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Journal Articles

GDF1 Regulation of Ceramide Metabolism Restores Effective Hematopoiesis in Myelodysplastic Syndrome

Brian Barth, PhD MS, BS, Weiyuan Wang, Emily Sullivan, Vasiliki Papakotsi, Andrea Cote, Paul Toran, PhD, Sarah Walker, PhD, Thomas P Loughran, Jr., MD

Blood (2019) 134 (Supplement_1): 1700.

https://doi.org/10.1182/blood-2019-131623

Published: 2019

Journal Articles

Clinical ALK5 Inhibitor, Vactosertib, Reverses TGFβ-1 Stimulated Smad-2 Driven Ineffective Hematopoiesis in MDS

Srinivas Aluri, Kimo Bachiashvili, MD, Anjali Budhathoki, MD, Tushar D Bhagat, PhD, Gaurav S Choudhary, PhD, Shanisha Gordon, Nandini Ramachandra, Kith Pradhan, PhD, Shahina Maqbool, Aditi Shastri, MD, Jung Im Huh, Sunjin Hwang, Kim Seong-Jin, PhD, Hui Zhang, Britta Will, PhD, Amittha Wickrema, PhD, Ulrich G. Steidl, MD PhD, Amit Verma, MBBS

Blood (2019) 134 (Supplement_1): 2990.

https://doi.org/10.1182/blood-2019-127561

Published: 2019

Journal Articles

Variable Expression Levels of the Hematopoietic Stem Cell Surface Antigen ESAM Depict Heterogeneity and Fluctuations in Leukemic Stem Cells

Yasuhiro Shingai, Takafumi Yokota, MD PhD, Tomoaki Ueda, Yukiko Doi, Tomohiko Ishibashi, Akira Tanimura, Michiko Ichii, MD PhD, Sachiko Ezoe, Hirohiko Shibayama, MD PhD, Kenji Oritani, MD PhD, Yuzuru Kanakura, MD PhD

Blood (2017) 130 (Supplement 1): 1252.

https://doi.org/10.1182/blood.V130.Suppl_1.1252.1252

Published: 2017

Journal Articles

Inhibiting TGF-Beta Signaling in the Tumor Micro-Environment Enhances the Cytotoxic Function of Adoptive NK Cells

Folashade Otegbeye, MBChB, MPH, Evelyn Ojo, BS, Nathan Mackowski, BA, Stephen Moreton, David N. Wald, MD PhD

Blood (2016) 128 (22): 2160.

https://doi.org/10.1182/blood.V128.22.2160.2160

Published: 2016

Journal Articles

Preclinical Efficacy of TGF-Beta Receptor I Kinase Inhibitor, Galunisertib, in Myelofibrosis

Lanzhu Yue, PhD, Matthias Bartenstein, Wanke Zhao, Wan-Ting Ho, Ling Zhang, MD, Franck Rapaport, PhD, Ross L. Levine, MD, Zonghong Shao, Zhizhuang Joe Zhao, PhD, Amit Verma, Pearlie K Epling-Burnette, PhD

Blood (2015) 126 (23): 603.

https://doi.org/10.1182/blood.V126.23.603.603

Published: 2015

Journal Articles

Activation of NK and CD8+ T-Cells with a Novel IL-15 and TGF-Beta Receptor Fusion Protein Confers Anti-Tumor Immunity

Spencer Ng, B.Sc., Jiusheng Deng, PhD, Raghavan Chinndurai, PhD, Shala Yuan, MS, Andrea Pennati, PhD, Jacques Galipeau, MD

Blood (2015) 126 (23): 3421.

https://doi.org/10.1182/blood.V126.23.3421.3421

Published: 2015

Journal Articles

Up-Regulation of Prok-2 in Granulocytes Is Present BOTH in MGUS and MM

Alessandra Romano, MD PhD, Vittorio Simeon, Piera La Cava, Nunziatina Laura Parrinello, PhD, Alessia La Fauci, Calogero Vetro, Daniele Tibullo, Cesarina Giallongo, Maide Cavalli, MD, Annalisa Chiarenza, MD PhD, Concetta Conticello, MD, Pellegrino Musto, MD, Francesco Di Raimondo, MD

Blood (2014) 124 (21): 5694.

https://doi.org/10.1182/blood.V124.21.5694.5694

Published: 2014

Journal Articles

Expression Of Mutant Spliceosomal Protein SF3B1 Results In Dysregulated Hematopoietic Maturation

Alexander C. Minella, MD, Oscar Ramirez, PhD, Yanfei Xu, Ph.D, Tushar Murthy, Xiaodong Yang, PhD, Manoj M Pillai, MD

Blood (2013) 122 (21): 2773.

https://doi.org/10.1182/blood.V122.21.2773.2773

Published: 2013

Journal Articles

Epigenomic Evolution In Diffuse Large B-Cell Lymphomas

Heng Pan, BA, Yanwen Jiang, PhD, David Redmond, Kui Nie, PhD, Leandro Cerchietti, MD, Rita Shaknovich, MD/PhD, Ari M. Melnick, MD, Wayne Tam, MD, PhD, Olivier Elemento, PhD

Blood (2013) 122 (21): 634.

https://doi.org/10.1182/blood.V122.21.634.634

Published: 2013

Journal Articles

High-Resolution Chromatin Immunoprecipitation (ChIP) Sequencing Identifies Novel Binding Targets and Prognostic Role for SOX11 in Mantle Cell Lymphoma

Pei-Yu Kuo, MS, Violetta V. Leshchenko, PhD, Tobias A. Gellen, Netha Ulahannan, MS, Paul Zumbo, BA, BS, Christopher E. Mason, PhD, Wyndham H. Wilson, MD, PhD, Adrian Wiestner, MD, PhD, K. Stephen Suh, PhD, Andre Goy, MD, David T. Yang, MD, Brad S. Kahl, MD, Randy D. Gascoyne, MD, Ari Melnick, MD, Samir Parekh, MD

Blood (2011) 118 (21): 585.

https://doi.org/10.1182/blood.V118.21.585.585

Published: 2011

Journal Articles

Genome-Wide Association Study for Determinants of Acute Graft Vs Host Disease (aGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation: Development of 7 SNP Model Predicting aGVHD

Eunkyung Park, Song Joo Yang, Inho Kim, Eun Hyung Jeon, Seonyang Park, MD

Blood (2011) 118 (21): 1010.

https://doi.org/10.1182/blood.V118.21.1010.1010

Published: 2011

Journal Articles

Evidence of Common Mechanisms Underlying the Survival Advantage of the PIG-A mutant and 13q- Hematopoietic Stem Cell Clones In Patients with Immune-Mediated Bone Marrow Failure

Kohei Hosokawa, MD, Takamasa Katagiri, Bsc, Naomi Sugimori, MD, PhD, Zhirong Qi, MD, Luis J. Espinoza, MD, Masashi Sanada, MD, PhD, Seishi Ogawa, MD, PhD, Shinji Nakao, MD, PhD

Blood (2010) 116 (21): 4429.

https://doi.org/10.1182/blood.V116.21.4429.4429

Published: 2010

Journal Articles

Differential Expression of Transforming Growth Factor Beta Receptor 2 (TGFβR2) In Diabetic CD34+ Cells: Implications for Vascular Repair

Ashay Bhatwadekar, Valerie Stepps, MS, Maria B Grant, MD, Stephen H. Bartelmez, PhD

Blood (2010) 116 (21): 4795.

https://doi.org/10.1182/blood.V116.21.4795.4795

Published: 2010

Journal Articles

Overexpression of the TGF-Beta Modulator . Bambi Promotes Hematopoetic Stem Cell Proliferation.

Rui Mao, Olga Sirin, BS/MS, Margaret Goodell, PhD

Blood (2009) 114 (22): 1446.

https://doi.org/10.1182/blood.V114.22.1446.1446

Published: 2009

Journal Articles

A2A or Beta-2 Adrenergic Receptor Agonist Synergies Induce Distinct Patterns of Gene Expression Relevant to Multiple Myeloma Cell Survival.

Winnie F. Tam, PhD, Richard J Rickles, PhD, Thomas Giordano, Alexis Borisy, Margaret S. Lee, PhD

Blood (2009) 114 (22): 3831.

https://doi.org/10.1182/blood.V114.22.3831.3831

Published: 2009

Journal Articles

Sezary Syndrome Aberrant Expression of CD26 On CD4+, CD25+, FOXP3+ T Lymphocytes and Prognostic Significance.

Giorgio Corinaldesi, MD, PhD, Christian Corinaldesi, MD

Blood (2009) 114 (22): 4244.

https://doi.org/10.1182/blood.V114.22.4244.4244

Published: 2009

Journal Articles

Dysregulation of TGF-Beta Stimulated Smad Signaling Is Seen in Myelodysplasia and Points to the Potential Therapeutic Efficacy of TGF-Beta Receptor I Kinase Inhibition in Low Grade Disease.

Blood (2009) 114 (22): 737.

https://doi.org/10.1182/blood.V114.22.737.737

Published: 2009

Journal Articles

Association of Genetic Polymorphisms in the TGF-β Pathway with the Acute Chest Syndrome of Sickle Cell Anemia.

Carolina Martinez-Castaldi, MD, Vikki G. Nolan, MPH, Clinton T. Baldwin, PhD, Lindsay A. Farrer, PhD, Martin H. Steinberg, MD, Elizabeth S. Klings, MD

Blood (2007) 110 (11): 2247.

https://doi.org/10.1182/blood.V110.11.2247.2247

Published: 2007

Journal Articles

SB431542, a TGF-Beta Receptor Kinase Inhibitor, Restores Bone Formation Which Ameliorates Myeloma-Induced Microenvironment.

Kyoko Takeuchi, MD, Masahiro Abe, MD, Asuka Oda, MT, Hiroe Amou, MT, Masahiro Hiasa, DDS, Jin Asano, MD, Kenichi Kitazoe, MD, Toshihiro Hashimoto, MD, Shuji Ozaki, MD, Shinsuke Kido, PhD, Daisuke Inoue, MD, Toshio Matsumoto, MD

Blood (2006) 108 (11): 3479.

https://doi.org/10.1182/blood.V108.11.3479.3479

Published: 2006

Journal Articles

Genetic Modifiers of Cerebrovascular Large Vessel Stenosis in Sickle Cell Anemia.

M. Catherine Driscoll, MD, Joseph Devaney, PhD, Heather Gordish, PhD, Caterina Minniti, MD, Eric P. Hoffman, PhD

Blood (2004) 104 (11): 1658.

https://doi.org/10.1182/blood.V104.11.1658.1658

Published: 2004

NARROW

GDF1 Regulation of Ceramide Metabolism Restores Effective Hematopoiesis in Myelodysplastic Syndrome

Clinical ALK5 Inhibitor, Vactosertib, Reverses TGFβ-1 Stimulated Smad-2 Driven Ineffective Hematopoiesis in MDS

Variable Expression Levels of the Hematopoietic Stem Cell Surface Antigen ESAM Depict Heterogeneity and Fluctuations in Leukemic Stem Cells

Inhibiting TGF-Beta Signaling in the Tumor Micro-Environment Enhances the Cytotoxic Function of Adoptive NK Cells

Preclinical Efficacy of TGF-Beta Receptor I Kinase Inhibitor, Galunisertib, in Myelofibrosis

Activation of NK and CD8+ T-Cells with a Novel IL-15 and TGF-Beta Receptor Fusion Protein Confers Anti-Tumor Immunity

Up-Regulation of Prok-2 in Granulocytes Is Present BOTH in MGUS and MM

Expression Of Mutant Spliceosomal Protein SF3B1 Results In Dysregulated Hematopoietic Maturation

Epigenomic Evolution In Diffuse Large B-Cell Lymphomas

High-Resolution Chromatin Immunoprecipitation (ChIP) Sequencing Identifies Novel Binding Targets and Prognostic Role for SOX11 in Mantle Cell Lymphoma

Genome-Wide Association Study for Determinants of Acute Graft Vs Host Disease (aGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation: Development of 7 SNP Model Predicting aGVHD

Evidence of Common Mechanisms Underlying the Survival Advantage of the PIG-A mutant and 13q- Hematopoietic Stem Cell Clones In Patients with Immune-Mediated Bone Marrow Failure

Differential Expression of Transforming Growth Factor Beta Receptor 2 (TGFβR2) In Diabetic CD34+ Cells: Implications for Vascular Repair

Overexpression of the TGF-Beta Modulator . Bambi Promotes Hematopoetic Stem Cell Proliferation.

A2A or Beta-2 Adrenergic Receptor Agonist Synergies Induce Distinct Patterns of Gene Expression Relevant to Multiple Myeloma Cell Survival.

Sezary Syndrome Aberrant Expression of CD26 On CD4+, CD25+, FOXP3+ T Lymphocytes and Prognostic Significance.

Dysregulation of TGF-Beta Stimulated Smad Signaling Is Seen in Myelodysplasia and Points to the Potential Therapeutic Efficacy of TGF-Beta Receptor I Kinase Inhibition in Low Grade Disease.

Association of Genetic Polymorphisms in the TGF-β Pathway with the Acute Chest Syndrome of Sickle Cell Anemia.

SB431542, a TGF-Beta Receptor Kinase Inhibitor, Restores Bone Formation Which Ameliorates Myeloma-Induced Microenvironment.

Genetic Modifiers of Cerebrovascular Large Vessel Stenosis in Sickle Cell Anemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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