In conclusion we should like to emphasize that the classical hemosiderin of the histologist is not a single or unique substance.8 The constitution of this material is quite variable. Removal of hemosiderin granules from cells for chemical analysis demands careful control based on morphologic criteria and is, in any case, not a substitute, but a concomitant of examination in situ in cells. One should bear in mind that in its natural state hemosiderin occurs in living tissues, not as a test tube isolate, or as a thin section.

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© 1965 by American Society of Hematology, Inc.
1965
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