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Journal Articles

Post-Translational Mechanisms of NT5C2 Activation As Non-Genetic Drivers of Chemotherapy Resistance in Relapsed Acute Lymphoblastic Leukemia

Clara Reglero, PhD, Dieck L. Chelsea, PhD, Jui Wan Loh, Hossein Khiabanian, PhD, Adolfo Ferrando, MD, PhD

Blood (2019) 134 (Supplement_1): 728.

https://doi.org/10.1182/blood-2019-128615

Published: 2019

Journal Articles

Genetics and mechanisms of NT5C2-driven chemotherapy resistance in relapsed ALL

Chelsea L. Dieck, Adolfo Ferrando

Blood (2019) 133 (21): 2263–2268.

https://doi.org/10.1182/blood-2019-01-852392

Published: 2019

Journal Articles

Mechanisms of NT5C2 mutations Driving Thiopurine Resistance in Acute Lymphoblastic Leukemia

Chelsea Dieck, Gannie Tzoneva, PhD, Farhad Forouhar, Zachary Carpenter, PhD, Alberto Ambesi-Impiombato, Marta Sanchez-Martin, PhD, Liang Tong, Adolfo A. Ferrando, MD PhD

Blood (2017) 130 (Supplement 1): 715.

https://doi.org/10.1182/blood.V130.Suppl_1.715.715

Published: 2017

Journal Articles

Clonal Evolution Mechanisms and Collateral Sensitivity to Impdh Inhibitor Therapy in Relapsed Lymphoblastic Leukemia

Chelsea Dieck, Gannie Tzoneva, PhD, Koichi Oshima, MD PhD, Alberto Ambesi-Impiombato, Marta Sanchez-Martin, PhD, Maria Luisa Sulis, MD, Motohiro Kato, MD PhD, Katsuyoshi Koh, MD, Maddalena Paganin, PhD, Giuseppe Basso, MD, Julie M. Gastier-Foster, PhD, Mignon L. Loh, MD, Renate Kirschner-Schwabe, PhD, Chioma Madubata, Raul Rabadan, Adolfo A. Ferrando, MD PhD

Blood (2017) 130 (Supplement 1): 2602.

https://doi.org/10.1182/blood.V130.Suppl_1.2602.2602

Published: 2017

Journal Articles

Mutational Profiling of Acute Lymphoblastic Leukemia with Testicular Relapse

Ling-wen Ding, PhD, Qiao-Yang Sun, PhD, Anand Mayakonda, Kar-Tong Tan, Wenwen Chien, De-Chen Lin, Yan-Yi Jiang, Liang Xu, Manoj Garg, PhD, Michael Lill, MD, Henry Yang, PhD, Allen Yeoh, MD, H. Phillip Koeffler, MD

Blood (2016) 128 (22): 2809.

https://doi.org/10.1182/blood.V128.22.2809.2809

Published: 2016

Journal Articles

NT5C2 As a Major Contributor to Thiopurine Resistance at ALL Relapse Via Multiple Mechanisms

Takaya Moriyama, MD, Julia Meyer, PhD, Shuguang Liu, PhD, Xujie Zhao, Zhaohong Ying, MD, William L. Carroll, MD, Jun J Yang, PhD

Blood (2015) 126 (23): 446.

https://doi.org/10.1182/blood.V126.23.446.446

Published: 2015

Journal Articles

Diagnostic Power of Laser Assisted Optical Rotational Cell Analyzer (LoRRca MaxSis) Evaluated in 118 Patients Affected By Hereditary Hemolytic Anemias

Paola Bianchi, PhD, Anna Zaninoni, BSc, PhD, Elisa Fermo, PhD, Cristina Vercellati, BSc, Marcello Anna Paola, BSc, Alberto Zanella, MD, Agostino Cortelezzi, MD, Wilma Barcellini, MD

Blood (2015) 126 (23): 942.

https://doi.org/10.1182/blood.V126.23.942.942

Published: 2015

Journal Articles

Targeted Deep Sequencing of Genetic Alterations Identified By Whole Exome Sequencing Reveals Clonal Evolution in Pediatric T-Lymphoblastic Leukemia

Blood (2014) 124 (21): 491.

https://doi.org/10.1182/blood.V124.21.491.491

Published: 2014

Journal Articles

Clinical Significance of NT5C2 Mutations in Children with First Relapse of B-Cell Precursor Acute Lymphoblastic Leukemia

Jana Hof, MSc, Annabell Szymansky, MSc, Arend von Stackelberg, MD, Cornelia Eckert, PhD, Renate Kirschner-Schwabe, PhD

Blood (2014) 124 (21): 3789.

https://doi.org/10.1182/blood.V124.21.3789.3789

Published: 2014

Journal Articles

Genetic Landscapes Of Childhood T-Cell Acute Lymphoblastic Leukemia

Masafumi Seki, MD, Kenichi Yoshida, MD, Yusuke Sato, MD, Yuichi Shiraishi, PhD, Kenichi Chiba, PhD, Hiroko Tanaka, BA, Motohiro Kato, MD, PhD, Mitsuteru Hiwatari, MD, PhD, Katsuyoshi Koh, MD, Ryoji Hanada, MD, Masashi Sanada, MD, Satoru Miyano, PhD, Akira Oka, MD, PhD, Yasuhide Hayashi, MD, PhD, Seishi Ogawa, MD, PhD, Junko Takita, MD, PhD

Blood (2013) 122 (21): 3786.

https://doi.org/10.1182/blood.V122.21.3786.3786

Published: 2013

Journal Articles

Comparison Of Mutational Profiles Of Diagnosis and Relapsed Pediatric B-Acute Lymphoblastic Leukemia: A Report From The COG ALL Target Project

Blood (2013) 122 (21): 824.

https://doi.org/10.1182/blood.V122.21.824.824

Published: 2013

Journal Articles

Platelet Reactivity and CD39 Ectonucleotidase Activities in Cryptogenic Stroke

Aaron J Marcus, MD, Joan HF Drosopoulos, PhD, Kim E Olson, MD, Ranjini Anand, MS, Dana Leifer, MD, Jorge R Kizer, MD

Blood (2012) 120 (21): 3397.

https://doi.org/10.1182/blood.V120.21.3397.3397

Published: 2012

Journal Articles

Deficiency of CD73/ecto-5′-nucleotidase in mice enhances acute graft-versus-host disease

Hiroki Tsukamoto, Petya Chernogorova, Korcan Ayata, Ulrike V. Gerlach, Ankur Rughani, Jerry W. Ritchey, Jayanthi Ganesan, Marie Follo, Robert Zeiser, Linda F. Thompson, Marco Idzko

Blood (2012) 119 (19): 4554–4564.

https://doi.org/10.1182/blood-2011-09-375899

Published: 2012

Journal Articles

Deficiency of CD73/Ecto-5'-Nucleotidase Enhances Acute Graft-Versus-Host Disease

Petya Chernogorova, Hiroki Tsukamoto, Ph.D., Korcan Ayata, Ph.D., Ulrike V. Gerlach, M.D., Ankur Rughani, Jayanthi Ganesan, Marie Follo, PhD, Linda F. Thompson, Ph.D., Marco Idzko, M.D., Robert Zeiser, M.D.

Blood (2011) 118 (21): 312.

https://doi.org/10.1182/blood.V118.21.312.312

Published: 2011

Journal Articles

The Quest for Hb Questembert: A Challenging Case of An Unstable Hb Variant

Kavita Natarajan, Niren Patel, MBBS, Lina Zhuang, MD, Harris Carmichael, Elizabeth Manaloor, MD, Abdullah Kutlar, MD, Ferdane Kutlar, MD

Blood (2010) 116 (21): 4814.

https://doi.org/10.1182/blood.V116.21.4814.4814

Published: 2010

Journal Articles

In-Vitro Efficacy of the Deoxyguanoside Analogs Forodesine (BCX-1777) and ARA-G in Pediatric Acute Lymphoblastic Leukemia.

Irene Homminga, MD, Michel C. Zwaan, MD, PhD, Amel Seghouani, MD, Chantal Y. Manz, PhD, Shanta Bantia, PhD, Wilco Smits, Rob Pieters, MD, PhD, Jules P.P. Meijerink, PhD

Blood (2009) 114 (22): 2038.

https://doi.org/10.1182/blood.V114.22.2038.2038

Published: 2009

Journal Articles

Raft Localization and Nucleotidase Activity of CD39 Depends on Internal Proteolytic Cleavage

Kim E Olson, MD, Joan HF Drosopoulos, PhD, Ashley E Olson, BS, Marinus Johan Broekman, PhD, Aaron J Marcus, MD

Blood (2008) 112 (11): 3925.

https://doi.org/10.1182/blood.V112.11.3925.3925

Published: 2008

Journal Articles

Platelet Reactivity and CD39 Ectonucleotidase Activities in Cryptogenic Stroke

Aaron J. Marcus, MD, Marinus Johan Broekman, PhD, Joan HF Drosopoulos, PhD, Kim E. Olson, MD, Dianne Pulte, MD, Jorge R. Kizer

Blood (2008) 112 (11): 3817.

https://doi.org/10.1182/blood.V112.11.3817.3817

Published: 2008

Journal Articles

Nucleotidase Activity of CD39/NTPDase1 Is Dependent on Internal Proteolytic Cleavage Which Contributes to Lipid Raft Localization.

Kim E. Olson, MD, Marinus Johan Broekman, PhD, Ashley E. Olson, BS, Dianne Pulte, MD, Aaron J. Marcus, MD

Blood (2007) 110 (11): 3634.

https://doi.org/10.1182/blood.V110.11.3634.3634

Published: 2007

Journal Articles

Molecular Characterization of Three New Mutant Enzymes of Pyrimidine 5′-Nucleotidase Causing Hereditary Hemolytic Anemia.

Laurent R. Chiarelli, Simone M. Morera, Paola Rognoni, Paola Bianchi, Elisa Fermo, Alessandro Galizzi, Alberto Zanella, Giovanna Valentini

Blood (2007) 110 (11): 1730.

https://doi.org/10.1182/blood.V110.11.1730.1730

Published: 2007

NARROW

Post-Translational Mechanisms of NT5C2 Activation As Non-Genetic Drivers of Chemotherapy Resistance in Relapsed Acute Lymphoblastic Leukemia

Genetics and mechanisms of NT5C2-driven chemotherapy resistance in relapsed ALL

Mechanisms of NT5C2 mutations Driving Thiopurine Resistance in Acute Lymphoblastic Leukemia

Clonal Evolution Mechanisms and Collateral Sensitivity to Impdh Inhibitor Therapy in Relapsed Lymphoblastic Leukemia

Mutational Profiling of Acute Lymphoblastic Leukemia with Testicular Relapse

NT5C2 As a Major Contributor to Thiopurine Resistance at ALL Relapse Via Multiple Mechanisms

Diagnostic Power of Laser Assisted Optical Rotational Cell Analyzer (LoRRca MaxSis) Evaluated in 118 Patients Affected By Hereditary Hemolytic Anemias

Targeted Deep Sequencing of Genetic Alterations Identified By Whole Exome Sequencing Reveals Clonal Evolution in Pediatric T-Lymphoblastic Leukemia

Clinical Significance of NT5C2 Mutations in Children with First Relapse of B-Cell Precursor Acute Lymphoblastic Leukemia

Genetic Landscapes Of Childhood T-Cell Acute Lymphoblastic Leukemia

Comparison Of Mutational Profiles Of Diagnosis and Relapsed Pediatric B-Acute Lymphoblastic Leukemia: A Report From The COG ALL Target Project

Platelet Reactivity and CD39 Ectonucleotidase Activities in Cryptogenic Stroke

Deficiency of CD73/ecto-5′-nucleotidase in mice enhances acute graft-versus-host disease

Deficiency of CD73/Ecto-5'-Nucleotidase Enhances Acute Graft-Versus-Host Disease

The Quest for Hb Questembert: A Challenging Case of An Unstable Hb Variant

In-Vitro Efficacy of the Deoxyguanoside Analogs Forodesine (BCX-1777) and ARA-G in Pediatric Acute Lymphoblastic Leukemia.

Raft Localization and Nucleotidase Activity of CD39 Depends on Internal Proteolytic Cleavage

Platelet Reactivity and CD39 Ectonucleotidase Activities in Cryptogenic Stroke

Nucleotidase Activity of CD39/NTPDase1 Is Dependent on Internal Proteolytic Cleavage Which Contributes to Lipid Raft Localization.

Molecular Characterization of Three New Mutant Enzymes of Pyrimidine 5′-Nucleotidase Causing Hereditary Hemolytic Anemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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