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Journal Articles

Loss of the TLE4 AML Tumor Suppressor Gene Contributes to Leukemic Cell Proliferation, Differentiation Arrest, and Chemotherapy Resistance through a COX-Dependent Inflammatory Pathway

Thomas H Shin, David A Sweetser, MD,PhD

Blood (2015) 126 (23): 1241.

https://doi.org/10.1182/blood.V126.23.1241.1241

Published: 2015

Journal Articles

The Zinc Finger Transcription Factor Growth Factor Independence 1b (Gfi1b) Regulates The Wnt/Beta-Catenin Signaling Pathway In Hematopoietic Stem Cells Through Interaction With Inhibitory Proteins

Peiman Shooshtarizadeh, PhD, Ryan Chen, PhD, Tarik Moroy, Ph.D.

Blood (2013) 122 (21): 2417.

https://doi.org/10.1182/blood.V122.21.2417.2417

Published: 2013

Journal Articles

TLE1 Null Mice Have Altered Myeloid and B-Cell Differentiation As Well As Impaired Regulation of Inflammation

Selvi Ramasamy, PhD, Saez Borja, Ph.D, Subhankar Mukhopadhyay, Ph.D, Jianfeng Wang, M.D., Ph.D, Daching Ding, M.D., Ph.D, Xi Chen, M.D., Ph.D., David Sweetser, M.D., Ph.D.

Blood (2012) 120 (21): 1197.

https://doi.org/10.1182/blood.V120.21.1197.1197

Published: 2012

Journal Articles

Tle4 Is Critical for Proper B- Cell Differentiation and Maintenance of the Murine Bone Marrow Niche

Justin C Wheat, Jianfeng Wang, M.D., Ph.D., Xi Chen, M.D., Ph.D., Daniela S. Krause, M.D., Ph.D., David Sweetser, M.D., Ph.D.

Blood (2012) 120 (21): 1202.

https://doi.org/10.1182/blood.V120.21.1202.1202

Published: 2012

Journal Articles

The TLE1 Tumor Suppressor Regulates Myc Induced Leukemogenesis

David Sweetser, M.D., Ph.D., Selvi Ramasamy, PhD, Jessica S Blackburn, PhD, David M. Langenau, PhD

Blood (2011) 118 (21): 2473.

https://doi.org/10.1182/blood.V118.21.2473.2473

Published: 2011

Journal Articles

TLEs Regulate Myeloid Proliferation and Differentiation In Association with Modulation of NF-κB and Wnt Signaling

Jianfeng Wang, PhD, Farshid Dayyani, PhD, Christopher Brynzka, PhD, David Sweetser

Blood (2010) 116 (21): 4176.

https://doi.org/10.1182/blood.V116.21.4176.4176

Published: 2010

Journal Articles

Groucho/TLE Corepressors Regulate Myeloid Differentiation and Size of the Stem Cell/Progenitor Population.

Jianfeng Wang, MD, PhD, Farshid Dayyani, MD, PhD, Christopher Brynczka, David A. Sweetser, MD, PhD

Blood (2008) 112 (11): 1396.

https://doi.org/10.1182/blood.V112.11.1396.1396

Published: 2008

Journal Articles

Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival

Farshid Dayyani, Jianfeng Wang, Jing-Ruey J. Yeh, Eun-Young Ahn, Erica Tobey, Dong-Er Zhang, Irwin D. Bernstein, Randall T. Peterson, David A. Sweetser

Blood (2008) 111 (8): 4338–4347.

https://doi.org/10.1182/blood-2007-07-103291

Published: 2008

Includes: Supplemental data

Journal Articles

Role of the T-Cell Acute Lymphoblastic Leukemia Oncoprotein TLX1/HOX11 in Chromatin Dynamics and Gene Regulatory Networks.

Irene Riz, Kristin K. Baxter, Hyo Jung Lee, Reza Behnam, Teresa S. Hawley, Robert G. Hawley

Blood (2007) 110 (11): 56.

https://doi.org/10.1182/blood.V110.11.56.56

Published: 2007

Journal Articles

The Groucho Corepressors, TLE1 and TLE4 , Are Candidate Del(9q) AML Tumor Suppressor Genes That Can Complement AML1-ETO .

David A. Sweetser, MD, PhD, Farshid Dayyani, MD, Jianfeng Wang, MD, PhD, Yuntian Zhang, MS, Tanweer Zaidi, PhD

Blood (2006) 108 (11): 1406.

https://doi.org/10.1182/blood.V108.11.1406.1406

Published: 2006

Journal Articles

Characterization of NPM1 -Mutated/ FLT3 ITD-Negative Acute Myeloid Leukemia with Normal Karyotype by Gene Expression Profiling.

Lars Bullinger, MD, Konstanze Dohner, MD, Raphael Kranz, Frank G. Rucker, MD, Stefan Frohling, MD, Richard F. Schlenk, MD, Jonathan R. Pollack, MD, PhD, Hartmut Dohner, MD

Blood (2006) 108 (11): 155.

https://doi.org/10.1182/blood.V108.11.155.155

Published: 2006

Journal Articles

Premature Termination Codon Mutations in Chronic Lymphocytic Leukemia (CLL): Identification of Potential Tumor Suppressors in CLL Including E-Cadherin.

Sanjai Sharma, MD, Alan Lichtenstein, MD

Blood (2005) 106 (11): 2935.

https://doi.org/10.1182/blood.V106.11.2935.2935

Published: 2005

Journal Articles

TLE Corepressors as Novel Candidate AML Tumor Suppressor Genes That Regulate Wnt Signaling, Cell Cycle Progression, and Myeloid Differentiation.

Farshid Dayyani, MD, Yuntian Zhang, MS, Sayyed T. Zaidi, PhD, David A. Sweetser, MD, PhD

Blood (2005) 106 (11): 1601.

https://doi.org/10.1182/blood.V106.11.1601.1601

Published: 2005

NARROW

Loss of the TLE4 AML Tumor Suppressor Gene Contributes to Leukemic Cell Proliferation, Differentiation Arrest, and Chemotherapy Resistance through a COX-Dependent Inflammatory Pathway

The Zinc Finger Transcription Factor Growth Factor Independence 1b (Gfi1b) Regulates The Wnt/Beta-Catenin Signaling Pathway In Hematopoietic Stem Cells Through Interaction With Inhibitory Proteins

TLE1 Null Mice Have Altered Myeloid and B-Cell Differentiation As Well As Impaired Regulation of Inflammation

Tle4 Is Critical for Proper B- Cell Differentiation and Maintenance of the Murine Bone Marrow Niche

The TLE1 Tumor Suppressor Regulates Myc Induced Leukemogenesis

TLEs Regulate Myeloid Proliferation and Differentiation In Association with Modulation of NF-κB and Wnt Signaling

Groucho/TLE Corepressors Regulate Myeloid Differentiation and Size of the Stem Cell/Progenitor Population.

Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival

Role of the T-Cell Acute Lymphoblastic Leukemia Oncoprotein TLX1/HOX11 in Chromatin Dynamics and Gene Regulatory Networks.

The Groucho Corepressors, TLE1 and TLE4 , Are Candidate Del(9q) AML Tumor Suppressor Genes That Can Complement AML1-ETO .

Characterization of NPM1 -Mutated/ FLT3 ITD-Negative Acute Myeloid Leukemia with Normal Karyotype by Gene Expression Profiling.

Premature Termination Codon Mutations in Chronic Lymphocytic Leukemia (CLL): Identification of Potential Tumor Suppressors in CLL Including E-Cadherin.

TLE Corepressors as Novel Candidate AML Tumor Suppressor Genes That Regulate Wnt Signaling, Cell Cycle Progression, and Myeloid Differentiation.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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