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Koichi Akashi
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Journal Articles

Thrombospondin-1 is an endogenous substrate of cereblon responsible for immunomodulatory drug–induced thromboembolism

Kiwamu Hatakeyama, Yoshikane Kikushige, Daisuke Ishihara, Shunsuke Yamamoto, Gentaro Kawano, Taro Tochigi, Toshihiro Miyamoto, Teppei Sakoda, Andy Christoforou, Yuya Kunisaki, Mitsuhiro Fukata, Koji Kato, Takumi Ito, Hiroshi Handa, Koichi Akashi
Journal: Blood Advances
Blood Adv (2024) 8 (3): 785–796.
https://doi.org/10.1182/bloodadvances.2023010080
Published: 2024
Includes: Supplemental data
Journal Articles

Human acute leukemia uses branched-chain amino acid catabolism to maintain stemness through regulating PRC2 function

Yoshikane Kikushige, Toshihiro Miyamoto, Yu Kochi, Yuichiro Semba, Maki Ohishi, Hidetoshi Irifune, Kiwamu Hatakeyama, Yuya Kunisaki, Takeshi Sugio, Teppei Sakoda, Kohta Miyawaki, Koji Kato, Tomoyoshi Soga, Koichi Akashi
Journal: Blood Advances
Blood Adv (2023) 7 (14): 3592–3603.
https://doi.org/10.1182/bloodadvances.2022008242
Published: 2023
Includes: Supplemental data
Journal Articles

TIM-3 signaling hijacks the canonical Wnt/β-catenin pathway to maintain cancer stemness in acute myeloid leukemia

Teppei Sakoda, Yoshikane Kikushige, Toshihiro Miyamoto, Hidetoshi Irifune, Takuya Harada, Kiwamu Hatakeyama, Yuya Kunisaki, Koji Kato, Koichi Akashi
Journal: Blood Advances
Blood Adv (2023) 7 (10): 2053–2065.
https://doi.org/10.1182/bloodadvances.2022008405
Published: 2023
Includes: Supplemental data
Journal Articles

A germinal center–associated microenvironmental signature reflects malignant phenotype and outcome of DLBCL

Kohta Miyawaki, Koji Kato, Takeshi Sugio, Kensuke Sasaki, Hiroaki Miyoshi, Yuichiro Semba, Yoshikane Kikushige, Yasuo Mori, Yuya Kunisaki, Hiromi Iwasaki, Toshihiro Miyamoto, Frank C. Kuo, Jon C. Aster, Koichi Ohshima, Takahiro Maeda, Koichi Akashi
Journal: Blood Advances
Blood Adv (2022) 6 (7): 2388–2402.
https://doi.org/10.1182/bloodadvances.2021004618
Published: 2022
Includes: Supplemental data
Journal Articles

Microenvironmental immune cell signatures dictate clinical outcomes for PTCL-NOS

Takeshi Sugio, Kohta Miyawaki, Koji Kato, Kensuke Sasaki, Kyohei Yamada, Javeed Iqbal, Toshihiro Miyamoto, Koichi Ohshima, Takahiro Maeda, Hiroaki Miyoshi, Koichi Akashi
Journal: Blood Advances
Blood Adv (2018) 2 (17): 2242–2252.
https://doi.org/10.1182/bloodadvances.2018018754
Published: 2018
Includes: Supplemental data
Journal Articles

Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack

J. Luis Espinoza, Mahmoud I. Elbadry, Kazuhisa Chonabayashi, Yoshinori Yoshida, Takamasa Katagiri, Kenichi Harada, Noriharu Nakagawa, Yoshitaka Zaimoku, Tatsuya Imi, Hiroyuki Takamatsu, Tatsuhiko Ozawa, Hiroyuki Maruyama, Hassan A. Hassanein, Amal Khalifa A. Noreldin, Katsuto Takenaka, Koichi Akashi, Hiroshi Hamana, Hiroyuki Kishi, Yoshiki Akatsuka, Shinji Nakao
Journal: Blood Advances
Blood Adv (2018) 2 (4): 390–400.
https://doi.org/10.1182/bloodadvances.2017013342
Published: 2018
Includes: Supplemental data
Journal Articles

Twist1 regulates embryonic hematopoietic differentiation through binding to Myb and Gata2 promoter regions

Kasem Kulkeaw, Tomoko Inoue, Tadafumi Iino, Kenzaburo Tani, Koichi Akashi, Nancy A. Speck, Yoichi Nakanishi, Daisuke Sugiyama
Journal: Blood Advances
Blood Adv (2017) 1 (20): 1672–1681.
https://doi.org/10.1182/bloodadvances.2017006056
Published: 2017
Includes: Supplemental data