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Journal Articles

The Novel Human Double Minute (HDM)-2 Inhibitor DS-5272 Is Active Both Alone, and In Combination With Other Novel Agents, Against Multiple Myeloma

Dongmin Gu, M.D., Ph.D., Hua Wang, Ph.D., Zhiqiang Wang, Ph.D., Richard E. Davis, M.D., Shengli Cai, M.D., Ph.D., Takahiko Seki, Ph.D., Archie Tse, M.D., Ph.D., Robert Z. Orlowski, M.D., Ph.D
Journal: Blood
Blood (2013) 122 (21): 1927.
https://doi.org/10.1182/blood.V122.21.1927.1927
Published: 2013
Journal Articles

Niche-Based Screening Identifies Novel Small Molecules That Overcome Stromal Effects in Multiple Myeloma

Shrikanta Chattopadhyay, MBBS, Alison L. Stewart, PhD, Siddhartha Mukherjee, MD, PhD, Cherrie Huang, Kimberly A. Hartwell, PhD, Peter G. Miller, PhD, Leigh Carmody, PhD, Rushdia Z. Yusuf, MBBS, MPH, David B. Sykes, MD, PhD, Sonia Vallet, Loredana Santo, Diana D. Cirstea, MD, Teru Hideshima, MD, PhD, Vladimir Dancik, PhD, Jaime Cheah, PhD, Edmund Price, Abigail Bracha, PhD, Max Majireck, PhD, Mahmud Hussain, PhD, Shambhavi Singh, Nicola Tolliday, PhD, Malcolm A.S. Moore, D.Phil, Andrew M. Stern, PhD, Alykhan F Shamji, PhD, Benjamin L. Ebert, MD, PhD, Todd R. Golub, MD, Noopur Raje, MD, David T. Scadden, MD, Stuart L. Schreiber, PhD
Journal: Blood
Blood (2012) 120 (21): 571.
https://doi.org/10.1182/blood.V120.21.571.571
Published: 2012
Journal Articles

A Phase I Study of the Kinesin Spindle Protein Inhibitor Ispinesib (SB-715992) in Relapsed/Refractory Acute Leukemia

Lisa M. Arfons, MD, Mark H. Kirschbaum, MD, Timothy W. Synold, PharmD, Hillard M. Lazarus, MD, Tamila L. Kindwall-Keller, DO, Mary J. Laughlin, MD, Maureen G. Conlan, MD, Joe Seroogy, Larry Doyle, Brenda W. Cooper, MD
Journal: Blood
Blood (2008) 112 (11): 4038.
https://doi.org/10.1182/blood.V112.11.4038.4038
Published: 2008
Journal Articles

Inhibition of Kinesin Spindle Protein Induces Apoptosis and Overcomes Drug Resistance in Models of Multiple Myeloma.

Qing Chen, PhD, Vishwan Pamarthi, Deborah J. Kuhn, PhD, Peter M. Voorhees, MD, John S. Strader, Robert Z. Orlowski, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 3425.
https://doi.org/10.1182/blood.V108.11.3425.3425
Published: 2006