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Journal Articles

A Meta-Analysis Evaluating the Risk of Bleeding-Related Adverse Events with Defibrotide Treatment

William Tappe, Saurabh Aggarwal, Ozlem Topaloglu, Massimo Iacobelli

Blood (2019) 134 (Supplement_1): 2016.

https://doi.org/10.1182/blood-2019-123686

Published: 2019

Journal Articles

Treatment of Primary Plasma Cell Leukemia with Carfilzomib and Lenalidomide-Based Therapy: Results of the First Interim Analysis of the Phase 2 EMN12/HOVON129 Study

Blood (2019) 134 (Supplement_1): 693.

https://doi.org/10.1182/blood-2019-125120

Published: 2019

Journal Articles

Veno-Occlusive Disease (VOD) after Hematopoietic Stem Cell Transplant (HSCR): Always a Catastrophic Illness?

Paolo Bernasconi, MD, Anna Amelia Colombo, MD, Daniela Caldera, MD, Oscar Borsani, MD

Blood (2019) 134 (Supplement_1): 5649.

https://doi.org/10.1182/blood-2019-125608

Published: 2019

Journal Articles

Study Design of an Open-Label, Single-Arm, Multicenter, Phase 2 Study to Evaluate the Safety and Efficacy of Defibrotide in Adult Patients with Transplant-Associated Thrombotic Microangiopathy

Vincent T. Ho, Nino Keshelava, Suzanne Swann, William Tappe

Blood (2019) 134 (Supplement_1): 3257.

https://doi.org/10.1182/blood-2019-123520

Published: 2019

Journal Articles

Cost-Effectiveness of Defibrotide for the Treatment of Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) with Multi-Organ Dysfunction (MOD) Post-Hematopoietic Stem Cell Transplantation (HSCT) in Canada

Jonathan Belsey, Eric Ngonga Kemadjou, Maya Isaila, Kathleen F. Villa

Blood (2018) 132 (Supplement 1): 4702.

https://doi.org/10.1182/blood-2018-99-111396

Published: 2018

Journal Articles

Incidence of Post-Hematopoietic Stem Cell Transplantation (HSCT) Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) without Hyperbilirubinemia at Diagnosis and Efficacy of Defibrotide in an Expanded-Access Program

Selim Corbacioglu, MD, Nancy A. Kernan, Antonio Pagliuca, Robert Ryan, William Tappe, Paul Richardson

Blood (2018) 132 (Supplement 1): 2080.

https://doi.org/10.1182/blood-2018-99-117173

Published: 2018

Journal Articles

A Pooled Analysis of Survival By Defibrotide Timing of Initiation in Adults with Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Following Hematopoietic Stem Cell Transplant (HSCT)

Paul Richardson, Enric Carreras, Antonio Pagliuca, Robert Ryan, William Tappe, Mohamad Mohty, MD PhD

Blood (2018) 132 (Supplement 1): 815.

https://doi.org/10.1182/blood-2018-99-113099

Published: 2018

Journal Articles

Outcomes within Five Years from Diagnosis in Pediatric Hodgkin Lymphoma Patients Following Contemporary Therapy

Karen E Effinger, MD MS, John Bergsagel, MD, Taylor Lawrence, Frank G Keller, MD, Rebecca Williamson Lewis, MPH, Lillian Meacham, MD, Ann Mertens, PhD, Sharon M. Castellino, MD MSc

Blood (2017) 130 (Supplement 1): 3466.

https://doi.org/10.1182/blood.V130.Suppl_1.3466.3466

Published: 2017

Journal Articles

Final Analysis of Day +100 Survival By Prior Hematopoietic Stem Cell Transplant Type from an Expanded Access Study of Defibrotide for Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome

Paul G Richardson, MD, Angela R. Smith, MD MS, Brandon Triplett, MD, Nancy Kernan, MD, Leslie Lehmann, MD, Robert J. Ryan, Robin L. Hume, MS, William Martin Tappe, MD, Stephan A Grupp, MD PhD

Blood (2017) 130 (Supplement 1): 3224.

https://doi.org/10.1182/blood.V130.Suppl_1.3224.3224

Published: 2017

Journal Articles

Adults Receiving Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Stem Cell Transplantation (HSCT): Final Results from the Expanded-Access Program

Paul G Richardson, MD, Joseph H. Antin, MD, Sergio A. Giralt, MD, Robert J. Ryan, Wei Liang, Robin L. Hume, MS, William Martin Tappe, MD, Nancy A. Kernan, MD

Blood (2017) 130 (Supplement 1): 3225.

https://doi.org/10.1182/blood.V130.Suppl_1.3225.3225

Published: 2017

Journal Articles

Timing of Diagnosis and Severity of Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) at Diagnosis after Hematopoietic Stem Cell Transplantation: Results from a Retrospective Chart Review

Kathy Del Pino, Nathan Rustay, PhD, Kira Mamedov, MD

Blood (2017) 130 (Supplement 1): 5462.

https://doi.org/10.1182/blood.V130.Suppl_1.5462.5462

Published: 2017

Journal Articles

Pooled Analysis of Defibrotide Studies in the Treatment of Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Stem Cell Transplantation (HSCT) or Chemotherapy without HSCT

Paul G Richardson, MD, Saurabh Aggarwal, Ozlem Topaloglu, Kathleen Villa, MS, Selim Corbacioglu, MD PhD

Blood (2017) 130 (Supplement 1): 5467.

https://doi.org/10.1182/blood.V130.Suppl_1.5467.5467

Published: 2017

Journal Articles

Timing of Defibrotide Initiation in Patients with Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) and Multi-Organ Dysfunction (MOD) after Hematopoietic Stem Cell Transplantation (HSCT): Results from a Retrospective Chart Review

Kathy Del Pino, Nathan Rustay, PhD, Kira Mamedov, MD

Blood (2017) 130 (Supplement 1): 5461.

https://doi.org/10.1182/blood.V130.Suppl_1.5461.5461

Published: 2017

Journal Articles

Successful MPB Therapy Followed By Bortezomib Maintenance for Non-Transplant Eligible Patients with Newly Diagnosed Multiple Myeloma: Japanese Phase 2 Study - Broad-J Study

Blood (2017) 130 (Supplement 1): 5432.

https://doi.org/10.1182/blood.V130.Suppl_1.5432.5432

Published: 2017

Journal Articles

Pooled Analysis of Day +100 Survival for Defibrotide-Treated Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) and Ventilator or Dialysis Dependence Following Hematopoietic Stem Cell Transplantation (HSCT)

Paul G Richardson, MD, Angela R. Smith, MD MS, Nancy A. Kernan, MD, Joseph H. Antin, MD, Leslie Lehmann, MD, Robert J. Ryan, Robin L. Hume, MS, William Martin Tappe, MD, Stephan A Grupp, MD PhD

Blood (2017) 130 (Supplement 1): 1946.

https://doi.org/10.1182/blood.V130.Suppl_1.1946.1946

Published: 2017

Journal Articles

Efficacy and Safety of Defibrotide in Pediatric Patients with Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Stem Cell Transplantation (HSCT): Final Results from the Expanded-Access Program

Nancy A. Kernan, MD, Angela R. Smith, MD MS, Brandon Triplett, MD, Leslie Lehmann, MD, Robert J. Ryan, Wei Liang, Robin L. Hume, MS, William Martin Tappe, MD, Stephan A Grupp, MD PhD

Blood (2017) 130 (Supplement 1): 1948.

https://doi.org/10.1182/blood.V130.Suppl_1.1948.1948

Published: 2017

Journal Articles

Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Post-Hematopoietic Stem Cell Transplantation (HSCT) in Patients with Neuroblastoma: Final Data from the Defibrotide Expanded-Access Program

Stephan A Grupp, MD PhD, Brandon Triplett, MD, Araz Marachelian, MD, Sonata Jodele, MD, Robert J. Ryan, Robin L. Hume, MS, William Martin Tappe, MD, Paul G Richardson, MD

Blood (2017) 130 (Supplement 1): 4549.

https://doi.org/10.1182/blood.V130.Suppl_1.4549.4549

Published: 2017

Journal Articles

Impact on Outcomes of Baseline Bilirubin in Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Receiving Defibrotide Treatment: A Post-Hoc Analysis

Paul G. Richardson, MD, Angela R. Smith, MD, Brandon M. Triplett, MD, Nancy A. Kernan, MD, Stephan A. Grupp, MD PhD, Joseph H. Antin, MD, Leslie Lehmann, MD, Wei Liang, PhD, Robin Hume, MS, William Tappe, MD, Robert J. Soiffer, MD

Blood (2016) 128 (22): 2213.

https://doi.org/10.1182/blood.V128.22.2213.2213

Published: 2016

Journal Articles

Timing of Initiation of Defibrotide Post-Diagnosis of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Post-Hematopoietic Stem Cell Transplantation: Exploratory Age-Group Analysis from an Expanded Access Study

Stephan A. Grupp, MD PhD, Angela R. Smith, MD, Brandon M. Triplett, MD, Nancy A. Kernan, MD, Joseph H. Antin, MD, Leslie Lehmann, MD, Wei Liang, PhD, Robin Hume, MS, William Tappe, MD, Paul G. Richardson, MD

Blood (2016) 128 (22): 66.

https://doi.org/10.1182/blood.V128.22.66.66

Published: 2016

Journal Articles

Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Post-Hematopoietic Stem Cell Transplantation (HSCT) in Patients with Acute Leukemias: A Subgroup Analysis from the Defibrotide Expanded-Access Program

Blood (2016) 128 (22): 3412.

https://doi.org/10.1182/blood.V128.22.3412.3412

Published: 2016

NARROW

A Meta-Analysis Evaluating the Risk of Bleeding-Related Adverse Events with Defibrotide Treatment

Treatment of Primary Plasma Cell Leukemia with Carfilzomib and Lenalidomide-Based Therapy: Results of the First Interim Analysis of the Phase 2 EMN12/HOVON129 Study

Veno-Occlusive Disease (VOD) after Hematopoietic Stem Cell Transplant (HSCR): Always a Catastrophic Illness?

Study Design of an Open-Label, Single-Arm, Multicenter, Phase 2 Study to Evaluate the Safety and Efficacy of Defibrotide in Adult Patients with Transplant-Associated Thrombotic Microangiopathy

Cost-Effectiveness of Defibrotide for the Treatment of Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) with Multi-Organ Dysfunction (MOD) Post-Hematopoietic Stem Cell Transplantation (HSCT) in Canada

Incidence of Post-Hematopoietic Stem Cell Transplantation (HSCT) Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) without Hyperbilirubinemia at Diagnosis and Efficacy of Defibrotide in an Expanded-Access Program

A Pooled Analysis of Survival By Defibrotide Timing of Initiation in Adults with Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Following Hematopoietic Stem Cell Transplant (HSCT)

Outcomes within Five Years from Diagnosis in Pediatric Hodgkin Lymphoma Patients Following Contemporary Therapy

Final Analysis of Day +100 Survival By Prior Hematopoietic Stem Cell Transplant Type from an Expanded Access Study of Defibrotide for Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome

Adults Receiving Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Stem Cell Transplantation (HSCT): Final Results from the Expanded-Access Program

Timing of Diagnosis and Severity of Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) at Diagnosis after Hematopoietic Stem Cell Transplantation: Results from a Retrospective Chart Review

Pooled Analysis of Defibrotide Studies in the Treatment of Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Stem Cell Transplantation (HSCT) or Chemotherapy without HSCT

Timing of Defibrotide Initiation in Patients with Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) and Multi-Organ Dysfunction (MOD) after Hematopoietic Stem Cell Transplantation (HSCT): Results from a Retrospective Chart Review

Successful MPB Therapy Followed By Bortezomib Maintenance for Non-Transplant Eligible Patients with Newly Diagnosed Multiple Myeloma: Japanese Phase 2 Study - Broad-J Study

Pooled Analysis of Day +100 Survival for Defibrotide-Treated Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) and Ventilator or Dialysis Dependence Following Hematopoietic Stem Cell Transplantation (HSCT)

Efficacy and Safety of Defibrotide in Pediatric Patients with Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Stem Cell Transplantation (HSCT): Final Results from the Expanded-Access Program

Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Post-Hematopoietic Stem Cell Transplantation (HSCT) in Patients with Neuroblastoma: Final Data from the Defibrotide Expanded-Access Program

Impact on Outcomes of Baseline Bilirubin in Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Receiving Defibrotide Treatment: A Post-Hoc Analysis

Timing of Initiation of Defibrotide Post-Diagnosis of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Post-Hematopoietic Stem Cell Transplantation: Exploratory Age-Group Analysis from an Expanded Access Study

Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Post-Hematopoietic Stem Cell Transplantation (HSCT) in Patients with Acute Leukemias: A Subgroup Analysis from the Defibrotide Expanded-Access Program

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American Society of Hematology

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ASH Publications

American Society of Hematology

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