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Journal Articles

Hepcidin-Mediated Ferroportin Control in the Bone Marrow Is Dispensable

Katja Muedder, Bonadonna Michael, Bruno Galy, PhD, Martina U. Muckenthaler, PhD, Sandro Altamura, PhD

Blood (2019) 134 (Supplement_1): 3531.

https://doi.org/10.1182/blood-2019-126655

Published: 2019

Journal Articles

Sensing of Liver Iron Content Requires Cell-Cell Communication between Hepatocytes and Liver Sinusoidal Endothelial Cells

Silvia Colucci, Sandro Altamura, PhD, Matthias Hentze, Prof., Martina U. Muckenthaler, PhD

Blood (2019) 134 (Supplement_1): 432.

https://doi.org/10.1182/blood-2019-125586

Published: 2019

Journal Articles

Pre-Conditioning Serum Leptin Levels Predict Early Relapse Rates of High Risk AML after Allogeneic Stem Cell Transplantation

Mark-Alexander Schwarzbich, MD, Hao Dai, Lambros Kordelas, MD, Dietrich W. Beelen, Aleksandar Radujkovic, MD, Carsten Müller-Tidow, MD, Peter Dreger, MD, Thomas Luft, MD PhD

Blood (2018) 132 (Supplement 1): 3419.

https://doi.org/10.1182/blood-2018-99-112807

Published: 2018

Journal Articles

SLN124, a Galnac-siRNA Conjugate Targeting TMPRSS6, for the Treatment of Iron Overload and Ineffective Erythropoiesis Such As in Beta-Thalassemia

Sandro Altamura, PhD, Sandro Altamura, PhD, Martina U. Muckenthaler, PhD, Sibylle Dames, MSc, Christian Frauendorf, PhD, Steffen Schubert, PhD, Manuela Aleku, MSc, Jim Vadolas, PhD, George Grigoriadis, MBBS PhD FRACP FRCPA, Ulrich Zügel, PhD

Blood (2018) 132 (Supplement 1): 2340.

https://doi.org/10.1182/blood-2018-99-110163

Published: 2018

Journal Articles

TP-0184 Inhibits ALK2/ACVR1, Decreases Hepcidin Levels, and Demonstrates Activity in Preclinical Mouse Models of Functional Iron Deficiency

Peter Peterson, PhD, W K, Clifford Whatcott, PhD, Adam Siddiqui-Jain, PhD, Steven Weitman, MD PhD, Mark Kieran, MD PhD, David J. Bearss, PhD, Steven L. Warner, PhD

Blood (2017) 130 (Supplement 1): 937.

https://doi.org/10.1182/blood.V130.Suppl_1.937.937

Published: 2017

Journal Articles

Characterization of Iron Metabolism in Mouse Model of Congenital Polycythemia with Human Gain-of-Function Erythropoietin Receptor

Barbora Kralova, MSc, Jihyun Song, PhD, Vladimir Divoky, PhD, Josef T. Prchal, MD, Monika Horvathova, MSc, PhD

Blood (2017) 130 (Supplement 1): 170.

https://doi.org/10.1182/blood.V130.Suppl_1.170.170

Published: 2017

Journal Articles

Influential Role of Macrophages in Hepcidin Regulation in Apo-Transferrin Treated β-Thalassemic Mice

Daniel Moskop, Shuming Sun, PhD, Maria Feola, PhD, Marc Ruiz Martinez, PhD, Huiyong Chen, PhD, Jing Liu, PhD, Nathan Brinkman, PhD, Robert E Fleming, MD, Stefano Rivella, PhD, Yelena Ginzburg, MD

Blood (2017) 130 (Supplement 1): 172.

https://doi.org/10.1182/blood.V130.Suppl_1.172.172

Published: 2017

Journal Articles

Developing a Galnac-Conjugated TMPRSS6 Antisense Therapy for the Treatment of β-Thalassemia

Mariam Aghajan, PhD, Carla Casu, PhD, Vania lo Presti, Sheri Booten, Brett P. Monia, PhD, Stefano Rivella, PhD, Shuling Guo, PhD

Blood (2016) 128 (22): 1013.

https://doi.org/10.1182/blood.V128.22.1013.1013

Published: 2016

Journal Articles

The ALK-2 Inhibitor, TP-0184, Demonstrates High Distribution to the Liver Contributing to Significant Preclinical Efficacy in Mouse Models of Anemia of Chronic Disease

Peter Peterson, PhD, Wontak Kim, Hillary Haws, Clifford J. Whatcott, PhD, Adam Siddiqui-Jain, PhD, David J. Bearss, PhD, Steven L. Warner, PhD

Blood (2016) 128 (22): 263.

https://doi.org/10.1182/blood.V128.22.263.263

Published: 2016

Journal Articles

Validation of the Intrinsic Hepcidin IDx TM Test, an LDT for Clinical Hepcidin Assessment

Patrick Gutschow, MS, Keith Westerman, BS, Huiling Han, MD, Vaughn Ostland, PhD, Gordana Olbina, PhD, William Paxton, MD PhD, Mark Westerman, PhD

Blood (2016) 128 (22): 2456.

https://doi.org/10.1182/blood.V128.22.2456.2456

Published: 2016

Journal Articles

The Jak1/Jak2 Inhibitor Momelotinib Inhibits Alk2, Decreases Hepcidin Production and Ameliorates Anemia of Chronic Disease (ACD) in Rodents

Malte Asshoff, MD, Matthew Warr, PhD, David Haschka, MD, Piotr Tymoszuk, PhD, Verena Petzer, Egon Demetz, PhD, Pat Maciejewski, PhD, Markus Seifert, Manfred Nairz, MDPhD, Wilfried Posch, PhD, Peter Fowles, Guenter Weiss, MD, Andy Whitney, Igor Theurl, MDPhD

Blood (2015) 126 (23): 538.

https://doi.org/10.1182/blood.V126.23.538.538

Published: 2015

Journal Articles

Iron Age or New Age: Ironing out the Diagnosis of Anaemia of Inflammation from Iron Deficiency Anaemia

Nicola J Svenson, MSc, Undergraduate MSc Hons, Russell Patmore, MRCP FRCPath, Heidi J Cox, MBBS, MSc, MSc, BSc Hons, James R Bailey, MA MBBS MRCP, Stephen Holding, BSc, PhD FRCPath

Blood (2015) 126 (23): 3354.

https://doi.org/10.1182/blood.V126.23.3354.3354

Published: 2015

Journal Articles

The Role of Hepcidin in Health And Disease

Martina U. Muckenthaler, PhD

Blood (2015) 126 (23): SCI-43.

https://doi.org/10.1182/blood.V126.23.SCI-43.SCI-43

Published: 2015

Journal Articles

Targeting TMPRSS6 Using Antisense Technology for the Treatment of Beta-Thalassemia

Shuling Guo, PhD, Mariam Aghajan, PhD, Carla Casu, PhD, Sara Gardenghi, PhD, Sheri Booten, Stefano Rivella, PhD, Brett P. Monia, PhD

Blood (2015) 126 (23): 753.

https://doi.org/10.1182/blood.V126.23.753.753

Published: 2015

Journal Articles

Down-Regulation of TfR1 Increases Erythroid Precursor Enucleation and Hepatocyte Hepcidin Expression in ß-Thalassemic Mice

Huihui Li, MS, Tenzin Choesang, MS, Weili Bao, MS, Lionel Blanc, PhD, Huiyong Chen, PhD, Maria Feola, MS, Jie Li, MD, Guiyuan Li, MD, Shuming Sun, PhD, Antonia Follenzi, MDPhD, Petra Pham, MS, Xiuli An, MD PhD, Narla Mohandas, DSc, Robert E Fleming, MD, Stefano Rivella, PhD, Yelena Ginzburg, MD

Blood (2015) 126 (23): 754.

https://doi.org/10.1182/blood.V126.23.754.754

Published: 2015

Journal Articles

ALK2 Inhibition Via TP-0184 Abrogates Inflammation-Induced Hepcidin Expression and Is a Potential Therapeutic for Anemia of Chronic Disease

Peter Peterson, PhD, Katherine K. Soh, Ye Sol Lee, Wontak Kim, Clifford J. Whatcott, PhD, Adam Siddiqui-Jain, PhD, David J. Bearss, PhD, Steven L. Warner, PhD

Blood (2015) 126 (23): 273.

https://doi.org/10.1182/blood.V126.23.273.273

Published: 2015

Journal Articles

Hepcidin at the Nexus of Infection and Anemia

Hal Drakesmith, PhD

Blood (2014) 124 (21): SCI-39.

https://doi.org/10.1182/blood.V124.21.SCI-39.SCI-39

Published: 2014

Journal Articles

Dietary Supplementation with Ipriflavone Decreases Liver Iron Loading in Wild Type Mice

Bonnie Patchen, Vera Gaun, Aaron Cheng, Paula G. Fraenkel, MD

Blood (2014) 124 (21): 4025.

https://doi.org/10.1182/blood.V124.21.4025.4025

Published: 2014

Journal Articles

Hypoferremia of Fasting in Mice Is Associated with Increased Hepcidin and Decreased Erythroferrone Expression

Yihang Li, PhD, Gregory R Booth, MD, Qi Feng, MD, Robert E Fleming, MD

Blood (2014) 124 (21): 4026.

https://doi.org/10.1182/blood.V124.21.4026.4026

Published: 2014

Journal Articles

Reversibility of Iron Loading in Transferrin-Deficient Mice

Thomas Benedict Bartnikas, MDPhD

Blood (2014) 124 (21): 2679.

https://doi.org/10.1182/blood.V124.21.2679.2679

Published: 2014

NARROW

Hepcidin-Mediated Ferroportin Control in the Bone Marrow Is Dispensable

Sensing of Liver Iron Content Requires Cell-Cell Communication between Hepatocytes and Liver Sinusoidal Endothelial Cells

Pre-Conditioning Serum Leptin Levels Predict Early Relapse Rates of High Risk AML after Allogeneic Stem Cell Transplantation

SLN124, a Galnac-siRNA Conjugate Targeting TMPRSS6, for the Treatment of Iron Overload and Ineffective Erythropoiesis Such As in Beta-Thalassemia

TP-0184 Inhibits ALK2/ACVR1, Decreases Hepcidin Levels, and Demonstrates Activity in Preclinical Mouse Models of Functional Iron Deficiency

Characterization of Iron Metabolism in Mouse Model of Congenital Polycythemia with Human Gain-of-Function Erythropoietin Receptor

Influential Role of Macrophages in Hepcidin Regulation in Apo-Transferrin Treated β-Thalassemic Mice

Developing a Galnac-Conjugated TMPRSS6 Antisense Therapy for the Treatment of β-Thalassemia

The ALK-2 Inhibitor, TP-0184, Demonstrates High Distribution to the Liver Contributing to Significant Preclinical Efficacy in Mouse Models of Anemia of Chronic Disease

Validation of the Intrinsic Hepcidin IDx TM Test, an LDT for Clinical Hepcidin Assessment

The Jak1/Jak2 Inhibitor Momelotinib Inhibits Alk2, Decreases Hepcidin Production and Ameliorates Anemia of Chronic Disease (ACD) in Rodents

Iron Age or New Age: Ironing out the Diagnosis of Anaemia of Inflammation from Iron Deficiency Anaemia

The Role of Hepcidin in Health And Disease

Targeting TMPRSS6 Using Antisense Technology for the Treatment of Beta-Thalassemia

Down-Regulation of TfR1 Increases Erythroid Precursor Enucleation and Hepatocyte Hepcidin Expression in ß-Thalassemic Mice

ALK2 Inhibition Via TP-0184 Abrogates Inflammation-Induced Hepcidin Expression and Is a Potential Therapeutic for Anemia of Chronic Disease

Hepcidin at the Nexus of Infection and Anemia

Dietary Supplementation with Ipriflavone Decreases Liver Iron Loading in Wild Type Mice

Hypoferremia of Fasting in Mice Is Associated with Increased Hepcidin and Decreased Erythroferrone Expression

Reversibility of Iron Loading in Transferrin-Deficient Mice

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American Society of Hematology

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American Society of Hematology

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