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Journal Articles

Design and characterization of α1-antitrypsin variants for treatment of contact system–driven thromboinflammation

Steven de Maat, Wariya Sanrattana, Reiner K. Mailer, Naomi M. J. Parr, Martin Hessing, Robert M. Koetsier, Joost C. M. Meijers, Gerard Pasterkamp, Thomas Renné, Coen Maas

Blood (2019) 134 (19): 1658–1669.

https://doi.org/10.1182/blood.2019000481

Published: 2019

Includes: Supplemental data

Journal Articles

Neutrophil Extracellular Traps Are an Intrinsic Feature in Sickle Cell Disease

Emilia Alina Barbu, Venina Marcela Dominical, PhD, Laurel Mendelsohn, BS, James Nichols, RN, Darlene Allen, MT(ASCP), Swee Lay Thein, DSc,FRCP,FRCPath,MBBS,MRCPath,MRCP

Blood (2018) 132 (Supplement 1): 3651.

https://doi.org/10.1182/blood-2018-99-118723

Published: 2018

Journal Articles

Systemic Inflammation Induces Release of Cell-Free DNA from Hematopoietic and Parenchymal Cells in Mice and Human

Anna Kroeze, MD, Anne Jan van der Meer, MD, Arie J Hoogendijk, PhD, Aicha Ait Soussan, C. Ellen van der Schoot, MD PhD, Walter A Wuillemin, MD PhD, Carlijn Voermans, PhD, Tom van der Poll, MD PhD, Sacha S Zeerleder, MD PhD

Blood (2018) 132 (Supplement 1): 1107.

https://doi.org/10.1182/blood-2018-99-114468

Published: 2018

Journal Articles

Targeting Elastase with Alpha1 Anti-Trypsin Reduces Hyperalgesia in Mice with Sickle Cell Disease

Aithanh Nguyen, Sophia Pantano, Waogwende Leonce Song-Naba, BS, Ritu Jha, MSc, Julia Nguyen, BS, Kalpna Gupta, PhD

Blood (2018) 132 (Supplement 1): 724.

https://doi.org/10.1182/blood-2018-99-111872

Published: 2018

Journal Articles

Promyelocytic Extracellular Chromatin Exacerbates Coagulation Disorder in Acute Promyelocytic Leukemia

Muhua Cao, MD, Ruishuang Ma, MD, Xiaoming Wu, MD, Lixiu Wang, MD, Lu Zhao, MD, Yan Zhang, MD, Zhipeng Yao, MD, Tao Li, MD, Junjie Kou, MD PhD, Yayan Bi, MD PhD, Jin Zhou, MD PhD, Jialan Shi, MD PhD

Blood (2016) 128 (22): 3806.

https://doi.org/10.1182/blood.V128.22.3806.3806

Published: 2016

Journal Articles

Canine Neutrophil Extracellular Traps Have Pro-Coagulant and Anti-Fibrinolytic Effects

Unity Jeffery, VetMB PhD DACVP (clinical pathology), Dana N. LeVine, DVM, PhD DACVIM

Blood (2016) 128 (22): 3813.

https://doi.org/10.1182/blood.V128.22.3813.3813

Published: 2016

Journal Articles

Regulation of Elastase By SerpinA3N Contributes to Pain in Sickle Cell Disease

Anupam Aich, PhD, Jinny Paul, PhD, Jianxun Lei, PhD, Ying Wang, MD PhD, Anindya Bagchi, PhD, Kalpna Gupta, PhD

Blood (2016) 128 (22): 858.

https://doi.org/10.1182/blood.V128.22.858.858

Published: 2016

Journal Articles

Elevated Levels of Circulating Nucleosomes Are Not Associated with Venous Thrombosis or Neutrophil Activation in Patients with Multiple Myeloma

Mandy N. Lauw, MD PhD, Frank W.G. Leebeek, MD PhD, Moniek P.M. de Maat, PhD, Gerard J. van Mierlo, Saskia Middeldorp, MD PhD, Sacha S. Zeerleder, MD PhD

Blood (2016) 128 (22): 274.

https://doi.org/10.1182/blood.V128.22.274.274

Published: 2016

Journal Articles

Impaired Neutrophil Migration Resulting from Mir-34a and Mir-155 Overexpressed in Neutrophils from Myelodysplastic Syndrome Patients

Meiwan Cao, MD, Yayoi Shikama, MD PhD, Michiko Anzai, Junko Kimura, MD PhD

Blood (2015) 126 (23): 999.

https://doi.org/10.1182/blood.V126.23.999.999

Published: 2015

Journal Articles

Innate Immunity, Coagulation, and Thrombosis

Bernd Engelmann, MD PhD, Steffen Massberg, MD

Blood (2014) 124 (21): SCI-28.

https://doi.org/10.1182/blood.V124.21.SCI-28.SCI-28

Published: 2014

Journal Articles

Binding Of Immune Serine Proteases To Nucleic Acids Enhances Their Nuclear Localization and Promotes Their Cleavage Of Nucleic Acid-Binding Protein Substrates

Jennifer Whangbo, MD, PhD, Marshall Thomas, Geoffrey McCrossan, Aaron Deutsch, Kimberly Martinod, Michael Walch, MD, Judy Lieberman, MD, PhD

Blood (2013) 122 (21): 3471.

https://doi.org/10.1182/blood.V122.21.3471.3471

Published: 2013

Journal Articles

Neutrophil Extracellular Trap Formation In PNH Patients With and Without a History Of Thrombosis - Effects Of Eculizumab

Sacha Zeerleder, MD, PhD, Sandra van Bijnen, MD, Diana Wouters, PhD, Gerard J van Mierlo, Petra Muus, MD, PhD

Blood (2013) 122 (21): 1235.

https://doi.org/10.1182/blood.V122.21.1235.1235

Published: 2013

Journal Articles

Pegylated Versus Glycopegylated G-CSFs and Their Biochemical and Physiological Properties

Afsaneh Abdolzade-Bavil, Bridget A. Cooksey, Christian Scheckermann, Andreas Lammerich, Laurie Pukac, Philip Krasney, Hermann Allgaier, Wenyan David Shen, Udo Müller, Patrick Liu, Aaron von Kerczek

Blood (2013) 122 (21): 4851.

https://doi.org/10.1182/blood.V122.21.4851.4851

Published: 2013

Journal Articles

Myelopoiesis From Induced Pluripotent Stem Cells Reveals The Role Of Elastase Activity In The Pathogenesis Of Severe Congenital Neutropenia

Ramesh C Nayak, PH.D., Lisa Trump, PhD, H. Leighton Grimes, PhD, Carolyn Lutzko, PhD, Jose A. Cancelas, M.D. PhD.

Blood (2013) 122 (21): 442.

https://doi.org/10.1182/blood.V122.21.442.442

Published: 2013

Journal Articles

Deletion of OLFM4 Rescues Defective Host Defense Against Staphylococcus Aureus , but Not Aspergillus Fumigatus in Murine X-Linked Chronic Granulomatous Disease

Wenli Liu, MD, Janyce A Sugui, Hongzhen Li, Kyung J Kwon-Chung, Griffin P. Rodgers, MD

Blood (2012) 120 (21): 3276.

https://doi.org/10.1182/blood.V120.21.3276.3276

Published: 2012

Journal Articles

Biological Explanation of Clinically Observed Elevation of TFPI Plasma Levels After Treatment with TFPI-Antagonistic Aptamer BAX 499

Michael Dockal, PhD, Robert Pachlinger, Rudolf Hartmann, PhD, Sabine Knappe, PhD, Benny Sorensen, Wing Yen Wong, Maureen Conlan, Michael Cecerle, Bruce M. Ewenstein, MD PhD, Hartmut J. Ehrlich, MD, Friedrich Scheiflinger, PhD

Blood (2012) 120 (21): 1104.

https://doi.org/10.1182/blood.V120.21.1104.1104

Published: 2012

Journal Articles

Inactivation of Plasminogen Activator Inhibitor-1 by RNA Aptamer Molecules

Yolanda Fortenberry, PhD, Jared Damare

Blood (2012) 120 (21): 1107.

https://doi.org/10.1182/blood.V120.21.1107.1107

Published: 2012

Journal Articles

A Lack of Secretory Leukocyte Protease Inhibitor (SLPI) Causes Defects in Myeloid Differentiation

Olga Klimenkova, Wienke Ellerbeck, Ana Gigina, Karl Welte, MD, Julia Skokowa, MD, PhD

Blood (2012) 120 (21): 10.

https://doi.org/10.1182/blood.V120.21.10.10

Published: 2012

Journal Articles

Increased Circulating Nucleosomes and Neutrophil Activation As a Measure of the Formation of Neutrophil Extracellular Traps (NETs) During Sickle Cell Painful Crisis

Marein Schimmel, MD, Erfan Nur, MD, PhD, Sacha Zeerleder, MD PhD, Gerard J van Mierlo, Shabnam Solati, Dees P Brandjes, M.D., PhD, Hans-Martin Otten, MD, PhD, John-John Schnog, MD, PhD, Bart J Biemond, MD

Blood (2012) 120 (21): 821.

https://doi.org/10.1182/blood.V120.21.821.821

Published: 2012

Journal Articles

Variable Clinical Presentation of Shwachman-Diamond Syndrome: Update From the North-American Shwachman-Diamond Syndrome Registry.

Kasiani C. Myers, MD, Audrey Anna Bolyard, RN, BS, Barbara Otto, MS, BSN, Nicholas Dobbins, Amanda Jones, Trisha E. Wong, MD, Richard E. Harris, MD, Stella M. Davies, MBBS, PhD, David C. Dale, MD, Akiko Shimamura, MD, PhD

Blood (2012) 120 (21): 2367.

https://doi.org/10.1182/blood.V120.21.2367.2367

Published: 2012

NARROW

Design and characterization of α1-antitrypsin variants for treatment of contact system–driven thromboinflammation

Neutrophil Extracellular Traps Are an Intrinsic Feature in Sickle Cell Disease

Systemic Inflammation Induces Release of Cell-Free DNA from Hematopoietic and Parenchymal Cells in Mice and Human

Targeting Elastase with Alpha1 Anti-Trypsin Reduces Hyperalgesia in Mice with Sickle Cell Disease

Promyelocytic Extracellular Chromatin Exacerbates Coagulation Disorder in Acute Promyelocytic Leukemia

Canine Neutrophil Extracellular Traps Have Pro-Coagulant and Anti-Fibrinolytic Effects

Regulation of Elastase By SerpinA3N Contributes to Pain in Sickle Cell Disease

Elevated Levels of Circulating Nucleosomes Are Not Associated with Venous Thrombosis or Neutrophil Activation in Patients with Multiple Myeloma

Impaired Neutrophil Migration Resulting from Mir-34a and Mir-155 Overexpressed in Neutrophils from Myelodysplastic Syndrome Patients

Innate Immunity, Coagulation, and Thrombosis

Binding Of Immune Serine Proteases To Nucleic Acids Enhances Their Nuclear Localization and Promotes Their Cleavage Of Nucleic Acid-Binding Protein Substrates

Neutrophil Extracellular Trap Formation In PNH Patients With and Without a History Of Thrombosis - Effects Of Eculizumab

Pegylated Versus Glycopegylated G-CSFs and Their Biochemical and Physiological Properties

Myelopoiesis From Induced Pluripotent Stem Cells Reveals The Role Of Elastase Activity In The Pathogenesis Of Severe Congenital Neutropenia

Deletion of OLFM4 Rescues Defective Host Defense Against Staphylococcus Aureus , but Not Aspergillus Fumigatus in Murine X-Linked Chronic Granulomatous Disease

Biological Explanation of Clinically Observed Elevation of TFPI Plasma Levels After Treatment with TFPI-Antagonistic Aptamer BAX 499

Inactivation of Plasminogen Activator Inhibitor-1 by RNA Aptamer Molecules

A Lack of Secretory Leukocyte Protease Inhibitor (SLPI) Causes Defects in Myeloid Differentiation

Increased Circulating Nucleosomes and Neutrophil Activation As a Measure of the Formation of Neutrophil Extracellular Traps (NETs) During Sickle Cell Painful Crisis

Variable Clinical Presentation of Shwachman-Diamond Syndrome: Update From the North-American Shwachman-Diamond Syndrome Registry.

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American Society of Hematology

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American Society of Hematology

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