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Journal Articles

Fetal Hemoglobin Measurement per Red Blood Cell Provides Biological and Clinical Protective Thresholds

Nicolas Hebert, Rakotoson Marie Georgine, PhD, Gwellaouen Bodivit, Etienne Audureau, MD PhD, Nadia Oubaya, Sadaf Pakdaman, Mehdi Sakka, Gaetana Di Liberto, PhD, Philippe Chadebech, PhD, Benoît Vingert, PhD, France Pirenne, MD PhD, Frédéric Galactéros, MD PhD, Marie Cambot, PhD, Pablo Bartolucci, MD PhD

Blood (2019) 134 (Supplement_1): 1008.

https://doi.org/10.1182/blood-2019-126727

Published: 2019

Journal Articles

Targeting Transferrin Receptor 2: A Novel "Erythropoiesis-Stimulating Approach" in a Model of Anemia of Chronic Kidney Disease

Violante Olivari, MSc, Maria Rosa Lidonnici, PhD, Mariateresa Pettinato, Laura Silvestri, PhD, Giuliana Ferrari, PhD, Clara Camaschella, MD, Antonella Nai, PhD

Blood (2019) 134 (Supplement_1): 956.

https://doi.org/10.1182/blood-2019-125783

Published: 2019

Journal Articles

Pharmacokinetics-Guided Dosing of Hydroxyurea Can Achieve Near-Pancellular Fetal Hemoglobin Expression in Sickle Cell Anemia: F-Cell Analysis As a Benchmark for Disease-Modifying Therapy

Charles T. Quinn, MD, Omar Niss, MD, Amanda Pfeiffer, Jennifer Korpik, Holly Bonar, Mary Reynaud, Russell E. Ware, MD PhD, Patrick T. McGann, MD

Blood (2019) 134 (Supplement_1): 892.

https://doi.org/10.1182/blood-2019-130414

Published: 2019

Journal Articles

Aberrant Responsiveness of Erythropoiesis to Iron Deficiency in Polycythemia Vera

Maria Feola, PhD, Daniel Moskop, Nada Terra, Young C. Park, Andrew Dunbar, MD, Ross L. Levine, MD, Ronald Hoffman, MD, Yelena Ginzburg, MD

Blood (2019) 134 (Supplement_1): 429.

https://doi.org/10.1182/blood-2019-131095

Published: 2019

Journal Articles

Mcph1 , Mutated in Primary Microcephaly, Is Required to Complete Terminal Erythroid Differentiation

Yoann Vial, PharmD, Jeannette Nardelli, PhD, Justine Rousselot, Emilie Lepeu, Michele Souyri, PhD, Sandrine Passemard, MD PhD, Helene Cave, PharmD, PhD, Severine Drunat, PharmD, PhD

Blood (2019) 134 (Supplement_1): 1192.

https://doi.org/10.1182/blood-2019-126475

Published: 2019

Journal Articles

Hepcidin-Mediated Ferroportin Control in the Bone Marrow Is Dispensable

Katja Muedder, Bonadonna Michael, Bruno Galy, PhD, Martina U. Muckenthaler, PhD, Sandro Altamura, PhD

Blood (2019) 134 (Supplement_1): 3531.

https://doi.org/10.1182/blood-2019-126655

Published: 2019

Journal Articles

Similar Hemostatic Responses to Hypovolemia in Hemorrhage and Lbnp Reveals a Hyperfibrinolytic Subset of Baboons

Maryanne Herzig, PhD, Morten Zaar, PhD, Chriselda Fedyk, Bijaya Kumar Parida, PhD, Carmen Hinojosa-Laborde, PhD, Robert E Shade, PhD, Heather F. Pidcoke, MD PhD, Victor A Convertion, PhD, Andrew P. Cap, MD PhD

Blood (2019) 134 (Supplement_1): 3633.

https://doi.org/10.1182/blood-2019-131792

Published: 2019

Journal Articles

Safe Use of Hydroxyurea in Sickle Cell Disease Patients Hospitalized for Painful Vaso-Occlusive Episodes: Results of the Randomized, Open-Label Helps Study

Nicola Conran, PhD, Kleber Yotsumoto Fertrin, MD PhD, Claudia de Alvarenga Maximo, MD, Thais Oliveira, B.Sc., Clarisse Lobo, MD PhD, Fernando Ferreira Costa, MD PhD

Blood (2019) 134 (Supplement_1): 2303.

https://doi.org/10.1182/blood-2019-130106

Published: 2019

Journal Articles

Additive Effects of Decreased TfR1 and Ablated Erfe Improve Both Ineffective Erythropoiesis and Iron Overload in β-Thalassemic Mice

Marc Ruiz Martinez, PhD, Wenbin An, MD, Maria Feola, PhD, Tomas Ganz, MD PhD, Yelena Ginzburg, MD

Blood (2018) 132 (Supplement 1): 847.

https://doi.org/10.1182/blood-2018-99-119426

Published: 2018

Journal Articles

Hemoglobin S Induces Exposure of Red Blood Cell Membrane Skeleton Microdomains Bearing Mannose That Stimulate Phagocytosis By Macrophages: A Molecular Basis for Hemolysis in Sickle Cell Disease but Protection Against Plasmodium Falciparum malaria

Blood (2018) 132 (Supplement 1): 3642.

https://doi.org/10.1182/blood-2018-99-117290

Published: 2018

Journal Articles

Acute Hemolysis Induces Pro-Angiogenic Molecule Production and Neovascularization In Vivo

Erica M.F. Gotardo, PhD, Hanan Chweih, M.Sc., Pamela L. Brito, B.Sc, Flavia C. Leonardo, PhD, Raquel Costa, PhD, Raquel Soares, PhD, Fernando F. Costa, MD, PhD, Nicola Conran, PhD

Blood (2018) 132 (Supplement 1): 3608.

https://doi.org/10.1182/blood-2018-99-118416

Published: 2018

Journal Articles

Exploring the Mechanisms of Thalassemic Erythropoiesis Improvement Caused By Bone Marrow Tfr2 Deletion

Antonella Nai, PhD, Irene Artuso, MSc, Maria Rosa Lidonnici, PhD, Sandro Altamura, PhD, Giacomo Mandelli, PhD, Mariateresa Pettinato, MSc, Martina U. Muckenthaler, PhD, Laura Silvestri, PhD, Giuliana Ferrari, PhD, Clara Camaschella, MD

Blood (2018) 132 (Supplement 1): 3624.

https://doi.org/10.1182/blood-2018-99-115835

Published: 2018

Journal Articles

Phase 2 Clinical Trial Results for Bitopertin, an Oral Glycine Transporter 1 Inhibitor, in Patients with Non-Transfusion Dependent Beta-Thalassemia

Ali Taher, MD PhD, Vip Viprakasit, MD DPhil, Maria Domenica Cappellini, MD, Dominik Kraus, PhD, Patrick Cech, PhD, Volz Dietmar, PhD, Erica Winter, PharmD, Norman Alan Mazer, MD PhD, Stephane Nave, MD, Juergen Dukart, PhD, Franziska Schaedeli Stark, PhD, Annette Koerner, PhD, Omar Khwaja, MD PhD, Ricardo Hermosilla, DVM, PhD

Blood (2018) 132 (Supplement 1): 3635.

https://doi.org/10.1182/blood-2018-99-114776

Published: 2018

Journal Articles

The Optimal Cut-Off Level for Hemoglobin A2 to Differentiate between Sickle Cell Disease Genotypes

Fayiz Al Shueili, MD, Murtadha K. Al-Khabori, BSc,MD FRCPC, MSc, Salam Al-Kindi, Yasser Wali, MD, Shoaib Al-Zadjali, PhD

Blood (2018) 132 (Supplement 1): 2391.

https://doi.org/10.1182/blood-2018-99-118697

Published: 2018

Journal Articles

FcmR Shapes BCR Signaling in IgM-Positive Leukemia

Alexandra da Palma Guerreiro, PhD, Cornelia Dorweiler, Ismini Halmer, Olaf Merkel, Elena Maria Hartmann, MD, Valeska Berg, PhD, Nina Reinart, Günter Fingerle-Rowson, MD PhD, Gero Knittel, MSc, Christian Pallasch, MD, Andreas Rosenwald, Christian Reinhardt, MD, Clemens-Martin Wendtner, Michael Hallek, MD, Lukas P. Frenzel, MD

Blood (2018) 132 (Supplement 1): 2620.

https://doi.org/10.1182/blood-2018-99-118352

Published: 2018

Journal Articles

Validation of Sickle Cell Disease Severity Score in a Cohort of Hemoglobin SC Disease Patients

Rebecca Marie Rosart, MD, Olivia A. Pestrin, George A. Tomlinson, PhD BSc, MSc, Richard Ward, MBBS, MRCP, Jacob Pendergrast, MD FRCPC, Andrew Binding, MD MSc, FRCPC, Kevin H. M. Kuo, MD MSc, FRCPC

Blood (2018) 132 (Supplement 1): 2287.

https://doi.org/10.1182/blood-2018-99-111364

Published: 2018

Journal Articles

Iron Chelation Improves Erythropoiesis in a Mouse Model of Myelodysplastic Syndrome

Wenbin An, MD, Maria Feola, PhD, Marc Ruiz Martinez, PhD, Amit Verma, MD, Yelena Ginzburg, MD

Blood (2018) 132 (Supplement 1): 2335.

https://doi.org/10.1182/blood-2018-99-119586

Published: 2018

Journal Articles

Quantitative Modeling of Ineffective Hematopoiesis in Myelodysplastic Syndrome Patients Yields Distinct Clinical Phenotypes and Can Identify a State of Disease Predictive of Loss of Response to Azacitidine

Roman M Shapiro, MD, Alejandro Lazo-Langner, MD MSc, Adam R Stinchcombe, PhD

Blood (2018) 132 (Supplement 1): 3104.

https://doi.org/10.1182/blood-2018-99-115611

Published: 2018

Journal Articles

Effect of Ropeginterferon Alfa-2b in Prefibrotic Primary Myelofibrosis

Heinz Gisslinger, Bettina Gisslinger, Martin Schalling, MSc, Kurt Krejcy, PhD, Rudolf S. Widmann, PhD BSc, Robert Kralovics, PhD, Maria-Theresa Krauth, MD

Blood (2018) 132 (Supplement 1): 3029.

https://doi.org/10.1182/blood-2018-99-119268

Published: 2018

Journal Articles

Mean Corpuscular Volume (MCV) and Mean Corpuscular Hemoglobin (MCH) Determinations in Newborns with Beta Thalassemia

Kaitlin Bierman, Harold M. Maurer, MD, James Harper, MD

Blood (2018) 132 (Supplement 1): 4904.

https://doi.org/10.1182/blood-2018-99-110991

Published: 2018

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Fetal Hemoglobin Measurement per Red Blood Cell Provides Biological and Clinical Protective Thresholds

Targeting Transferrin Receptor 2: A Novel "Erythropoiesis-Stimulating Approach" in a Model of Anemia of Chronic Kidney Disease

Pharmacokinetics-Guided Dosing of Hydroxyurea Can Achieve Near-Pancellular Fetal Hemoglobin Expression in Sickle Cell Anemia: F-Cell Analysis As a Benchmark for Disease-Modifying Therapy

Aberrant Responsiveness of Erythropoiesis to Iron Deficiency in Polycythemia Vera

Mcph1 , Mutated in Primary Microcephaly, Is Required to Complete Terminal Erythroid Differentiation

Hepcidin-Mediated Ferroportin Control in the Bone Marrow Is Dispensable

Similar Hemostatic Responses to Hypovolemia in Hemorrhage and Lbnp Reveals a Hyperfibrinolytic Subset of Baboons

Safe Use of Hydroxyurea in Sickle Cell Disease Patients Hospitalized for Painful Vaso-Occlusive Episodes: Results of the Randomized, Open-Label Helps Study

Additive Effects of Decreased TfR1 and Ablated Erfe Improve Both Ineffective Erythropoiesis and Iron Overload in β-Thalassemic Mice

Hemoglobin S Induces Exposure of Red Blood Cell Membrane Skeleton Microdomains Bearing Mannose That Stimulate Phagocytosis By Macrophages: A Molecular Basis for Hemolysis in Sickle Cell Disease but Protection Against Plasmodium Falciparum malaria

Acute Hemolysis Induces Pro-Angiogenic Molecule Production and Neovascularization In Vivo

Exploring the Mechanisms of Thalassemic Erythropoiesis Improvement Caused By Bone Marrow Tfr2 Deletion

Phase 2 Clinical Trial Results for Bitopertin, an Oral Glycine Transporter 1 Inhibitor, in Patients with Non-Transfusion Dependent Beta-Thalassemia

The Optimal Cut-Off Level for Hemoglobin A2 to Differentiate between Sickle Cell Disease Genotypes

FcmR Shapes BCR Signaling in IgM-Positive Leukemia

Validation of Sickle Cell Disease Severity Score in a Cohort of Hemoglobin SC Disease Patients

Iron Chelation Improves Erythropoiesis in a Mouse Model of Myelodysplastic Syndrome

Quantitative Modeling of Ineffective Hematopoiesis in Myelodysplastic Syndrome Patients Yields Distinct Clinical Phenotypes and Can Identify a State of Disease Predictive of Loss of Response to Azacitidine

Effect of Ropeginterferon Alfa-2b in Prefibrotic Primary Myelofibrosis

Mean Corpuscular Volume (MCV) and Mean Corpuscular Hemoglobin (MCH) Determinations in Newborns with Beta Thalassemia

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