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Journal Articles

Effects of a Novel Orally Bioavailable Small Molecule (Imidazolyl Ethanamide Pentandioic Acid) on Acute Radiation Syndrome

Dirk Pleimes, MD, Vivienne Bunker, Michael Meyer, Maciej Czajkowski

Blood (2018) 132 (Supplement 1): 5089.

https://doi.org/10.1182/blood-2018-99-114490

Published: 2018

Journal Articles

Prospective, Multi-Center, Phase I Clinical Trial of PLX-R18 Placental Expanded Adherent Stromal Cells in Subjects with Incomplete Hematopoietic Recovery after Hematopoietic Cell Transplantation

Hillard M Lazarus, MD, Leland Metheny, MD, Tsila Zuckerman, MD, Carolina Escobar, MD, Joseph P. McGuirk, DO, Yael Rosen, MD, Jacob M. Rowe, MD

Blood (2018) 132 (Supplement 1): 3379.

https://doi.org/10.1182/blood-2018-99-116239

Published: 2018

Journal Articles

Prostaglandin E2 Promotes Recovery of Thymus in Survivors of the Hematopoietic Acute Radiation Syndrome (H-ARS)

TONG WU, MD PhD, Artur Plett, PhD, Hui Lin Chua, PhD, Louis M. Pelus, PhD, Christie M. Orschell, PhD

Blood (2017) 130 (Supplement 1): 1008.

https://doi.org/10.1182/blood.V130.Suppl_1.1008.1008

Published: 2017

Journal Articles

Thrombopoietin-Receptor Agonist Romiplostim Attenuates Hematopoietic System Injury By Promoting the Recovery of Early Hematopoiesis and the Hematopoietic Environment in the Bone Marrow and Spleen of Mice Exposed to Lethal Total Body γ-Irradiation

Masaru Yamaguchi, PhD, Tokuhisa Hirouchi, Syuta Miura, Kengo Waga, Haruhiko Yoshioka, Jun Watanabe, Ikuo Kashiwakura, PhD

Blood (2017) 130 (Supplement 1): 1153.

https://doi.org/10.1182/blood.V130.Suppl_1.1153.1153

Published: 2017

Journal Articles

Prostaglandin E 2 Prevents Apoptosis and Promotes Homeostasis of Hematopoietic Stem Cells after Lethal Irradiation through Alteration of p53 and TNF Signaling

Andrea M Patterson, PhD, Liqiong Liu, MD PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD

Blood (2017) 130 (Supplement 1): 3766.

https://doi.org/10.1182/blood.V130.Suppl_1.3766.3766

Published: 2017

Journal Articles

Intramuscular Administration of Placenta-Derived Stromal Cells Enhances Survival of Rhesus Macaque Monkeys Exposed to Total Body Irradiation

Noa Sher, PhD, Tal Prezma, Dana Fuchs-Telem, Niva Shraga- Heled, Simon Authier, Polly Chang, Alexis Ascah, James Bakke, Janet Gahagen, Racheli Ofir, PhD

Blood (2017) 130 (Supplement 1): 3784.

https://doi.org/10.1182/blood.V130.Suppl_1.3784.3784

Published: 2017

Journal Articles

Human Placenta-Derived Stromal Cells Rescue Mice from Radiation-Induced Bone Marrow Failure: A Cytof-Based Mechanistic Analysis

Hoshea Allen, PhD, Noa Sher, PhD, Shiran Rekhes, PhD, Lena Pinzur, MSc, Tal Prezma, MSc, Raphael Gorodetsky, PhD, Hans Dieter Volk, PhD, Zami Aberman, Racheli Ofir, PhD

Blood (2016) 128 (22): 2677.

https://doi.org/10.1182/blood.V128.22.2677.2677

Published: 2016

Journal Articles

Prostaglandin E 2 Promotes Early Bone Marrow Reconstitution for Survival after Lethal Irradiation

Andrea M. Patterson, PhD, Pratibha Singh, PhD, Hongge Li, PhD, Hui Lin Chua, PhD, Alexa Fisher, BS, Carol Sampson, MS, Artur Plett, PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD

Blood (2016) 128 (22): 1481.

https://doi.org/10.1182/blood.V128.22.1481.1481

Published: 2016

Journal Articles

Sargramostim Accelerates Leukocyte Recovery and Improves Mortality Rate at Day 60 in a Non-Human Primate Model of Hematopoietic Acute Radiation Syndrome When Administered 48 h after Total Body Irradiation

Nicholas P. Clayton, MSc, Eric J.J. Charpentier, MSc, Emily R. LaCasse, BSc, Richard C. Khan-Malek, MS, Joan M. Keutzer, PhD

Blood (2016) 128 (22): 2512.

https://doi.org/10.1182/blood.V128.22.2512.2512

Published: 2016

Journal Articles

Translational Modeling to Identify Human Dosing of Filgrastim to Improve Overall Survival (OS) in Acute Radiation Syndrome (ARS)

John Harrold, Philippe Jacqmin, Per Olsson, Isabelle Delor, Phuong Khanh Morrow, MD, Bing-Bing Yang, PhD, Andrew Chow, Juan Jose Perez-Ruixo

Blood (2014) 124 (21): 690.

https://doi.org/10.1182/blood.V124.21.690.690

Published: 2014

Journal Articles

Association of Hematological Nadirs and Survival in a Non-Human Primate Model of Hematopoietic Syndrome of Acute Radiation Syndrome

Zoya Gluzman Poltorak, PhD MBA, Vainstein Vladimir, MD MS, Lena A. Basile, PhD JD

Blood (2014) 124 (21): 4354.

https://doi.org/10.1182/blood.V124.21.4354.4354

Published: 2014

Journal Articles

Recovery of Hematopoiesis and Increased Survival Following Radiological Injury through Modulation of Prostaglandin E 2 (PGE 2 ) Signaling.

Jonathan Hoggatt, Ph.D., Artur Plett, Ph.D., Carol Sampson, M.S., Hui Lin Chua, Ph.D., Christie M. Orschell, Ph.D., Louis M. Pelus, PhD

Blood (2010) 116 (21): 2638.

https://doi.org/10.1182/blood.V116.21.2638.2638

Published: 2010

Journal Articles

Cryopreserved Ex-Vivo Expanded Murine Hematopoietic Progenitors Can Engraft Across MHC Barriers and Improve Survival In a Murine Model of Acute Radiation Syndrome.

Filippo Milano, MD, PhD, Ian Nicoud, PhD, Daniel Weber, Shelly Heimfeld, PhD, Irwin D. Bernstein, MD, Colleen Delaney

Blood (2010) 116 (21): 1463.

https://doi.org/10.1182/blood.V116.21.1463.1463

Published: 2010

Journal Articles

A Multi-Lineage Oral Hemokine™ HQK-1002 Enhances Neutrophil Recovery in Sub-Lethally Irradiated Mice and in Baboons.

Susan Perrine, MD, Michael Boosalis, PhD, Stanley Kosanke, DVM, Gary White, DVM, Serguei A. Castaneda, MD, Audry Thomson, MS, Hua Cao, PhD, Ray Fei, MD, Ronald Berenson, MD, Douglas Faller, MD, PhD

Blood (2009) 114 (22): 2509.

https://doi.org/10.1182/blood.V114.22.2509.2509

Published: 2009

Journal Articles

HE2100 (androst-5-ene-3β, 17β-diol), an Adrenal Hormone, Protects Rhesus Macaques from Lethal Total Body Irradiation (TBI)- Induced Severe Neutropenia and Thrombocytopenia.

Dwight R. Stickney, Charles Dowding, Simon Authier, Armando Garsd, Nanette Onizuka-Handa, Chris Reading, James Frincke

Blood (2005) 106 (11): 5223.

https://doi.org/10.1182/blood.V106.11.5223.5223

Published: 2005

NARROW

Effects of a Novel Orally Bioavailable Small Molecule (Imidazolyl Ethanamide Pentandioic Acid) on Acute Radiation Syndrome

Prospective, Multi-Center, Phase I Clinical Trial of PLX-R18 Placental Expanded Adherent Stromal Cells in Subjects with Incomplete Hematopoietic Recovery after Hematopoietic Cell Transplantation

Prostaglandin E2 Promotes Recovery of Thymus in Survivors of the Hematopoietic Acute Radiation Syndrome (H-ARS)

Thrombopoietin-Receptor Agonist Romiplostim Attenuates Hematopoietic System Injury By Promoting the Recovery of Early Hematopoiesis and the Hematopoietic Environment in the Bone Marrow and Spleen of Mice Exposed to Lethal Total Body γ-Irradiation

Prostaglandin E 2 Prevents Apoptosis and Promotes Homeostasis of Hematopoietic Stem Cells after Lethal Irradiation through Alteration of p53 and TNF Signaling

Intramuscular Administration of Placenta-Derived Stromal Cells Enhances Survival of Rhesus Macaque Monkeys Exposed to Total Body Irradiation

Human Placenta-Derived Stromal Cells Rescue Mice from Radiation-Induced Bone Marrow Failure: A Cytof-Based Mechanistic Analysis

Prostaglandin E 2 Promotes Early Bone Marrow Reconstitution for Survival after Lethal Irradiation

Sargramostim Accelerates Leukocyte Recovery and Improves Mortality Rate at Day 60 in a Non-Human Primate Model of Hematopoietic Acute Radiation Syndrome When Administered 48 h after Total Body Irradiation

Translational Modeling to Identify Human Dosing of Filgrastim to Improve Overall Survival (OS) in Acute Radiation Syndrome (ARS)

Association of Hematological Nadirs and Survival in a Non-Human Primate Model of Hematopoietic Syndrome of Acute Radiation Syndrome

Recovery of Hematopoiesis and Increased Survival Following Radiological Injury through Modulation of Prostaglandin E 2 (PGE 2 ) Signaling.

Cryopreserved Ex-Vivo Expanded Murine Hematopoietic Progenitors Can Engraft Across MHC Barriers and Improve Survival In a Murine Model of Acute Radiation Syndrome.

A Multi-Lineage Oral Hemokine™ HQK-1002 Enhances Neutrophil Recovery in Sub-Lethally Irradiated Mice and in Baboons.

HE2100 (androst-5-ene-3β, 17β-diol), an Adrenal Hormone, Protects Rhesus Macaques from Lethal Total Body Irradiation (TBI)- Induced Severe Neutropenia and Thrombocytopenia.

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American Society of Hematology

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American Society of Hematology

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