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Lucy A. Godley
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Journal Articles

Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1 , GATA2 , and DDX41

Claire C. Homan, Michael W. Drazer, Kai Yu, David M. Lawrence, Jinghua Feng, Luis Arriola-Martinez, Matthew J. Pozsgai, Kelsey E. McNeely, Thuong Ha, Parvathy Venugopal, Peer Arts, Sarah L. King-Smith, Jesse Cheah, Mark Armstrong, Paul Wang, Csaba Bödör, Alan B. Cantor, Mario Cazzola, Erin Degelman, Courtney D. DiNardo, Nicolas Duployez, Remi Favier, Stefan Fröhling, Ana Rio-Machin, Jeffery M. Klco, Alwin Krämer, Mineo Kurokawa, Joanne Lee, Luca Malcovati, Neil V. Morgan, Georges Natsoulis, Carolyn Owen, Keyur P. Patel, Claude Preudhomme, Hana Raslova, Hugh Rienhoff, Tim Ripperger, Rachael Schulte, Kiran Tawana, Elvira Velloso, Benedict Yan, Erika Kim, Raman Sood, Amy P. Hsu, Steven M. Holland, Kerry Phillips, Nicola K. Poplawski, Milena Babic, Andrew H. Wei, Cecily Forsyth, Helen Mar Fan, Ian D. Lewis, Julian Cooney, Rachel Susman, Lucy C. Fox, Piers Blombery, Deepak Singhal, Devendra Hiwase, Belinda Phipson, Andreas W. Schreiber, Christopher N. Hahn, Hamish S. Scott, Paul Liu, Lucy A. Godley, Anna L. Brown
Journal: Blood Advances
Blood Adv (2023) 7 (20): 6092–6107.
https://doi.org/10.1182/bloodadvances.2023010045
Published: 2023
Includes: Supplemental data
Journal Articles

Paired bone marrow and peripheral blood samples demonstrate lack of widespread dissemination of some CH clones

Clinical Trials & Observations
Afaf E. G. Osman, Nuria Mencia-Trinchant, Caner Saygin, Luke Moma, Aelin Kim, Genevieve Housman, Matthew Pozsgai, Eti Sinha, Pooja Chandra, Duane C. Hassane, Andrea Sboner, Kishan Sangani, Nick DiNardi, Christopher Johnson, Sara S. Wallace, Bana Jabri, Hue Luu, Monica L. Guzman, Pinkal Desai, Lucy A. Godley
Journal: Blood Advances
Blood Adv (2023) 7 (9): 1910–1914.
https://doi.org/10.1182/bloodadvances.2022008521
Published: 2023
Includes: Supplemental data
Journal Articles

Allogeneic hematopoietic stem cell transplant outcomes in adults with inherited myeloid malignancies

Caner Saygin, Gregory Roloff, Christopher N. Hahn, Rakchha Chhetri, Saar Gill, Hany Elmariah, Chetasi Talati, Emma Nunley, Guimin Gao, Aelin Kim, Michael Bishop, Satyajit Kosuri, Soma Das, Deepak Singhal, Parvathy Venugopal, Claire C. Homan, Anna Brown, Hamish S. Scott, Devendra Hiwase, Lucy A. Godley
Journal: Blood Advances
Blood Adv (2023) 7 (4): 549–554.
https://doi.org/10.1182/bloodadvances.2022008172
Published: 2023
Includes: Supplemental data
Journal Articles

Revision of RUNX1 variant curation rules

Simone Feurstein, Xi Luo, Mancy Shah, Taylor Walker, Nikita Mehta, David Wu, Lucy A. Godley
Journal: Blood Advances
Blood Adv (2022) 6 (16): 4726–4730.
https://doi.org/10.1182/bloodadvances.2022008017
Published: 2022
Includes: Supplemental data
Journal Articles

Clonal hematopoiesis in patients with ANKRD26 or ETV6 germline mutations

Clinical Trials & Observations
Michael W. Drazer, Claire C. Homan, Kai Yu, Marcela Cavalcante de Andrade Silva, Kelsey E. McNeely, Matthew J. Pozsgai, Maria G. Acevedo-Mendez, Jeremy P. Segal, Peng Wang, Jinghua Feng, Sarah L. King-Smith, Erika Kim, Sophia Korotev, David M. Lawrence, Andreas W. Schreiber, Christopher N. Hahn, Hamish S. Scott, Raman Sood, NISC Comparative Sequencing Program, Elvira D. R. P. Velloso, Anna L. Brown, Paul P. Liu, Lucy A. Godley
Journal: Blood Advances
Blood Adv (2022) 6 (15): 4357–4359.
https://doi.org/10.1182/bloodadvances.2022007211
Published: 2022
Includes: Supplemental data
Journal Articles

Therapy-related myeloid neoplasms in 109 patients after radiation monotherapy

Clinical Trials & Observations
Anand Ashwin Patel, Alexandra E. Rojek, Michael W. Drazer, Howard Weiner, Lucy A. Godley, Michelle M. Le Beau, Richard A. Larson
Journal: Blood Advances
Blood Adv (2021) 5 (20): 4140–4148.
https://doi.org/10.1182/bloodadvances.2021004964
Published: 2021
Includes: Supplemental data
Journal Articles

Heterozygous germ line CSF3R variants as risk alleles for development of hematologic malignancies

Amy M. Trottier, Lawrence J. Druhan, Ira L. Kraft, Amanda Lance, Simone Feurstein, Maria Helgeson, Jeremy P. Segal, Soma Das, Belinda R. Avalos, Lucy A. Godley
Journal: Blood Advances
Blood Adv (2020) 4 (20): 5269–5284.
https://doi.org/10.1182/bloodadvances.2020002013
Published: 2020
Includes: Supplemental data
Journal Articles

Telomere biology disorder prevalence and phenotypes in adults with familial hematologic and/or pulmonary presentations

Clinical Trials & Observations
Simone Feurstein, Ayodeji Adegunsoye, Danijela Mojsilovic, Rekha Vij, Allison H. West DePersia, Padma Sheila Rajagopal, Afaf Osman, Robert H. Collins, Raymond H. Kim, Steven D. Gore, Peter Greenberg, Lucy A. Godley, Zejuan Li, Daniela del Gaudio, Hari Prasanna Subramanian, Soma Das, Tom Walsh, Suleyman Gulsuner, Jeremy P. Segal, Aliya N. Husain, Sandeep Gurbuxani, Mary-Claire King, Mary E. Strek, Jane E. Churpek
Journal: Blood Advances
Blood Adv (2020) 4 (19): 4873–4886.
https://doi.org/10.1182/bloodadvances.2020001721
Published: 2020
Includes: Supplemental data
Journal Articles

HIF-1 directly induces TET3 expression to enhance 5-hmC density and induce erythroid gene expression in hypoxia

John Z. Cao, Hui Liu, Amittha Wickrema, Lucy A. Godley
Journal: Blood Advances
Blood Adv (2020) 4 (13): 3053–3062.
https://doi.org/10.1182/bloodadvances.2020001535
Published: 2020
Includes: Supplemental data
Journal Articles

RUNX1 -mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML

Anna L. Brown, Peer Arts, Catherine L. Carmichael, Milena Babic, Julia Dobbins, Chan-Eng Chong, Andreas W. Schreiber, Jinghua Feng, Kerry Phillips, Paul P. S. Wang, Thuong Ha, Claire C. Homan, Sarah L. King-Smith, Lesley Rawlings, Cassandra Vakulin, Andrew Dubowsky, Jessica Burdett, Sarah Moore, Grace McKavanagh, Denae Henry, Amanda Wells, Belinda Mercorella, Mario Nicola, Jeffrey Suttle, Ella Wilkins, Xiao-Chun Li, Joelle Michaud, Peter Brautigan, Ping Cannon, Meryl Altree, Louise Jaensch, Miriam Fine, Carolyn Butcher, Richard J. D’Andrea, Ian D. Lewis, Devendra K. Hiwase, Elli Papaemmanuil, Marshall S. Horwitz, Georges Natsoulis, Hugh Y. Rienhoff, Jr, Nigel Patton, Sally Mapp, Rachel Susman, Susan Morgan, Julian Cooney, Mark Currie, Uday Popat, Tilmann Bochtler, Shai Izraeli, Kenneth Bradstock, Lucy A. Godley, Alwin Krämer, Stefan Fröhling, Andrew H. Wei, Cecily Forsyth, Helen Mar Fan, Nicola K. Poplawski, Christopher N. Hahn, Hamish S. Scott
Journal: Blood Advances
Blood Adv (2020) 4 (6): 1131–1144.
https://doi.org/10.1182/bloodadvances.2019000901
Published: 2020
Includes: Supplemental data
Journal Articles

A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia

Clinical Trials & Observations
Kirk E. Cahill, Yasmin H. Karimi, Theodore G. Karrison, Nitin Jain, Margaret Green, Howard Weiner, Noreen Fulton, Sabah Kadri, Lucy A. Godley, Andrew S. Artz, Hongtao Liu, Michael J. Thirman, Michelle M. Le Beau, Megan E. McNerney, Jeremy Segal, Richard A. Larson, Wendy Stock, Olatoyosi Odenike
Journal: Blood Advances
Blood Adv (2020) 4 (4): 599–606.
https://doi.org/10.1182/bloodadvances.2019000795
Published: 2020
Includes: Supplemental data
Journal Articles

ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants

Xi Luo, Simone Feurstein, Shruthi Mohan, Christopher C. Porter, Sarah A. Jackson, Sioban Keel, Michael Chicka, Anna L. Brown, Chimene Kesserwan, Anupriya Agarwal, Minjie Luo, Zejuan Li, Justyne E. Ross, Panagiotis Baliakas, Daniel Pineda-Alvarez, Courtney D. DiNardo, Alison A. Bertuch, Nikita Mehta, Tom Vulliamy, Ying Wang, Kim E. Nichols, Luca Malcovati, Michael F. Walsh, Lesley H. Rawlings, Shannon K. McWeeney, Jean Soulier, Anna Raimbault, Mark J. Routbort, Liying Zhang, Gabriella Ryan, Nancy A. Speck, Sharon E. Plon, David Wu, Lucy A. Godley
Journal: Blood Advances
Blood Adv (2019) 3 (20): 2962–2979.
https://doi.org/10.1182/bloodadvances.2019000644
Published: 2019
Includes: Supplemental data
Journal Articles

Inherited predisposition to myeloid malignancies

Lucy A. Godley
Journal: Blood Advances
Blood Adv (2019) 3 (17): 2688.
https://doi.org/10.1182/bloodadvances.2019000172
Published: 2019
Includes: Supplemental data
Journal Articles

Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies

Clinical Trials & Observations
Michael W. Drazer, Sabah Kadri, Madina Sukhanova, Sushant A. Patil, Allison H. West, Simone Feurstein, Dalein A. Calderon, Matthew F. Jones, Caroline M. Weipert, Christopher K. Daugherty, Adrián A. Ceballos-López, Gordana Raca, Mark W. Lingen, Zejuan Li, Jeremy P. Segal, Jane E. Churpek, Lucy A. Godley
Journal: Blood Advances
Blood Adv (2018) 2 (2): 146–150.
https://doi.org/10.1182/bloodadvances.2017013037
Published: 2018
Includes: Supplemental data