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Journal Articles

A Novel Protease-Mediated Chimeric Antigen Receptor (CAR): "Double-Arm" CAR-T Cell System Improves Target Specificity of CAR-T Cell Therapy

Satoru Aoyama, MD, Shunichiro Yasuda, MD, Daisuke Watanabe, MD, Hiroki Akiyama, MD, PhD, Yoshihiro Umezawa, MD, PhD, Ayako Nogami, MD PhD BPharm, Osamu Miura, MD, PhD, Norihiko Kawamata, MD, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1941.
https://doi.org/10.1182/blood-2019-121973
Published: 2019
Journal Articles

Genomic and Pathway Connectivity Analyses Identify Novel Strategies to Overcome mTOR Inhibitor Resistance In DLBCL

Adam M. Petrich, MD, Violetta V. Leshchenko, PhD, Pei-Yu Kuo, MS, B. Hilda Ye, PhD, Joseph A Sparano, MD, Samir Parekh, MD
Journal: Blood
Blood (2010) 116 (21): 436.
https://doi.org/10.1182/blood.V116.21.436.436
Published: 2010
Journal Articles

The HIV Protease Inhibitor Nelfinavir: A Unique Oral Drug That Inhibits the Proteasome and AKT-Phosphorylation, Induces ER Stress and Sensitizes Bortezomib-Refractory Primary Myeloma Cells and Primary AML Cells towards Bortezomib

Christoph Driessen, MD, Jürgen Bader, Marianne Kraus
Journal: Blood
Blood (2010) 116 (21): 4069.
https://doi.org/10.1182/blood.V116.21.4069.4069
Published: 2010
Journal Articles

Inhibition of Autophagy Promotes Bortezomib-Mediated Cell Death in Myeloma Cells

Terry H. Landowski, PhD, Aluvia M Escalante, Andrew Jefferson, Robert T Dorr, Ronald Lynch
Journal: Blood
Blood (2008) 112 (11): 3677.
https://doi.org/10.1182/blood.V112.11.3677.3677
Published: 2008
Journal Articles

Saquinavir Inhibits Proliferation and Promotes Apoptosis in Imatinib-Resistant Chronic Myelogenous Leukemia Lines and Inhibits CFU-GM Growth in CML Blastic Crisis.

Fabio S. Timeus, MD, PhD, Nicoletta Crescenzio, BSc, Alessandra Doria, BSc, Luiselda C. Foglia, BSc, Daniele Bertin, MD, Giuseppe Saglio, MD, Pier Angelo Tovo, MD
Journal: Blood
Blood (2005) 106 (11): 4846.
https://doi.org/10.1182/blood.V106.11.4846.4846
Published: 2005
Journal Articles

Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss

Barbara N. Phenix, Julian J. Lum, Zelin Nie, Jaime Sanchez-Dardon, Andrew D. Badley
Journal: Blood
Blood (2001) 98 (4): 1078–1085.
https://doi.org/10.1182/blood.V98.4.1078
Published: 2001
Journal Articles

HIV-1 protease inhibitors decrease proliferation and induce differentiation of human myelocytic leukemia cells

Takayuki Ikezoe, Eric S. Daar, Jun-ichi Hisatake, Hirokuni Taguchi, H. Phillip Koeffler
Journal: Blood
Blood (2000) 96 (10): 3553–3559.
https://doi.org/10.1182/blood.V96.10.3553
Published: 2000
Journal Articles

HIV protease inhibitors restore impaired T-cell proliferative response in vivo and in vitro: a viral-suppression–independent mechanism

Clinical Trials & Observations
Wei Lu, Jean-Marie Andrieu
Journal: Blood
Blood (2000) 96 (1): 250–258.
https://doi.org/10.1182/blood.V96.1.250
Published: 2000