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Journal Articles

Polyphosphate-induced thrombosis in mice is factor XII dependent and is attenuated by histidine-rich glycoprotein

Rida A. Malik, Ji Zhou, James C. Fredenburgh, Tammy K. Truong, Jeff R. Crosby, Alexey S. Revenko, Jeffrey I. Weitz

Blood Adv (2021) 5 (18): 3540–3551.

https://doi.org/10.1182/bloodadvances.2021004567

Published: 2021

Includes: Supplemental data

Journal Articles

High fibrinogen γ′ levels in patient plasma increase clot formation at arterial and venous shear

Fraser L. Macrae, Frauke Swieringa, Johan W. M. Heemskerk, Robert A. S. Ariëns

Blood Adv (2021) 5 (17): 3468–3477.

https://doi.org/10.1182/bloodadvances.2020003346

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Inflammasome activation promotes venous thrombosis through pyroptosis

Yan Zhang, Jian Cui, Guoying Zhang, Congqing Wu, Ahmed Abdel-Latif, Susan S. Smyth, Toshihiko Shiroishi, Nigel Mackman, Yinan Wei, Min Tao, Zhenyu Li

Blood Adv (2021) 5 (12): 2619–2623.

https://doi.org/10.1182/bloodadvances.2020003041

Published: 2021

Includes: Supplemental data

Journal Articles

Dominant role of αIIbβ3 in platelet interactions with cross-linked fibrin fragment D-dimer

Lorena Buitrago, Hina Zafar, Yixiao Zhang, Jihong Li, Thomas Walz, Barry S. Coller

Blood Adv (2020) 4 (13): 2939–2949.

https://doi.org/10.1182/bloodadvances.2020001545

Published: 2020

Journal Articles

Modulating the rate of fibrin formation and clot structure attenuates microvascular thrombosis in systemic inflammation

Christian Valladolid, Marina Martinez-Vargas, Nitin Sekhar, Fong Lam, Cameron Brown, Timothy Palzkill, Alexander Tischer, Mathew Auton, K. Vinod Vijayan, Rolando E. Rumbaut, Trung C. Nguyen, Miguel A. Cruz

Blood Adv (2020) 4 (7): 1340–1349.

https://doi.org/10.1182/bloodadvances.2020001500

Published: 2020

Includes: Supplemental data

Journal Articles

A murine photothrombotic stroke model with an increased fibrin content and improved responses to tPA-lytic treatment

Yu-Yo Sun, Yi-Min Kuo, Hong-Ru Chen, Jonah C. Short-Miller, Marchelle R. Smucker, Chia-Yi Kuan

Blood Adv (2020) 4 (7): 1222–1231.

https://doi.org/10.1182/bloodadvances.2019000782

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Tranexamic acid modulates the immune response and reduces postsurgical infection rates

Dominik F. Draxler, Kah Yep, Gryselda Hanafi, Anoushka Winton, Maria Daglas, Heidi Ho, Maithili Sashindranath, Lisa M. Wutzlhofer, Andrew Forbes, Isaac Goncalves, Huyen A. Tran, Sophia Wallace, Magdalena Plebanski, Paul S. Myles, Robert L. Medcalf

Blood Adv (2019) 3 (10): 1598–1609.

https://doi.org/10.1182/bloodadvances.2019000092

Published: 2019

Includes: Supplemental data

Journal Articles

Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice

Rikke Stagaard, Carsten Dan Ley, Kasper Almholt, Lisbeth Høier Olsen, Tom Knudsen, Matthew J. Flick

Blood Adv (2018) 2 (22): 3126–3136.

https://doi.org/10.1182/bloodadvances.2018024851

Published: 2018

Journal Articles

Platelet CD36 signaling through ERK5 promotes caspase-dependent procoagulant activity and fibrin deposition in vivo

Moua Yang, Andaleb Kholmukhamedov, Marie L. Schulte, Brian C. Cooley, Na’il O. Scoggins, Jeremy P. Wood, Scott J. Cameron, Craig N. Morrell, Shawn M. Jobe, Roy L. Silverstein

Blood Adv (2018) 2 (21): 2848–2861.

https://doi.org/10.1182/bloodadvances.2018025411

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

Platelet heterogeneity in activation-induced glycoprotein shedding: functional effects

Constance C. F. M. J. Baaten, Frauke Swieringa, Tomasz Misztal, Tom G. Mastenbroek, Marion A. H. Feijge, Paul E. Bock, Marjo M. P. C. Donners, Peter W. Collins, Renhao Li, Paola E. J. van der Meijden, Johan W. M. Heemskerk

Blood Adv (2018) 2 (18): 2320–2331.

https://doi.org/10.1182/bloodadvances.2017011544

Published: 2018

Includes: Supplemental data

Journal Articles

Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors

Manu T. Kalathottukaren, A. Louise Creagh, Srinivas Abbina, Genmin Lu, Mark J. Karbarz, Anjali Pandey, Pamela B. Conley, Jayachandran N. Kizhakkedathu, Charles Haynes

Blood Adv (2018) 2 (16): 2104–2114.

https://doi.org/10.1182/bloodadvances.2016003616

Published: 2018

Includes: Supplemental data

Journal Articles

A function-blocking PAR4 antibody is markedly antithrombotic in the face of a hyperreactive PAR4 variant

Shauna L. French, Claudia Thalmann, Paul F. Bray, Lynn E. Macdonald, Andrew J. Murphy, Mark W. Sleeman, Justin R. Hamilton

Blood Adv (2018) 2 (11): 1283–1293.

https://doi.org/10.1182/bloodadvances.2017015552

Published: 2018

Includes: Supplemental data

Journal Articles

Complement C5 but not C3 is expendable for tissue factor activation by cofactor-independent antiphospholipid antibodies

Nadine Müller-Calleja, Svenja Ritter, Anne Hollerbach, Tanja Falter, Karl J. Lackner, Wolfram Ruf

Blood Adv (2018) 2 (9): 979–986.

https://doi.org/10.1182/bloodadvances.2018017095

Published: 2018

Journal Articles

Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI

Blood Adv (2018) 2 (3): 240–251.

https://doi.org/10.1182/bloodadvances.2017011171

Published: 2018

Includes: Supplemental data

Journal Articles

Biocompatible coupling of therapeutic fusion proteins to human erythrocytes

Carlos H. Villa, Daniel C. Pan, Ian H. Johnston, Colin F. Greineder, Landis R. Walsh, Elizabeth D. Hood, Douglas B. Cines, Mortimer Poncz, Don L. Siegel, Vladimir R. Muzykantov

Blood Adv (2018) 2 (3): 165–176.

https://doi.org/10.1182/bloodadvances.2017011734

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

Factor XIII in plasma, but not in platelets, mediates red blood cell retention in clots and venous thrombus size in mice

Sravya Kattula, James R. Byrnes, Sara M. Martin, Lori A. Holle, Brian C. Cooley, Matthew J. Flick, Alisa S. Wolberg

Blood Adv (2018) 2 (1): 25–35.

https://doi.org/10.1182/bloodadvances.2017011890

Published: 2018

Includes: Supplemental data

Journal Articles

Fibrin and D-dimer bind to monomeric GPVI

Marie-Blanche Onselaer, Alexander T. Hardy, Clare Wilson, Ximena Sanchez, Amir K. Babar, Jeanette L. C. Miller, Callum N. Watson, Stephanie K. Watson, Arkadiusz Bonna, Helen Philippou, Andrew B. Herr, Diego Mezzano, Robert A. S. Ariëns, Steve P. Watson

Blood Adv (2017) 1 (19): 1495–1504.

https://doi.org/10.1182/bloodadvances.2017007732

Published: 2017

Includes: Supplemental data

Journal Articles

ICAM-1–targeted thrombomodulin mitigates tissue factor–driven inflammatory thrombosis in a human endothelialized microfluidic model

Colin F. Greineder, Ian H. Johnston, Carlos H. Villa, Kandace Gollomp, Charles T. Esmon, Douglas B. Cines, Mortimer Poncz, Vladimir R. Muzykantov

Blood Adv (2017) 1 (18): 1452–1465.

https://doi.org/10.1182/bloodadvances.2017007229

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

Reduced prothrombinase inhibition by tissue factor pathway inhibitor contributes to the factor V Leiden hypercoagulable state

Jeremy P. Wood, Lisa M. Baumann Kreuziger, Paul E. R. Ellery, Susan A. Maroney, Alan E. Mast

Blood Adv (2017) 1 (6): 386–395.

https://doi.org/10.1182/bloodadvances.2016002295

Published: 2017

Includes: Supplemental data

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Polyphosphate-induced thrombosis in mice is factor XII dependent and is attenuated by histidine-rich glycoprotein

High fibrinogen γ′ levels in patient plasma increase clot formation at arterial and venous shear

Inflammasome activation promotes venous thrombosis through pyroptosis

Dominant role of αIIbβ3 in platelet interactions with cross-linked fibrin fragment D-dimer

Modulating the rate of fibrin formation and clot structure attenuates microvascular thrombosis in systemic inflammation

A murine photothrombotic stroke model with an increased fibrin content and improved responses to tPA-lytic treatment

Tranexamic acid modulates the immune response and reduces postsurgical infection rates

Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice

Platelet CD36 signaling through ERK5 promotes caspase-dependent procoagulant activity and fibrin deposition in vivo

Platelet heterogeneity in activation-induced glycoprotein shedding: functional effects

Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors

A function-blocking PAR4 antibody is markedly antithrombotic in the face of a hyperreactive PAR4 variant

Complement C5 but not C3 is expendable for tissue factor activation by cofactor-independent antiphospholipid antibodies

Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI

Biocompatible coupling of therapeutic fusion proteins to human erythrocytes

Factor XIII in plasma, but not in platelets, mediates red blood cell retention in clots and venous thrombus size in mice

Fibrin and D-dimer bind to monomeric GPVI

ICAM-1–targeted thrombomodulin mitigates tissue factor–driven inflammatory thrombosis in a human endothelialized microfluidic model

Reduced prothrombinase inhibition by tissue factor pathway inhibitor contributes to the factor V Leiden hypercoagulable state

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