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Journal Articles

Platelet Desialylation As a Predictive Marker in Childhood Immune Thrombocytopenia (ITP)

Leona Raskova Kafkova, MSc, PhD, Diana Brokesova, MSc, Zbynek Novak, MD, Milan Raska, Prof. MD MSc, PhD, Dagmar Pospisilova, Prof MD PhD, Jana Volejnikova, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 221.
https://doi.org/10.1182/blood-2019-122095
Published: 2019
Journal Articles

Autoantibody Mediated Desialylation Impairs Human Thrombopoiesis and Platelet Life Span

Irene Marini, Jan Zlamal, Lisann Pelzel, Wolfgang Bethge, Christoph Faul, MD, Ursula Holzer, PD Dr. MD, Karina Althaus, Tamam Bakchoul, Prof. Dr.
Journal: Blood
Blood (2019) 134 (Supplement_1): 2346.
https://doi.org/10.1182/blood-2019-131725
Published: 2019
Journal Articles

Acute Influenza A Virus Infection Affects Cell Cycle and Lineage Output of Hematopoietic Stem Cells

Marcel E G Rommel, Lisa Walz, Dr., Saskia Kohlscheen, Dr., Franziska Schenk, Yvonne Krebs, Kevin Wittwer, M.Sc., Veronika von Messling, Prof. Dr., Ute Modlich, Prof. Dr. Dr.
Journal: Blood
Blood (2019) 134 (Supplement_1): 2467.
https://doi.org/10.1182/blood-2019-126482
Published: 2019
Journal Articles

High-Dose Dexamethasone (HD-DXM) Plus Oseltamivir Versus High-Dose Dexamethasone for Treatment of Adult Primary Immune Thrombocytopenia: Interim Analysis of a Prospective, Multicenter, Randomized, Controlled Trial

Lu Sun, PhD, Xinguang Liu, Hai Zhou, Hongguo Zhao, Chenglu Yuan, Daqi Li, Zhencheng Wang, Yu Hou, Jun Peng, Ming Hou
Journal: Blood
Blood (2019) 134 (Supplement_1): 900.
https://doi.org/10.1182/blood-2019-121825
Published: 2019
Journal Articles

In Non-Selected Patients Treated for Influenza, Oseltamivir, a Glycosialidase Inhibitor, Demonstrates Improvement in Platelet Counts Compared to Time of Dosing, but Not over Baseline Levels

Sabina I. Cashin, BS, Melissa M. Lee-Sundlov, PhD, Karin M. Hoffmeister, MD, Laura C. Michaelis, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3626.
https://doi.org/10.1182/blood.V130.Suppl_1.3626.3626
Published: 2017
Journal Articles

Desialylation of Megakaryocytes Diminishes Platelet Production By Disrupting Megakaryocyte Adhesion, Migration and Proplatelet Formation in Chronic Immune Thrombocytopenia

Qian-Ming Wang, Jia-Min Zhang, Xiao-Lu Zhu, Hai-Xia Fu, Meng Lv, Yuan Kong, Ying-Jun Chang, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang, Xiao-Hui Zhang
Journal: Blood
Blood (2016) 128 (22): 165.
https://doi.org/10.1182/blood.V128.22.165.165
Published: 2016
Journal Articles

Platelet Desialylation: A Novel Mechanism of Fc-Independent Platelet Clearance and a Potential Diagnostic Biomarker and Therapeutic Target in immune Thrombocytopenia

June Li, MSc, Dianne Evertdina van der Wal, PhD, Guangheng Zhu, MD, Miao Xu, MSc, MD, Issaka Yougbare, PhD, Li Ma, PhD, Brian Vadasz, BSc, Renata Grozovsky, PhD, Min Ruan, MD, Lingyan Zhu, MD, Qingshu Zeng, MD, Lili Tao, MD, Zhi-min Zhai, MD, Jun Peng, MD, Ming Hou, MD, Valery Leytin, PhD, John J. Freedman, MD, Karin M Hoffmeister, MD, Heyu Ni, MD PhD
Journal: Blood
Blood (2014) 124 (21): 467.
https://doi.org/10.1182/blood.V124.21.467.467
Published: 2014
Journal Articles

Desialylation Induces Apoptosis and Phagocytosis of Platelets in Patients with Prolonged Isolated Thrombocytopenia after Allogeneic Hematopoietic Stem Cell Transplantation

Qian-ming Wang, Xiao-Hui Zhang, MD, PhD, Fei-er Feng, Chen-cong Wang, Wei Han, Huan Chen, Lan-ping Xu, Xiao Jun Huang
Journal: Blood
Blood (2014) 124 (21): 432.
https://doi.org/10.1182/blood.V124.21.432.432
Published: 2014
Journal Articles

Sialic Acid Loss Regulates Platelet Survival and Integrity

Renata Grozovsky, PhD, Gerard Jansen, MD, PhD, MSC, Karin M. Hoffmeister, MD
Journal: Blood
Blood (2013) 122 (21): 3504.
https://doi.org/10.1182/blood.V122.21.3504.3504
Published: 2013
Journal Articles

Desialylation: A Novel Platelet Clearance Mechanism and a Potential New Therapeutic Target in Anti-GPIb Antibody Mediated Thrombocytopenia

Dianne E. van Der Wal, PhD, Guangheng Zhu, MD, June Li, BSc, Brian Vadasz, BSc, Yougbare Issaka, PhD, Sean Lang, MSc, John Freedman, MD, Heyu Ni, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 265.
https://doi.org/10.1182/blood.V120.21.265.265
Published: 2012
Journal Articles

Inhibition of Sialic Acid Loss Greatly Improves Survival of Refrigerated Platelets

Gerard Jansen, MD, PhD, MSC, Emma C Josefsson, PhD, Qiyong Peter Liu, PhD, Viktoria Rumjantseva, PhD, Herve Falet, PhD, Renata Grozovsky, PhD, Wolfgang Bergmeier, PhD, Denisa D. Wagner, PhD, John H. Hartwig, PhD, Karin M. Hoffmeister, MD
Journal: Blood
Blood (2011) 118 (21): 1133.
https://doi.org/10.1182/blood.V118.21.1133.1133
Published: 2011
Journal Articles

The Hepatic Asialoglycoprotein Receptor Regulates Platelet Homeostasis

Renata Grozovsky, Gerard Jansen, MD, PhD, MSC, Karin M. Hoffmeister, MD
Journal: Blood
Blood (2010) 116 (21): 2025.
https://doi.org/10.1182/blood.V116.21.2025.2025
Published: 2010
Journal Articles

CD15 (Lewis x) Expression in Human Myeloid Cell Differentiation Is Regulated by Sialidase Activity.

Samah Z. Gadhoum, PhD, Robert Sackstein, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 1931.
https://doi.org/10.1182/blood.V108.11.1931.1931
Published: 2006
Journal Articles

Clinical Impact of Respiratory Viruses in Haematopoietic Stemcell Transplantation; a Firm Association with Bronchiolitis Obliterans.

Birgitta Versluys, MD, M. Bierings, MD, PhD, R. Schuurman, MD, PhD, B. Ewijk, MD, J.J. Boelens, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 3230.
https://doi.org/10.1182/blood.V106.11.3230.3230
Published: 2005