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Journal Articles

Proteomic Profiling and Mechanistic Investigating of a Novel Anti-Cancer Small Molecule Inhibitor of Sec61

Yu Qian, PhD, Henry W.B. Johnson, PhD, Christopher J. Kirk, PhD, Eric Lowe, BS, Dustin McMinn, PhD, Beatriz Millare, BS, Tony Muchamuel, MS, Jinhai Wang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2076.
https://doi.org/10.1182/blood-2019-125988
Published: 2019
Journal Articles

Restore the Secretion and Activity of Factor VIII Mutants By Proteostasis Regulator

Wei Wei, MD PhD, Zhigang Liu, PhD, Bin Zhang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1104.
https://doi.org/10.1182/blood-2019-129156
Published: 2019
Journal Articles

Protein Phase Separation in Hematopoietic Stem Cell Aging

Laure Maneix, PhD, Polina Iakova, M.S., Shannon Moree, B.A., Melanie Sweeney, B.A., Nagaishwarya Moka, MD, Sarvari Venkata Yellapragada, MD, Andre Catic, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5003.
https://doi.org/10.1182/blood-2019-124092
Published: 2019
Journal Articles

Proteostasis and Myeloid Stem Cell Production

Robert Signer, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-42.
https://doi.org/10.1182/blood-2019-121085
Published: 2019
Journal Articles

Targeting AML: The Development of Two Functionally and Mechanistically Distinct Classes of Cereblon-Mediated Protein Homeostatic Modulators

Aparajita Hoskote Chourasia, PhD, Leah Fung, PhD, Brooke McElwee, BSc, Normand Richard, MSc, Imelda Lam, BSc, Eduardo Torres, MSc, Paul Erdman, MSc, Robert Sullivan, PhD, David Hecht, PhD, Kyle WH Chan, PhD, Frank Mercurio, PhD, David I Stirling, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3361.
https://doi.org/10.1182/blood-2019-131872
Published: 2019
Journal Articles

Novel Allosteric Inhibitors of Heat Shock Protein 70 As Agents to Probe Protein Homeostasis and Overcome Proteasome Inhibitor Resistance in Multiple Myeloma

Ian Ferguson, BA, Christine Lam, BA, Margarette C. Mariano, MS, Donghui Wang, BA, Paul Phojanakong, BA, Sami Toumivaara, PhD, Hao Shao, PhD, Byron C Hann, MD PhD, Jason Gestwicki, PhD, Arun P Wiita, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3212.
https://doi.org/10.1182/blood-2018-99-117401
Published: 2018
Journal Articles

Remodeling of the malaria parasite and host human red cell by vesicle amplification that induces artemisinin resistance

Souvik Bhattacharjee, Isabelle Coppens, Alassane Mbengue, Niraja Suresh, Mehdi Ghorbal, Zdenek Slouka, Innocent Safeukui, Hsin-Yao Tang, David W. Speicher, Robert V. Stahelin, Narla Mohandas, Kasturi Haldar
Journal: Blood
Blood (2018) 131 (11): 1234–1247.
https://doi.org/10.1182/blood-2017-11-814665
Published: 2018
Includes: Supplemental data
Journal Articles

Protein Homeostasis: A Key Target in Myeloma

Lawrence H. Boise, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): SCI-8.
https://doi.org/10.1182/blood.V130.Suppl_1.SCI-8.SCI-8
Published: 2017
Journal Articles

N-RasG12D-Mediated Dysregulation of IRE1alpha-Xbp1s Signaling Promotes Pre-Leukemic Hematopoietic Stem Cell Expansion

Lu Liu, PhD, Meiling Zhao, MS, Kevin B Yang, Xi Jin, PhD, Gina Ney, MD PhD, Juan Del Valle, BS, PhD, Takao Iwawaki, PhD, Qing Li, MD PhD
Journal: Blood
Blood (2016) 128 (22): 567.
https://doi.org/10.1182/blood.V128.22.567.567
Published: 2016
Journal Articles

Assessing Proteostasis and Proteasome Stress In Light Chain Amyloidosis

Laura Oliva, PhD, Giovanni Palladini, MD, Fulvia Cerruti, PhD, Niccolò Pengo, MS, Paolo Cascio, PhD, Giampaolo Merlini, MD, Roberto Sitia, MD, Simone Cenci, MD
Journal: Blood
Blood (2010) 116 (21): 3992.
https://doi.org/10.1182/blood.V116.21.3992.3992
Published: 2010