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Journal Articles

Comparative Evaluation of Complement Factor D, C3, and C5 Inhibitors on Serum Bactericidal Activity Against Neisseria Meningitidis Isolates

Yongsen Zhao, Dharaben Patel, MS, Jane A Thanassi, BS, Mingjun Huang, PhD, Steven D Podos, PhD

Blood (2019) 134 (Supplement_1): 5763.

https://doi.org/10.1182/blood-2019-132253

Published: 2019

Journal Articles

No Demonstrable Benefit of Penicillin in a Vaccinated Population of Children with Sickle Cell Disorder

Louise Smith, RCN MSc, Elizabeth Ryan, MB ChB, Russell D Keenan, MBChB, PhD FRCP, FRCPath, Rekha Thangavelu, MB ChB FRCP FRCPath

Blood (2018) 132 (Supplement 1): 4927.

https://doi.org/10.1182/blood-2018-99-119768

Published: 2018

Journal Articles

The SMART-IgG Anti-hC5 Antibody (SKY59/RO7112689) Has Favorable PK, PD, Subcutaneous Bioavailability, and Safety Profile in Phase I HV Study

Alexander Roeth, MD, Nagy Zsolt, MD PhD, Miklos Egyed, MD, Erica Winter, Joy Hsu, Andreas Dieckmann, Judith Anzures-Cabrera, Marie Mannino, Elana Fernandez, PhD, Gregor Jordan, Barbara Klughammer, PhD, Kenji Shinomiya, Naoki Kotani, Ido Paz-Priel, MD, Angelika Jahreis., MD, PhD

Blood (2017) 130 (Supplement 1): 4750.

https://doi.org/10.1182/blood.V130.Suppl_1.4750.4750

Published: 2017

Journal Articles

Open Splenectomy in Chronic Immune Thrombocytopenia and Its Early Complications: Still a Safe Option in Resource Limited Setting

Rajiv Kumar, MBBS, MD DM, Divya Bansal, MD DM, Manoranjan Mahapatra, MD, Rajan Kapoor, MD DM, Pravas Mishra, MD DM, Sunil Chumber, MS

Blood (2017) 130 (Supplement 1): 4855.

https://doi.org/10.1182/blood.V130.Suppl_1.4855.4855

Published: 2017

Journal Articles

Eculizumab treatment and impaired opsonophagocytic killing of meningococci by whole blood from immunized adults

Monica Konar, Dan M. Granoff

Blood (2017) 130 (7): 891–899.

https://doi.org/10.1182/blood-2017-05-781450

Published: 2017

Includes: Supplemental data

Journal Articles

Effect of Complement Inhibition By Anti-C5 (Eculizumab) or a Small Molecule Inhibitor of Factor D (ACH-4471) on Survival of Meningococci in Blood from Vaccinated Adults

Monica Konar, PhD, Eduardo Lujan, Dan Granoff, MD

Blood (2016) 128 (22): 2429.

https://doi.org/10.1182/blood.V128.22.2429.2429

Published: 2016

Journal Articles

Evaluation of Bacteria-Mediated Potential "Bystander" Hemolysis of PNH RED CELLS I n Vitro : NO Evidence of Significant Complement Classical or Lectin Pathway-Mediated Hemolysis Induced by Microorganisms

Xuan Yuan, MD MSc, Guangwei Yang, PhD, Jane A Thanassi, Manuel D Galvan, PhD, Steven D Podos, PhD, Mingjun Huang, PhD, Robert A. Brodsky, MD

Blood (2016) 128 (22): 2431.

https://doi.org/10.1182/blood.V128.22.2431.2431

Published: 2016

Journal Articles

Pregnancy-Associated Atypical Hemolytic Uremic Syndrome (aHUS), Treated with Eculizumab

Eudokia M. Mandala, Associate Professor, Spyridon Gkiouzepas, MD, Efstratios Kasimatis, MD, Christos Lafaras, MD PhD, Parthenis Chalevas, MD, Konstantina Tsioni, MD PhD, Krystallia Kyrka, MD, Dominiki Oikonomidou, MD PhD, Konstantinos Dinas, Assistant Professor, Aristotelis Loufopoulos, Professor, George Efstratiadis, Professor, Garipidou Vasilia, Professor, Anastasios-Alexandros Garyfallos, Professor

Blood (2014) 124 (21): 5019.

https://doi.org/10.1182/blood.V124.21.5019.5019

Published: 2014

Journal Articles

Serologic Response to Meningococcal Vaccination in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) for the Chronic Treatment with the Terminal Complement Inhibitor Eculizumab

Alexander Roeth, MD, Ferras Alashkar, MD, Doerte Herich-Terhuerne, Johannes Elias, MD, Ulrich Vogel, MD, Ulrich Duehrsen

Blood (2014) 124 (21): 4380.

https://doi.org/10.1182/blood.V124.21.4380.4380

Published: 2014

Journal Articles

Treatment Of Infection-Associated Purpura Fulminans With Protein C Zymogen Is Associated With a High Survival Rate

Paul Knoebl, MD, Peter Schellongowski, MD, Thomas Staudinger, MD, Wolfgang R. Sperr, MD, Christian Scheibenpflug, MD

Blood (2013) 122 (21): 3606.

https://doi.org/10.1182/blood.V122.21.3606.3606

Published: 2013

Journal Articles

Long-Term Safety of Sustained Eculizumab Treatment in Patients with Paroxysmal Nocturnal Hemoglobinuria

Jeffrey Szer, MBBS, Petra Muus, MD, PhD, Alexander Roeth, MD, M.O Elebute, MD, FRCP, FRCPath, Antonio M. Risitano, MD, PhD, Hubert Schrezenmeier, MD, Jaroslaw P. Maciejewski, MD, PhD, Alvaro Urbano-Ispizua, MD, Carlos Manuel de Castro, III, MD, Gérard Socié, MD PhD, Robert A. Brodsky, MD

Blood (2012) 120 (21): 1260.

https://doi.org/10.1182/blood.V120.21.1260.1260

Published: 2012

Journal Articles

Vaccine Response In Recipients of HLA Mismatched Unrelated Double Unit Cord Blood Transplantation (CBT).

Trudy N Small, M.D, Christine Scura Iovino, APRN-BC, FNP-C, Michelle Abboud, RN, BSN, OCN, Marissa Lubin, BA, Esperanza Papadopoulos, MD, Andromachi Scaradavou, MD, Juliet N Barker, MBBS, (Hons), FRACP

Blood (2010) 116 (21): 1247.

https://doi.org/10.1182/blood.V116.21.1247.1247

Published: 2010

Journal Articles

Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion

Audrey Varin, Subhankar Mukhopadhyay, Georges Herbein, Siamon Gordon

Blood (2010) 115 (2): 353–362.

https://doi.org/10.1182/blood-2009-08-236711

Published: 2010

Includes: Supplemental data

Journal Articles

Impaired maintenance of naturally acquired T-cell memory to the meningococcus in patients with B-cell immunodeficiency

Begonia Morales-Aza, Sarah J. Glennie, Tomaz Pereira Garcez, Victoria Davenport, Sarah L. Johnston, Neil A. Williams, Robert S. Heyderman

Blood (2009) 113 (18): 4206–4212.

https://doi.org/10.1182/blood-2008-08-171587

Published: 2009

Journal Articles

Immunogenicity of the Tetravalent Protein-Conjugated Meningococcal Vaccine in Recipients of Related and Unrelated Allogeneic Hematopoietic Cell Transplants (HCT)

Michelle Mahler, M.D., Nancy A Kernan, MD, Farid Boulad, MD, Susan Prockop, MD, Andromachi Scaradavou, M.D., Esperanza B Papadopoulos, MD, Heidi Abendroth, PNP, Anne Casson, PNP, Catherine Copeland, PNP, Maura Murphy, PNP, Joanne Torok-Castanza, FNP, Richard J. O’Reilly, MD, Trudy N. Small, MD

Blood (2008) 112 (11): 1163.

https://doi.org/10.1182/blood.V112.11.1163.1163

Published: 2008

Journal Articles

Sustained Improvements in Transfusion Requirements, Fatigue and Thrombosis with Eculizumab Treatment in Paroxysmal Nocturnal Hemoglobinuria.

Gerard Socié, MD, PhD, Peter Hillmen, MB ChB, Petra Muus, MD, PhD, Jörg Schubert, MD, Ulrich Dührsen, DM, Antonio M. Risitano, MD PhD, Russell P. Rother, PhD, Robert A. Brodsky, MD, Jeffrey Szer, MB BS

Blood (2007) 110 (11): 3672.

https://doi.org/10.1182/blood.V110.11.3672.3672

Published: 2007

Journal Articles

Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections

Tom Sprong, Dirk Roos, Corry Weemaes, Chris Neeleman, Christel L. M. Geesing, Tom Eirik Mollnes, Marcel van Deuren

Blood (2006) 107 (12): 4865–4870.

https://doi.org/10.1182/blood-2005-07-2820

Published: 2006

Journal Articles

Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis

Tom Sprong, Petter Brandtzaeg, Michael Fung, Anne M. Pharo, E. Arne Høiby, Terje E. Michaelsen, Audun Aase, Jos W. M. van der Meer, Marcel van Deuren, Tom E. Mollnes

Blood (2003) 102 (10): 3702–3710.

https://doi.org/10.1182/blood-2003-03-0703

Published: 2003

NARROW

Comparative Evaluation of Complement Factor D, C3, and C5 Inhibitors on Serum Bactericidal Activity Against Neisseria Meningitidis Isolates

No Demonstrable Benefit of Penicillin in a Vaccinated Population of Children with Sickle Cell Disorder

The SMART-IgG Anti-hC5 Antibody (SKY59/RO7112689) Has Favorable PK, PD, Subcutaneous Bioavailability, and Safety Profile in Phase I HV Study

Open Splenectomy in Chronic Immune Thrombocytopenia and Its Early Complications: Still a Safe Option in Resource Limited Setting

Eculizumab treatment and impaired opsonophagocytic killing of meningococci by whole blood from immunized adults

Effect of Complement Inhibition By Anti-C5 (Eculizumab) or a Small Molecule Inhibitor of Factor D (ACH-4471) on Survival of Meningococci in Blood from Vaccinated Adults

Evaluation of Bacteria-Mediated Potential "Bystander" Hemolysis of PNH RED CELLS I n Vitro : NO Evidence of Significant Complement Classical or Lectin Pathway-Mediated Hemolysis Induced by Microorganisms

Pregnancy-Associated Atypical Hemolytic Uremic Syndrome (aHUS), Treated with Eculizumab

Serologic Response to Meningococcal Vaccination in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) for the Chronic Treatment with the Terminal Complement Inhibitor Eculizumab

Treatment Of Infection-Associated Purpura Fulminans With Protein C Zymogen Is Associated With a High Survival Rate

Long-Term Safety of Sustained Eculizumab Treatment in Patients with Paroxysmal Nocturnal Hemoglobinuria

Vaccine Response In Recipients of HLA Mismatched Unrelated Double Unit Cord Blood Transplantation (CBT).

Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion

Impaired maintenance of naturally acquired T-cell memory to the meningococcus in patients with B-cell immunodeficiency

Immunogenicity of the Tetravalent Protein-Conjugated Meningococcal Vaccine in Recipients of Related and Unrelated Allogeneic Hematopoietic Cell Transplants (HCT)

Sustained Improvements in Transfusion Requirements, Fatigue and Thrombosis with Eculizumab Treatment in Paroxysmal Nocturnal Hemoglobinuria.

Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections

Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis

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American Society of Hematology

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American Society of Hematology

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