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Journal Articles

Targeting T-ALL Cells with Potent Activators of the PP2A Protein Phosphatase Tumor Suppressor

Ken Morita, MD PhD, Shuning He, PhD, Radosław P. Nowak, PhD, Jinhua Wang, PhD, Nathanael Gray, PhD, Eric S. Fischer, PhD, A. Thomas Look, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 406.
https://doi.org/10.1182/blood-2019-123573
Published: 2019
Journal Articles

IKZF1 Regulates BRD4 Retention and Recruitement at Enhancer in Myeloma Cells: Role of BRD4 in IMiDs Resistance

Paola Neri, MD PhD, Ines Tagoug, PhD, Ranjan Maity, PhD, Jacquelyn Babich, Lindsay Lockwood, Jonathan J Keats, PhD, Larry H Boise, PhD, Leif Bergsagel, MD, Nizar J. Bahlis, MD
Journal: Blood
Blood (2016) 128 (22): 358.
https://doi.org/10.1182/blood.V128.22.358.358
Published: 2016
Journal Articles

Thioridazine Enhances TRAIL Cytotoxicity in Human Myeloid Leukemic Cells By up-Regulating DR5 and Modulating PI3K-AKT-NF-Kb Pathway

Yi Wang, Yangyi Bao, Leiming Xia, Liu Liu, Kunyuan Guo, Mingzhen Yang, MDPhD
Journal: Blood
Blood (2015) 126 (23): 4938.
https://doi.org/10.1182/blood.V126.23.4938.4938
Published: 2015
Journal Articles

Synergistic Targeting of Protein Translation and Inhibition of NOTCH Signaling in T-ALL

Marta Sanchez-Martin, PhD, Alberto Ambesi-Impiombato, MDPhD, Luyao Xu, Yue Qin, Daniel Herranz, PhD, Mukesh Bansal, PhD, Tiziana Girardi, Kim De Keersmaecker, Andrea Califano, PhD, Adolfo A. Ferrando, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3719.
https://doi.org/10.1182/blood.V126.23.3719.3719
Published: 2015
Journal Articles

PI3K/AKT/mTOR Signaling Is a Significant Druggable Pathway In Infant Acute Lymphoblastic Leukemia (ALL)

Karen A. Urtishak, PhD, Wang Li-San, PhD, David T. Teachey, MD, Tasian K. Sarah, MD, Jeffrey S. Barrett, PhD, I-Ming L. Chen, Susan R. Atlas, PhD, Richard C. Harvey, PhD, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Stephen P. Hunger, MD, Cheryl L. Willman, MD, Carolyn A. Felix, MD
Journal: Blood
Blood (2013) 122 (21): 1669.
https://doi.org/10.1182/blood.V122.21.1669.1669
Published: 2013
Journal Articles

Phenothiazines Induce Apoptosis in T-Cell Acute Lymphoblastic Leukemia by Activating the Phosphatase Activity of the PP2A Tumor Suppressor

Alejandro Gutierrez, MD, Alex Kentsis, MD, PhD, Li Pan, PhD, Frederic Baleydier, M.D Ph.D, Jason Marineau, PhD, Ruta Grebliunaite, Elena Kozakewich, Casie Reed, BS, Francoise Pflumio, Sandrine Poglio, Benjamin Uzan, Paul A. Clemons, Lynn VerPlank, W. Frank An, Jason Burbank, Stephanie Norton, Nicola J Tolliday, PhD, Hanno Steen, PhD, James E Bradner, MD, A. Thomas Look, M.D., Jon C Aster, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3558.
https://doi.org/10.1182/blood.V120.21.3558.3558
Published: 2012
Journal Articles

Aggressive Electrolytes Replacement in Multiple Myeloma (MM) Patients Receiving Arsenic Trioxide (ATO) Containing Regimens Alleviates the Need for Frequent Electrocardiogram (ECG) Monitoring.

Toni K. Choueiri, MD, Esteban Walker, PhD, Rachid C. Baz, MD, Rony M. Abou-Jawde, MD, Snehal G. Thakkar, MD, Bridget McGowan, Megan Kelly, Steven Andresen, MD, Mohamad Hussein, MD
Journal: Blood
Blood (2005) 106 (11): 5155.
https://doi.org/10.1182/blood.V106.11.5155.5155
Published: 2005