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David Lillicrap
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Journal Articles

Novel cysteine substitution p.(Cys1084Tyr) causes variable expressivity of qualitative and quantitative VWF defects

Orla Rawley, Laura L. Swystun, Christine Brown, Kate Nesbitt, Margaret Rand, Taneya Hossain, Robert Klaassen, Paula D. James, Manuel D. Carcao, David Lillicrap
Journal: Blood Advances
Blood Adv (2022) 6 (9): 2908–2919.
https://doi.org/10.1182/bloodadvances.2021005928
Published: 2022
Includes: Supplemental data
Journal Articles

Multifaceted pathomolecular mechanism of a VWF large deletion involved in the pathogenesis of severe VWD

Hamideh Yadegari, Muhammad Ahmer Jamil, Jens Müller, Natascha Marquardt, Orla Rawley, Ulrich Budde, Osman El-Maarri, David Lillicrap, Johannes Oldenburg
Journal: Blood Advances
Blood Adv (2022) 6 (3): 1038–1053.
https://doi.org/10.1182/bloodadvances.2021005895
Published: 2022
Includes: Multimedia, Supplemental data
Journal Articles

Molecular coevolution of coagulation factor VIII and von Willebrand factor

Philip M. Zakas, Christopher W. Coyle, Anja Brehm, Marion Bayer, Barbara Solecka-Witulska, Caelan E. Radford, Christine Brown, Kate Nesbitt, Courtney Dwyer, Christoph Kannicht, H. Trent Spencer, Eric A. Gaucher, Christopher B. Doering, David Lillicrap
Journal: Blood Advances
Blood Adv (2021) 5 (3): 812–822.
https://doi.org/10.1182/bloodadvances.2020002971
Published: 2021
Includes: Supplemental data
Journal Articles

Gut dysbiosis modulates the immune response to factor VIII in murine hemophilia A

Julie Tarrant, Matthew Cormier, Kate Nesbitt, Courtney Dwyer, Christine Hough, David Lillicrap
Journal: Blood Advances
Blood Adv (2020) 4 (12): 2644–2655.
https://doi.org/10.1182/bloodadvances.2019001144
Published: 2020
Includes: Supplemental data
Journal Articles

The common VWF single nucleotide variants c.2365A>G and c.2385T>C modify VWF biosynthesis and clearance

Ahmad H. Mufti, Kenichi Ogiwara, Laura L. Swystun, Jeroen C. J. Eikenboom, Ulrich Budde, Wilma M. Hopman, Christer Halldén, Jenny Goudemand, Ian R. Peake, Anne C. Goodeve, David Lillicrap, Daniel J. Hampshire
Journal: Blood Advances
Blood Adv (2018) 2 (13): 1585–1594.
https://doi.org/10.1182/bloodadvances.2017011643
Published: 2018
Includes: Supplemental data