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Journal Articles

Idarucizumab, a Specific Antidote for Dabigatran, Cross-Reacts with Melagatran and May Also Interact with Other Benzamidine-Containing Compounds

Jawed Fareed, PhD, Larissa Reikensmeyer, Amanda Walborn, BS, Debra Hoppensteadt, PhD, Jeanine M. Walenga, PhD, Eduardo Ramacciotti, MD, Schuharazad Abro, MD, Walter Jeske, PhD, Olivia Bouchard, Ismail Elalamy, MD PhD

Blood (2016) 128 (22): 3836.

https://doi.org/10.1182/blood.V128.22.3836.3836

Published: 2016

Journal Articles

Oral Anti-Factor Xa and Factor IIa Agent Mediated Inhibition Of Tissue-Factor Mediated Generation Of Thrombin In Prothrombin Complex Concentrates

Daneyal Syed, Debra Hoppensteadt, Ph.D., Daniel Kahn, Job Harenberg, Prof.,, Jawed Fareed, Ph.D.

Blood (2013) 122 (21): 4810.

https://doi.org/10.1182/blood.V122.21.4810.4810

Published: 2013

Journal Articles

Thrombin Generation Inhibition by Newer Anti Xa and Anti IIa Drugs in Prothrombin Complex Concentrates: Relevance to Endogenous Modulation of Thrombogenesis

Angel Gray, Evangelos Litinas, MD, Debra Hoppensteadt, Ph.D., Josephine Cunanan, MD, Bruce E Lewis, MD, Omer Iqbal, MD, Jawed Fareed, PhD

Blood (2011) 118 (21): 1196.

https://doi.org/10.1182/blood.V118.21.1196.1196

Published: 2011

Journal Articles

Differential Effects of TAK-442, a Factor Xa Inhibitor, and Ximelagatran, a Thrombin Inhibitor, on Bleeding: Possible Role of Differences in Effects on Factor V-Mediated Feedback on Blood Coagulation Cascade

Noriko Konishi, Katsuhiko Hiroe, Yasuhiro Imaeda, Takuya Fujimoto, Keiji Kubo, PhD, Masaki Kawamura, DVM, PhD

Blood (2008) 112 (11): 5460.

https://doi.org/10.1182/blood.V112.11.5460.5460

Published: 2008

Journal Articles

Direct Thrombin Inhibitors, but Not Factor Xa Inhibitors, Enhance Thrombin Formation in Human Plasma by Interfering with the Thrombin–Thrombomodulin–Protein C System

Elisabeth Perzborn, PhD, Michaela Harwardt

Blood (2008) 112 (11): 528.

https://doi.org/10.1182/blood.V112.11.528.528

Published: 2008

Journal Articles

Effects of Direct Factor Xa Inhibitor, YM150, on Clot Formation and Clot Lysis In Vitro Compared with Other Anticoagulants.

Seiji Kaku, PhD, Ken-ichi Suzuki, Ph.D, Toshiyuki Funatsu, Ph.D, Minori Saitoh, Ph.D, Hiroyuki Koshio, Ph.D, Tsukasa Ishihara, Ph.D, Fukushi Hirayama, Ph.D, Tomihisa Kawasaki, D.V.M., Ph.D.

Blood (2007) 110 (11): 3153.

https://doi.org/10.1182/blood.V110.11.3153.3153

Published: 2007

Journal Articles

The Effect of Irreversible and Reversible Direct Thrombin Inhibitors and Danaparoid on Tissue Factor Mediated Thrombin Generation.

Meyer M. Samama, Lena Le Flem, Daphne Pierre-Eugène, Francois Depasse

Blood (2006) 108 (11): 4111.

https://doi.org/10.1182/blood.V108.11.4111.4111

Published: 2006

Journal Articles

Antithrombin-Independent Thrombin Inhibitors, but Not Factor Xa Inhibitors, Enhance Thrombin Generation in Human Plasma Via Inhibition of Thrombin-Thrombomodulin-Protein C System.

Yoshiyuki Morishima, PhD, Taketoshi Furugohri, Yoko Shiozaki, Nobutoshi Sugiyama, PhD, Toshiro Shibano, PhD

Blood (2006) 108 (11): 914.

https://doi.org/10.1182/blood.V108.11.914.914

Published: 2006

Journal Articles

Prevalence of Aspirin Non-Response in Out-Patients and In-Patients as Determined by Multiple Electrode Aggregometry.

Andreas Calatzis, MD, Klaus-Werner von Pape, Armin J. Reininger, MD, Franz Theisen, MD, Michael Spannagl, MD

Blood (2006) 108 (11): 879.

https://doi.org/10.1182/blood.V108.11.879.879

Published: 2006

Journal Articles

Monitoring of Clopidogrel Using Multiple Electrode Aggregometry.

Andreas Calatzis, MD, Franz Theisen, MD, Armin J. Reininger, MD, Michael Spannagl, MD

Blood (2006) 108 (11): 883.

https://doi.org/10.1182/blood.V108.11.883.883

Published: 2006

Journal Articles

A Thrombin Inhibitor, but Not a Factor Xa Inhibitor, DU-176b, Aggravates Tissue Factor-Induced Hypercoagulation in Rats.

Yoshiyuki Morishima, PhD, Toshio Fukuda, Naoki Tsuji, PhD, Yuko Honda, Chikako Matsumoto, Taketoshi Furugohri, Toshiro Shibano, PhD

Blood (2005) 106 (11): 1878.

https://doi.org/10.1182/blood.V106.11.1878.1878

Published: 2005

Journal Articles

The Oral, Direct Factor Xa Inhibitor BAY 59-7939 Does Not Cross-React with Anti-Heparin/PF4 (Heparin-Induced Thrombocytopenia) Antibodies.

Jeanine M. Walenga, PhD, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Brian Neville, PhD, Walter P. Jeske, PhD, Margaret Prechel, PhD, Harry L. Messmore, PhD, Frank Misselwitz, MD, PhD, Mamdouh Bakhos, PhD

Blood (2005) 106 (11): 1883.

https://doi.org/10.1182/blood.V106.11.1883.1883

Published: 2005

Journal Articles

Relative Inhibition of Thrombin Activatable Fibrinolytic Inhibitor by Newly Developed Thrombin Inhibitors: Impact on Bleeding and Antithrombotic Actions.

Michelle R. Florian-Kujawski, BS(H), Debra Hoppensteadt, PhD, Josephine Cunanan, MD, Marianne Wilmer, PhD, Jawed Fareed, PhD

Blood (2005) 106 (11): 4051.

https://doi.org/10.1182/blood.V106.11.4051.4051

Published: 2005

Journal Articles

Ximelagatran in Major Orthopedic Surgery: A Systematic Review and Meta-Analysis of Efficacy and Safety.

Alejandro Lazo-Langner, MD, Marc A. Rodger, MD, MSc, Philip S. Wells, MD, MSc

Blood (2005) 106 (11): 913.

https://doi.org/10.1182/blood.V106.11.913.913

Published: 2005

Journal Articles

Melagatran and Dynamic Whole Blood Clot Formation - Haemostatic Response to Ex Vivo Recombinant Factor Viia and Activated Prothrombin Complex Concentrate.

Benny Sorensen, MD, Ph.D., Margareta Elg, MD, Ph.D., Stefan Carlsson, MD, Ph.D., Jorgen Ingerslev, MD, DMSc

Blood (2004) 104 (11): 1857.

https://doi.org/10.1182/blood.V104.11.1857.1857

Published: 2004

Journal Articles

Comparison of the Anticoagulant Effect of Melagatran and Lmwh in an Acquired Antithrombin Deficiency in Children with All Treated with L-Asparaginase.

Lesley G. Mitchell, MSc, Stefan Kuhle, MD, Patrica Vegh, Alice Lau, BSc

Blood (2004) 104 (11): 1860.

https://doi.org/10.1182/blood.V104.11.1860.1860

Published: 2004

NARROW

Idarucizumab, a Specific Antidote for Dabigatran, Cross-Reacts with Melagatran and May Also Interact with Other Benzamidine-Containing Compounds

Oral Anti-Factor Xa and Factor IIa Agent Mediated Inhibition Of Tissue-Factor Mediated Generation Of Thrombin In Prothrombin Complex Concentrates

Thrombin Generation Inhibition by Newer Anti Xa and Anti IIa Drugs in Prothrombin Complex Concentrates: Relevance to Endogenous Modulation of Thrombogenesis

Differential Effects of TAK-442, a Factor Xa Inhibitor, and Ximelagatran, a Thrombin Inhibitor, on Bleeding: Possible Role of Differences in Effects on Factor V-Mediated Feedback on Blood Coagulation Cascade

Direct Thrombin Inhibitors, but Not Factor Xa Inhibitors, Enhance Thrombin Formation in Human Plasma by Interfering with the Thrombin–Thrombomodulin–Protein C System

Effects of Direct Factor Xa Inhibitor, YM150, on Clot Formation and Clot Lysis In Vitro Compared with Other Anticoagulants.

The Effect of Irreversible and Reversible Direct Thrombin Inhibitors and Danaparoid on Tissue Factor Mediated Thrombin Generation.

Antithrombin-Independent Thrombin Inhibitors, but Not Factor Xa Inhibitors, Enhance Thrombin Generation in Human Plasma Via Inhibition of Thrombin-Thrombomodulin-Protein C System.

Prevalence of Aspirin Non-Response in Out-Patients and In-Patients as Determined by Multiple Electrode Aggregometry.

Monitoring of Clopidogrel Using Multiple Electrode Aggregometry.

A Thrombin Inhibitor, but Not a Factor Xa Inhibitor, DU-176b, Aggravates Tissue Factor-Induced Hypercoagulation in Rats.

The Oral, Direct Factor Xa Inhibitor BAY 59-7939 Does Not Cross-React with Anti-Heparin/PF4 (Heparin-Induced Thrombocytopenia) Antibodies.

Relative Inhibition of Thrombin Activatable Fibrinolytic Inhibitor by Newly Developed Thrombin Inhibitors: Impact on Bleeding and Antithrombotic Actions.

Ximelagatran in Major Orthopedic Surgery: A Systematic Review and Meta-Analysis of Efficacy and Safety.

Melagatran and Dynamic Whole Blood Clot Formation - Haemostatic Response to Ex Vivo Recombinant Factor Viia and Activated Prothrombin Complex Concentrate.

Comparison of the Anticoagulant Effect of Melagatran and Lmwh in an Acquired Antithrombin Deficiency in Children with All Treated with L-Asparaginase.

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American Society of Hematology

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American Society of Hematology

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