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Journal Articles

Gene Editing ELANE in Human Hematopoietic Stem and Progenitor Cells Reveals Disease Mechanisms and Therapeutic Strategies for Severe Congenital Neutropenia

Shuquan Rao, PhD, Josias Brito-Frazao, Anna V. Serbin, Qiuming Yao, PhD, Kevin Luk, Yuxuan Wu, PhD, Jing Zeng, MD, Chunyan Ren, PhD, Ruth Watkinson, Myriam Armant, PhD, Luca Pinello, PhD, Akiko Shimamura, MD PhD, Benhur Lee, Scot A. Wolfe, PhD, Peter E. Newburger, MD, Daniel E. Bauer, MD PhD

Blood (2019) 134 (Supplement_1): 3.

https://doi.org/10.1182/blood-2019-131073

Published: 2019

Journal Articles

Inducible Expression of Mutant ELANE Correlates with Disruption of Differentiation Program, but Not the Unfolded Protein Response

Bhavuk Garg, PhD, Hrishikesh M Mehta, PhD, Ralph Kamel, Marshall S. Horwitz, MD PhD, Seth J. Corey, MD

Blood (2019) 134 (Supplement_1): 103.

https://doi.org/10.1182/blood-2019-127409

Published: 2019

Journal Articles

Clinical Evidence of Granulocyte-Monocyte Progenitor (GMP) Stem Cell Involvement in Plinabulin's Mechanism of Action (MoA) for the Prevention of Docetaxel (Doc) Chemotherapy (Chemo)-Induced Neutropenia (CIN)

Douglas W. Blayney, MD, Lan Huang, PhD, Ramon Mohanlal, PhD MD

Blood (2019) 134 (Supplement_1): 4861.

https://doi.org/10.1182/blood-2019-127227

Published: 2019

Journal Articles

Impact of Hypothermia on Differentiation and Maturation of Neutrophils

Yusuke Torikoshi, Asumi Yokota, PhD, Naoka Kamio, MD, Atsushi Sato, MD, Tsukimi Shouji, Takahiro Kashiwagi, Yasuo Miura, MD PhD, Taira Maekawa, MD PhD, Hideyo Hirai, MD

Blood (2018) 132 (Supplement 1): 2393.

https://doi.org/10.1182/blood-2018-99-114651

Published: 2018

Journal Articles

Incidence of Neutropenic Fever at a Safety Net Hospital in Cancer Chemotherapy Patients Receiving Prophylactic Pegfilgrastim Manual Injection Compared to the on-Body Auto-Injector

Atin Jindal, MD, Jan Kover, BPharm, Vanja Raduka, PharmD, R.Ph, Timothy E. O'Brien, MD

Blood (2018) 132 (Supplement 1): 4709.

https://doi.org/10.1182/blood-2018-99-114282

Published: 2018

Journal Articles

Single-Cell Methylome and Transcriptome High-Resolution Maps Define the Effects of Epigenetic Modifiers on the Landscape of Hematopoietic Differentiation

Franco Izzo, PhD, Asaf Poran, Stanley Chun-Wei Lee, PhD, Ronan Chaligne, PhD, Federico Gaiti, PhD, Steven Kothen-Hill, MS, Rafael Schulman, BS, Michelle Ki, Kenigsberg Ephraim, PhD, Omar Abdel-Wahab, MD, Dan A. Landau, MD PhD

Blood (2017) 130 (Supplement 1): 559.

https://doi.org/10.1182/blood.V130.Suppl_1.559.559

Published: 2017

Journal Articles

Changes in Gene Expression during G-CSF-Induced Emergency Granulopoiesis in Humans

Corinna Cavan Pedersen, M.Sc. Eng., Rehannah Borup, M.Sc., Anne Fischer-Nielsen, MD PhD, Helena Mora-Jensen, PhD, Anna Fossum, M.Sc., Jack B. Cowland, Niels Borregaard

Blood (2015) 126 (23): 2202.

https://doi.org/10.1182/blood.V126.23.2202.2202

Published: 2015

Journal Articles

Identification of the Origin of Eosinophils

Andre Olsson, PhD, Nathan Salomonis, PhD, Harinder Singh, H. Leighton Grimes, PhD

Blood (2015) 126 (23): 886.

https://doi.org/10.1182/blood.V126.23.886.886

Published: 2015

Journal Articles

Neutrophils Modulate Osteoblastic Niche for Hematopoietic Progenitors Via Prostaglandin E2 Production Triggered By Sympathetic Nervous System

Yuko Kawano, MD, Chie Fukui, Kanako Wakahashi, MD, Shinichi Ishii, MD, Tomohide Suzuki, MD, Mari Sato, DDS,PhD, Noboru Asada, MDPhD, Hiroki Kawano, MD PhD, Kentaro Minagawa, MD PhD, Akiko Sada, MD PhD, Satoshi Uematsu, MDPhD, Shizuo Akira, MD PhD, Toshimitsu Uede, MD PhD, Shuh Narumiya, MDPhD, Toshimitsu Matsui, MD PhD, Yoshio Katayama, MD PhD

Blood (2014) 124 (21): 769.

https://doi.org/10.1182/blood.V124.21.769.769

Published: 2014

Journal Articles

Pre-Clinical Studies of a Novel Recombinant Human Granulocyte Colony-Stimulating Factor

Zhihua Ren, PhD, Wenhong Jiang, B.S., Zhenwang Jie, M.S., Xiaoxiao Liu, M.S., Fei Xia, M.S., Jie Fan, M.S., Keyong Shi, PhD, Xinxin Ding, PhD, Wei Dai, PhD, Yongping Jiang, PhD

Blood (2014) 124 (21): 2920.

https://doi.org/10.1182/blood.V124.21.2920.2920

Published: 2014

Journal Articles

Processing of Neutrophil α-Defensins Does Not Rely on Serine Proteases in Vivo

Andreas Glenthoj, MDPhD, Katrin Nickles, DMD, Jack B Cowland, PhD, Niels Borregaard, MDPhD

Blood (2014) 124 (21): 1400.

https://doi.org/10.1182/blood.V124.21.1400.1400

Published: 2014

Journal Articles

Timing of Primary Prophylaxis G-CSF Use during Chemotherapy in Elderly Patients with NHL

Shuling Li, PhD, Iberia Romina Sosa, MD PhD, Julia T Molony, MS, John H Page, MD ScD, Richard L Barron, MS, Jiannong Liu, PhD, Phuong Khanh Morrow, MD, Scott Stryker, MD DrPH, John F Acquavella, PhD, Allan J Collins, MD FACP

Blood (2014) 124 (21): 6013.

https://doi.org/10.1182/blood.V124.21.6013.6013

Published: 2014

Journal Articles

Expression of Core-Binding Factor-β Is Regulated By Mir-143 and Mir-223 during Granulopoiesis

Maria Torp Larsen, MD PhD, Anette Borgkilde, MSc, Stine Novrup Clemmensen, MD, Niels Borregaard, Professor of Hematology, Jack B. Cowland, MSc, PhD

Blood (2014) 124 (21): 2721.

https://doi.org/10.1182/blood.V124.21.2721.2721

Published: 2014

Journal Articles

A Novel Role For Histone Deacetylase 11 (HDAC11) As a Regulator Of Neutrophil Function and Differentiation In Normal and Malignant Hematopoesis

Eva Sahakian, Ph.D, John Powers, B.S., Jie Chen, M.A., Allison Distler, B.S., Jennifer Rock-Klotz, B.S., Susan Deng, B.S., Sheng Wei, MD, Eduardo M. Sotomayor, MD, Javier Pinilla-Ibarz, M.D. Ph.D., Pedro Horna, M.D.

Blood (2013) 122 (21): 2267.

https://doi.org/10.1182/blood.V122.21.2267.2267

Published: 2013

Journal Articles

miRNA Profiling in Human Granulopoiesis and in Activated Neutrophils From Skin Window.

Maria Torp Larsen, MD, Christoffer Hother, MD, Mattias Hager, MSc, Corinna Cavan Pedersen, MSc, Lars Jacobsen, MSc, Niels Borregaard, Jack B Cowland

Blood (2012) 120 (21): 2136.

https://doi.org/10.1182/blood.V120.21.2136.2136

Published: 2012

Journal Articles

Olfactomedin 4, An Indicator of the Existence of Neutrophil Subsets.

Stine Novrup Clemmensen, Sara Roervig, Jonathan Wren, PhD, Martin Illemann, PhD, Andreas Glenthoj, Helena Mora-Jensen, Elisabeth Cramer, Maria Torp Larsen, Lars C. Jacobsen, Jack B Cowland, MS, PhD, Niels Borregaard, MD, PhD

Blood (2010) 116 (21): 3775.

https://doi.org/10.1182/blood.V116.21.3775.3775

Published: 2010

Journal Articles

A1AT In Human Neutrophil Granulocytes.

Stine Novrup Clemmensen, Lars C. Jacobsen, Sara Roervig, Bent Adel Hansen, Martin Iversen, Jack B Cowland, MS, PhD, Bo van Deurs, Bjarke Askaa, Niels Borregaard, MD, PhD

Blood (2010) 116 (21): 3784.

https://doi.org/10.1182/blood.V116.21.3784.3784

Published: 2010

Journal Articles

Loss of Tafazzin (TAZ) Function and Accelerated Apoptosis of Human Bone Marrow Stem and Myeloid Progenitors in Barth Syndrome.

Vahagn Makaryan, MD, Yigal Dror, MD, Andrew A Aprikyan, PhD

Blood (2009) 114 (22): 549.

https://doi.org/10.1182/blood.V114.22.549.549

Published: 2009

Journal Articles

Knock-Down of TAZ Gene Expression: A Model of Barth Syndrome with Accelerated Apoptosis of Myeloid Progenitor Cells Improved upon Treatment with Caspase-Specific Inhibitor

Vahagn Makaryan, MD, David C. Dale, MD, Andrew A Aprikyan, PhD

Blood (2008) 112 (11): 3558.

https://doi.org/10.1182/blood.V112.11.3558.3558

Published: 2008

Journal Articles

The in Vivo Response of Patients Suffering from Severe Congenital Neutropenia (CN) to G-CSF Is Due to “Emergency” Granulopoiesis Induced by C/EBPβ

Lan Dan, Basant Kumar Thakur, Julia Skokowa, Karl Welte

Blood (2008) 112 (11): 315.

https://doi.org/10.1182/blood.V112.11.315.315

Published: 2008

NARROW

Gene Editing ELANE in Human Hematopoietic Stem and Progenitor Cells Reveals Disease Mechanisms and Therapeutic Strategies for Severe Congenital Neutropenia

Inducible Expression of Mutant ELANE Correlates with Disruption of Differentiation Program, but Not the Unfolded Protein Response

Clinical Evidence of Granulocyte-Monocyte Progenitor (GMP) Stem Cell Involvement in Plinabulin's Mechanism of Action (MoA) for the Prevention of Docetaxel (Doc) Chemotherapy (Chemo)-Induced Neutropenia (CIN)

Impact of Hypothermia on Differentiation and Maturation of Neutrophils

Incidence of Neutropenic Fever at a Safety Net Hospital in Cancer Chemotherapy Patients Receiving Prophylactic Pegfilgrastim Manual Injection Compared to the on-Body Auto-Injector

Single-Cell Methylome and Transcriptome High-Resolution Maps Define the Effects of Epigenetic Modifiers on the Landscape of Hematopoietic Differentiation

Changes in Gene Expression during G-CSF-Induced Emergency Granulopoiesis in Humans

Identification of the Origin of Eosinophils

Neutrophils Modulate Osteoblastic Niche for Hematopoietic Progenitors Via Prostaglandin E2 Production Triggered By Sympathetic Nervous System

Pre-Clinical Studies of a Novel Recombinant Human Granulocyte Colony-Stimulating Factor

Processing of Neutrophil α-Defensins Does Not Rely on Serine Proteases in Vivo

Timing of Primary Prophylaxis G-CSF Use during Chemotherapy in Elderly Patients with NHL

Expression of Core-Binding Factor-β Is Regulated By Mir-143 and Mir-223 during Granulopoiesis

A Novel Role For Histone Deacetylase 11 (HDAC11) As a Regulator Of Neutrophil Function and Differentiation In Normal and Malignant Hematopoesis

miRNA Profiling in Human Granulopoiesis and in Activated Neutrophils From Skin Window.

Olfactomedin 4, An Indicator of the Existence of Neutrophil Subsets.

A1AT In Human Neutrophil Granulocytes.

Loss of Tafazzin (TAZ) Function and Accelerated Apoptosis of Human Bone Marrow Stem and Myeloid Progenitors in Barth Syndrome.

Knock-Down of TAZ Gene Expression: A Model of Barth Syndrome with Accelerated Apoptosis of Myeloid Progenitor Cells Improved upon Treatment with Caspase-Specific Inhibitor

The in Vivo Response of Patients Suffering from Severe Congenital Neutropenia (CN) to G-CSF Is Due to “Emergency” Granulopoiesis Induced by C/EBPβ

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American Society of Hematology

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American Society of Hematology

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