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Journal Articles

Machine Learning Unveils Proteotypic Mimicry in Genetically Defined SCN Variants

Sebastian Hesse, MD, Christoph Klein, MD PhD, Rappsilber Juri, Prof., Yoko Mizoguchi, Monika Linder, PhD, Piotr Grabowski, PhD, Zahra Alizadeh, PhD, Zahra Pourpak, MD PhD, Nima Rezaei, MD PhD, Sorin Iurian, MD PhD, Ekrem Unal, MD, Fabian Hauck, MD PhD, Ralf Zimmer, Prof., Gergely Csaba, PhD

Blood (2019) 134 (Supplement_1): 3580.

https://doi.org/10.1182/blood-2019-131136

Published: 2019

Journal Articles

Computational Systems Biology Models for the Identification of Metabolic Vulnerabilities in Multiple Myeloma

Luis Vitores V. Valcárcel, MSc, Raquel Ordoñez, PhD, Iñigo Apaolaza, MSc, Ana Valcárcel, Leire Garate, Cem Meydan, PhD, Bruno Paiva, PhD, Ari M Melnick, MD, Jesús San-Miguel, Francisco J. Planes, Xabier Agirre, PhD, Felipe Prosper, MD PhD

Blood (2019) 134 (Supplement_1): 3084.

https://doi.org/10.1182/blood-2019-123970

Published: 2019

Journal Articles

Transcriptomic Systems Biology Analyses with Buparlisib (BKM120) Pan PI3K Inhibition in Canine B Cell Lymphoma (BCL): Leveraging Comparative Oncology for Cancer Therapeutics and Biomarker Discovery

Ravi Dashnamoorthy, PhD, Afshin Beheshti, PhD, Sarah Cass, BSVM, Athena Kritharis, MD, Kristine Burgess, DVM, MS, Cheryl London, DVM, PhD DACVIM, Andrew M. Evens, DO, MSc

Blood (2018) 132 (Supplement 1): 4114.

https://doi.org/10.1182/blood-2018-99-118548

Published: 2018

Journal Articles

A Systems Biology Approach to Identify Mechanisms of Therapy Resistance in Multiple Myeloma

Rafael Renatino Canevarolo, PhD, Praneeth Reddy Sudalagunta, PhD, Maria D Coelho Siqueira Silva, MSc, Mark B. Meads, PhD, Priscilla Granados, Anders Berglund, Amit Kulkarni, PhD, Hongyue Dai, PhD, William S. Dalton, PhDMD, Ion Petre, PhD, Kenneth H. Shain, MD PhD, Ariosto Siqueira Silva, PhD

Blood (2018) 132 (Supplement 1): 3266.

https://doi.org/10.1182/blood-2018-99-118784

Published: 2018

Journal Articles

Systems Biology Analysis Identifies Targetable Vulnerability Networks to Proteasome Inhibitors in Multiple Myeloma

Mark B. Meads, PhD, Rafael Renatino Canevarolo, PhD, Praneeth Reddy Sudalagunta, PhD, Paula S. Oliveira, Dario M. Magaletti, Bin Fang, PhD, Maria D Coelho Siqueira Silva, MSc, Amit Kulkarni, PhD, Hongyue Dai, PhD, William S. Dalton, PhDMD, Ion Petre, PhD, John M. Koomen, PhD, Ariosto Siqueira Silva, PhD, Kenneth H. Shain, MD PhD

Blood (2018) 132 (Supplement 1): 950.

https://doi.org/10.1182/blood-2018-99-120269

Published: 2018

Journal Articles

Computational Integration to Model Tumor Dynamics in CLL Patients Treated with the Btk Inhibitor Ibrutinib (CompuTreatCLL): First Results of an Integrative Systems Biology Approach

Loic Ysebaert, MD PhD, Sarah Cadot, PhD, Salim Kanoun, MD, Soleakhena Ken, Christian Recher, MD PhD, François Malgouyres, Sebastien Gadat, Loic Dupre, PhD, Anne Quillet Mary, PhD

Blood (2017) 130 (Supplement 1): 2990.

https://doi.org/10.1182/blood.V130.Suppl_1.2990.2990

Published: 2017

Journal Articles

De Novo DNA Methylation Is Associated with Granulopoiesis and Megakaryopoiesis but Not Erythropoiesis

Jens Lichtenberg, PhD, Elisabeth F. Heuston, PhD, Stacie M. Anderson, NIH Intramural Sequencing Center, Cheryl A. Keller, PhD, Ross C. Hardison, PhD, David M. Bodine, PhD

Blood (2016) 128 (22): 3868.

https://doi.org/10.1182/blood.V128.22.3868.3868

Published: 2016

Journal Articles

Circulating microRNAs Predict the Initiation of NHL in a Novel In Vivo Model: Impact of Age and Sex Via a Systems Biology Approach

Afshin Beheshti, PhD, Charles Vanderburg, PhD, John Tyson Mcdonald, PhD, Hong Zhang, PhD, Andrew M. Evens, DO, MSc

Blood (2016) 128 (22): 4114.

https://doi.org/10.1182/blood.V128.22.4114.4114

Published: 2016

Journal Articles

Distinct Stress Responses of Bone Marrow Stromal Cell Subgroups Defined by Unbiased Single-Cell Mass-Cytometry Analysis

Nicolas Severe, PhD, Murat Karabacak, PhD, Ninib Baryawno, PhD, Karin Gustafsson, PhD, Youmna Sami Kfoury, PhD, Mehmet Toner, PhD, David T. Scadden, MD

Blood (2016) 128 (22): 430.

https://doi.org/10.1182/blood.V128.22.430.430

Published: 2016

Journal Articles

The Proteasome Inhibitor, Ixazomib, Combined with Novel Drug Combinations in T-Cell Lymphoma (TCL) and Hodgkin Lymphoma (HL): Identification of Key Genes and Signaling Pathways Via a Novel Systems Biology Approach

Frank C. Passero, Jr., MD, Ravi Dashnamoorthy, PhD, Afshin Beheshti, PhD, Lynn Hlatky, PhD, Nassera Abermil, MS, PharmD, Michael E Coyle, MD, Jaya Sharma, MD MBBS, Andrew M. Evens, DO, MSc

Blood (2015) 126 (23): 2753.

https://doi.org/10.1182/blood.V126.23.2753.2753

Published: 2015

Journal Articles

The PI3 Kinase (PI3K) Inhibitor, Buparlisib/BKM120, in B-Cell, T-Cell and Hodgkin Lymphoma Cell Lines: Cell Death Studies and Examination of Genomic Pathway Analyses Via a Systems Biology Approach

Michael E Coyle, MD, Ravi Dashnamoorthy, PhD, Afshin Beheshti, PhD, Andrew M. Evens, DO, MSc

Blood (2015) 126 (23): 1555.

https://doi.org/10.1182/blood.V126.23.1555.1555

Published: 2015

Journal Articles

Comparison of Expression and Epigenetic Profiles in Human and Mouse Erythropoiesis and Megakaryopoiesis Using a Systems Biology Model

Jens Lichtenberg, PhD, Elisabeth F. Heuston, PhD, Cheryl A. Keller, PhD, Ross C. Hardison, PhD, David M. Bodine, PhD

Blood (2015) 126 (23): 2383.

https://doi.org/10.1182/blood.V126.23.2383.2383

Published: 2015

Journal Articles

The Impact of Age and Sex in DLBCL: Determination of Biologic Dynamics and Delineation of Inter-Connected Signaling Networks Via a Systems Biology Analysis

Afshin Beheshti, PhD, Donna S Neuberg, ScD, J. Tyson McDonald, PhD, Andrew M. Evens, DO, MSc

Blood (2015) 126 (23): 2672.

https://doi.org/10.1182/blood.V126.23.2672.2672

Published: 2015

Journal Articles

A Systems Biology Model for the Coagulation Network in Non-Bleeding State Describes Baseline Activity of Coagulation

Dooyoung Lee, PhD, Satyaprakash Nayak, PhD, Debra Pittman, Steven Arkin, MD, Steven Martin, PhD, Anne C Heatherington, PhD, Paolo Vicini, PhD, Fei Hua, PhD

Blood (2014) 124 (21): 4238.

https://doi.org/10.1182/blood.V124.21.4238.4238

Published: 2014

Journal Articles

Leukemia Cell Differentiation upon Targeted Therapy Revealed By a Systems Biology Approach

Yulin Li, MD PhD, Jun Seita, MD, PhD, Dean W Felsher, MD PhD, David Dill, PhD

Blood (2014) 124 (21): 5202.

https://doi.org/10.1182/blood.V124.21.5202.5202

Published: 2014

Journal Articles

Systems Biology and Epigenetic Mechanisms in Erythropoiesis

Merav Socolovsky, MBBS, PhD

Blood (2013) 122 (21): SCI-11.

https://doi.org/10.1182/blood.V122.21.SCI-11.SCI-11

Published: 2013

Journal Articles

Systems Biology to Predict Platelet Function

Scott L. Diamond, PhD

Blood (2010) 116 (21): SCI-38.

https://doi.org/10.1182/blood.V116.21.SCI-38.SCI-38

Published: 2010

Journal Articles

High-Throughput Sequencing of the Human Platelet Transcriptome

Paul F Bray, MD, Paolo M. Fortina, MD, PhD, Srikanth Nagalla, MD, MS, Kathleen Delgrosso, Adam Ertel, Isidore Rigoutsos, Steven E McKenzie, MD, PhD

Blood (2010) 116 (21): 481.

https://doi.org/10.1182/blood.V116.21.481.481

Published: 2010

Journal Articles

Hematopoiesis and its disorders: a systems biology approach

Zakary L. Whichard, Casim A. Sarkar, Marek Kimmel, Seth J. Corey

Blood (2010) 115 (12): 2339–2347.

https://doi.org/10.1182/blood-2009-08-215798

Published: 2010

Journal Articles

A Systems Biology Approach to Study the Acquisition of Adult Repopulating Potential During Hematopoietic Stem Cell Ontogeny.

Shannon McKinney-Freeman, PhD, Hu Li, PhD, Matthew Curran, Sabine Loewer, PhD, Catherine Spina, Olaia Naveiras, MD, James J. Collins, PhD, George Q. Daley, MD, PhD

Blood (2009) 114 (22): 1479.

https://doi.org/10.1182/blood.V114.22.1479.1479

Published: 2009

NARROW

Machine Learning Unveils Proteotypic Mimicry in Genetically Defined SCN Variants

Computational Systems Biology Models for the Identification of Metabolic Vulnerabilities in Multiple Myeloma

Transcriptomic Systems Biology Analyses with Buparlisib (BKM120) Pan PI3K Inhibition in Canine B Cell Lymphoma (BCL): Leveraging Comparative Oncology for Cancer Therapeutics and Biomarker Discovery

A Systems Biology Approach to Identify Mechanisms of Therapy Resistance in Multiple Myeloma

Systems Biology Analysis Identifies Targetable Vulnerability Networks to Proteasome Inhibitors in Multiple Myeloma

Computational Integration to Model Tumor Dynamics in CLL Patients Treated with the Btk Inhibitor Ibrutinib (CompuTreatCLL): First Results of an Integrative Systems Biology Approach

De Novo DNA Methylation Is Associated with Granulopoiesis and Megakaryopoiesis but Not Erythropoiesis

Circulating microRNAs Predict the Initiation of NHL in a Novel In Vivo Model: Impact of Age and Sex Via a Systems Biology Approach

Distinct Stress Responses of Bone Marrow Stromal Cell Subgroups Defined by Unbiased Single-Cell Mass-Cytometry Analysis

The Proteasome Inhibitor, Ixazomib, Combined with Novel Drug Combinations in T-Cell Lymphoma (TCL) and Hodgkin Lymphoma (HL): Identification of Key Genes and Signaling Pathways Via a Novel Systems Biology Approach

The PI3 Kinase (PI3K) Inhibitor, Buparlisib/BKM120, in B-Cell, T-Cell and Hodgkin Lymphoma Cell Lines: Cell Death Studies and Examination of Genomic Pathway Analyses Via a Systems Biology Approach

Comparison of Expression and Epigenetic Profiles in Human and Mouse Erythropoiesis and Megakaryopoiesis Using a Systems Biology Model

The Impact of Age and Sex in DLBCL: Determination of Biologic Dynamics and Delineation of Inter-Connected Signaling Networks Via a Systems Biology Analysis

A Systems Biology Model for the Coagulation Network in Non-Bleeding State Describes Baseline Activity of Coagulation

Leukemia Cell Differentiation upon Targeted Therapy Revealed By a Systems Biology Approach

Systems Biology and Epigenetic Mechanisms in Erythropoiesis

Systems Biology to Predict Platelet Function

High-Throughput Sequencing of the Human Platelet Transcriptome

Hematopoiesis and its disorders: a systems biology approach

A Systems Biology Approach to Study the Acquisition of Adult Repopulating Potential During Hematopoietic Stem Cell Ontogeny.

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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