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Journal Articles

Discovery of a Novel Dihydroorotate Dehydrogenase Inhibitor That Induces Differentiation and Overcomes Ara-C Resistance of Acute Myeloid Leukemia Cells

Satoshi Kitazawa, PhD, Yukiko Ishii, PhD, Keiko Makita-Suzuki, Koichi Saito, PhD, Kensuke Takayanagi, Hiromi Sugihara, Shun Matsuda, PhD, Takayuki Yamakawa, PhD, Yasuhiro Tsutsui, Tadashi Tanaka, Tomohisa Hatta, PhD, Tohru Natsume, PhD, Toru Kondo, PhD, Yuichi Ishikawa, MD PhD, Shinji Hagiwara, PhD, Hitoshi Kiyoi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2663.
https://doi.org/10.1182/blood-2019-121869
Published: 2019
Journal Articles

AG-636 for the Treatment of Adults with Advanced Lymphoma: Initiation of a Phase 1 Clinical Study

Scott F. Huntington, MD MPH, Avyakta Kallam, MD, Frank G. Basile, MD, Danielle Ulanet, Huansheng Xu, PhD, Feng Yin, PhD, Michelle Mobilia, BS, Michael Cooper, MD, Bijal Shah, MD, John P. Leonard, MD, Gottfried R. von Keudell, MD PhD, Ajay K. Gopal, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1286.
https://doi.org/10.1182/blood-2019-123420
Published: 2019
Journal Articles

Leflunomide Inhibits c-Myc Signaling and Impairs Myeloma Cell Growth

Ralf Buettner, PhD, Corey James Morales, BA, BS, Enrico Caserta, PhD, Domenico Viola, BS, Joycelynne M. Palmer, PhD, Xiwei Wu, PhD, Nagarajan Vaidehi, PhD, Hongzhi Li, PhD, Tim Synold, PhD, Amrita Krishnan, MD, Flavia Pichiorri, PhD, Michael Rosenzweig, MD, Steven T. Rosen, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4426.
https://doi.org/10.1182/blood.V130.Suppl_1.4426.4426
Published: 2017
Journal Articles

Repurposing Leflunomide for Multiple Myeloma Treatment

Ralf Buettner, PhD, Corey Morales, BA, BS, Natalie Perret, Joycelynne Palmer, PhD, Amrita Krishnan, Michael Rosenzweig, MD, Steven T. Rosen, MD
Journal: Blood
Blood (2016) 128 (22): 5667.
https://doi.org/10.1182/blood.V128.22.5667.5667
Published: 2016