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Issue Archive

Volume 8, Issue 18
September 24 2024
Issue Cover

Table of Contents

INSIDE BLOOD ADVANCES

Thrombophilia testing: does practice follow guidelines?
Clinical Trials & Observations
Saskia Middeldorp,Alfonso Iorio
View Articletitled, Thrombophilia testing: does practice follow guidelines?
Addressing and overcoming disparities in GVHD
Hemant S. Murthy
View Articletitled, Addressing and overcoming disparities in GVHD
Defining infection risk of bispecific antibodies for myeloma
Sarah P. Hammond
View Articletitled, Defining infection risk of bispecific antibodies for myeloma

SYSTEMATIC REVIEW

The clinical picture of Castleman disease: a systematic review and meta-analysis
Christian Hoffmann,Eric Oksenhendler,Sarah Littler,Lisa Grant,Karan Kanhai,David C. Fajgenbaum
View Articletitled, The clinical picture of Castleman disease: a systematic review and meta-analysis
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

A phase 2 study of a longitudinal multidimensional rehabilitation program for allogeneic blood and marrow transplantation patients
Clinical Trials & Observations
Samantha Tam,Shabbir M. H. Alibhai,Dima Hassanieh,Rajat Kumar,Jonas Mattsson,Eshetu G. Atenafu,Lisa Avery,Lori J. Bernstein,Eugene Chang,David Langelier,Paty Lopez,Jennifer M. Jones
View Articletitled, A phase 2 study of a longitudinal multidimensional rehabilitation program for allogeneic blood and marrow transplantation patients
Supplemental data
Yttrium-90 anti-CD25 BEAM conditioning for autologous hematopoietic cell transplantation in Peripheral T-cell lymphoma
Clinical Trials & Observations
Jasmine Zain,Ni-Chun Tsai,Joycelynne Palmer,Jennifer Simpson,Vikram Adhikarla,James R. Bading,Paul Yazaki,Eileen P. Smith,Savita Dandapani,Joo Y. Song,Nicole A. Karras,Alex F. Herrera,Amandeep Salhotra,Auayporn P. Nademanee,Ryotaro Nakamura,D. Lynne Smith,David Yamauchi,Erasmus K. Poku,V. Eric Biglang-Awa,David Colcher,John E. Shively,Anna M. Wu,Stephen J. Forman,Jeffrey Wong,Sandra Thomas
View Articletitled, Yttrium-90 anti-CD25 BEAM conditioning for autologous hematopoietic cell transplantation in Peripheral T-cell lymphoma
Supplemental data
Hodgkin lymphoma involving the extra-axial CNS: an AHOD1331, PHL-C1, and PHL-C2 report from the COG and EuroNet-PHL
Clinical Trials & Observations
Reena Pabari,Kathleen McCarten,Jamie Flerlage,Hollie Lai,Christine Mauz-Körholz,Karin Dieckmann,Monica Palese,Sue Kaste,Sharon M. Castellino,Kara M. Kelly,Dietrich Stoevesandt,Lars Kurch
View Articletitled, Hodgkin lymphoma involving the extra-axial CNS: an AHOD1331, PHL-C1, and PHL-C2 report from the COG and EuroNet-PHL
Supplemental data
CHRONOS-4: phase 3 study of copanlisib plus rituximab-based immunochemotherapy in relapsed indolent B-cell lymphoma
Clinical Trials & Observations
Pier Luigi Zinzani,Huaqing Wang,Jifeng Feng,Tae Min Kim,Rong Tao,Huilai Zhang,Laura Fogliatto,Clara Maluquer Artigal,Muhit Özcan,Eduardo Yanez,Won Seog Kim,Dmitry Kirtbaya,Iryna Kriachok,Felipe Maciel,Hongwei Xue,Krimo Bouabdallah,Charles Phelps,Shalini Chaturvedi,Anke Weispfenning,Peter N. Morcos,Fatuma Odongo,Viktoriya Buvaylo,Barrett H. Childs,Martin Dreyling,Matthew Matasar,Paola Ghione
View Articletitled, CHRONOS-4: phase 3 study of copanlisib plus rituximab-based immunochemotherapy in relapsed indolent B-cell lymphoma
Supplemental data
More early bleeds associated with high baseline direct oral anticoagulant levels in atrial fibrillation: the MAS study
Clinical Trials & Observations
Gualtiero Palareti,Sophie Testa,Cristina Legnani,Claudia Dellanoce,Michela Cini,Oriana Paoletti,Antonio Ciampa,Emilia Antonucci,Daniela Poli,Rossella Morandini,Maurizio Tala,Paolo Chiarugi,Rita Carlotta Santoro,Angela Maria Iannone,Erica De Candia,Pasquale Pignatelli,Elena Maria Faioni,Antonio Chistolini,Maria del Pilar Esteban,Marco Marietta,Armando Tripodi,Alberto Tosetto,for the MAS Study group
View Articletitled, More early bleeds associated with high baseline direct oral anticoagulant levels in atrial fibrillation: the MAS study
Supplemental data

GENE THERAPY

Utilizing epigenetic regulators to improve HSC-based lentiviral gene therapy
Parisa Tajer,Emin Onur Karakaslar,Kirsten Canté-Barrett,Brigitta A. E. Naber,Sandra A. Vloemans,Marja C. J. A. van Eggermond,Marie-Louise van der Hoorn,Erik van den Akker,Karin Pike-Overzet,Frank J. T. Staal
View Articletitled, Utilizing epigenetic regulators to improve HSC-based lentiviral gene therapy
Supplemental data

HEALTH SERVICES AND OUTCOMES

Evaluating the impact of a year-long external mentorship pilot program in classical hematology
Zoya Qureshy,Pooja Nair,Sara K. Vesely,Allison A. King,Alfred I. Lee,Nathan T. Connell,Annette von Drygalski,Ida Wong-Sefidan,Martina C. Murphy,Ronak H. Mistry,Rebecca L. Zon,Erin G. Reid,Josel Fritz,Soo J. Park
View Articletitled, Evaluating the impact of a year-long external mentorship pilot program in classical hematology
Supplemental data
Racial, ethnic, and socioeconomic diversity and outcomes of patients with graft-versus-host disease: a CIBMTR analysis
Nosha Farhadfar,Nahid Rashid,Karen Chen,Jakob DeVos,Tao Wang,Karen Ballen,Amer Beitinjaneh,Vijaya Raj Bhatt,Betty K. Hamilton,Peiman Hematti,Shahinaz M. Gadalla,Scott R. Solomon,Najla El Jurdi,Catherine J. Lee,Margaret L. MacMillan,Hemalatha G. Rangarajan,Hélène Schoemans,Akshay Sharma,Stephen R. Spellman,John R. Wingard,Stephanie J. Lee
View Articletitled, Racial, ethnic, and socioeconomic diversity and outcomes of patients with graft-versus-host disease: a CIBMTR analysis
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Permissible HLA mismatches in 9/10 unrelated donor pediatric stem cell transplants using HLA-EMMA: an EBMT Inborn Errors Working Party study
Erik G. J. von Asmuth,Fleur Hiensch,Sebastiaan Heidt,Alexander B. Mohseny,Dave L. Roelen,Cynthia S. M. Kramer,Frans H. J. Claas,Michael H. Albert,Bénédicte Neven,Arjan C. Lankester,Adriaan A. van Beek
View Articletitled, Permissible HLA mismatches in 9/10 unrelated donor pediatric stem cell transplants using HLA-EMMA: an EBMT Inborn Errors Working Party study
Supplemental data

LYMPHOID NEOPLASIA

Outcomes of patients with R/R B-cell NHL and limited (<5 sites) pre-CART disease bridged with or without radiotherapy
Omran Saifi,William G. Breen,Scott C. Lester,William G. Rule,Bradley J. Stish,Allison Rosenthal,Javier Munoz,Yi Lin,Radhika Bansal,Matthew A. Hathcock,Patrick B. Johnston,Stephen M. Ansell,Jonas Paludo,Arushi Khurana,Jose C. Villasboas,Yucai Wang,Madiha Iqbal,Muhamad Alhaj Moustafa,Hemant S. Murthy,Ernesto Ayala,Mohamed A. Kharfan-Dabaja,Bradford S. Hoppe,Jennifer L. Peterson
View Articletitled, Outcomes of patients with R/R B-cell NHL and limited (&lt;5 sites) pre-CART disease bridged with or without radiotherapy

MYELOID NEOPLASIA

Intensive induction chemotherapy vs hypomethylating agents in combination with venetoclax in NPM1-mutant AML
Jan Philipp Bewersdorf,Shai Shimony,Rory M. Shallis,Yiwen Liu,Guillaume Berton,Eva J. Schaefer,Amer M. Zeidan,Aaron D. Goldberg,Eytan M. Stein,Guido Marcucci,Rebecca P. Bystrom,R. Coleman Lindsley,Evan C. Chen,Jorge Ramos Perez,Anthony Stein,Vinod Pullarkat,Ibrahim Aldoss,Daniel J. DeAngelo,Donna S. Neuberg,Richard M. Stone,Sylvain Garciaz,Brian Ball,Maximilian Stahl
View Articletitled, Intensive induction chemotherapy vs hypomethylating agents in combination with venetoclax in <em>NPM1</em>-mutant AML
Supplemental data

PLASMA CELL DISORDERS

Anti-BCMA–engineered exosomes for bortezomib-targeted delivery in multiple myeloma
Shushu Yuan,Qi Li,Chuan He,Mengli Bing,Xinyun Zhang,Hao Xu,Zhiming Wang,Meifang Zhao,Yucheng Zhang,Yali Chai,Bingzong Li,Wenzhuo Zhuang
View Articletitled, Anti-BCMA–engineered exosomes for bortezomib-targeted delivery in multiple myeloma
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Intracranial aneurysms in sickle cell disease are associated with hemodynamic stress and anemia
Yan Wang,Jared S. Garland,Slim Fellah,Martin N. Reis,Matthew S. Parsons,Kristin P. Guilliams,Melanie E. Fields,Amy E. Mirro,Josiah B. Lewis,Chunwei Ying,Rachel A. Cohen,Monica L. Hulbert,Allison A. King,Yasheng Chen,Jin-Moo Lee,Hongyu An,Andria L. Ford
View Articletitled, Intracranial aneurysms in sickle cell disease are associated with hemodynamic stress and anemia
Supplemental data

THROMBOSIS AND HEMOSTASIS

LMWH prevents thromboinflammation in the placenta via HBEGF-AKT signaling
Kunal Kumar Singh,Anubhuti Gupta,Désirée Forstner,Jacqueline Guettler,Mirjam Susanne Ahrens,Akshay Prakasan Sheeja,Sameen Fatima,Saikal Shamkeeva,Massimiliano Lia,Anne Dathan-Stumpf,Nikola Hoffmann,Khurrum Shahzad,Holger Stepan,Martin Gauster,Berend Isermann,Shrey Kohli
View Articletitled, LMWH prevents thromboinflammation in the placenta via HBEGF-AKT signaling
Supplemental data
Venous thromboembolism characteristics and outcomes among RIETE patients tested and untested for inherited thrombophilia
Omri Cohen,Liat Waldman Radinsky,Gili Kenet,Isabelle Mahé,Giovanni Barillari,Silvia Soler,Patricia Sigüenza,María Del Valle Morales,Paula Villares,Manuel Monreal,the RIETE Investigators
View Articletitled, Venous thromboembolism characteristics and outcomes among RIETE patients tested and untested for inherited thrombophilia

TRANSPLANTATION

Unrelated donor transplantation with posttransplant cyclophosphamide vs ATG for myelodysplastic neoplasms
Yves Chalandon,Diderik-Jan Eikema,Ivan Moiseev,Fabio Ciceri,Linda Koster,Jan Vydra,Jakob Passweg,Montserrat Rovira,Tulay Ozcelik,Tobias Gedde-Dahl,Nicolaus Kröger,Victoria Potter,Ibrahim Yakoub-Agha,Alessandro Rambaldi,Maija Itälä-Remes,Alina Tanase,Francesco Onida,Carmelo Gurnari,Christof Scheid,Joanna Drozd-Sokolowska,Kavita Raj,Donal P. McLornan,Marie Robin
View Articletitled, Unrelated donor transplantation with posttransplant cyclophosphamide vs ATG for myelodysplastic neoplasms
Supplemental data
CD70 identifies alloreactive T cells and represents a potential target for prevention and treatment of acute GVHD
Kriti Verma,Wayne Croft,Sandra Margielewska-Davies,Hayden Pearce,Christine Stephens,Diana Diaconescu,Sarah Bevington,Charles Craddock,Rasoul Amel-Kashipaz,Jianmin Zuo,Francesca A. M. Kinsella,Paul Moss
View Articletitled, CD70 identifies alloreactive T cells and represents a potential target for prevention and treatment of acute GVHD
Supplemental data

RESEARCH LETTERS

Long-term clinical outcomes of prophylaxis with an rFVIIIFc or rFIXFc in adults aged ≥50 years with hemophilia A or B
Clinical Trials & Observations
Doris Quon,Shannon Jackson,María Teresa Alvarez-Román,Umer Khan,Sandra Casiano,Margaret V. Ragni,Savita Rangarajan
View Articletitled, Long-term clinical outcomes of prophylaxis with an rFVIIIFc or rFIXFc in adults aged ≥50 years with hemophilia A or B
Supplemental data
Anticoagulation for the treatment of immune checkpoint inhibitor–associated venous thromboembolism
Cho-Han Chiang,Soravis Osataphan,Yu-Cheng Chang,Kuan-Yu Chi,Cho-Hung Chiang,Yu Chang,Rushad Patell
View Articletitled, Anticoagulation for the treatment of immune checkpoint inhibitor–associated venous thromboembolism
Supplemental data
Molecular and clinical characterization of ETNK1-mutated myeloid neoplasms: the Mayo Clinic experience
Steven Tessier,Rong He,Patricia Greipp,David Viswanatha,Kurt Bessonen,Terra Lasho,James Foran,Cecilia Arana-Yi,Naseema Gangat,Ayalew Tefferi,Mithun Shah,Hassan Alkhateeb,Shujun Liu,Animesh Pardanani,Mrinal Patnaik,Aref Al-Kali
View Articletitled, Molecular and clinical characterization of <em>ETNK1</em>-mutated myeloid neoplasms: the Mayo Clinic experience
Supplemental data
Proposal for harmonizing the reporting of infections during treatment with bispecific antibodies in multiple myeloma
Clinical Trials & Observations
Heinz Ludwig,Nikhil C. Munshi,Evangelos Terpos,Ilvy Schweitzer,Noopur Raje,Philippe Moreau,Ajay Nooka
View Articletitled, Proposal for harmonizing the reporting of infections during treatment with bispecific antibodies in multiple myeloma
Supplemental data

ERRATUM

Tin E, Lee JB, Khatri I, et al. Double-negative T cells utilize a TNFα–JAK1–ICAM-1 cytotoxic axis against acute myeloid leukemia. Blood Adv. 2024;8(12):3013-3026.
View Articletitled, Tin E, Lee JB, Khatri I, et al. Double-negative T cells utilize a TNFα–JAK1–ICAM-1 cytotoxic axis against acute myeloid leukemia. <em>Blood Adv.</em> 2024;8(12):3013-3026.
  • Cover Image

    Cover Image

    issue cover

    Schematic representation showing the protective effects of low molecular weight heparins in preventing placental thromboinflammation. See the article by Singh et al.

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