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Journal Articles

Epigenetic Activation of the pH Regulator MCT4 in Acute Myeloid Leukemia Exploits a Fundamental Metabolic Process of Enhancing Cell Growth through Proton Shifting

Cheuk-Him Man, David T. Scadden, MD, Francois Mercier, MD FRCPC, Nian Liu, Wentao Dong, Gregory Stephanopoulos, PhD, Li Jiang, PhD, Yookyung Jung, PhD, Charles Lin, PhD, Anskar Y.-H. Leung, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3765.
https://doi.org/10.1182/blood-2019-123604
Published: 2019
Journal Articles

Cereblon and Redox in Plasma Cells

Florian Bassermann, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): SCI-9.
https://doi.org/10.1182/blood.V130.Suppl_1.SCI-9.SCI-9
Published: 2017
Journal Articles

Preliminary Data Show Heterogenous Patterns of 18 f-FDG PET/CT When Assessing the Inflammatory Component of Primary or Secondary Myelofibrosis

Mario Ojeda-Uribe, Christophe Schohn, MD, Olivier Morel, MD, Nathalie Mac Dougall, MD, Xavier Malezieux, MD, Atteka Chabanse, PharmD, Andrien Norosoa, MD, Laurent Mauvieux, MD PhD, Hatem Boulahdour, MD PhD, Edmond Rust, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5280.
https://doi.org/10.1182/blood.V130.Suppl_1.5280.5280
Published: 2017
Journal Articles

L-Asparaginase More Effectively Targets Leukemic Cells with Low Glycolytic Activity

Simcikova Marketa, Alena Pecinova, Ivana Hermanova, David Pajuelo Reguera, Katerina Rejlova, Marketa Zaliova, Jan Stuchly, Tomas Mracek, Jan Trka, Julia Starkova
Journal: Blood
Blood (2015) 126 (23): 1285.
https://doi.org/10.1182/blood.V126.23.1285.1285
Published: 2015
Journal Articles

Metabolic Patterns in Cancer Cells and Tumor Microenvironment in Diffuse Large B-Cell Lymphoma: Tumor-Stromal Metabolic Coupling

Mahasweta Gooptu, MD, Alina E Dulau Florea, MD, Benjamin E Leiby, PhD, Barbara Pro, John David Sprandio, Jr., MD, Diana whittaker-Menezes, Paolo Cotzia, MD, Guldeep Uppal, MD, Jaime Caro, MD, Jerald Gong, MD, Ubaldo Martinez-Outschoorn, MD
Journal: Blood
Blood (2015) 126 (23): 3892.
https://doi.org/10.1182/blood.V126.23.3892.3892
Published: 2015
Journal Articles

The Effect of Prophylactic Recombinant Factor IX and Glycopegylated Factor IX to Normalize Articular Wound Healing Following Hemarthrosis Examined in Hemophilia B Mice

Junjiang Sun, MD, Eric Livingston, Tom Knudsen, DVM, PhD, Dougald M. Monroe, III, PhD, Mirella Ezban, PhD, Ted Bateman, PhD, Paul E. Monahan, MD
Journal: Blood
Blood (2015) 126 (23): 549.
https://doi.org/10.1182/blood.V126.23.549.549
Published: 2015
Journal Articles

Metabolic Reprogramming of Bone Marrow Stromal Cells By Leukemic Extracellular Vesicles in Acute Lymphoblastic Leukemia (ALL)

Suzanne M. Johnson, Clare Dempsey, Amy Chadwick, Stephanie Harrison, Jizhong Liu, Yujun Di, Owen McGinn, Mayur Parihar, Federica Sotgia, Michael Lisanti, Shekhar Krishnan, Vaskar Saha, PhD FRCP, FRCPath
Journal: Blood
Blood (2015) 126 (23): 1430.
https://doi.org/10.1182/blood.V126.23.1430.1430
Published: 2015
Journal Articles

Prognostic Factors for Overall Survival in Relapsed Acute Myeloid Leukemia

Thomas Heinicke, MD, Rainer Krahl, PhD, Christoph Kahl, MD, Sebastian Scholl, MD, Hans-Heinrich Wolf, MD, Detlev Hähling, MD, Ute Hegenbart, MD, Norma Peter, MD, Antje Schulze, MD, Axel Florschütz, MD, Kolja Reifenrath, Niklas Zojer, MD, Christian Jakob, MD, Christian Junghanss, MD, Herbert G. Sayer, MD PhD, Georg Maschmeyer, MD, Andreas Hochhaus, MD, Thomas Fischer, MD, Dietger Niederwieser, MD, Haifa Kathrin Al-Ali, MD
Journal: Blood
Blood (2014) 124 (21): 3666.
https://doi.org/10.1182/blood.V124.21.3666.3666
Published: 2014
Journal Articles

Hodgkin Lymphoma: Metabolic Symbiosis Between Malignant Cells and Cancer-Associated Stromal Tissue

John D Sprandio, Jr., MD, Alina E. Dulau Florea, MD, Ubaldo Martinez-Outschoorn, MD
Journal: Blood
Blood (2013) 122 (21): 2993.
https://doi.org/10.1182/blood.V122.21.2993.2993
Published: 2013
Journal Articles

MLN9708 Elicits Pharmacodynamic Response in the Bone Marrow Compartment and Has Strong Antitumor Activity in a Preclinical Intraosseous Model of Plasma Cell Malignancy.

Edmund Lee, Bret Bannerman, Michael Fitzgerald, Jennifer Terkelsen, Daniel Bradley, Zhi Li, Ping Li, Siegfried Janz, Brian G Van Ness, Mark Manfredi, Erik Kupperman
Journal: Blood
Blood (2009) 114 (22): 1834.
https://doi.org/10.1182/blood.V114.22.1834.1834
Published: 2009
Journal Articles

Evaluating the Antitumor Activity of MLN9708 in a Disseminated Mouse Model of Double Transgenic iMyc Ca /Bcl-X L Plasma Cell Malignancy.

Michael Fitzgerald, Yueying Cao, Bret Bannerman, Zhi Li, Olga Tayber, Ping Li, Jennifer Terkelsen, Daniel Bradley, Jonathan Frazer, Lee Silverman, PhD, Siegfried Janz, Brian G Van Ness, Erik Kupperman, Mark Manfredi, Edmund Lee
Journal: Blood
Blood (2009) 114 (22): 3835.
https://doi.org/10.1182/blood.V114.22.3835.3835
Published: 2009
Journal Articles

The Novel Proteasome Inhibitor MLN9708 Demonstrates Efficacy in a Genetically-Engineered Mouse Model of DeNovo Plasma Cell Malignancy.

Siegfried Janz, Brian G Van Ness, Vishala Neppalli, Ray Liu, Michael D Pickard, Jennifer Terkelsen, Daniel Bradley, Ling Hu, Erik Kupperman, Mark Manfredi, Edmund Lee
Journal: Blood
Blood (2009) 114 (22): 3849.
https://doi.org/10.1182/blood.V114.22.3849.3849
Published: 2009
Journal Articles

Effects of Age on the Development of Arthropathy in Mice with Hemophilia.

Leonard A. Valentino, MD, FAAP, Narine Hakobyan, PhD, D. Rick Sumner, PhD, Candace Enockson
Journal: Blood
Blood (2008) 112 (11): 3393.
https://doi.org/10.1182/blood.V112.11.3393.3393
Published: 2008
Journal Articles

Molecular Pathways of Response to Recombinant Human Erythropoietin (rHuEpo) in Myelodysplastic patients Assayed with Macroarrays.

Cortelezzi Agostino, MD, Colombo Gualtiero, MD, Pellegrini Caterina, Biol Sci, Silvestris Ilaria, Bosari Silvano, MD, Lambertenghi Deliliers Giorgio, MD, Fracchiolla S. Nicola, MD
Journal: Blood
Blood (2004) 104 (11): 2367.
https://doi.org/10.1182/blood.V104.11.2367.2367
Published: 2004