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Journal Articles

The Effects of Antiplatelet Agents on Endocytosis

Harvey G. Roweth, BSc,PhD, Michael Malloy, BS, Jodi A. Forward, BS, Julia Ceglowski, BA, Robert C. Flaumenhaft, MD PhD, Joseph E. Italiano, Jr., BS, PhD, Elisabeth Battinelli, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1058.
https://doi.org/10.1182/blood-2019-131912
Published: 2019
Journal Articles

Role for PARS and Thrombin-Gpibα Interaction for Thrombin Induced Procoagulant Platelet Formation

Morgane Bourcy, PhD, Leonardo Pasalic, MBBS, BSc, Samuel Wang, Heather Campbell, BSc, Hai Po Helena Liang, PhD, Vivien Chen, PhD FRACP, FRCPA, MBBS
Journal: Blood
Blood (2017) 130 (Supplement 1): 3607.
https://doi.org/10.1182/blood.V130.Suppl_1.3607.3607
Published: 2017
Journal Articles

Expression of Functional Human Proteinase Activated Receptor (PAR)-1 on Mouse Platelets

Alessandro Zarpellon, PhD, Taisuke Kanaji, MD, Sachiko Kanaji, MD PhD, Yosuke Morodomi, MD PhD, Zaverio M. Ruggeri, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 451.
https://doi.org/10.1182/blood.V130.Suppl_1.451.451
Published: 2017
Journal Articles

PAR1 Antagonists Development and Clinical Utility

Shaun Coughlin, MD PhD
Journal: Blood
Blood (2016) 128 (22): SCI-10.
https://doi.org/10.1182/blood.V128.22.SCI-10.SCI-10
Published: 2016
Journal Articles

The Common PAR4 Ala120Thr Variant Has a Major Effect on Platelet Reactivity to Thrombin and These Effects Are Enhanced with PAR1 and P2Y12 Inhibition

Michael J. Whitley, Joanne Vesci, Michael Holinstat, PhD, Leonard C. Edelstein, PhD, Paul F. Bray, MD
Journal: Blood
Blood (2016) 128 (22): 709.
https://doi.org/10.1182/blood.V128.22.709.709
Published: 2016
Journal Articles

Parmodulins inhibit thrombus formation without inducing endothelial injury caused by vorapaxar

Omozuanvbo Aisiku, Christian G. Peters, Karen De Ceunynck, Chandra C. Ghosh, James R. Dilks, Susanna F. Fustolo-Gunnink, Mingdong Huang, Chris Dockendorff, Samir M. Parikh, Robert Flaumenhaft
Journal: Blood
Blood (2015) 125 (12): 1976–1985.
https://doi.org/10.1182/blood-2014-09-599910
Published: 2015
Includes: Supplemental data
Journal Articles

Identification of a Racially Dimorphic Variant in the Human Platelet PAR4 Thrombin Receptor Altering Platelet Function and Pharmacologic Inhibition

Leonard C. Edelstein, PhD, Lukas M Simon, Cory R Lindsay, PhD, Xiango Kong, MD, Raul Teruel Montoya, PhD, Benjamin E Tourdot, PhD, Edward Chen, PhD, Lin Ma, Shaun R Coughlin, PhD, Marvin T. Nieman, PhD, Michael Holinstat, PhD, Chad Shaw, PhD, Paul F Bray, MD
Journal: Blood
Blood (2014) 124 (21): 1434.
https://doi.org/10.1182/blood.V124.21.1434.1434
Published: 2014
Journal Articles

Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race

Leonard C. Edelstein, Lukas M. Simon, Cory R. Lindsay, Xianguo Kong, Raúl Teruel-Montoya, Benjamin E. Tourdot, Edward S. Chen, Lin Ma, Shaun Coughlin, Marvin Nieman, Michael Holinstat, Chad A. Shaw, Paul F. Bray
Journal: Blood
Blood (2014) 124 (23): 3450–3458.
https://doi.org/10.1182/blood-2014-04-572479
Published: 2014
Includes: Supplemental data
Journal Articles

Racial Differences In Thrombin-Induced Human Platelet PAR4 Reactivity

Leonard C. Edelstein, PhD, Lukas M Simon, Raul Teruel Montoya, Ph.D., Michael Holinstat, PhD, Edward Chen, PhD, Angela Bergeron Woodley, BS, Xiango Kong, MD, Srikanth Nagalla, MD, MS, Narla Mohandas, D.Sc., David Cohen, MD, PhD, Jing-fei Dong, MD, PhD, Chad A Shaw, PhD, Paul F Bray, MD
Journal: Blood
Blood (2013) 122 (21): 1054.
https://doi.org/10.1182/blood.V122.21.1054.1054
Published: 2013