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Journal Articles

Mitigation of Vascular Permeability Using Bradykinin Receptor Antagonist and Anti-Fibrinolytic Agent in Rats with Polytrauma and Hemorrhagic Shock

Xiaowu Wu, MD MSc, Daniel N. Darlington, PhD, Josue Garciamarcano, Bin Liu, BS, Jeffrey D Keesee, BS, James Bynum, PhD, Andrew P. Cap, MD PhD

Blood (2019) 134 (Supplement_1): 2345.

https://doi.org/10.1182/blood-2019-130278

Published: 2019

Journal Articles

A Phase 1a/1b Trial of ST-001, a Fenretinide Phospholipid Suspension for 4-Hour Intravenous Infusion in Relapsed/Refractory T-Cell Non-Hodgkin's Lymphoma

Ayad Al-Katib, MD, Timothy M. Kuzel, MD, Ralph Parchment, PhD

Blood (2019) 134 (Supplement_1): 4041.

https://doi.org/10.1182/blood-2019-127278

Published: 2019

Journal Articles

Trauma Leads to a Rise in Intracellular cAMP and Adenylate Cyclase Activity in Rats

Daniel N Darlington, PhD, Bunyan Teng, PhD, Xiaowu Wu, MD MSc, Andrew P Cap, MD PhD

Blood (2018) 132 (Supplement 1): 1155.

https://doi.org/10.1182/blood-2018-99-114805

Published: 2018

Journal Articles

A Novel and Potent Inhibitor of E-Selectin, GMI-1687, Attenuates Thrombus Formation and Augments Chemotherapeutic Intervention of AML in Preclinical Models Following Subcutaneous Administration

John Peterson, PhD, Myung-Gi Baek, PhD, Silvia Locatelli-Hoops, PhD, Ji-Won Lee, PhD, Lingquan Deng, PhD, David A Stewart, Theodore AG Smith, PhD, Daniel Durant Myers, DVM, MPH, William E Fogler, PhD, John L Magnani, PhD

Blood (2018) 132 (Supplement 1): 4678.

https://doi.org/10.1182/blood-2018-99-116779

Published: 2018

Journal Articles

Severe Trauma Leads to a Fall in Intracellular Triphosphates and a Rise in cAMP in Platelets

Daniel N Darlington, PhD, Xiaowu Wu, MD MSc, Andrew P. Cap, MD PhD

Blood (2017) 130 (Supplement 1): 2318.

https://doi.org/10.1182/blood.V130.Suppl_1.2318.2318

Published: 2017

Journal Articles

Lethal and Sub-Lethal Irradiation of Sprague-Dawley Rats Causes Development of Dense Red Blood Cells

Janice Zawaski, PhD, Alireza Paikari, MD, Celeste K Kanne, BA, Omaima Sabek, PhD, M Waleed Gaber, PhD, Vivien Sheehan, MD PhD

Blood (2017) 130 (Supplement 1): 4738.

https://doi.org/10.1182/blood.V130.Suppl_1.4738.4738

Published: 2017

Journal Articles

Pegylated Carboxyhemoglobin (SANGUINATE ® ) Restores Blood Flow and Tissue Oxygenation in a Novel Rat Model of Acute Vaso-Occlusive Crisis

Bjorn K. Song, PhD, William H. Nugent, PhD

Blood (2017) 130 (Supplement 1): 3517.

https://doi.org/10.1182/blood.V130.Suppl_1.3517.3517

Published: 2017

Journal Articles

Platelets from Fresh and Cold-Stored Whole Blood Contribute to Clot Formation after Transfusion in Rats with Acute Traumatic Coagulopathy

Xiaowu Wu, MD MMSc, Robbie Montgomery, MS, Bin Liu, BS, Jeffrey D Keesee, BS, Avi Benov, MD, Daniel N Darlington, PhD, Andrew P Cap, MD PhD

Blood (2016) 128 (22): 1457.

https://doi.org/10.1182/blood.V128.22.1457.1457

Published: 2016

Journal Articles

Nonclinical Safety of SHP 826 (BAX 826), a Next Generation Extended Half-Life Recombinant Factor VIII Product

Veronika Ehrlich, Peter Leidenmuehler, Barbara Dietrich, Gerald Hoebarth, Tanja Ruthsatz, Peter L. Turecek, PhD, Martin Wolfsegger, Cstat (RSS), Alfred Weber, Herbert Gritsch, Werner Hoellriegl, Marietta Turecek

Blood (2016) 128 (22): 4977.

https://doi.org/10.1182/blood.V128.22.4977.4977

Published: 2016

Journal Articles

Histological Evaluation of Megakaryocytes and Angiogenic Signaling Molecules of Bone Marrow in Experimentally Induced Iron Deficiency Anemia

Jessica Garcia, MD, Peggy Mankin, BS, MA, Pedro De Alarcon, MD

Blood (2015) 126 (23): 953.

https://doi.org/10.1182/blood.V126.23.953.953

Published: 2015

Journal Articles

Development of an Anti-HTLV-1 Vaccine for the Treatment of Adult T-Cell Leukemia/Lymphoma

Déborah Revaud, PhD, Ana Bejanariu, PhD, Lamya Loussaief, Emeline Sarry, Abdel Zemmar, Guillaume Deplaine, PhD, Téreza Coman, MD, Julien Rossignol, MD, Olivier Hermine, Cecile Bauche, PhD

Blood (2015) 126 (23): 4010.

https://doi.org/10.1182/blood.V126.23.4010.4010

Published: 2015

Journal Articles

Cirmtuzumab (UC-961), a First-in-Class Anti-ROR1 Monoclonal Antibody: Planned Interim Analysis of Initial Phase 1 Cohorts

Michael Y. Choi, MD, George F. Widhopf, II, PhD, Januario Castro, MD, Hongying Li, PhD, Reilly L Kidwell, BS, BA, CCRC, Sam C Zhang, B.A., Tiffany Juarez, PhD, Susette Gorak, Laura Z. Rassenti, PhD, Karen Messer, PhD, Charles Prussak, PhD, Catriona HM Jamieson, MD PhD, Thomas J. Kipps, MD PhD

Blood (2015) 126 (23): 1736.

https://doi.org/10.1182/blood.V126.23.1736.1736

Published: 2015

Journal Articles

Pharmacokinetics of BAX 826, a Polysialylated Full-Length rFVIII, in Hemophilia a Mice, Rats, and Cynomolgus Monkeys

Alexandra Schiviz, DVM, Gerald Hoebarth, Martin Wolfsegger, Paolo Rossato, Alfred Weber, Herbert Gritsch, Hanspeter Rottensteiner, PhD, Peter L. Turecek, PhD, Friedrich Scheiflinger, PhD, Werner Hoellriegl, DVM, Marietta Putz, MS

Blood (2015) 126 (23): 1073.

https://doi.org/10.1182/blood.V126.23.1073.1073

Published: 2015

Journal Articles

The Histone Deacetylase 1 and 2 (HDAC1/2) Inhibitor ACY-957 Increases Epsilon (HbE) and Gamma (HbG) Globin mRNA in the Peripheral Blood of Non-Anemic Rats and Monkeys

Jeffrey R Shearstone, PhD, Apurva Chonkar, MS, Kailash Bhol, PhD, Simon S Jones, PhD, Matt Jarpe, PhD

Blood (2015) 126 (23): 3378.

https://doi.org/10.1182/blood.V126.23.3378.3378

Published: 2015

Journal Articles

Rivaroxaban-Mediated Vascular Relaxation As a Potential Cause of Headaches and Dizziness

Jon Mabley, PhD, Greg Scutt, PhD, Kathryn Jane Lang, MRCP, MBBS, Jignesh P Patel, PhD, Roopen Arya, PhD

Blood (2015) 126 (23): 2334.

https://doi.org/10.1182/blood.V126.23.2334.2334

Published: 2015

Journal Articles

CPX-351 Markedly Reduces Renal and Hepatic Clearance Rates for Cytarabine (Cyt) and Daunorubicin (Daun) in Rats with an Associated Decrease in Excretory and Metabolic Burden Despite Providing Dramatic Increases in Systemic Drug Exposure Compared to Conventional Cyt+Daun

Lawrence D Mayer, PhD, Jeffrey Fulton, Heasook Kim-Kang, Yijun Yi, Peter Wang, Paul Tardi, PhD, Xiaowei Xi, Dennis Heller, PhD

Blood (2014) 124 (21): 2305.

https://doi.org/10.1182/blood.V124.21.2305.2305

Published: 2014

Journal Articles

Drug Interactions of Newer Oral Anticoagulants Dabigatran, Rivaroxaban, and Apixaban with Routinely Used Nonanticoagulant/Antiplatelet Drugs

Shermin Sayani, BS, Omer Iqbal, MD, Debra Hoppensteadt, PhD, Jawed Fareed, PhD

Blood (2014) 124 (21): 4267.

https://doi.org/10.1182/blood.V124.21.4267.4267

Published: 2014

Journal Articles

Modulating the Antithrombin-Mediated in Vivo Clearance of Coagulation Factor VIIa

Henrik Østergaard, PhD, Lene Hansen, Hermann Pelzer, PhD, Henrik Agersø, Anette A. Pedersen, Tina H. Glue, Laust B. Johnsen, PhD, Gorm Andersen, Jais R. Bjelke, Jens Breinholt, Henning Stennicke, MSc, PhD, Prafull S. Gandhi, PhD, Ole H. Olsen, PhD, Mette B. Hermit

Blood (2014) 124 (21): 4233.

https://doi.org/10.1182/blood.V124.21.4233.4233

Published: 2014

Journal Articles

Infusion of Red Blood Cell-Derived Microparticles (RMPs) Reduced Intracerebral Bleeding Following Hemorrhagic Stroke in a Rat Model

Kunjan R Dave, PhD, Sebastian Koch, MD, Vibha Shukla, Isabel Saul, Carlos Bidot, BS, Allen Liu, Miguel Perez-Pinzon, PhD, Wenche Jy, PhD, Yeon-Soong Ahn, MD

Blood (2014) 124 (21): 1556.

https://doi.org/10.1182/blood.V124.21.1556.1556

Published: 2014

Journal Articles

Whole Blood Stored at 4°C for 7 Days Is Equivalent to Fresh Whole Blood for Resuscitation of Severe Polytrauma

Daniel N Darlington, PhD, Jacob Chen, MD, Xiaowu Wu, MD, Jeffery Keesee, BS, Bin Liu, BS, Andrew P Cap, MDPhD

Blood (2014) 124 (21): 1558.

https://doi.org/10.1182/blood.V124.21.1558.1558

Published: 2014

NARROW

Mitigation of Vascular Permeability Using Bradykinin Receptor Antagonist and Anti-Fibrinolytic Agent in Rats with Polytrauma and Hemorrhagic Shock

A Phase 1a/1b Trial of ST-001, a Fenretinide Phospholipid Suspension for 4-Hour Intravenous Infusion in Relapsed/Refractory T-Cell Non-Hodgkin's Lymphoma

Trauma Leads to a Rise in Intracellular cAMP and Adenylate Cyclase Activity in Rats

A Novel and Potent Inhibitor of E-Selectin, GMI-1687, Attenuates Thrombus Formation and Augments Chemotherapeutic Intervention of AML in Preclinical Models Following Subcutaneous Administration

Severe Trauma Leads to a Fall in Intracellular Triphosphates and a Rise in cAMP in Platelets

Lethal and Sub-Lethal Irradiation of Sprague-Dawley Rats Causes Development of Dense Red Blood Cells

Pegylated Carboxyhemoglobin (SANGUINATE ® ) Restores Blood Flow and Tissue Oxygenation in a Novel Rat Model of Acute Vaso-Occlusive Crisis

Platelets from Fresh and Cold-Stored Whole Blood Contribute to Clot Formation after Transfusion in Rats with Acute Traumatic Coagulopathy

Nonclinical Safety of SHP 826 (BAX 826), a Next Generation Extended Half-Life Recombinant Factor VIII Product

Histological Evaluation of Megakaryocytes and Angiogenic Signaling Molecules of Bone Marrow in Experimentally Induced Iron Deficiency Anemia

Development of an Anti-HTLV-1 Vaccine for the Treatment of Adult T-Cell Leukemia/Lymphoma

Cirmtuzumab (UC-961), a First-in-Class Anti-ROR1 Monoclonal Antibody: Planned Interim Analysis of Initial Phase 1 Cohorts

Pharmacokinetics of BAX 826, a Polysialylated Full-Length rFVIII, in Hemophilia a Mice, Rats, and Cynomolgus Monkeys

The Histone Deacetylase 1 and 2 (HDAC1/2) Inhibitor ACY-957 Increases Epsilon (HbE) and Gamma (HbG) Globin mRNA in the Peripheral Blood of Non-Anemic Rats and Monkeys

Rivaroxaban-Mediated Vascular Relaxation As a Potential Cause of Headaches and Dizziness

CPX-351 Markedly Reduces Renal and Hepatic Clearance Rates for Cytarabine (Cyt) and Daunorubicin (Daun) in Rats with an Associated Decrease in Excretory and Metabolic Burden Despite Providing Dramatic Increases in Systemic Drug Exposure Compared to Conventional Cyt+Daun

Drug Interactions of Newer Oral Anticoagulants Dabigatran, Rivaroxaban, and Apixaban with Routinely Used Nonanticoagulant/Antiplatelet Drugs

Modulating the Antithrombin-Mediated in Vivo Clearance of Coagulation Factor VIIa

Infusion of Red Blood Cell-Derived Microparticles (RMPs) Reduced Intracerebral Bleeding Following Hemorrhagic Stroke in a Rat Model

Whole Blood Stored at 4°C for 7 Days Is Equivalent to Fresh Whole Blood for Resuscitation of Severe Polytrauma

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American Society of Hematology

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American Society of Hematology

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