhD, Shaoyan Hu, MD PhD

Blood (2019) 134 (Supplement_1): 3288.

https://doi.org/10.1182/blood-2019-128191

Published: 2019

Journal Articles

Low-Dose Immune Tolerance Induction for Hemophilia a Children with Poor-Risk High-Titer Inhibitors

Zekun Li, MBBS, Zhenping Chen, PhDMD, Xiaoling Cheng, Xinyi Wu, Li Gang, Zhen Yingzi, Cai Siyu, Man-Chiu Poon, Runhui Wu, MD PhD

Blood (2019) 134 (Supplement_1): 1122.

https://doi.org/10.1182/blood-2019-132021

Published: 2019

Journal Articles

Human Leukocyte Antigen-G Restores Immune Tolerance in Immune Thrombocytopenia

Qi Feng, Ji Ma, Xin Li, Ming Hou, Jun Peng, MD PhD

Blood (2018) 132 (Supplement 1): 3751.

https://doi.org/10.1182/blood-2018-99-115713

Published: 2018

Journal Articles

Treatment of Haemophilia a (HA) Patients with Inhibitors: Immune Tolerance Induction with a Single Factor VIII/Von Willebrand Factor Concentrate in an Observational Immune Tolerance Induction Study (ObsITI)

C. Escuriola Ettingshausen, Erik Berntorp, MD PhD, Yesim Dargaud, MD PhD, Zeynep Gutowski, PhD, Claude Negrier, Anna Pavlova, MD PhD, Johannes Oldenburg

Blood (2018) 132 (Supplement 1): 2482.

https://doi.org/10.1182/blood-2018-99-114408

Published: 2018

Journal Articles

Epigenetic Profile of Treg-like Cells Induced By Mesenchymal Stem Cells in Vitro Resembles That of Natural Treg

Rita I Azevedo, PhD, Ekaterina Minskaia, PhD, Cláudia Lobato da Silva, PhD, Ana Fernandes Platzgummer, PhD, Ana I.S. Vieira, MSc, Joaquim M.S. Cabral, PhD, Joao F Lacerda, MD PhD

Blood (2018) 132 (Supplement 1): 2578.

https://doi.org/10.1182/blood-2018-99-112452

Published: 2018

Journal Articles

Up-Regulation of Immune Tolerance Genes in Leukemic Mesenchymal Stromal Cells Is Induced By Acute Myeloid Leukemia Cells through an IFN-Gamma-Dependent Inflammatory Signaling

Marilena Ciciarello, PhD, Giulia Corradi, BS, Giorgia Simonetti, PhD, Giovanni Marconi, Sabina Sangaletti, PhD, Mario Paolo Colombo, Giovanni Martinelli, MD, Michele Cavo, MD, Antonio Curti

Blood (2018) 132 (Supplement 1): 2579.

https://doi.org/10.1182/blood-2018-99-112497

Published: 2018

Journal Articles

Outcome of Immune Tolerance Induction Using an Extended Half-Life Clotting Factor Concentrate — Recombinant Factor VIII Fc (Eloctate™) — a Report from India

Aby Abraham, MD DM, Shashikant Apte, MD FRCPA, Chandrakala Shamukhaiah, MD DM, Fouzia N., DNB, DM, Kannan Subramaniam, DNB, DM, Akshata Rahate, MD DM, Abraham Sunder Singh, BSc, Aditi Joshi, BAMS, Kavitha M Lakshmi, MSc, Rajesh Phatale, MD, Shrimati Shetty, PhD, Sukesh Chandran Nair, MD, Biju George, DM, Vikram Mathews, MD, Alok Srivastava, MD, FRACP,FRCPA

Blood (2018) 132 (Supplement 1): 2494.

https://doi.org/10.1182/blood-2018-99-119279

Published: 2018

Journal Articles

Real-World Data of Immune Tolerance Induction Using rFVIIIFc in Subjects With Severe Hemophilia A With Inhibitors at High Risk for ITI Failure

Manuel Carcao, Amy Shapiro, Nina Hwang, Steven Pipe, Sanjay Ahuja, Kenneth Lieuw, MD PhD, Janice Staber, Haowei Linda Sun, Hilda Ding, Michael Wang, Macgregor Steele, Elisa Tsao, Jing Feng, Zahra Al-Khateeb, Jennifer Dumont, Nisha Jain

Blood (2018) 132 (Supplement 1): 2500.

https://doi.org/10.1182/blood-2018-99-110467

Published: 2018

Journal Articles

Correlations of Plasma Cytokine Levels and Anti-FVIII Antibodies during Immune Tolerance Induction

Johannes Hartmann, MD, Anja Schmidt, PhD, Marko Beilfuss, Diana Stichel, Christine Heller, MD, Dirk Schwabe, MD, Thomas Klingebiel, MD, Nadia P Ewing, MD, Christoph Koenigs, MD PhD

Blood (2018) 132 (Supplement 1): 2471.

https://doi.org/10.1182/blood-2018-99-110588

Published: 2018

Journal Articles

Economic Impact of Immune Tolerance Induction (ITI) with Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) Compared to Conventional Recombinant Factor VIII (rFVIII)

Nanxin Li, Koo Wilson, Marc Botteman, MS, MA, Daniel Nicoloso, Sangeeta Krishnan, PharmD, Jun Su, MD

Blood (2018) 132 (Supplement 1): 3520.

https://doi.org/10.1182/blood-2018-99-114993

Published: 2018

Journal Articles

Successful of Immune Tolerance Induction (R-ITI) with Simoctocog Alfa (rhFVIII) in Hemophilia a Patients and High-Titer Inhibitors

Ezio Zanon, Samantha Pasca, Renato Marino, Angelo Claudio Molinari, MD

Blood (2018) 132 (Supplement 1): 5036.

https://doi.org/10.1182/blood-2018-99-114615

Published: 2018

Journal Articles

Immune Tolerance Induction with Simoctocog Alfa (Nuwiq ® ) in Six Patients with Severe Haemophilia a and FVIII Inhibitors

Neha Bhatnagar, ND, Kate Khair, Ri Liesner, Alice Wilkinson, Larisa Belyanskaya, PhD

Blood (2018) 132 (Supplement 1): 5037.

https://doi.org/10.1182/blood-2018-99-118041

Published: 2018

Journal Articles

A Novel Approach to Immune Tolerance Induction in Hemophilia Α with Factor VIII Inhibitor

Courtney D. Thornburg, MD, Jonathan M. Ducore, MD

Blood (2018) 132 (Supplement 1): 5042.

https://doi.org/10.1182/blood-2018-99-119800

Published: 2018

Journal Articles

Indoleamine 2,3-Dioxygenase-1 Expressing Dendritic Cell Populations Are Associated with Tumor-Induced Immune Tolerance & Aggressive Disease Biology in Chronic Myelomonocytic Leukemia

Blood (2018) 132 (Supplement 1): 4344.

https://doi.org/10.1182/blood-2018-99-113881

Published: 2018

Journal Articles

Induction of Donor-Specific Immune Tolerance with Clinical MIC Cell Infusion — a Phase I Study (TOL-1)

Christian Morath, MD, Anita Schmitt, MD, Christian Kleist, PhD, Volker Daniel, MD, Gerhard Opelz, MD, Caner Süsal, MD, Florian Kälble, MD, Claudia Sommerer, MD, Lei Wang, MD, Angela Hückelhoven, PhD, Arianeb Mehrabi, MD, Uta Merle, MD, Luiza Pego da Silva, Carsten Müller-Tidow, MD, Martin Zeier, MD, Matthias Schaier, MD, Michael Schmitt, MD PhD, Peter Terness, MD

Blood (2018) 132 (Supplement 1): 4539.

https://doi.org/10.1182/blood-2018-99-113386

Published: 2018

NARROW

FVIII Protein Is Not Detectable in Human PBMCs or Livers from Dogs with an Intron-22 Inversion Mutation: Implications for FVIII Immunogenicity and Tolerance

VCAM1 Confers Innate Immune Tolerance on Hematopoietic and Leukemic Stem Cells

Immune Tolerance Induction (ITI) in Paediatric and Adult Patients with Haemophilia a (HA) and High-Titre (HT) Factor VIII (FVIII) Inhibitor - Real Life Data

Immune Tolerance Induction (ITI) with a Plasma-Derived Factor VIII for Patients with Hemophilia a and Inhibitors: A Retrospective Study

An IDO1 -Related 3-Gene Signature Predicts Overall Survival in Intermediate-Risk Acute Myeloid Leukemia

Low Levels of Plasmacytoid Dendritic Cells at the Time of Engraftment Are a Valuable Severe aGVHD Indicator in Children Undergoing Allogeneic Stem Cell Transplantation

Low-Dose Immune Tolerance Induction for Hemophilia a Children with Poor-Risk High-Titer Inhibitors

Human Leukocyte Antigen-G Restores Immune Tolerance in Immune Thrombocytopenia

Treatment of Haemophilia a (HA) Patients with Inhibitors: Immune Tolerance Induction with a Single Factor VIII/Von Willebrand Factor Concentrate in an Observational Immune Tolerance Induction Study (ObsITI)

Epigenetic Profile of Treg-like Cells Induced By Mesenchymal Stem Cells in Vitro Resembles That of Natural Treg

Up-Regulation of Immune Tolerance Genes in Leukemic Mesenchymal Stromal Cells Is Induced By Acute Myeloid Leukemia Cells through an IFN-Gamma-Dependent Inflammatory Signaling

Outcome of Immune Tolerance Induction Using an Extended Half-Life Clotting Factor Concentrate — Recombinant Factor VIII Fc (Eloctate™) — a Report from India

Real-World Data of Immune Tolerance Induction Using rFVIIIFc in Subjects With Severe Hemophilia A With Inhibitors at High Risk for ITI Failure

Correlations of Plasma Cytokine Levels and Anti-FVIII Antibodies during Immune Tolerance Induction

Economic Impact of Immune Tolerance Induction (ITI) with Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) Compared to Conventional Recombinant Factor VIII (rFVIII)

Successful of Immune Tolerance Induction (R-ITI) with Simoctocog Alfa (rhFVIII) in Hemophilia a Patients and High-Titer Inhibitors

Immune Tolerance Induction with Simoctocog Alfa (Nuwiq ® ) in Six Patients with Severe Haemophilia a and FVIII Inhibitors

A Novel Approach to Immune Tolerance Induction in Hemophilia Α with Factor VIII Inhibitor

Indoleamine 2,3-Dioxygenase-1 Expressing Dendritic Cell Populations Are Associated with Tumor-Induced Immune Tolerance & Aggressive Disease Biology in Chronic Myelomonocytic Leukemia

Induction of Donor-Specific Immune Tolerance with Clinical MIC Cell Infusion — a Phase I Study (TOL-1)

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American Society of Hematology

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American Society of Hematology

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