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Journal Articles

Heme Overload Triggers Xanthine Oxidase Release and Mediates the Inflammatory Response

Heidi M Schmidt, BSE, Eric Kelley, PhD, Adam Straub, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3529.
https://doi.org/10.1182/blood-2019-130274
Published: 2019
Journal Articles

The Role of SOD2 in Maintaining Endothelial Cell Function in SCD

Atinuke Dosunmu-Ogunbi, Yingze Zhang, PhD, Seyed Mehdi Nouraie, PhD MD, Adam Straub, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3563.
https://doi.org/10.1182/blood-2019-131238
Published: 2019
Journal Articles

A Retrospective Review of Mercaptopurine Metabolism Reveals High Rate of Patients with Suboptimal Metabolites Successfully Corrected with Allopurinol

Lauren Marie Vasta, MD, Richard C Zanetti, MD, Dina S. Parekh, MD, Anne B. Warwick, MD MPH, Kenneth Lieuw, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3878.
https://doi.org/10.1182/blood-2019-126184
Published: 2019
Journal Articles

A Potential Mechanism for the Antioxidant Compound Kushen Injection Targeting the ROS Signaling Pathway in Acute Myeloid Leukemia

Yanxia Jin, PhD, Qian Yang, Li Liang, Lu Ding, Yuxing Liang, Dongdong Zhang, Tian Yang, Mingfeng Zhao, MD PhD, Fuling Zhou
Journal: Blood
Blood (2018) 132 (Supplement 1): 5221.
https://doi.org/10.1182/blood-2018-99-114066
Published: 2018
Journal Articles

Excessive Nitric Oxide Production of CGD Neutrophils Induces the Down-Regulation of NOS3 and EDN1 Expression in Human Endothelial Cells

Akari Utsunomiya, MD, Miyuki Tsumura, PhD, Norioki Ohno, MDPhD, Mizuka Miki, MD PhD, Satoshi Okada, MD PhD, Hiroshi Kawaguchi, MDPhD, Kazuhiro Nakamura, MD PhD, Masao Kobayashi, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2726.
https://doi.org/10.1182/blood.V124.21.2726.2726
Published: 2014
Journal Articles

Xanthine Oxidase Mediates High Fat Diet-Induced Vascular Permeability via Junction Adhesion Molecule a Tyrosine Phosphorylation and Tight Junction Disruption

Rima Chattopadhyay, PhD, Venkatesh Kundamani-Sridharan, PhD, Alexander Tinnikov, PhD, Elena Dyukova, PhD, Nikhlesh K Singh, PhD, Sivareddy Kotla, PhD, Gadiparthi N Rao, PhD
Journal: Blood
Blood (2014) 124 (21): 5000.
https://doi.org/10.1182/blood.V124.21.5000.5000
Published: 2014
Journal Articles

Metabolic Profiling in Sickle Cell Disease

Borys Hrinczenko, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 4837.
https://doi.org/10.1182/blood.V118.21.4837.4837
Published: 2011
Journal Articles

Differential Effects of Lovastatin and Allopurinol Therapy in a Murine Model of Sickle Cell Disease.

Kirkwood A. Pritchard, Jr., Terri L. Besch, Jingli Wang, Hao Xu, Deron W. Jones, Thomas D. Foster, Sandra L. Holzhauer, Keith T. Oldham, Nancy J. Wandersee, Cheryl A. Hillery
Journal: Blood
Blood (2005) 106 (11): 2325.
https://doi.org/10.1182/blood.V106.11.2325.2325
Published: 2005
Journal Articles

Low-Dose Recombinante Urate Oxidase (Rasburicase) Is Effective in Treating Hyperuricemia in Patients with Hematologic Malignancies.

S. Trifilio, A. Evens, L. Gordon, S. Singhal, M. Tallman, J. Mehta
Journal: Blood
Blood (2005) 106 (11): 3123.
https://doi.org/10.1182/blood.V106.11.3123.3123
Published: 2005
Journal Articles

Superoxide Inhibits ADAMTS-13 Activity and Regulates Sickle Cell Adhesion.

Prasenjit Guchhait, PhD, Miguel A. Cruz, PhD, Jing-Fei Dong, MD, PhD, José A. López, MD
Journal: Blood
Blood (2005) 106 (11): 2342.
https://doi.org/10.1182/blood.V106.11.2342.2342
Published: 2005
Journal Articles

Nitric Oxide Scavenging, Abnormal Vasoregulation and Oxidative Damage in sph/sph Mice with Severe Hereditary Spherocytosis: Possible Consequences of Red Blood Cell Hemolysis.

Anne C. Schraufnagel, Barb Piknova, PhD, Kirkwood A. Pritchard, Jr., PhD, Neil Hogg, PhD, Nancy J. Wandersee, PhD
Journal: Blood
Blood (2005) 106 (11): 1660.
https://doi.org/10.1182/blood.V106.11.1660.1660
Published: 2005
Journal Articles

Low-Dose Recombinante Urate Oxidase (Rasburicase) Is Effective in Hyperuricemia.

S. Trifilio, M. Tallman, S. Singhal, L. Gordon, A. Evens, J. Mehta
Journal: Blood
Blood (2004) 104 (11): 3312.
https://doi.org/10.1182/blood.V104.11.3312.3312
Published: 2004
Journal Articles

Honokiol Overcomes Conventional Drug Resistance in Human Multiple Myeloma.

Kenji Ishitsuka, M.D., Ph.D, Teru Hideshima, M.D., Ph.D, Makoto Hamasaki, M.D., Ph.D, Raje Noopur, M.D., Ph.D, Kumar Shaji, M.D., Ph.D, Hiromasa Hideshima, Norihiko Shiraishi, Ph.D, Paul Richardson, M.D., Ph.D, Nikhil C. Munshi, M.D., Ph.D, Dharminder Chauhan, Ph.D, Jack Arbiser, M.D., Ph.D, Kenneth C. Anderson, M.D., Ph.D
Journal: Blood
Blood (2004) 104 (11): 1488.
https://doi.org/10.1182/blood.V104.11.1488.1488
Published: 2004
Journal Articles

Absorption of Hemoglobin Iron: The Role of Xanthine Oxidase in the Intestinal Heme-Splitting Reaction

R. BEN DAWSON, M.D., SHEILA RAFAL, M.D., LEWIS R. WEINTRAUB, B.S.
Journal: Blood
Blood (1970) 35 (1): 94–103.
https://doi.org/10.1182/blood.V35.1.94.94
Published: 1970