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Journal Articles

Heme Overload Triggers Xanthine Oxidase Release and Mediates the Inflammatory Response

Heidi M Schmidt, BSE, Eric Kelley, PhD, Adam Straub, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3529.
https://doi.org/10.1182/blood-2019-130274
Published: 2019
Journal Articles

Results of a Phase 1, Dose-Escalation Study of FF-10501-01 in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML) or Hypomethylating Agent (HMA)-Resistant Myelodysplastic Syndrome (MDS)

Guillermo Garcia-Manero, MD, Michael R. Kurman, MD, Courtney D. DiNardo, MD MSc, Naveen Pemmaraju, MD, Yesid Alvarado, MD, Kiran Naqvi, MD MPH, Farhad Ravandi, MD, Elias J. Jabbour, MD, Ricardo Delumpa, BSN, Timothy Madden, PhD, Gary Maier, PhD, Hiroyuki Iwamura, PhD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1438.
https://doi.org/10.1182/blood-2018-99-116613
Published: 2018
Journal Articles

Proteometabolomics of Melphalan Resistance in Multiple Myeloma

David C. Koomen, BS, Joy D. Guingab, PhD, Paula S. Oliveira, Bin Fang, PhD, Min Liu, PhD, Eric A. Welsh, PhD, Mark B. Meads, PhD, Tuan Nguyen, Laurel E. Meke, Steven A. Eschrich, PhD, Timothy J. Garrett, PhD, John M. Koomen, PhD, Kenneth H. Shain, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5619.
https://doi.org/10.1182/blood-2018-99-117747
Published: 2018
Journal Articles

Phase 1 Results of FF-10501-01, a Novel Inosine 5'-Monophosphate Dehydrogenase Inhibitor, in Advanced Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS), Including Hypomethylating Agent (HMA) Failures

Guillermo Garcia-Manero, MD, Hui Yang, MD PhD, Zhihong Fang, Hagop M. Kantarjian, MD, Courtney D. DiNardo, MD MSCE, Elias J. Jabbour, MD, Naveen Pemmaraju, MD, Naval Daver, MD, Ricardo Delumpa, RN, Christopher Loiselle, RN, Silvia Rivera, MS, Kristin Anderson, BS, Brittany Yearby, BS, Susan Denton, RN, Whitney Smith, BS, Kathleen Tiefenwerth, RN, Hiroyuki Iwamura, Dphil, Teletha Gipson, PhD, Michele Rosner, MS, Thomas J. Myers, MD, Linda J. Paradiso, DVM, MBA
Journal: Blood
Blood (2016) 128 (22): 1640.
https://doi.org/10.1182/blood.V128.22.1640.1640
Published: 2016
Journal Articles

Metabolic Analysis of Red Blood Cells Stored at High Temperature

James T. Yurkovich, Daniel C. Zielinski, PhD, Giuseppe Paglia, PhD, Ottar Rolfsson, PhD, Olafur E. Sigurjónsson, PhD, Aarash Bordbar, PhD, Bernhard Palsson, PhD
Journal: Blood
Blood (2016) 128 (22): 3848.
https://doi.org/10.1182/blood.V128.22.3848.3848
Published: 2016
Journal Articles

Biomarkers defining the metabolic age of red blood cells during cold storage

e-blood
Giuseppe Paglia, Angelo D’Alessandro, Óttar Rolfsson, Ólafur E. Sigurjónsson, Aarash Bordbar, Sirus Palsson, Travis Nemkov, Kirk C. Hansen, Sveinn Gudmundsson, Bernhard O. Palsson
Journal: Blood
Blood (2016) 128 (13): e43–e50.
https://doi.org/10.1182/blood-2016-06-721688
Published: 2016
Includes: Supplemental data
Journal Articles

Excessive Nitric Oxide Production of CGD Neutrophils Induces the Down-Regulation of NOS3 and EDN1 Expression in Human Endothelial Cells

Akari Utsunomiya, MD, Miyuki Tsumura, PhD, Norioki Ohno, MDPhD, Mizuka Miki, MD PhD, Satoshi Okada, MD PhD, Hiroshi Kawaguchi, MDPhD, Kazuhiro Nakamura, MD PhD, Masao Kobayashi, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2726.
https://doi.org/10.1182/blood.V124.21.2726.2726
Published: 2014
Journal Articles

Hsp90 at the Hub of Metabolic Homeostasis in Malignant B Cells

Nieves Calvo-Vidal, PhD, Jayeshkumar Patel, MS, Jan Krumsiek, PhD, Thibault Dupont, Rebecca Goldstein, BA, Shao Ning Yang, MS, Ari Melnick, MD, Gabriela Chiosis, PhD, Leandro Cerchietti, MD
Journal: Blood
Blood (2014) 124 (21): 1764.
https://doi.org/10.1182/blood.V124.21.1764.1764
Published: 2014
Journal Articles

Serum Metabolomics Uncovers a New Therapeutic Target in Diffuse Large B Cell Lymphoma (DLBCL)

Leandro Cerchietti, MD, Chen Qiuying, PhD, ShaoNing Yang, MS, Wang Chunjie, MS, Steven Gross, PhD
Journal: Blood
Blood (2012) 120 (21): 1648.
https://doi.org/10.1182/blood.V120.21.1648.1648
Published: 2012
Journal Articles

Metabolic Profiling in Sickle Cell Disease

Borys Hrinczenko, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 4837.
https://doi.org/10.1182/blood.V118.21.4837.4837
Published: 2011
Journal Articles

Nitrite Is Reduced to Nitric Oxide by Xanthine Oxidoreductase and Nitric Oxide Synthase in the Erythrocyte Membrane in Hypoxemia.

Krishnaraj S. Rathod, BMedSci, Andrew J. Webb, MBBS, Matthew J. Lovell, MBBS, Florence Lecomte, MA, Amrita Ahluwalia, PhD
Journal: Blood
Blood (2006) 108 (11): 1560.
https://doi.org/10.1182/blood.V108.11.1560.1560
Published: 2006
Journal Articles

Low-Dose Recombinante Urate Oxidase (Rasburicase) Is Effective in Treating Hyperuricemia in Patients with Hematologic Malignancies.

S. Trifilio, A. Evens, L. Gordon, S. Singhal, M. Tallman, J. Mehta
Journal: Blood
Blood (2005) 106 (11): 3123.
https://doi.org/10.1182/blood.V106.11.3123.3123
Published: 2005
Journal Articles

Low-Dose Recombinante Urate Oxidase (Rasburicase) Is Effective in Hyperuricemia.

S. Trifilio, M. Tallman, S. Singhal, L. Gordon, A. Evens, J. Mehta
Journal: Blood
Blood (2004) 104 (11): 3312.
https://doi.org/10.1182/blood.V104.11.3312.3312
Published: 2004
Journal Articles

Autooxidation as a basis for altered function by polymorphonuclear leukocytes

RL Baehner, LA Boxer, JM Allen, J Davis
Journal: Blood
Blood (1977) 50 (2): 327–335.
https://doi.org/10.1182/blood.V50.2.327.327
Published: 1977
Journal Articles

Absorption of Hemoglobin Iron: The Role of Xanthine Oxidase in the Intestinal Heme-Splitting Reaction

R. BEN DAWSON, M.D., SHEILA RAFAL, M.D., LEWIS R. WEINTRAUB, B.S.
Journal: Blood
Blood (1970) 35 (1): 94–103.
https://doi.org/10.1182/blood.V35.1.94.94
Published: 1970