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Journal Articles

Dual-action CXCR4-targeting liposomes in leukemia: function blocking and drug delivery

Catriona McCallion, Anna D. Peters, Andrew Booth, Karen Rees-Unwin, Julie Adams, Raisa Rahi, Alain Pluen, Claire V. Hutchinson, Simon J. Webb, John Burthem
Journal: Blood Advances
Blood Adv (2019) 3 (14): 2069–2081.
https://doi.org/10.1182/bloodadvances.2019000098
Published: 2019
Includes: Supplemental data
Journal Articles

Dysregulated megakaryocyte distribution associated with nestin + mesenchymal stem cells in immune thrombocytopenia

Min Wang, Ru Feng, Jia-min Zhang, Lin-lin Xu, Fei-er Feng, Chen-cong Wang, Qian-ming Wang, Xiao-lu Zhu, Yun He, Jing Xue, Hai-xia Fu, Meng Lv, Yuan Kong, Ying-jun Chang, Lan-ping Xu, Kai-yan Liu, Xiao-jun Huang, Xiao-hui Zhang
Journal: Blood Advances
Blood Adv (2019) 3 (9): 1416–1428.
https://doi.org/10.1182/bloodadvances.2018026690
Published: 2019
Includes: Supplemental data
Journal Articles

Sipa1 deficiency–induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm

Pingnan Xiao, Monika Dolinska, Lakshmi Sandhow, Makoto Kondo, Anne-Sofie Johansson, Thibault Bouderlique, Ying Zhao, Xidan Li, Marios Dimitriou, George Z. Rassidakis, Eva Hellström-Lindberg, Nagahiro Minato, Julian Walfridsson, David T. Scadden, Mikael Sigvardsson, Hong Qian
Journal: Blood Advances
Blood Adv (2018) 2 (5): 534–548.
https://doi.org/10.1182/bloodadvances.2017013599
Published: 2018
Includes: Supplemental data
Journal Articles

Combination of the low anticoagulant heparin CX-01 with chemotherapy for the treatment of acute myeloid leukemia

Clinical Trials & Observations
Tibor J. Kovacsovics, Alice Mims, Mohamed E. Salama, Jeremy Pantin, Narayanam Rao, Ken M. Kosak, Peter Ahorukomeye, Martha J. Glenn, Michael W. N. Deininger, Kenneth M. Boucher, Linda M. Bavisotto, Gerardo Gutierrez-Sanchez, Thomas P. Kennedy, Stephen G. Marcus, Paul J. Shami
Journal: Blood Advances
Blood Adv (2018) 2 (4): 381–389.
https://doi.org/10.1182/bloodadvances.2017013391
Published: 2018
Journal Articles

Two distinct CXCR4 antagonists mobilize progenitor cells in mice by different mechanisms

Andia N. Redpath, Moïra François, Suet-Ping Wong, Dominique Bonnet, Sara M. Rankin
Journal: Blood Advances
Blood Adv (2017) 1 (22): 1934–1943.
https://doi.org/10.1182/bloodadvances.2017006064
Published: 2017
Includes: Supplemental data
Journal Articles

A novel CXCR4 antagonist IgG1 antibody (PF-06747143) for the treatment of hematologic malignancies

Shu-Hui Liu, Yin Gu, Bernadette Pascual, Zhengming Yan, Max Hallin, Cathy Zhang, Conglin Fan, Wenlian Wang, Justine Lam, Mary E. Spilker, Rolla Yafawi, Eileen Blasi, Brett Simmons, Nanni Huser, Wei-Hsien Ho, Kevin Lindquist, Thomas-Toan Tran, Jyothirmayee Kudaravalli, Jing-Tyan Ma, Gretchen Jimenez, Ishita Barman, Colleen Brown, Sherman Michael Chin, Maria J. Costa, David Shelton, Tod Smeal, Valeria R. Fantin, Flavia Pernasetti
Journal: Blood Advances
Blood Adv (2017) 1 (15): 1088–1100.
https://doi.org/10.1182/bloodadvances.2016003921
Published: 2017
Includes: Supplemental data
Journal Articles

High CD123 levels enhance proliferation in response to IL-3, but reduce chemotaxis by downregulating CXCR4 expression

Nicole L. Wittwer, Gabriela Brumatti, Ceilidh Marchant, Jarrod J. Sandow, Melanie K. Pudney, Mara Dottore, Richard J. D’Andrea, Angel F. Lopez, Paul G. Ekert, Hayley S. Ramshaw
Journal: Blood Advances
Blood Adv (2017) 1 (15): 1067–1079.
https://doi.org/10.1182/bloodadvances.2016002931
Published: 2017
Includes: Supplemental data