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Journal Articles

Proteomic and bioinformatic profiling of neutrophils in CLL reveals functional defects that predispose to bacterial infections

Nirojah Subramaniam, Jenny Bottek, Stephanie Thiebes, Kristina Zec, Matthias Kudla, Camille Soun, Elena de Dios Panal, Julia K. Lill, Aaron Pfennig, Ralf Herrmann, Kirsten Bruderek, Sven Rahmann, Sven Brandau, Patricia Johansson, Hans Christian Reinhardt, Jan Dürig, Martina Seiffert, Thilo Bracht, Barbara Sitek, Daniel Robert Engel
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1259–1272.
https://doi.org/10.1182/bloodadvances.2020002949
Published: 2021
Includes: Supplemental data
Journal Articles

Loss of the exocyst complex component EXOC3 promotes hemostasis and accelerates arterial thrombosis

Tony G. Walsh, Yong Li, Christopher M. Williams, Elizabeth W. Aitken, Robert K. Andrews, Alastair W. Poole
Journal: Blood Advances
Blood Adv (2021) 5 (3): 674–686.
https://doi.org/10.1182/bloodadvances.2020002515
Published: 2021
Includes: Supplemental data
Journal Articles

Platelet α-granules are required for occlusive high-shear-rate thrombosis

Dongjune A. Kim, Katrina J. Ashworth, Jorge Di Paola, David N. Ku
Journal: Blood Advances
Blood Adv (2020) 4 (14): 3258–3267.
https://doi.org/10.1182/bloodadvances.2020002117
Published: 2020
Journal Articles

GRK6 regulates the hemostatic response to injury through its rate-limiting effects on GPCR signaling in platelets

Xi Chen, Shuchi Gupta, Matthew Cooper, Daniel DeHelian, Xuefei Zhao, Meghna U. Naik, Jeremy G. T. Wurtzel, Timothy J. Stalker, Lawrence E. Goldfinger, Jeffrey Benovic, Lawrence F. Brass, Steven E. McKenzie, Ulhas P. Naik, Peisong Ma
Journal: Blood Advances
Blood Adv (2020) 4 (1): 76–86.
https://doi.org/10.1182/bloodadvances.2019000467
Published: 2020
Includes: Supplemental data
Journal Articles

Platelet α-granules contribute to organ-specific pathologies in a mouse model of severe malaria

Thayer K. Darling, Michael P. Schenk, Chengjing C. Zhou, Franklin M. Maloba, Patrice N. Mimche, Jonathan M. Gibbins, Shawn M. Jobe, Tracey J. Lamb
Journal: Blood Advances
Blood Adv (2019) 4 (1): 1–8.
https://doi.org/10.1182/bloodadvances.2019000773
Published: 2019
Includes: Supplemental data
Journal Articles

Ether lipid metabolism by AADACL1 regulates platelet function and thrombosis

Stephen P. Holly, Nidhi Gera, Putianqi Wang, Alexander Wilson, Ziqiang Guan, Ling Lin, Brian Cooley, Hammodah R. Alfar, Ruchi G. Patil, Raymond Piatt, Tina M. Leisner, Wolfgang Bergmeier, Rinku Majumder, Leslie V. Parise
Journal: Blood Advances
Blood Adv (2019) 3 (22): 3818–3828.
https://doi.org/10.1182/bloodadvances.2018030767
Published: 2019
Includes: Supplemental data
Journal Articles

Megakaryocytes package contents into separate α-granules that are differentially distributed in platelets

Elisabeth M. Battinelli, Jonathan N. Thon, Ross Okazaki, Christian G. Peters, Prakrith Vijey, Adrian R. Wilkie, Leila J. Noetzli, Robert Flaumenhaft, Joseph E. Italiano, Jr
Journal: Blood Advances
Blood Adv (2019) 3 (20): 3092–3098.
https://doi.org/10.1182/bloodadvances.2018020834
Published: 2019
Includes: Multimedia, Supplemental data
Journal Articles

Mechanism of platelet α-granule biogenesis: study of cargo transport and the VPS33B-VPS16B complex in a model system

Andrea L. Ambrosio, Santiago M. Di Pietro
Journal: Blood Advances
Blood Adv (2019) 3 (17): 2617–2626.
https://doi.org/10.1182/bloodadvances.2018028969
Published: 2019
Includes: Supplemental data
Journal Articles

Combined deficiency of RAB32 and RAB38 in the mouse mimics Hermansky-Pudlak syndrome and critically impairs thrombosis

Alicia Aguilar, Josiane Weber, Julie Boscher, Monique Freund, Catherine Ziessel, Anita Eckly, Stéphanie Magnenat, Catherine Bourdon, Béatrice Hechler, Pierre H. Mangin, Christian Gachet, François Lanza, Catherine Léon
Journal: Blood Advances
Blood Adv (2019) 3 (15): 2368–2380.
https://doi.org/10.1182/bloodadvances.2019031286
Published: 2019
Includes: Supplemental data
Journal Articles

ELMO1 deficiency enhances platelet function

Akruti Patel, John Kostyak, Carol Dangelmaier, Rachit Badolia, Dheeraj Bhavanasi, Joseph E. Aslan, Salim Merali, Soochong Kim, Johannes A. Eble, Lawrence Goldfinger, Satya Kunapuli
Journal: Blood Advances
Blood Adv (2019) 3 (4): 575–587.
https://doi.org/10.1182/bloodadvances.2018016444
Published: 2019
Includes: Supplemental data
Journal Articles

Platelet-specific deletion of SNAP23 ablates granule secretion, substantially inhibiting arterial and venous thrombosis in mice

Christopher M. Williams, Yong Li, Edward Brown, Alastair W. Poole
Journal: Blood Advances
Blood Adv (2018) 2 (24): 3627–3636.
https://doi.org/10.1182/bloodadvances.2018023291
Published: 2018
Journal Articles

HoxA9 transforms murine myeloid cells by a feedback loop driving expression of key oncogenes and cell cycle control genes

Xiaoxia Zhong, Andreas Prinz, Julia Steger, Maria-Paz Garcia-Cuellar, Markus Radsak, Abderrazzak Bentaher, Robert K. Slany
Journal: Blood Advances
Blood Adv (2018) 2 (22): 3137–3148.
https://doi.org/10.1182/bloodadvances.2018025866
Published: 2018
Includes: Supplemental data
Journal Articles

SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets

Irina D. Pokrovskaya, Smita Joshi, Michael Tobin, Rohan Desai, Maria A. Aronova, Jeffrey A. Kamykowski, Guofeng Zhang, Sidney W. Whiteheart, Richard D. Leapman, Brian Storrie
Journal: Blood Advances
Blood Adv (2018) 2 (21): 2947–2958.
https://doi.org/10.1182/bloodadvances.2018019158
Published: 2018
Includes: Multimedia, Supplemental data
Journal Articles

Alterations in platelet secretion differentially affect thrombosis and hemostasis

Smita Joshi, Meenakshi Banerjee, Jinchao Zhang, Akhil Kesaraju, Irina D. Pokrovskaya, Brian Storrie, Sidney W. Whiteheart
Journal: Blood Advances
Blood Adv (2018) 2 (17): 2187–2198.
https://doi.org/10.1182/bloodadvances.2018019166
Published: 2018
Includes: Supplemental data
Journal Articles

Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets

Caterina Casari, David S. Paul, Sophie Susen, Cécile Lavenu-Bombled, Annie Harroche, Raymond Piatt, Kathryn O. Poe, Robert H. Lee, Marijke Bryckaert, Olivier D. Christophe, Peter J. Lenting, Cécile V. Denis, Wolfgang Bergmeier
Journal: Blood Advances
Blood Adv (2018) 2 (12): 1417–1428.
https://doi.org/10.1182/bloodadvances.2017014290
Published: 2018
Includes: Supplemental data
Journal Articles

Defective RAB1B-related megakaryocytic ER-to-Golgi transport in RUNX1 haplodeficiency: impact on von Willebrand factor

Gauthami Jalagadugula, Lawrence E. Goldfinger, Guangfen Mao, Michele P. Lambert, A. Koneti Rao
Journal: Blood Advances
Blood Adv (2018) 2 (7): 797–806.
https://doi.org/10.1182/bloodadvances.2017014274
Published: 2018
Includes: Supplemental data
Journal Articles

Platelet dense granules begin to selectively accumulate mepacrine during proplatelet formation

Hayley A. Hanby, Jialing Bao, Ji-Yoon Noh, Danuta Jarocha, Mortimer Poncz, Mitchell J. Weiss, Michael S. Marks
Journal: Blood Advances
Blood Adv (2017) 1 (19): 1478–1490.
https://doi.org/10.1182/bloodadvances.2017006726
Published: 2017
Includes: Supplemental data