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Journal Articles

Canonical Wnt: a safeguard and threat for erythropoiesis

Rosa A. Krimpenfort, Micha Nethe
Journal: Blood Advances
Blood Adv (2021) 5 (18): 3726–3735.
https://doi.org/10.1182/bloodadvances.2021004845
Published: 2021
Journal Articles

Enhanced self-renewal of human long-term hematopoietic stem cells by a sulfamoyl benzoate derivative targeting p18 INK4C

Yinghui Li, Wenshan Zhang, Yu Zhang, Yahui Ding, Ming Yang, Mei He, Xiaolei Liu, Jiali Gu, Shiqi Xu, Zhiwei Feng, Yafang Li, Jingjing Yin, Huier Gao, Henan Song, Hui Xu, Chaoqun Wang, Qing Ji, Shihui Ma, Wanzhu Yang, Weiping Yuan, Xiang-Qun Xie, Tao Cheng, Yingdai Gao
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3362–3372.
https://doi.org/10.1182/bloodadvances.2020004054
Published: 2021
Includes: Supplemental data
Journal Articles

Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis

Derek C. H. Chan, Joshua Xu, Ana Vujovic, Nicholas Wong, Victor Gordon, Laura P. M. H. de Rooij, Steven Moreira, Cailin E. Joyce, Jose La Rose, María-José Sandí, Bradley W. Doble, Carl D. Novina, Robert K. Rottapel, Kristin J. Hope
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3120–3133.
https://doi.org/10.1182/bloodadvances.2020002539
Published: 2021
Includes: Supplemental data
Journal Articles

Transfer to the clinic: refining forward programming of hPSCs to megakaryocytes for platelet production in bioreactors

Amanda L. Evans, Amanda Dalby, Holly R. Foster, Daniel Howard, Amie K. Waller, Momal Taimoor, Moyra Lawrence, Souradip Mookerjee, Marcus Lehmann, Annie Burton, Jorge Valdez, Jonathan Thon, Joseph Italiano, Thomas Moreau, Cedric Ghevaert
Journal: Blood Advances
Blood Adv (2021) 5 (7): 1977–1990.
https://doi.org/10.1182/bloodadvances.2020003236
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Autophagy is dispensable for the maintenance of hematopoietic stem cells in neonates

Michihiro Hashimoto, Terumasa Umemoto, Ayako Nakamura-Ishizu, Takayoshi Matsumura, Tomomasa Yokomizo, Maiko Sezaki, Hitoshi Takizawa, Toshio Suda
Journal: Blood Advances
Blood Adv (2021) 5 (6): 1594–1604.
https://doi.org/10.1182/bloodadvances.2020002410
Published: 2021
Includes: Supplemental data
Journal Articles

JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells

Hannah Lawson, Catarina Sepulveda, Louie N. van de Lagemaat, Jozef Durko, Melania Barile, Andrea Tavosanis, Elise Georges, Alena Shmakova, Penny Timms, Roderick N. Carter, Lewis Allen, Joana Campos, Milica Vukovic, Amelie V. Guitart, Peter Giles, Marie O’Shea, Douglas Vernimmen, Nicholas M. Morton, Neil P. Rodrigues, Berthold Göttgens, Christopher J. Schofield, Andreas Lengeling, Dónal O’Carroll, Kamil R. Kranc
Journal: Blood Advances
Blood Adv (2021) 5 (3): 889–899.
https://doi.org/10.1182/bloodadvances.2020002702
Published: 2021
Includes: Supplemental data
Journal Articles

Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation

Antonio Maglitto, Samanta A. Mariani, Emma de Pater, Carmen Rodriguez-Seoane, Chris S. Vink, Xianhua Piao, Mari-Liis Lukke, Elaine Dzierzak
Journal: Blood Advances
Blood Adv (2021) 5 (3): 829–842.
https://doi.org/10.1182/bloodadvances.2020003693
Published: 2021
Includes: Supplemental data
Journal Articles

Sustained fetal hematopoiesis causes juvenile death from leukemia: evidence from a dual-age–specific mouse model

Nitza Vara, Yuqing Liu, Yan Yan, Shelly Y. Lensing, Natalia Colorado, Delli Robinson, Jingliao Zhang, Xin Zhang, Erich A. Peterson, Nicholas J. Baltz, Daohong Zhou, Alice Bertaina, Donald J. Johann, Jr, Peter D. Emanuel, Y. Lucy Liu
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3728–3740.
https://doi.org/10.1182/bloodadvances.2020002326
Published: 2020
Includes: Supplemental data
Journal Articles

High prevalence of clonal hematopoiesis in the blood and bone marrow of healthy volunteers

Clinical Trials & Observations
Hélène Guermouche, Noémie Ravalet, Nathalie Gallay, Caroline Deswarte, Amelie Foucault, Jenny Beaud, Emmanuelle Rault, Emeline Saindoy, Sébastien Lachot, Jean-Alain Martignoles, Valérie Gissot, Ludovic Suner, Emmanuel Gyan, François Delhommeau, Olivier Herault, Pierre Hirsch
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3550–3557.
https://doi.org/10.1182/bloodadvances.2020001582
Published: 2020
Includes: Supplemental data
Journal Articles

Reduced-intensity single-unit unrelated cord blood transplant with optional immune boost for nonmalignant disorders

Clinical Trials & Observations
Mark T. Vander Lugt, Xiaohua Chen, Maria L. Escolar, Beth A. Carella, Jessie L. Barnum, Randy M. Windreich, Memphis J. Hill, Michelle Poe, Rebecca A. Marsh, Heather Stanczak, Elizabeth O. Stenger, Paul Szabolcs
Journal: Blood Advances
Blood Adv (2020) 4 (13): 3041–3052.
https://doi.org/10.1182/bloodadvances.2020001940
Published: 2020
Includes: Supplemental data
Journal Articles

Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita

Siddharth Shukla, Ho-Chang Jeong, Christopher M. Sturgeon, Roy Parker, Luis Francisco Zirnberger Batista
Journal: Blood Advances
Blood Adv (2020) 4 (12): 2717–2722.
https://doi.org/10.1182/bloodadvances.2020001848
Published: 2020
Includes: Supplemental data
Journal Articles

Sequencing of RNA in single cells reveals a distinct transcriptome signature of hematopoiesis in GATA2 deficiency

Zhijie Wu, Shouguo Gao, Carrie Diamond, Sachiko Kajigaya, Jinguo Chen, Rongye Shi, Cindy Palmer, Amy P. Hsu, Katherine R. Calvo, Dennis D. Hickstein, Steven M. Holland, Neal S. Young
Journal: Blood Advances
Blood Adv (2020) 4 (12): 2702–2716.
https://doi.org/10.1182/bloodadvances.2019001352
Published: 2020
Includes: Supplemental data
Journal Articles

Clonal hematopoiesis in angioimmunoblastic T-cell lymphoma with divergent evolution to myeloid neoplasms

Natasha E. Lewis, Kseniya Petrova-Drus, Sarah Huet, Zachary D. Epstein-Peterson, Qi Gao, Allison E. Sigler, Jeeyeon Baik, Neval Ozkaya, Alison J. Moskowitz, Anita Kumar, Steven M. Horwitz, Yanming Zhang, Maria E. Arcila, Ross L. Levine, Mikhail Roshal, Ahmet Dogan, Wenbin Xiao
Journal: Blood Advances
Blood Adv (2020) 4 (10): 2261–2271.
https://doi.org/10.1182/bloodadvances.2020001636
Published: 2020
Includes: Supplemental data
Journal Articles

Clonal hematopoiesis predicts development of therapy-related myeloid neoplasms post–autologous stem cell transplantation

Clinical Trials & Observations
Johannes Frasez Soerensen, Anni Aggerholm, Gitte Birk Kerndrup, Marcus Celik Hansen, Ina Kathrine Lykke Ewald, Marie Bill, Lene Hyldahl Ebbesen, Carina Agerbo Rosenberg, Peter Hokland, Maja Ludvigsen, Anne Stidsholt Roug
Journal: Blood Advances
Blood Adv (2020) 4 (5): 885–892.
https://doi.org/10.1182/bloodadvances.2019001157
Published: 2020
Includes: Supplemental data
Journal Articles

Single-cell mutational profiling enhances the clinical evaluation of AML MRD

Clinical Trials & Observations
Asiri Ediriwickrema, Alexey Aleshin, Johannes G. Reiter, M. Ryan Corces, Thomas Köhnke, Melissa Stafford, Michaela Liedtke, Bruno C. Medeiros, Ravindra Majeti
Journal: Blood Advances
Blood Adv (2020) 4 (5): 943–952.
https://doi.org/10.1182/bloodadvances.2019001181
Published: 2020
Includes: Supplemental data
Journal Articles

Stem cell donors should not be screened for clonal hematopoiesis

Christopher J. Gibson, R. Coleman Lindsley
Journal: Blood Advances
Blood Adv (2020) 4 (4): 789–792.
https://doi.org/10.1182/bloodadvances.2019000395
Published: 2020
Journal Articles

Highly multiplexed proteomic assessment of human bone marrow in acute myeloid leukemia

Haydar Çelik, Katherine E. Lindblad, Bogdan Popescu, Gege Gui, Meghali Goswami, Janet Valdez, Christin DeStefano, Catherine Lai, Julie Thompson, Jack Y. Ghannam, Giovanna Fantoni, Angélique Biancotto, Julián Candia, Foo Cheung, Gauthaman Sukumar, Clifton L. Dalgard, Richard H. Smith, Andre Larochelle, Laura W. Dillon, Christopher S. Hourigan
Journal: Blood Advances
Blood Adv (2020) 4 (2): 367–379.
https://doi.org/10.1182/bloodadvances.2019001124
Published: 2020
Includes: Supplemental data
Journal Articles

The stem cell–specific long noncoding RNA HOXA10-AS in the pathogenesis of KMT2A -rearranged leukemia

Sina Al-Kershi, Raj Bhayadia, Michelle Ng, Lonneke Verboon, Stephan Emmrich, Lucie Gack, Adrian Schwarzer, Till Strowig, Dirk Heckl, Jan-Henning Klusmann
Journal: Blood Advances
Blood Adv (2019) 3 (24): 4252–4263.
https://doi.org/10.1182/bloodadvances.2019032029
Published: 2019
Includes: Supplemental data
Journal Articles

Longitudinal assessment of clonal mosaicism in human hematopoiesis via mitochondrial mutation tracking

Caleb A. Lareau, Leif S. Ludwig, Vijay G. Sankaran
Journal: Blood Advances
Blood Adv (2019) 3 (24): 4161–4165.
https://doi.org/10.1182/bloodadvances.2019001196
Published: 2019
Includes: Supplemental data
Journal Articles

Non-del(5q) myelodysplastic syndromes–associated loci detected by SNP-array genome-wide association meta-analysis

Kathy L. McGraw, Chia-Ho Cheng, Y. Ann Chen, Hsin-An Hou, Björn Nilsson, Giulio Genovese, Thomas Cluzeau, Andrea Pellagatti, Bartlomiej P. Przychodzen, Mar Mallo, Leonor Arenillas, Azim Mohamedali, Lionel Adès, David A. Sallman, Eric Padron, Lubomir Sokol, Chimene Moreilhon, Sophie Raynaud, Hwei-Fang Tien, Jacqueline Boultwood, Benjamin L. Ebert, Francesc Sole, Pierre Fenaux, Ghulam J. Mufti, Jaroslaw P. Maciejewski, Peter A. Kanetsky, Alan F. List
Journal: Blood Advances
Blood Adv (2019) 3 (22): 3579–3589.
https://doi.org/10.1182/bloodadvances.2019000922
Published: 2019
Includes: Supplemental data