1-20 of 84
polyribosomes
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Pharmacological Inhibition of the RNA m 6 a Writer METTL3 As a Novel Therapeutic Strategy for Acute Myeloid Leukemia

Konstantinos Tzelepis, Etienne De Braekeleer, PhD MSc, Eliza Yankova, PhD, Justyna Rak, PhD, Demetrios Aspris, MSc, Ana Filipa Domingues, PhD, Richard Fosbeary, Alan Hendrick, PhD, Dan Leggate, PhD, Yaara Ofir-Rosenfeld, PhD, Alexandra Sapetschnig, PhD, Cristina Pina, MDDPhil, Mark Albertella, PhD, Wesley Blackaby, PhD, Oliver Rausch, PhD, George S. Vassiliou, FRCPath, MRCP, PhD, Tony Kouzarides, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 403.
https://doi.org/10.1182/blood-2019-127962
Published: 2019
Journal Articles

CircPCMTD1 : A Protein-Coding Circular RNA That Regulates DNA Synthesis in Leukemic Myeloblasts

Dimitrios Papaioannou, MD, Remi Buisson, Andreas Petri, PhD, Allison Walker, Marius Bill, MD PhD, Felice Pepe, PhD, Deedra Nicolet, MS, Lauren A Woodward, Krzysztof Mrózek, MD PhD, Malith Karunasiri, Gregory K. Behbehani, MD PhD, Emanuele Cocucci, PhD, Guramrit Singh, PhD, Sakari Kauppinen, PhD, Adrienne M. Dorrance, PhD, Clara D. Bloomfield, MD, Ramiro Garzon, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 640.
https://doi.org/10.1182/blood-2019-126223
Published: 2019
Journal Articles

Targeting eIF4A Using MZ-735 Potently Induces Cell Death in Lymphoma Cells and Rapidly Represses mRNA Translation at the Global Level and in C-MYC and Other Oncogenes

Ipsita Pal, PhD, Yu Ri Kim, MD, Sohani Das Sharma, PhD, Prabhjot S. Mundi, MD, Andre M. Grilo, PhD, Luke E Berchowitz, PhD, Mingzhao Zhu, PhD, Hull G. Kenneth, PhD, Daniel Romo, PhD, Owen O'Connor, MD PhD, Marko Jovanovic, PhD, Changchun Deng, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4067.
https://doi.org/10.1182/blood-2019-131816
Published: 2019
Journal Articles

Casein Kinase 1 Delta Is a Novel Regulator of mRNA Translation and Druggable Target in Aggressive Lymphomas

Ipsita Pal, PhD, Sohani Das Sharma, PhD, Andre M. Grilo, PhD, Prabhjot S. Mundi, MD, Luigi Scotto, PhD, Abdullah Mahmood Ali, PhD, Luke E Berchowitz, PhD, Siddhartha Mukherjee, MD PhD, Owen O'Connor, MD PhD, Marko Jovanovic, PhD, Changchun Deng, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2864.
https://doi.org/10.1182/blood-2019-129528
Published: 2019
Journal Articles

Expression of Human SBDS R126T in S bds Null Background Shows Eif6 Dysregulation: An Adult Zebrafish Model for Shwachman-Diamond Syndrome

Usua Oyarbide Cuervas-Mons, PhD MSc, BSc, Matthew Snyderman, MSc, Jacek Topczewski, PhD, Seth J. Corey, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3737.
https://doi.org/10.1182/blood-2019-129014
Published: 2019
Journal Articles

Mutation of Murine Rpl5 reveals a New Model for Diamond Blackfan Anemia Characterized By Defective Erythropoiesis

Philippe Lemay, PhD, Morgan A Jones, MD PhD BS, MS, Fatma Mohamed, Marie-Claude Guyot, Alexander Ludlow, Qing Li, MD, James Douglas Engel, PhD, Renny Franceschi, PhD, Thomas L. Rothstein, MD PhD, Vesa Kaartinen, PhD, Zoha Kibar, PhD, Sharon A Singh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2495.
https://doi.org/10.1182/blood-2019-131526
Published: 2019
Journal Articles

Disease Modeling and Phenotype Rescue Using Inducible Pluripotent Stem Cells from Patients with Diamond-Blackfan Anemia

Senthil Velan Bhoopalan, MD PhD, Min-Joon Han, PhD, Steven Ellis, PhD, Harry Lesmana, MD, Jeremie H. Estepp, MD, Yoonjeong Jang, DVM,PhD, Mitchell J. Weiss, MD PhD, Marcin W. Wlodarski, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2496.
https://doi.org/10.1182/blood-2019-131354
Published: 2019
Journal Articles

The Inherited MDS Gene DDX41 Is Required for Ribosome Biogenesis and Cell Viability

Timothy M Chlon, PhD, Emily Stepanchick, Kwangmin Choi, PhD, Yi Zheng, PhD, Kathleen Hueneman, Ashley Davis, Daniel T. Starczynowski, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 773.
https://doi.org/10.1182/blood-2019-127471
Published: 2019
Journal Articles

Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells

Harold K. Elias, MD, Christina Spevak, PhD, Lavanya Kannan, PhD, Mohamed A.E. Ali, MD PhD, Gaelle H Martin, PhD, Shanmugapriya Selvaraj, MS, William S Eng, Guangjie Zhao, BS, Amanda Ernlund, PhD, Vinagolu Rajasekhar, PhD, Carolien M Woolthuis, MD PhD, Robert J Schneider, PhD, Christopher Y. Park, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1180.
https://doi.org/10.1182/blood-2019-131333
Published: 2019
Journal Articles

Eltrombopag Improves Erythroid Differentiation in a Human iPSC Model of Diamond Blackfan Anemia

Husam Qanash, MSc, Kaari Linask, Jeanette Beers, Keyvan Keyvanfar, Sara Young-Baird, Waleed Hakami, Richard H. Smith, Jizhong Zou, Andre Larochelle, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1214.
https://doi.org/10.1182/blood-2019-121822
Published: 2019
Journal Articles

Control of Human Hemoglobin Switching By LIN28B-Mediated Regulation of BCL11A Translation

Anindita Basak, PhD, Mathias Munschauer, PhD, Jacob C. Ulirsch, BS, Kara E. Montbleau, Christina R. Hartigan, BS, Monica Schenone, PhD, John Lian, PhD, Yaomei Wang, Yumin Huang, Xianfang Wu, Lee Gehrke, Charles M. Rice, Xiuli An, MD PhD, Helen A. Christou, Mohandas Narla, DSc, Steven A. Carr, PhD, Stuart H. Orkin, MD, Jane-Jane Chen, PhD, Eric S. Lander, Vijay G. Sankaran, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 412.
https://doi.org/10.1182/blood-2018-99-117440
Published: 2018
Journal Articles

Small-Molecule Inhibition of PRMT5 Induces Translational Stress and p53 in JAK2V617F Mutant Myeloproliferative Neoplasms

Stefan Sonderegger, PhD MSc, Loretta Cerruti, BSc, Cedric Tremblay, PhD, Emma Toulmin, PhD, Jesslyn Saw, BSc, Tom Nebl, PhD, Katherine M Hannan, PhD, Steven W. Lane, MD PhD, Hendrik Falk, PhD, Ashwin Unnikrishnan, PhD, Paul Stupple, PhD, Ian Street, PhD, Stephen Jane, MDPhD, Rachel Altura, PhD, Benjamin Nicholson, PhD, David J. Curtis, MBBS,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 53.
https://doi.org/10.1182/blood-2018-99-118406
Published: 2018
Journal Articles

Mtor-Independent Translation in Early Hematopoietic Development

Christina Spevak, PhD, Harold Elias, MD, Lavanya Kannan, PhD, Gaelle Martin, PhD, Shanmugapriya Selvaraj, William Eng, Amanda Ernlund, Vinagolu Rajasekhar, PhD, Carolien Woolthuis, MD PhD, Robert Schneider, PhD, Christopher Y. Park, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3827.
https://doi.org/10.1182/blood-2018-99-120191
Published: 2018
Journal Articles

Alternative Overexpression of NRF2 or MYC Defines a Subgroup of Poor Prognosis Acute Myeloid Leukemia and Suggests a Novel Therapeutic Strategy By Combined Bromodomain Inhibition and Forced NRF2 Pathway Activation

Giorgia Simonetti, PhD, Samantha Bruno, Carmine Onofrillo, PhD, Cristina Papayannidis, Giovanni Marconi, Michele Cavo, MD, Lorenzo Montanaro, MD PhD, Giovanni Martinelli
Journal: Blood
Blood (2018) 132 (Supplement 1): 2639.
https://doi.org/10.1182/blood-2018-99-117429
Published: 2018
Journal Articles

hnRNP K: A Regulator of Global Transcription and Translation That Drives Lymphomagenesis

Prerna Malaney, PhD, Miguel Gallardo, PhD, Marisa J Hornbaker, BS, Xiaorui Zhang, BS, Todd Link, PhD, Vrutant Shah, PhD, Sanzhar Alybayev, MS, Meng-Han Wu, Laura R Pageon, DVM, Huaxian Ma, MS, Rodrigo Jacamo, PhD, Li Yu, MD, Zijun Yidan Xu-Monette, PhD, Haley Steinman, BS, Hun Ju Lee, MD, Dos Sarbassov, PhD, Inmaculada Rapado, Michelle Barton, PhD, Joaquin Martinez-Lopez, MDPhD, Carlos E. Bueso-Ramos, MD PhD, Ken H. Young, MD PhD, Sean M Post, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1346.
https://doi.org/10.1182/blood-2018-99-116163
Published: 2018
Journal Articles

Bromodomain Inhibition Is Effective Against Acute Myeloid Leukemia Cells Under Hypoxia and Induces Genome-Dependent Metabolic Perturbations

Giorgia Simonetti, PhD, Samantha Bruno, MSc, Carmine Onofrillo, PhD, Marco Malferrari, PhD, Cristina Papayannidis, MD PhD, Giovanni Marconi, MD, Michele Cavo, MD, Stefania Rapino, PhD, Lorenzo Montanaro, MD PhD, Giovanni Martinelli, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3936.
https://doi.org/10.1182/blood.V130.Suppl_1.3936.3936
Published: 2017
Journal Articles

CD99 Regulates Normal and Malignant Stem Cell Function By Restricting Protein Translation

Stephen S. Chung, MD, Wenhuo Hu, PhD, Liang Guo, PhD, Lavanya Kannan, PhD, Ross L. Levine, MD, Christopher Y. Park, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3749.
https://doi.org/10.1182/blood.V130.Suppl_1.3749.3749
Published: 2017
Journal Articles

The Marine Natural Compound Elatol Is a Novel Protein Translation Inhibitor with Potent Activity Against Aggressive Non-Hodgkin Lymphomas

Tara Peters, BA, Joseph Tillotson, PhD, Sarah C Wilmore, BSc, Alison Yeomans, PhD, Graham Packham, PhD, Eli Chapman, PhD, Jonathan H. Schatz, MD, Lingxiao Li, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4112.
https://doi.org/10.1182/blood.V130.Suppl_1.4112.4112
Published: 2017
Journal Articles

Fetal Erythropoiesis Is Defective in Rpl11 Heterozygous Mice and Increases in Severity in Young Animals

Dolly Thomas, PhD, Cailin Joyce, PhD, Robert A. Redd, MS, Bertil Glader, MD, Steven Ellis, PhD, Donna S. Neuberg, ScD, Meaghan McGuinness, BS, Colin A. Sieff, MB, BCh, Carl D. Novina, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 872.
https://doi.org/10.1182/blood.V130.Suppl_1.872.872
Published: 2017
Journal Articles

Ribosome Biogenesis Controls Erythroid Differentiation Via a p53-Dependent Transcriptional Checkpoint and Its Limitation By RPS14 Haploinsufficiency Results in Selective Defects in Translation

Ismael Boussaid, PharmD, Salome Le Goff, PhDstudent, Celia Floquet, Post-doc, Anna Raimbault, PharmD, PhD, Charlotte Andrieu-Soler, Emilie-fleur Gautier, PhD, Olivier Kosmider, Isabelle Hatin, PhD, Mohandas Narla, DSc, Eric Soler, PhD, Patrick Mayeux, PhD, Michaela Fontenay, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 83.
https://doi.org/10.1182/blood.V130.Suppl_1.83.83
Published: 2017