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Journal Articles

The Splicing Modulator GEX1A Exhibits Potent Anti-Leukemic Activity Both in Vitro and In Vivo through Inducing an MCL1 Splice-Switch in Pre-Clinical Models of Acute Myeloid Leukemia

Mark Sellin, Ryan Mack, Matthew C. Rhodes, Lei Zhang, PhD, Wei Wei, Peter Breslin, PhD, Stephanie Berg, DO, Suming Huang, PhD, Richard Taylor, PhD, Jiwang Zhang, MD

Blood (2019) 134 (Supplement_1): 2666.

https://doi.org/10.1182/blood-2019-132030

Published: 2019

Journal Articles

Critical Requirement of U2AF1 in the Maintenance and Function of Hematopoietic Stem Cells

Avik Dutta, PhD, Yue Yang, PhD, Bao Le, Golam Mohi, PhD

Blood (2019) 134 (Supplement_1): 1195.

https://doi.org/10.1182/blood-2019-132007

Published: 2019

Journal Articles

SF3B1 Interactions with Chromatin Are Dynamic and Regulated in a Cell Cycle-Dependent Manner

Tushar Murthy, MS, Theresa Bluemn, Manoj M. Pillai, MD, Alex C Minella, MD

Blood (2016) 128 (22): 1480.

https://doi.org/10.1182/blood.V128.22.1480.1480

Published: 2016

Journal Articles

Comprehensive Analysis of Aberrant RNA Splicing in Myelodysplastic Syndromes

Yusuke Shiozawa, MD, Sato Sato-Otsubo, Anna Gallì, Kenichi Yoshida, MD PhD, Tetsuichi Yoshizato, MD, Yusuke Sato, MD, Keisuke Kataoka, MD PhD, Masashi Sanada, MD PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, PhD, Satoru Miyano, PhD, Luca Malcovati, MD, Mario Cazzola, MD, Seishi Ogawa, MD PhD

Blood (2014) 124 (21): 826.

https://doi.org/10.1182/blood.V124.21.826.826

Published: 2014

Journal Articles

Inhibition of Splicing Factor SF3B1: Evaluating Effects on Iron Metabolism in K562 and CD34+ Cells

Simon Knight, PhD, Robert K. Bressin, Upamanyu Basu, Kazunori Koide, PhD, Andrew Dancis, MD

Blood (2014) 124 (21): 1348.

https://doi.org/10.1182/blood.V124.21.1348.1348

Published: 2014

Journal Articles

Allele-Specific Effects Of U2AF1 Mutations On Alternative Splicing

Theresa Okeyo-Owuor, Brian S. White, PhD, Dipika Mohan, Malachi Griffith, PhD, Matthew J. Walter, MD, Timothy Graubert, MD

Blood (2013) 122 (21): 2748.

https://doi.org/10.1182/blood.V122.21.2748.2748

Published: 2013

Journal Articles

Spliceosomal Gene LUC7L2 Mutation Causes Missplicing and Alteration Of Gene Expression In Myeloid Neoplasms

Naoko Hosono, MD, PhD, Hideki Makishima, MD, PhD, Bartlomiej Przychodzen, Ph.D., Jarnail Singh, PhD, Richard A Padgett, PhD, Mikkael A. Sekeres, MD, MS, Andres Jerez, MD, Kenichi Yoshida, MD, Yuichi Shiraishi, PhD, Satoru Miyano, PhD, Masashi Sanada, MD, PhD, Seishi Ogawa, MD, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP

Blood (2013) 122 (21): 470.

https://doi.org/10.1182/blood.V122.21.470.470

Published: 2013

Journal Articles

SF3B1 Mutation Alters The Selection Of 3' RNA Splice Sites In Chronic Lymphocytic Leukemia

Youzhong Wan, Ph. D., Angela N Brooks, Ph. D., Lili Wang, M.D., Ph.D., Carrie Sougnez, Wandi Zhang, Jessica Wong, Dan-Avi Landau, M.D., Dylan Kotliar, BA, David Deluca, Ph. D., Jennifer R. Brown, M.D., Robin Reed, Ph. D., Gad Getz, Ph.D., Matthew Meyerson, MD, PhD, Catherine J Wu, MD

Blood (2013) 122 (21): 117.

https://doi.org/10.1182/blood.V122.21.117.117

Published: 2013

Journal Articles

Role Of Sf3b1 On Hematopoiesis

Manabu Matsunawa, MD, Ryo Yamamoto, MD, PhD, Masashi Sanada, MD, Aiko Sato, PhD, Yusuke Shiozawa, MD, Kenichi Yoshida, MD, Yasunobu Nagata, MD, Ayana Kon, MD, Tetsuichi Yoshizato, MD, Makoto Otsu, MD, PhD, Kyoichi Isono, Haruhiko Koseki, MD, PhD, Hiromitsu Nakauchi, MD, PhD, Seishi Ogawa, MD, PhD

Blood (2013) 122 (21): 600.

https://doi.org/10.1182/blood.V122.21.600.600

Published: 2013

Journal Articles

Whole Exome Sequencing Reveals Acquired SF3B1 Mutations Defining Patients with Acquired Idiopathic Sideroblastic Anaemia

Alexander E Smith, PhD, Syed A Mian, Austin G Kulasekararaj, Azim M Mohamedali, PhD, Ghulam J. Mufti, MD

Blood (2011) 118 (21): 2793.

https://doi.org/10.1182/blood.V118.21.2793.2793

Published: 2011

Journal Articles

Acquired Molecular Defects in Spliceosome Machinery: Novel Pathogenetic Pathways in Myeloid Leukemogenesis

Hideki Makishima, MD, PhD, Hirotoshi Sakaguchi, MD, Valeria Visconte, PhD, Andres Jerez, MD, Anna M Jankowska, PhD, Kathryn M Guinta, Hideki Muramatsu, MD, PhD, Mikkael A Sekeres, MD, Seiji Kojima, MD, PhD, Ramon V. Tiu, MD, Jaroslaw P. Maciejewski, MD, PhD

Blood (2011) 118 (21): 271.

https://doi.org/10.1182/blood.V118.21.271.271

Published: 2011

Journal Articles

Association of SF3B1 with Ring Sideroblasts in patients, In Vivo, and In Vitro models of Spliceosomal Dysfunction

Blood (2011) 118 (21): 457.

https://doi.org/10.1182/blood.V118.21.457.457

Published: 2011

NARROW

The Splicing Modulator GEX1A Exhibits Potent Anti-Leukemic Activity Both in Vitro and In Vivo through Inducing an MCL1 Splice-Switch in Pre-Clinical Models of Acute Myeloid Leukemia

Critical Requirement of U2AF1 in the Maintenance and Function of Hematopoietic Stem Cells

SF3B1 Interactions with Chromatin Are Dynamic and Regulated in a Cell Cycle-Dependent Manner

Comprehensive Analysis of Aberrant RNA Splicing in Myelodysplastic Syndromes

Inhibition of Splicing Factor SF3B1: Evaluating Effects on Iron Metabolism in K562 and CD34+ Cells

Allele-Specific Effects Of U2AF1 Mutations On Alternative Splicing

Spliceosomal Gene LUC7L2 Mutation Causes Missplicing and Alteration Of Gene Expression In Myeloid Neoplasms

SF3B1 Mutation Alters The Selection Of 3' RNA Splice Sites In Chronic Lymphocytic Leukemia

Role Of Sf3b1 On Hematopoiesis

Whole Exome Sequencing Reveals Acquired SF3B1 Mutations Defining Patients with Acquired Idiopathic Sideroblastic Anaemia

Acquired Molecular Defects in Spliceosome Machinery: Novel Pathogenetic Pathways in Myeloid Leukemogenesis

Association of SF3B1 with Ring Sideroblasts in patients, In Vivo, and In Vitro models of Spliceosomal Dysfunction

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American Society of Hematology

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ASH Publications

American Society of Hematology

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