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Journal Articles

Targeting Glycolysis in Multiple Myeloma: Novel Strategies in the Treatment of Proteasome Inhibitor Resistant in Hypoxic Conditions

Seiichi Okabe, MD PhD, Yuko Tanaka, MD PhD, Mitsuru Moriyama, Akihiko Gotoh, MD PhD

Blood (2019) 134 (Supplement_1): 4344.

https://doi.org/10.1182/blood-2019-129818

Published: 2019

Journal Articles

IGF1R-IRS1/2 Signaling Pathway Is a Potential Target for FLT3-Mutated Acute Myeloid Leukemia

Juan L Coelho-Silva, BSc, MSc, Diego A Pereira-Martins, MSc, Virginia Campos Silvestrini, BSc, MSc, Eduardo M Rego, MD PhD, Vitor Marcel Faca, PhD, João Agostinho Machado-Neto, PhD, Fabiola Traina, MD PhD

Blood (2019) 134 (Supplement_1): 2689.

https://doi.org/10.1182/blood-2019-132129

Published: 2019

Journal Articles

The Sequenced Combination of Rigosertib and Azacitidine Has Modulatory Effects on CXCL8, RIG-I like Receptor (RLR) and Wnt/β-Catenin Signaling and Downstream Hematopoiesis Pathways in an in Vitro Model of the Myelodysplastic Syndrome

Richa Rai, PhD, Stella Melana, PhD, Shyamala C. Navada, MD, Rosalie Odchimar-Reissig, RN, Erin P. Demakos, RN, E. Premkumar Reddy, PhD, Lewis R. Silverman, MD

Blood (2019) 134 (Supplement_1): 4231.

https://doi.org/10.1182/blood-2019-130747

Published: 2019

Journal Articles

KLF4 Is Needed for Optimal Hydroxyurea Induction of Gamma-Globin in K562 Cells

Alireza Paikari, MD, Ankush Goyal, MA, Celeste K. Kanne, BA, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 971.

https://doi.org/10.1182/blood-2019-131214

Published: 2019

Journal Articles

P38α/JNK Signaling Restrains Erythropoiesis By Suppressing Ezh2-Mediated Epigenetic Silencing of Bim

Ping Hu, MD PhD, Angel Nebreda, PhD, Helmut Hanenberg, MD, Garrett Kinnebrew, MD, Mircea Ivan, MD PhD, Mervin C. Yoder, MD, Marie-Dominique Filippi, PhD, Hal E. Broxmeyer, PhD, Reuben Kapur, PhD

Blood (2018) 132 (Supplement 1): 3837.

https://doi.org/10.1182/blood-2018-99-117098

Published: 2018

Journal Articles

Nitric Oxide Mediates Downregulation of Tissue Factor Expression in Primary Human Pericytes through a p38 MAPK Signaling Pathway

Laura Sommerville, PhD, Maureane Hoffman, MD

Blood (2018) 132 (Supplement 1): 2425.

https://doi.org/10.1182/blood-2018-99-119192

Published: 2018

Journal Articles

PI3Kinase Alpha and Delta Promote Hematopoietic Stem Activation Under Stress

Shayda Hemmati, PhD, Taneisha Sinclair, Meng Tong, Boris Bartholdy, PhD, Rachel Okabe, MD, Kristina Ames, PhD, Leanne Ostrodka, MD, Tamanna Haque, MD, Imit Kaur, PhD, Anupriya Agarwal, PhD, Jean Zhao, PhD, Thomas Roberts, PhD, Kira Gritsman, MD PhD

Blood (2018) 132 (Supplement 1): 329.

https://doi.org/10.1182/blood-2018-99-114891

Published: 2018

Journal Articles

The Role of LAMP5 in Innate Immune Signaling Is Critical for the Survival of MLL Leukemias

Gabriel Gracia-Maldonado, BS, Jason Clark, MS, Philippe Pierre, PhD, James C. Mulloy, PhD, Ashish R Kumar, MD PhD

Blood (2018) 132 (Supplement 1): 3900.

https://doi.org/10.1182/blood-2018-99-120190

Published: 2018

Journal Articles

Three Different Jak2/Stat3-Related Pathways Favor the Survival of Chronic Lymphocytic Leukemia Neoplastic Clone

Filippo Severin, PhD MSc, Federica Frezzato, PhD, Veronica Martini, PhD MSc, Flavia Raggi, Valentina Trimarco, Andrea Visentin, Monica Facco, Gianpietro Semenzato, Livio Trentin, MD

Blood (2018) 132 (Supplement 1): 4405.

https://doi.org/10.1182/blood-2018-99-114591

Published: 2018

Journal Articles

Targeting Central Mechanisms of Pain to Improve Acupuncture Analgesia in a Humanized Mouse Model of Sickle Cell Disease

Ying Wang, MD PhD, Jianxun Lei, PhD, Kalpna Gupta, PhD

Blood (2018) 132 (Supplement 1): 1064.

https://doi.org/10.1182/blood-2018-99-115577

Published: 2018

Journal Articles

Synergistic Dual Inhibition of BCR-ABL1 and the Unfolded Protein Response Causes p38 MAPK-Mediated Cell Death and Sensitizes BCR-ABL1 + Acute Lymphoblastic Leukemia to Dexamethasone

Margherita Vieri, MSc, Christian Preisinger, Mirle Schemionek, Azam Salimi, John B. Patterson, Afshin Samali, Tim H Brümmendorf, MD, Iris Appelmann, MD, Behzad Kharabi Masouleh, MD

Blood (2018) 132 (Supplement 1): 4674.

https://doi.org/10.1182/blood-2018-99-110967

Published: 2018

Journal Articles

Sinusoidal Obstruction Syndrom (SOS): Warning about Autologous Stem Cell Transplantation (ASCT) Preceded By Regimens Containing Oxaliplatin

Pierre-Edouard Debureaux, Delphine Le Febvre de Nailly, Emmanuelle Tavernier, MD, Manel Bedoui, MD, Frederique Kuhnowski, MD, Jerome Tamburini, MD PhD, Luc Mathieu Fornecker, Herve Tilly, MD, David Sibon, MD PhD, Marie-Pierre Moles, Sylvie Glaisner, MD, Jean Philippe Richardet, MD PhD, Sebastien Mule, MD PhD, Julien Calderaro, MD, Corinne Haioun, MD, Jehan Dupuis, MD

Blood (2018) 132 (Supplement 1): 4597.

https://doi.org/10.1182/blood-2018-99-110728

Published: 2018

Journal Articles

Rafoxanide, an Organohalogen Drug, Triggers Apoptosis and Cell Cycle Arrest in Multiple Myeloma By Enhancing DNA Damage Responses and Suppressing the p38 MAPK Pathway

Jumei Shi, Wenqin Xiao, Zhijian Xu, Shuaikang Chang, Lu Gao, Yi Tao, Yingcong Wang, Xiaosong Wu, Weiliang Zhu

Blood (2018) 132 (Supplement 1): 5628.

https://doi.org/10.1182/blood-2018-99-113782

Published: 2018

Journal Articles

Sequential Treatment with Rigosertib Followed By Azacitidine Maximizes the Effects on the Interferon Signaling Pathway in Hematopoietic Cells in Myelodysplastic Syndrome (MDS)

Richa Rai, PhD, Stella Melana, PhD, Shyamala C. Navada, MD, Rosalie Odchimar-Reissig, RN, Erin P. Demakos, RN, E. Premkumar Reddy, PhD, Lewis R. Silverman, MD

Blood (2018) 132 (Supplement 1): 5500.

https://doi.org/10.1182/blood-2018-99-119266

Published: 2018

Journal Articles

Targeting Elastase with Alpha1 Anti-Trypsin Reduces Hyperalgesia in Mice with Sickle Cell Disease

Aithanh Nguyen, Sophia Pantano, Waogwende Leonce Song-Naba, BS, Ritu Jha, MSc, Julia Nguyen, BS, Kalpna Gupta, PhD

Blood (2018) 132 (Supplement 1): 724.

https://doi.org/10.1182/blood-2018-99-111872

Published: 2018

Journal Articles

Aberrant Cytokine Production in Myelofibrosis Is Not Rectified By Ruxolitinib and Is Differentially Sensitive to Inhibition of JAK/STAT, MAP Kinase, and NFκB Signaling

Daniel A.C. Fisher, PhD, Cathrine Miner, Elizabeth Engle, PhD, Hengrui Hu, Taylor B. Collins, Amy Zhou, MD, Maggie J. Allen, Olga Malkova, Stephen T Oh, MD PhD

Blood (2018) 132 (Supplement 1): 3062.

https://doi.org/10.1182/blood-2018-99-119022

Published: 2018

Journal Articles

The Role and Mechanism of Upregulation of HO-1 Expression By Activating of Adenosine-2a Receptor in the Tumor Immune Microenvironment with Diffuse Large B-Cell Lymphoma

Chanjuan Wang, Jishi Wang, PhD

Blood (2018) 132 (Supplement 1): 2948.

https://doi.org/10.1182/blood-2018-99-117967

Published: 2018

Journal Articles

RNAi Screens for Maintenance of Hematopoietic Stem Cell Phenotype During Culture

Jonas Larsson, MD PhD

Blood (2017) 130 (Supplement 1): SCI-45.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-45.SCI-45

Published: 2017

Journal Articles

Atorvastatin May Reverse Corticosteroid-Resistant Immune Thrombocytopenia Via Improving Impaired Bone Marrow Endothelial Cells

Yuan Kong, Xie-Na Cao, Xiaohui Zhang, MD, Min-Min Shi, Yue-Yun Lai, Yu Wang, Lan-Ping Xu, Ying-Jun Chang, Xiao-Jun Huang, MD

Blood (2017) 130 (Supplement 1): 232.

https://doi.org/10.1182/blood.V130.Suppl_1.232.232

Published: 2017

Journal Articles

p38 MAPK and NF-κB Survival Pathways As Targets for Action of Rituximab In Vivo in a Xenographic Model,

Gabriel G Vega, PhD, Monica Arteaga-Campos, Bch, Melisa Martinez-Paniagua, PhD, Natividad Neri Munoz, PhD MD, M. J Nambo, Isabel Alvarado, Ivonne Cuadra, MD, Sara Huerta-Yepez, PhD, Mario Vega, PhD

Blood (2017) 130 (Supplement 1): 5199.

https://doi.org/10.1182/blood.V130.Suppl_1.5199.5199

Published: 2017

NARROW

Targeting Glycolysis in Multiple Myeloma: Novel Strategies in the Treatment of Proteasome Inhibitor Resistant in Hypoxic Conditions

IGF1R-IRS1/2 Signaling Pathway Is a Potential Target for FLT3-Mutated Acute Myeloid Leukemia

The Sequenced Combination of Rigosertib and Azacitidine Has Modulatory Effects on CXCL8, RIG-I like Receptor (RLR) and Wnt/β-Catenin Signaling and Downstream Hematopoiesis Pathways in an in Vitro Model of the Myelodysplastic Syndrome

KLF4 Is Needed for Optimal Hydroxyurea Induction of Gamma-Globin in K562 Cells

P38α/JNK Signaling Restrains Erythropoiesis By Suppressing Ezh2-Mediated Epigenetic Silencing of Bim

Nitric Oxide Mediates Downregulation of Tissue Factor Expression in Primary Human Pericytes through a p38 MAPK Signaling Pathway

PI3Kinase Alpha and Delta Promote Hematopoietic Stem Activation Under Stress

The Role of LAMP5 in Innate Immune Signaling Is Critical for the Survival of MLL Leukemias

Three Different Jak2/Stat3-Related Pathways Favor the Survival of Chronic Lymphocytic Leukemia Neoplastic Clone

Targeting Central Mechanisms of Pain to Improve Acupuncture Analgesia in a Humanized Mouse Model of Sickle Cell Disease

Synergistic Dual Inhibition of BCR-ABL1 and the Unfolded Protein Response Causes p38 MAPK-Mediated Cell Death and Sensitizes BCR-ABL1 + Acute Lymphoblastic Leukemia to Dexamethasone

Sinusoidal Obstruction Syndrom (SOS): Warning about Autologous Stem Cell Transplantation (ASCT) Preceded By Regimens Containing Oxaliplatin

Rafoxanide, an Organohalogen Drug, Triggers Apoptosis and Cell Cycle Arrest in Multiple Myeloma By Enhancing DNA Damage Responses and Suppressing the p38 MAPK Pathway

Sequential Treatment with Rigosertib Followed By Azacitidine Maximizes the Effects on the Interferon Signaling Pathway in Hematopoietic Cells in Myelodysplastic Syndrome (MDS)

Targeting Elastase with Alpha1 Anti-Trypsin Reduces Hyperalgesia in Mice with Sickle Cell Disease

Aberrant Cytokine Production in Myelofibrosis Is Not Rectified By Ruxolitinib and Is Differentially Sensitive to Inhibition of JAK/STAT, MAP Kinase, and NFκB Signaling

The Role and Mechanism of Upregulation of HO-1 Expression By Activating of Adenosine-2a Receptor in the Tumor Immune Microenvironment with Diffuse Large B-Cell Lymphoma

RNAi Screens for Maintenance of Hematopoietic Stem Cell Phenotype During Culture

Atorvastatin May Reverse Corticosteroid-Resistant Immune Thrombocytopenia Via Improving Impaired Bone Marrow Endothelial Cells

p38 MAPK and NF-κB Survival Pathways As Targets for Action of Rituximab In Vivo in a Xenographic Model,

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American Society of Hematology

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ASH Publications

American Society of Hematology

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