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Stephen Opat
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Journal Articles

Biomarker analysis of the ASPEN study comparing zanubrutinib with ibrutinib for patients with Waldenström macroglobulinemia

Clinical Trials & Observations
Constantine S. Tam, Stephen Opat, Shirley D'Sa, Wojciech Jurczak, Hui-Peng Lee, Gavin Cull, Roger G. Owen, Paula Marlton, Björn E. Wahlin, Ramón García-Sanz, Helen McCarthy, Stephen Mulligan, Alessandra Tedeschi, Jorge J. Castillo, Jarosław Czyż, Carlos Fernández De Larrea, David Belada, Edward Libby, Jeffrey Matous, Marina Motta, Tanya Siddiqi, Monica Tani, Marek Trněný, Monique C. Minnema, Christian Buske, Véronique Leblond, Steven P. Treon, Judith Trotman, Binghao Wu, Yiling Yu, Zhirong Shen, Wai Y. Chan, Jingjing Schneider, Heather Allewelt, Aileen Cohen, Meletios A. Dimopoulos
Journal: Blood Advances
Blood Adv (2024) 8 (7): 1639–1650.
https://doi.org/10.1182/bloodadvances.2023010906
Published: 2024
Includes: Supplemental data
Journal Articles

Safety and efficacy of zanubrutinib in relapsed/refractory marginal zone lymphoma: final analysis of the MAGNOLIA study

Clinical Trials & Observations
Stephen Opat, Alessandra Tedeschi, Bei Hu, Kim M. Linton, Pamela McKay, Sophie Leitch, Morton Coleman, Pier Luigi Zinzani, Jie Jin, Mingyuan Sun, Magdalena Sobieraj-Teague, Peter Browett, Xiaoyan Ke, Catherine Thieblemont, Kirit Ardeshna, Fontanet Bijou, Patricia Walker, Eliza A. Hawkes, Shir-Jing Ho, Keshu Zhou, Zhiyu Liang, Jianfeng Xu, Chris Tankersley, Richard Delarue, Melannie Co, Judith Trotman
Journal: Blood Advances
Blood Adv (2023) 7 (22): 6801–6811.
https://doi.org/10.1182/bloodadvances.2023010668
Published: 2023
Includes: Supplemental data
Journal Articles

Zanubrutinib for the treatment of relapsed/refractory hairy cell leukemia

Clinical Trials & Observations
Constantine S. Tam, Judith Trotman, Stephen Opat, Jennifer C. Stern, Heather Allewelt, Kunthel By, William Novotny, Jane Huang, Alessandra Tedeschi
Journal: Blood Advances
Blood Adv (2023) 7 (12): 2884–2887.
https://doi.org/10.1182/bloodadvances.2022008990
Published: 2023
Includes: Supplemental data
Journal Articles

Zanubrutinib monotherapy in relapsed/refractory indolent non-Hodgkin lymphoma

Clinical Trials & Observations
Tycel Phillips, Henry Chan, Constantine S. Tam, Alessandra Tedeschi, Patrick Johnston, Sung Yong Oh, Stephen Opat, Hyeon-Seok Eom, Heather Allewelt, Jennifer C. Stern, Ziwen Tan, William Novotny, Jane Huang, Judith Trotman
Journal: Blood Advances
Blood Adv (2022) 6 (11): 3472–3479.
https://doi.org/10.1182/bloodadvances.2021006083
Published: 2022
Includes: Supplemental data
Journal Articles

Risk profiling of patients with relapsed/refractory diffuse large B-cell lymphoma by measuring circulating tumor DNA

Clinical Trials & Observations
Alex F. Herrera, Samuel Tracy, Brandon Croft, Stephen Opat, Jill Ray, Alex F. Lovejoy, Lisa Musick, Joseph N. Paulson, Laurie H. Sehn, Yanwen Jiang
Journal: Blood Advances
Blood Adv (2022) 6 (6): 1651–1660.
https://doi.org/10.1182/bloodadvances.2021006415
Published: 2022
Includes: Supplemental data
Journal Articles

Pooled safety analysis of zanubrutinib monotherapy in patients with B-cell malignancies

Clinical Trials & Observations
Constantine S. Tam, Meletios Dimopoulos, Ramon Garcia-Sanz, Judith Trotman, Stephen Opat, Andrew W. Roberts, Roger Owen, Yuqin Song, Wei Xu, Jun Zhu, Jianyong Li, Lugui Qiu, Shirley D’Sa, Wojciech Jurczak, Gavin Cull, Paula Marlton, David Gottlieb, Javier Munoz, Tycel Phillips, Chenmu Du, Meng Ji, Lei Zhou, Haiyi Guo, Hongjie Zhu, Wai Y. Chan, Aileen Cohen, William Novotny, Jane Huang, Alessandra Tedeschi
Journal: Blood Advances
Blood Adv (2022) 6 (4): 1296–1308.
https://doi.org/10.1182/bloodadvances.2021005621
Published: 2022
Includes: Supplemental data
Journal Articles

Polatuzumab vedotin plus bendamustine and rituximab in relapsed/refractory DLBCL: survival update and new extension cohort data

Clinical Trials & Observations
Laurie H. Sehn, Mark Hertzberg, Stephen Opat, Alex F. Herrera, Sarit Assouline, Christopher R. Flowers, Tae Min Kim, Andrew McMillan, Muhit Ozcan, Violaine Safar, Gilles Salles, Grace Ku, Jamie Hirata, Yi Meng Chang, Lisa Musick, Matthew J. Matasar
Journal: Blood Advances
Blood Adv (2022) 6 (2): 533–543.
https://doi.org/10.1182/bloodadvances.2021005794
Published: 2022
Includes: Supplemental data
Journal Articles

Zanubrutinib for the treatment of relapsed or refractory mantle cell lymphoma

Clinical Trials & Observations
Constantine S. Tam, Stephen Opat, David Simpson, Gavin Cull, Javier Munoz, Tycel J. Phillips, Won Seog Kim, Simon Rule, Siminder Kaur Atwal, Rachel Wei, William Novotny, Jane Huang, Michael Wang, Judith Trotman
Journal: Blood Advances
Blood Adv (2021) 5 (12): 2577–2585.
https://doi.org/10.1182/bloodadvances.2020004074
Published: 2021
Includes: Supplemental data
Journal Articles

Zanubrutinib for the treatment of MYD88 wild-type Waldenström macroglobulinemia: a substudy of the phase 3 ASPEN trial

Clinical Trials & Observations
Meletios Dimopoulos, Ramon Garcia Sanz, Hui-Peng Lee, Marek Trneny, Marzia Varettoni, Stephen Opat, Shirley D'Sa, Roger G. Owen, Gavin Cull, Stephen Mulligan, Jaroslaw Czyz, Jorge J. Castillo, Marina Motta, Tanya Siddiqi, Mercedes Gironella Mesa, Miquel Granell Gorrochategui, Dipti Talaulikar, Pier Luigi Zinzani, Elham Askari, Sebastian Grosicki, Albert Oriol, Simon Rule, Janusz Kloczko, Alessandra Tedeschi, Christian Buske, Veronique Leblond, Judith Trotman, Wai Y. Chan, Jan Michel, Jingjing Schneider, Ziwen Tan, Aileen Cohen, Jane Huang, Constantine S. Tam
Journal: Blood Advances
Blood Adv (2020) 4 (23): 6009–6018.
https://doi.org/10.1182/bloodadvances.2020003010
Published: 2020
Includes: Supplemental data