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Journal Articles

A Randomized Phase 3 Trial of Blinatumomab Vs. Chemotherapy As Post-Reinduction Therapy in High and Intermediate Risk (HR/IR) First Relapse of B-Acute Lymphoblastic Leukemia (B-ALL) in Children and Adolescents/Young Adults (AYAs) Demonstrates Superior Efficacy and Tolerability of Blinatumomab: A Report from Children's Oncology Group Study AALL1331

Patrick A. Brown, MD, Lingyun Ji, PhD, Xinxin Xu, MS, Meenakshi Devidas, PhD, Laura Hogan, MD, Michael J. Borowitz, MD PhD, Elizabeth A. Raetz, MD, Gerhard Zugmaier, Elad Sharon, MD MPH, Lia Gore, MD, James A. Whitlock, MD, Michael A. Pulsipher, MD, Stephen P. Hunger, MD, Mignon L. Loh, MD
Journal: Blood
Blood (2019) 134 (Supplement_2): LBA-1.
https://doi.org/10.1182/blood-2019-132435
Published: 2019
Journal Articles

Heterozygous Mutations of Clpb As a Newly Identified and Frequent Cause of Severe Congenital Neutropenia

Julia T Warren, MD PhD, Peeradol Wattanasirakul, David H Spencer, MD, Adam Locke, PhD, Vahagn Makaryan, MD, Audrey Anna Bolyard, RN, BS, Karl Welte, Julia Skokowa, MD PhD, David C. Dale, MD, Daniel C. Link, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 433.
https://doi.org/10.1182/blood-2019-129635
Published: 2019
Journal Articles

Timing the Initiation of Multiple Myeloma

Francesco Maura, MD, Even H Rustad, MD, Niccolò Bolli, MD PhD, Venkata Yellapantula, PhD, Daniel A. Leongamornlert, PhD, Ferran Nadeu, BSc, MSc, Nicos Angelopoulos, PhD, Kevin J Dawson, Thomas J Mitchell, Rob Osborne, Bachisio Ziccheddu, PhD, Cristiana Carniti, PhD, Vittorio Montefusco, Paolo Corradini, Kenneth C. Anderson, MD, Philippe Moreau, MD, Elli Papaemmanuil, PhD, Ludmil Alexandrov, Xose S Puente, Elias Campo, Reiner Siebert, PhD, Herve Avet-Loiseau, MD PhD, Nikhil C. Munshi, MD, Peter J Campbell, Ola Landgren, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 573.
https://doi.org/10.1182/blood-2019-124357
Published: 2019
Journal Articles

Late Effects and Subsequent Neoplasms in Survivors of Adolescent and Young Adult Acute Lymphoblastic Leukemia: A Population-Based Analysis Including Impact of Front-Line Regimen Type

Lori S Muffly, MD, Fran Maguire, PhD MPH, Qian Li, MS, Vanessa Kennedy, MD, Theresa H.M. Keegan, PhD MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 421.
https://doi.org/10.1182/blood-2019-124992
Published: 2019
Journal Articles

Long-Term Follow-up of a Phase 1, First-in-Human Open-Label Study of LCAR-B38M, a Structurally Differentiated Chimeric Antigen Receptor T (CAR-T) Cell Therapy Targeting B-Cell Maturation Antigen (BCMA), in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM)

Bai-Yan Wang, MD PhD, Wan-Hong Zhao, MD PhD, Jie Liu, MD, Yin-Xia Chen, MD, Xing-Mei Cao, MD, Yun Yang, MD, Yi-Lin Zhang, MD, Fang-Xia Wang, MD PhD, Peng-Yu Zhang, MD PhD, Bo Lei, MD, Liu-Fang Gu, MD PhD, Jian-Li Wang, MD PhD, Jia-Jia Zhang, MD, Ru Zhang, MD, Hui Zhang, MD, Ying Shen, MD, Ju Bai, PhD, Yan Xu, MD, Xu-Geng Wang, MD PhD, Rui-Li Zhang, MD, Li-Li Wei, MD, Zong-Fang Li, MD PhD, Gai-Xia He, PhD, Yan Geng, MD PhD, Qian He, MD PhD, Qiu-Chuan Zhuang, Msc, Frank Xiao-Hu Fan, MD PhD, Wang-Gang Zhang, MD PhD, Ai-Li He, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 579.
https://doi.org/10.1182/blood-2019-124953
Published: 2019
Journal Articles

Donor-Derived CD19 CAR Cytokine Induced Killer (CIK) Cells Engineered with Sleeping Beauty Transposon for Relapsed B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Chiara F Magnani, PhD, Giuseppe Gaipa, PhD, Daniela Belotti, Giada Matera, Sarah Tettamanti, PhD, Benedetta Cabiati, Chiara Buracchi, PhD, Grazia Fazio, Silvia Zaninelli, Silvia Rigamonti, Stefania Cesana, Valentina Colombo, Giovanni Cazzaniga, PhD, Attilio Rovelli, MD, Adriana Balduzzi, MD, Sara Napolitano, MD, Fabrizio Benedicenti, Eugenio Montini, PhD, Gian Maria Borleri, Silvia Ferrari, MD, Giuseppe Gritti, MD PhD, Federico Lussana, MD, Martino Introna, MD, Alessandro Rambaldi, MD, Giuseppe Dastoli, MD, Andrea Biondi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 200.
https://doi.org/10.1182/blood-2019-125894
Published: 2019
Journal Articles

Affect of Age on Survival and Complications after Hematopoietic Stem Cell Transplantation in Children with β-Thalassemia Major

Yiqi Xu, MD, Yongsheng Ruan, MD, Yuelin He, MD, Jianyun Wen, Xiaoqin Feng, Xuan Liu, Haixia Guo, MD PhD, Chunfu Li, MD, Qareen Haque, Xuedong Wu, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4591.
https://doi.org/10.1182/blood-2019-126596
Published: 2019
Journal Articles

Caplacizumab As Step-up Therapy in Refractory TTP Utilizing Adamts-13 Activity and Evidence of End-Organ Damage

Neel Belani, MD, Adriel Barrios-Anderson, Sc.B, A.B., William Rafelson, MDMBA, Matthew I. Quesenberry, MD, Rabin Niroula, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 4909.
https://doi.org/10.1182/blood-2019-123206
Published: 2019
Journal Articles

Central Nervous System Involvement in Peripheral T-Cell Lymphoma

Sangeetha Gandhi, MBBS, N. Nora Bennani, MD, Sonia Fortin, Thomas M. Habermann, MD, Patrick Johnston, MD, James R. Cerhan, MD PhD, Kay M. Ristow, BS, Carrie A. Thompson, MD, Grzegorz Nowakowski, MD, Yi Lin, MD PhD, Jose C Villasboas, MD, Luis Porrata, MD, Thomas E. Witzig, MD, Ivana Micallef, MD, David J Inwards, MD, Stephen M Ansell, MD PhD, Jonas Paludo, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5293.
https://doi.org/10.1182/blood-2019-131965
Published: 2019
Journal Articles

Adverse Events during Induction Therapy in Pediatric Acute Lymphoblastic Lymphoma (ALL)

Zachary West, BS, Kristen Allen, MPH, Caitlin Monroe, MPH, Sharon M. Castellino, MD MSc, Tamara P. Miller, MDMSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 5809.
https://doi.org/10.1182/blood-2019-131873
Published: 2019
Journal Articles

Neurodevelopmental Disorders in Pediatric Sickle Cell Disease

Eboni I. Lance, MD, Alicia D. Cannon, PhD, Bruce K. Shapiro, MD, Michael V. Johnston, MD, James F. Casella, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1016.
https://doi.org/10.1182/blood-2019-121968
Published: 2019
Journal Articles

CD19-Targeting CAR-T Cell Therapy in CNS Lymphoma

Tanya Siddiqi, MD, Xiuli Wang, PhD, Joycelynne Palmer, PhD, Leslie L. Popplewell, MD FRCPA, Liana Nikolaenko, MD, Alex F. Herrera, MD, Lihua E Budde, MD PhD, Laura Lim, Vibhuti Vyas, MS, Christine E Brown, PhD, Stephen J. Forman, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4075.
https://doi.org/10.1182/blood-2019-123765
Published: 2019
Journal Articles

Cannabidiol Reduces Acute and Chronic Hyperalgesia in Humanized Sickle Mice

Varun Sagi, BS, Jianxun Lei, PhD, Stacy B Kiven, BS, Huy Tran, BS, Kalpna Gupta, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 77.
https://doi.org/10.1182/blood-2019-129706
Published: 2019
Journal Articles

First-in-Human Study of ET019003, a Next Generation Anti-CD19 T-Cell Therapy, in Patients with Relapsed/Refractory Diffuse Large B Cell Lymphoma (r/r DLBCL)

Pengcheng He, Hong Liu, Haibo Liu, Mina Luo, Hui Feng, Qijing Li, Qi Chang, Bingyi Shi, Cheng Liu
Journal: Blood
Blood (2019) 134 (Supplement_1): 2870.
https://doi.org/10.1182/blood-2019-131414
Published: 2019
Journal Articles

A Phase I/II Dose-Escalation Study of Thiotepa-Based Immunochemotherapy in Relapsed/Refractory Primary Central Nervous System Lymphoma; The Tier Trial

Christopher P Fox, MBChB(Hons), MRCP, FRCPath, PhD, Ayesha S Ali, MSc, Dorothee Auer, MD DM, PhD, Steffi Thust, MD FRCR, Aimee E Jackson, MSc, Louise Hopkins, BSc, MRes, Catherine Thomas, PhDBSc, Nicolas Martinez-Calle, MD MSc, Graham P. Collins, MA, MBBS, MRCP, FRCPath, DPhil, Shireen Kassam, MD, Josh Wright, MD, David Lewis, PhD FRCPath, BSc, Andres JM Ferreri, MD, Sridhar Chaganti, MDPhDMRCP,FRCPath, Jeffery Smith, MBChB BMedSci MRCP FRCPath, Kim Linton, MBChB PhD, Ian Chau, MD, Dominic J. Culligan, MD, Andrew Davies, MD PhD, Roderick Johnson, MD, Kate Cwynarski, PhDMD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2879.
https://doi.org/10.1182/blood-2019-122830
Published: 2019
Journal Articles

Transcranial Doppler Screening in Children with Sickle Cell Anemia Is Feasible in Central India and Reveals High Risk of Stroke

Dipty Jain, MD, Kavitha Ganesan, MBBS, Sati Sahota, Deepika S. Darbari, MD, Lakshmanan Krishnamurti, MD, Fenella Jane Kirkham, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2279.
https://doi.org/10.1182/blood-2019-131416
Published: 2019
Journal Articles

Efficacy of Caplacizumab in Patients with aTTP in the HERCULES Study According to Baseline Disease Severity

Paul Coppo, MD PhD, Spero Cataland, MD, Flora Peyvandi, MD PhD, Paul Knoebl, MD, Marie Scully, Johanna A. Kremer Hovinga, MD Prof, Ara Metjian, MD, Javier De La Rubia, Katerina Pavenski, MD, Hilde De Winter, MD, Rui de Passos Sousa, Filip Callewaert
Journal: Blood
Blood (2019) 134 (Supplement_1): 2366.
https://doi.org/10.1182/blood-2019-123720
Published: 2019
Journal Articles

Quantitative Modeling of Azacitidine Resistance in Patients with Myelodysplastic Syndrome Identifies Distinct Phenotypes of Disease Progression: Evidence for the Presence of a Disease Versus Native Clone Effect

Roman M Shapiro, MD, Adam R Stinchcombe, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1723.
https://doi.org/10.1182/blood-2019-130332
Published: 2019
Journal Articles

Clinical Activity of REGN1979, a Bispecific Human, Anti-CD20 x Anti-CD3 Antibody, in Patients with Relapsed/Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (B-NHL)

Rajat Bannerji, MD PhD, John N. Allan, MD, Jon E. Arnason, MD, Jennifer R. Brown, MD PhD, Ranjana H Advani, MD, Jeffrey A. Barnes, MD PhD, Stephen M Ansell, MD PhD, Susan M. O'Brien, MD, Julio Chavez, Johannes Duell, MD, Kevin A. David, MD, Peter Martin, FRCPC, MD MS, Robin M. Joyce, MD, Robert Charnas, PhD, Srikanth R. Ambati, MBBS, MD, Lieve Adriaens, PharmD, Melanie Ufkin, PhD, Min Zhu, PhD, Jingjin Li, PhD, Peter Gasparini, MS, Anfal Ibrahim, BS, Vladimir Jankovic, MD, Nathalie Fiaschi, PhD, Olulanu Aina, PhD, Wen Zhang, PhD, Raquel P. Deering, PhD, Sara Hamon, PhD, Gavin Thurston, PhD, Andrew J. Murphy, PhD, David M. Weinreich, MD, George D. Yancopoulos, MD PhD, Israel Lowy, MD PhD, David Sternberg, MD PhD, Max S. Topp, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 762.
https://doi.org/10.1182/blood-2019-122451
Published: 2019
Journal Articles

Experience with Axicabtagene Ciloleucel (Axi-cel) in Patients with Secondary CNS Involvement: Results from the US Lymphoma CAR T Consortium

N. Nora Bennani, MD, Matthew J. Maurer, MS, Loretta J. Nastoupil, MD MSc, Michael D. Jain, MD PhD, Julio C. Chavez, MD, Amanda F Cashen, MD, Saurabh Dahiya, MD, Lazaros J. Lekakis, MD, Patrick M Reagan, MD, Olalekan O. Oluwole, MBBS, MPH, Joseph P. McGuirk, DO, Abhinav Deol, MD, Alison R. Sehgal, MD, Andre Goy, MD, Brian T. Hill, MD, Khoan Vu, MD, Charalambos Andreadis, MD, Javier Munoz, MD MS, FACP, Aaron P. Rapoport, Julie M Vose, MDMBA, David B Miklos, MD PhD, Frederick L. Locke, MD, Sattva S Neelapu, MD, Yi Lin, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 763.
https://doi.org/10.1182/blood-2019-129097
Published: 2019