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Helena C. Brown
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Journal Articles

Selective Btk inhibition by PRN1008/PRN473 blocks human CLEC-2, and PRN473 reduces venous thrombosis formation in mice

Christopher W. Smith, Joana Campos, Helena C. Brown, Natalie J. Jooss, Vanesa-Sindi Ivanova, Maan Harbi, Lourdes Garcia-Quintanilla, Sian Jossi, Marisol Perez-Toledo, Kieran Rookes, Alexander Brill, Lindsay N. Theodore, Tim Owens, Jacob LaStant, Matthew C. Foulke, Shin Mukai, Michelle Francesco, Michael Storek, Alexandra Hicks, Claire Langrish, Philip A. Nunn, Adam F. Cunningham, Abhi Chauhan, Mark R. Thomas, Steve P. Watson, Phillip L. R. Nicolson
Journal: Blood Advances
Blood Adv (2024) 8 (21): 5557–5570.
https://doi.org/10.1182/bloodadvances.2024012713
Published: 2024
Includes: Supplemental data
Journal Articles

Antibody-mediated depletion of human CLEC-2 in a novel humanized mouse model

Helena C. Brown, Sarah Beck, Stefano Navarro, Ying Di, Eva M. Soriano Jerez, Jana Kaczmarzyk, Steven G. Thomas, Valbona Mirakaj, Steve P. Watson, Bernhard Nieswandt, David Stegner
Journal: Blood Advances
Blood Adv (2023) 7 (6): 997–1000.
https://doi.org/10.1182/bloodadvances.2021006463
Published: 2023
Includes: Supplemental data