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Journal Articles

GATA2 -Dependent Developmental and Regenerative Networks

Alexandra Soukup, PhD, Kirby D Johnson, PhD, Daniel J Conn, PhD, Evgenia Shishkova, PhD, Koichi Ricardo Katsumura, MD PhD, Peng Liu, PhD, Erik A. Ranheim, MD PhD, Katherine R. Calvo, MD PhD, Amy P. Hsu, Steven M. Holland, MD, Joshua J Coon, PhD, Sunduz Keles, PhD, Emery H Bresnick, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1182.
https://doi.org/10.1182/blood-2019-126875
Published: 2019
Journal Articles

Glia Maturation Factor-γ Regulates Autophagy in Murine Macrophages

Wulin Aerbajinai, MD PhD, Jianqiong Zhu, MD, Chutima Kumkhaek, PhD, Kyung Chin, Griffin Rodgers, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2318.
https://doi.org/10.1182/blood-2019-130318
Published: 2019
Journal Articles

Transcriptome Based Projection of Single Cells to Uncover Development and Heterogeneity of Abnormal Hematopoietic Cells

Parashar Dhapola, MSc, Mikael Sommarin, Mohamed Eldeeb, MSc, Amol Ugale, PhD, David Bryder, PhD, Göran Karlsson, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2520.
https://doi.org/10.1182/blood-2019-130587
Published: 2019
Journal Articles

The Condensin II Subunit, NcapH2, Is Required for Proper Embryonic Erythroid Terminal Maturation and Embryonic Viability in a Primary Mouse Model

Zachary C. Murphy, PhD, Michael Getman, MS, Laurie A. Steiner, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 153.
https://doi.org/10.1182/blood-2019-127353
Published: 2019
Journal Articles

Elucidating an Erythroblast Survival Mechanism: Differential Contributions of Exosome Complex Catalytic Subunits

Charu Mehta, MS, Isabela J Fraga de Andrade, Bachelors in Biological Science, Nobuyuki Tanimura, PhD, Gary M Wilson, Erik A. Ranheim, MD PhD, Joshua J Coon, PhD, Emery H Bresnick, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 155.
https://doi.org/10.1182/blood-2019-126917
Published: 2019
Journal Articles

Proteomic Landscape of Acute Leukemia: A Comparison between ALL and AML in Adults

Fieke W Hoff, BSc, Yihua Qiu, Wendy Hu, PhD, Amina A Qutub, PhD, Eveline S. de Bont, MD PhD, Terzah M Horton, MD PhD, Steven M. Kornblau, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1461.
https://doi.org/10.1182/blood-2019-123470
Published: 2019
Journal Articles

Pkcε Is a Central Regulator of Mitochondrial Function and Metabolism in Acute Myeloid Leukemia

Daniela Di Marcantonio, PhD, Elena Masselli, MD, Esteban Martinez, BS, Daniela Araiza-Olivera, MD PhD, Giuliana Gobbi, PhD, Prisco Mirandola, PhD, Marco Vitale, MD, Stephen M. Sykes, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3926.
https://doi.org/10.1182/blood-2018-99-119758
Published: 2018
Journal Articles

Synergistic Pre-Clinical Activity of Targeted Inhibition of KDM1A and BET Proteins Against Human AML Blast Progenitor Cells

Warren Fiskus, BSc, PhD, Christopher Peter Mill, PhD BA, Raffaella Soldi, Roulan Han, Dyana T. Saenz, PhD, Agnieszka J Nowak, Baohua Sun, MD PhD, David N Saenz, Courtney D. DiNardo, MD MSc, Gautam Borthakur, MD, Tapan M. Kadia, MD, Wendy Jin, Thurika Ganesh, Vaishnavi Rao, Joseph David Khoury, MD, Sunil Sharma, MD, Kapil N. Bhalla, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3930.
https://doi.org/10.1182/blood-2018-99-114198
Published: 2018
Journal Articles

Comprehensive Integrated Genomic Perturbations Reveal Molecular Mechanisms of Red Blood Cell Trait Associations

Yuxuan Wu, PhD, Mitchel A. Cole, BS, Abdou Mousas, Jing Zeng, MD, Qiuming Yao, PhD, Divya Vinjamur, PhD, Ryo Kurita, PhD, Yukio Nakamura, MD PhD, Luca Pinello, PhD, Guillame Lettre, PhD, Daniel E. Bauer, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 532.
https://doi.org/10.1182/blood-2018-99-120229
Published: 2018
Journal Articles

Dysregulation of RUNX3 in Aged Human HSPCs May Contribute to Perturbations in Erythropoiesis and Balanced Lineage Output

Peter Balogh, Brian Capaldo, PhD, Sandeep Singh, PhD, Kamaleldin Elagib, MBBS, PhD, Hui Li, PhD, Eli Zunder, PhD, Maria E. Figueroa, MD, Wendy Pang, MD, Adam Goldfarb, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2553.
https://doi.org/10.1182/blood-2018-99-115245
Published: 2018
Journal Articles

Functional and Molecular Consequences of Trisomy 21 on Human Fetal Hematopoiesis

Elvin Wagenblast, PhD, Gabriela Krivdova, BSc, MSc, Olga I. Gan, PhD, Johann K. Hitzler, MD, John E. Dick, PhD, Eric R. Lechman, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1317.
https://doi.org/10.1182/blood-2018-99-119734
Published: 2018
Journal Articles

Transcriptional Signaling Centers Govern Human Erythropoiesis and Harbor Genetic Variations of Red Blood Cell Traits

Avik Choudhuri, PhD, Eirini Trompouki, PhD, Brian J. Abraham, PhD, Leandro Colli, MD, William Mallard, Min-Lee Yang, PhD, Divya Vinjamur, PhD, Alireza Ghamari, PhD, Satish Nandakumar, PhD, Kanen Hoi, Barbara Hummel, Sonja Boatman, Victoria Chan, Teresa V. Bowman, PhD, Song Yang, Yi Zhou, Sinichiro Takahashi, MD PhD, Alan B. Cantor, MD PhD, Vijay G. Sankaran, MD PhD, Santhi Ganesh, MD, Daniel E. Bauer, MD PhD, John Rinn, PhD, Stephen J Chanock, MD, Richard A. Young, PhD, Leonard I. Zon, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1277.
https://doi.org/10.1182/blood-2018-99-118637
Published: 2018
Journal Articles

Specific Bone Marrow Mesenchymal Subsets in Patients with Myelodysplastic Syndromes Harbor Molecular Perturbations That Alter the Dynamics of Competition between Pre-Leukemic Clones and Normal Cells

Youmna Kfoury, PhD, Esha Jain, Jason R Myers, MS, Fei Ji, David B Sykes, MD PhD, Francois Mercier, MD FRCPC, Ani Papazian, BS, Cam Le, Mark A Randolph, M.A.Sc., David P. Steensma, MD, Omar I Abdel-Wahab, MD, Laura M. Calvi, MD, Ruslan I Sadreyev, PhD, Michael W. Becker, MD, David T. Scadden, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 938.
https://doi.org/10.1182/blood-2018-99-115242
Published: 2018
Journal Articles

Unbiased Profiling of the Immunomodulatory Properties of Soluble Proteins

Nikolaus Krall, PhD, Gregory Ian Vladimer, PhD, Berend Snijder, PhD, Noemi Meszaros, Nicole Müller-Sienerth, PhD, Gavin Wright, Giulio Superti-Furga, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2293.
https://doi.org/10.1182/blood.V130.Suppl_1.2293.2293
Published: 2017
Journal Articles

Spliceosomal Mutations Induce R Loop-Associated ATR Signaling

Wan Yee Leong, PhD, Hai Dang Nguyen, PhD, Weiling Li, PhD, Matthew J. Walter, MD, Lee Zou, PhD, Timothy A. Graubert, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 116.
https://doi.org/10.1182/blood.V130.Suppl_1.116.116
Published: 2017
Journal Articles

RNA-Sequencing of Isolated Cell Populations Expressing Human APOL1 Risk Variants Reveals Molecular Correlates of Sickle Cell Nephropathy in Zebrafish Podocytes

Joseph L Bundy, PhD BS, Blair R Anderson, PhD, Ludmila Francescatto, PhD, Melanie E Garrett, MS, Karen L Soldano, BS, Marilyn J. Telen, MD, Erica E Davis, PhD, Allison E Ashley-Koch, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2236.
https://doi.org/10.1182/blood.V130.Suppl_1.2236.2236
Published: 2017
Journal Articles

Distinct Signaling Centers Define Stages of Human Erythropoiesis and Harbor Common Variations of Red Blood Cell Traits

Avik Choudhuri, PhD, Eirini Trompouki, PhD, Brian J Abraham, PhD, William Mallard, Min-Lee Yang, PhD, Alireza Ghamari, PhD, Kanen Hoi, Barbara Hummel, Sonja Boatman, Victoria Chan, Teresa V. Bowman, PhD, Song Yang, Yi Zhou, Sinichiro Takahashi, MD PhD, Alan B. Cantor, MD, PhD, Santhi Ganesh, MD, John Rinn, PhD, Richard A. Young, PhD, Leonard I. Zon, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 773.
https://doi.org/10.1182/blood.V130.Suppl_1.773.773
Published: 2017
Journal Articles

Bromodomain Inhibition Is Effective Against Acute Myeloid Leukemia Cells Under Hypoxia and Induces Genome-Dependent Metabolic Perturbations

Giorgia Simonetti, PhD, Samantha Bruno, MSc, Carmine Onofrillo, PhD, Marco Malferrari, PhD, Cristina Papayannidis, MD PhD, Giovanni Marconi, MD, Michele Cavo, MD, Stefania Rapino, PhD, Lorenzo Montanaro, MD PhD, Giovanni Martinelli, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3936.
https://doi.org/10.1182/blood.V130.Suppl_1.3936.3936
Published: 2017
Journal Articles

Gaussian Mixture Models and Machine Learning Predict Megakaryocytic Growth and Differentiation Potential Ex Vivo

Jia J. Wu, BS, Darryl A. Abbott, BS, Meryem K. Terzioglu, MD, Dolores Mahmud, PhD, Nadim Mahmud, MBBS, PhD, William M. Miller, PhD, Neda Bagheri, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4474.
https://doi.org/10.1182/blood.V130.Suppl_1.4474.4474
Published: 2017
Journal Articles

Icare 1: A Prospective Clinical Trial to Predict Treatment Response Based on Mutanome-Informed Computational Biology in Patients with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS)

Leylah M. Drusbosky, PhD, Kimberly E. Hawkins, PhD BS, Cesia Salan, Madeleine Turcotte, MS, Glenda G. Anderson, Neeraj Kumar Singh, B.Tech, Saumya Radhakrishnan, BT, Yashaswini Ullal, BE, Anay Talawdekar, MT, Huzaifa Sikora, BT, Prashant Nair, BT, Priyanka Bhowmick, MS, Taher Abbasi, MS, MBA, Shireen Vali, PhD, Fei Zou, PhD, Nosha Farhadfar, MD, Hemant S. Murthy, MD, Biljana N. Horn, MD, Helen L. Leather, Paul Castillo, MD, Barry Sawicki, BS, Randy A. Brown, MD, Maxim Norkin, MD, John W. Hiemenz, MD, Jack W. Hsu, MD, William Slayton, MD, John R. Wingard, MD, Christopher R. Cogle, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4277.
https://doi.org/10.1182/blood.V130.Suppl_1.4277.4277
Published: 2017